Amylyx PharmaceuticalsAMLX
13F holders, Q1 2026 (March 31)171holders −9
21new positions
34sold out
5famous investors
$13.90avg. 13F price*
At the end of Q1 2026, 171 institutions reported holding Amylyx Pharmaceuticals Inc. (AMLX) in their 13F filings, down 9 from Q4 2025. 21 opened new positions and 34 sold out. The largest holders were FMR LLC ($231.2M), BlackRock, Inc. ($122.7M) and Perceptive Advisors LLC ($115.2M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Amylyx Pharmaceuticals Inc.
- CUSIP
- 03237H101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 21 | $24.0M |
| Exits | 34 | $44.1M |
All 13F filers, Q4 2025 → Q1 2026: 7,647,211 shares bought and 7,056,283 shares sold, net +590,928 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 171 holders
| FMR LLC | 0.01% | Add +0.7% | 16,630,541 | $231.2M |
| BlackRock, Inc. | 0.00% | Reduce -2.5% | 8,828,836 | $122.7M |
| Perceptive Advisors LLC | 2.28% | No change | 8,284,882 | $115.2M |
| TCG Crossover Management, LLC | 2.48% | No change | 6,243,812 | $86.8M |
| Commodore Capital LP | 4.54% | No change | 5,650,000 | $78.5M |
| Janus Henderson Group PLC | 0.03% | Add +11.7% | 4,986,073 | $69.3M |
| Saturn V Capital Management LP | 10.95% | Reduce -3.3% | 4,349,885 | $60.5M |
| Vanguard Capital Management LLC | 0.00% | — | 4,141,575 | $57.6M |
| Adage Capital Partners Gp, L.L.C. | 0.08% | Add +28.2% | 3,560,764 | $49.5M |
| First Light Asset Management, LLC | 3.97% | Reduce -4.9% | 3,190,645 | $44.3M |
| Driehaus Capital Management LLC | 0.31% | Reduce -3.9% | 2,987,147 | $41.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +0.5% | 2,625,991 | $36.5M |
| State Street Corp. | 0.00% | Add +14.2% | 2,363,161 | $32.8M |
| Franklin Resources Inc. | 0.01% | Add +88.5% | 2,261,569 | $31.4M |
| Geode Capital Management, LLC | 0.00% | Add +2.1% | 2,210,932 | $30.7M |
| Morgan Stanley | 0.00% | Reduce -7.8% | 2,175,547 | $30.2M |
| Almitas Capital LLC | 6.67% | No change | 2,122,597 | $29.5M |
| Great Point Partners LLC | 5.96% | No change | 1,750,000 | $24.3M |
| Jones Hill Capital LP | 4.76% | — | 1,598,794 | $22.2M |
| 683 Capital Management, LLC | 2.08% | Reduce -7.3% | 1,530,000 | $21.3M |
| Eventide Asset Management, LLC | 0.35% | Add +0.1% | 1,513,958 | $21.0M |
| Bank of America Corp. | 0.00% | Reduce -0.4% | 1,330,689 | $18.5M |
| Deutsche Bank AG | 0.01% | Reduce -4.9% | 1,267,785 | $17.6M |
| Siren, L.L.C. | 0.47% | New | 1,230,000 | $17.1M |
| Balyasny Asset Management L.P. | 0.03% | Add +28.9% | 1,107,271 | $15.4M |
| ADAR1 Capital Management, LLC | 0.84% | Add +12.4% | 1,000,604 | $13.9M |
| Barclays PLC | 0.00% | Add +229.2% | 971,854 | $13.5M |
| Vanguard Portfolio Management LLC | 0.00% | — | 944,781 | $13.1M |
| Dimensional Fund Advisors LP | 0.00% | Add +17.1% | 903,192 | $12.5M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.03% | Reduce -13.5% | 868,325 | $12.1M |
| Woodline Partners LP | 0.04% | Add +0.1% | 845,800 | $11.8M |
| Boxer Capital Management, LLC | 1.46% | No change | 800,000 | $11.1M |
| Northern Trust Corp. | 0.00% | Reduce -16.8% | 779,908 | $10.8M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.5% | 716,225 | $10.0M |
| Qube Research & Technologies Ltd | 0.01% | Add +70.1% | 702,236 | $9.8M |
| Logos Global Management LP | 0.50% | Reduce -26.3% | 700,000 | $9.7M |
| Stempoint Capital LP | 1.79% | Add +18.5% | 669,685 | $9.3M |
| Parkman Healthcare Partners LLC | 0.90% | Add +62.8% | 621,458 | $8.6M |
| Jupiter Asset Management Ltd. | 0.04% | Add +3705.4% | 592,654 | $8.2M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 586,152 | $8.1M |
| Nantahala Capital Management, LLC | 0.47% | Reduce -35.9% | 535,684 | $7.4M |
| Rock Springs Capital Management LP | 0.41% | No change | 499,764 | $6.9M |
| Citadel Advisors | 0.00% | Add +19.3% | 411,532 | $5.7M |
| Federated Hermes, Inc. | 0.01% | Reduce -20.5% | 363,546 | $5.1M |
| HighVista Strategies LLC | 1.35% | Add +47.4% | 352,085 | $4.9M |
| Cormorant Asset Management, LP | 0.25% | Reduce -12.5% | 350,000 | $4.9M |
| UBS Group AG | 0.00% | Reduce -40.3% | 324,319 | $4.5M |
| Tetragon Partners GP Ltd | 0.87% | Add +16.5% | 317,877 | $4.4M |
| iA Global Asset Management Inc. | 0.06% | New | 304,786 | $4.2M |
| Nuveen, LLC | 0.00% | Reduce -6.7% | 264,897 | $3.7M |
| Bank of New York Mellon Corp | 0.00% | Add +15.5% | 251,104 | $3.5M |
| Wellington Management Group LLP | 0.00% | Add +7.0% | 241,552 | $3.4M |
| SummitTX Capital, L.P. | 0.10% | Add +3.9% | 227,010 | $3.2M |
| Aldebaran Capital, LLC | 2.11% | Reduce -0.3% | 197,892 | $2.8M |
| Invesco Ltd. | 0.00% | Reduce -2.4% | 171,620 | $2.4M |
| Two Sigma Investments, LP | 0.00% | Reduce -53.0% | 161,945 | $2.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +58.9% | 157,089 | $2.2M |
| Acuta Capital Partners, LLC | 1.49% | Reduce -54.7% | 151,067 | $2.1M |
| JPMorgan Chase & Co. | 0.00% | Add +139.9% | 159,663 | $2.0M |
| PFM Health Sciences, LP | 0.22% | Add +8.0% | 145,275 | $2.0M |
| Alpha Wave Global, LP | 0.25% | Reduce -55.2% | 142,336 | $2.0M |
| Swiss National Bank | 0.00% | Reduce -19.4% | 130,300 | $1.8M |
| T. Rowe Price Associates Inc. | 0.00% | Add +12.9% | 121,439 | $1.7M |
| Squarepoint Ops LLC | 0.00% | Add +50.0% | 114,877 | $1.6M |
| Elmind Capital, LP | 0.44% | No change | 112,000 | $1.6M |
| Rhumbline Advisers | 0.00% | Add +9.3% | 108,467 | $1.5M |
| Point72 Asset Management | 0.00% | Reduce -68.2% | 106,535 | $1.5M |
| Alps Advisors Inc. | 0.01% | Reduce -0.2% | 89,983 | $1.3M |
| Sei Investments Co. | 0.00% | Add +61.3% | 85,279 | $1.2M |
| Schonfeld Strategic Advisors LLC | 0.01% | Add +269.5% | 77,794 | $1.1M |
| Wells Fargo & Company | 0.00% | Reduce -48.7% | 75,083 | $1.0M |
| D. E. Shaw & Co. | 0.00% | Add +1.4% | 74,230 | $1.0M |
| State of Wisconsin Investment Board | 0.00% | Reduce -14.4% | 72,061 | $1.0M |
| Alliancebernstein L.P. | 0.00% | Add +13.0% | 80,800 | $976K |
| California State Teachers Retirement System | 0.00% | Reduce -17.8% | 65,002 | $904K |
| Walleye Capital LLC | 0.01% | Add +975.1% | 61,711 | $858K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -9.3% | 59,346 | $825K |
| Legal & General Group Plc | 0.00% | Reduce -23.2% | 55,773 | $775K |
| Campbell & CO Investment Adviser LLC | 0.04% | Reduce -30.9% | 54,422 | $756K |
| Informed Momentum Co LLC | 0.09% | No change | 53,256 | $740K |
| MetLife Investment Management, LLC | 0.00% | Add +3.9% | 51,587 | $717K |
| Maven Securities LTD | 0.04% | New | 50,000 | $695K |
| Numerai GP LLC | 0.07% | Reduce -56.9% | 48,553 | $675K |
| Vanguard Global Advisers, LLC | 0.00% | — | 47,851 | $665K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 43,283 | $602K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +3.4% | 42,553 | $591K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +13.7% | 40,790 | $567K |
| Susquehanna International Group, LLP | 0.00% | Reduce -42.2% | 39,802 | $553K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +43.7% | 38,781 | $539K |
| Optimize Financial Inc. | 0.22% | New | 32,001 | $445K |
| Citigroup Inc. | 0.00% | Reduce -16.4% | 31,782 | $442K |
| Tudor Investment Corporation | 0.00% | Add +39.9% | 31,334 | $436K |
| AQR Capital Management | 0.00% | Add +4.5% | 29,089 | $404K |
| Integrated Quantitative Investments LLC | 0.07% | No change | 27,234 | $379K |
| Guggenheim Capital LLC | 0.00% | Add +1.1% | 25,513 | $355K |
| Intech Investment Management LLC | 0.00% | Reduce -22.1% | 24,921 | $346K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +15.5% | 24,072 | $335K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 23,752 | $330K |
| State of New Jersey Common Pension Fund D | 0.00% | New | 22,519 | $313K |
| New York State Common Retirement Fund | 0.00% | No change | 21,900 | $304K |
| Parsons Capital Management Inc. | 0.01% | No change | 21,645 | $301K |
| BNP Paribas Financial Markets | 0.00% | Reduce -16.1% | 21,140 | $294K |
| Virtus Investment Advisers, LLC | 0.08% | Add +2.5% | 20,815 | $289K |
| Premier Path Wealth Partners, LLC | 0.04% | No change | 20,265 | $282K |
| Brown Advisory Inc. | 0.00% | No change | 19,930 | $277K |
| Headlands Technologies LLC | 0.03% | Reduce -35.1% | 19,814 | $275K |
| China Universal Asset Management Co., Ltd. | 0.02% | Add +8.9% | 19,488 | $271K |
| ProShare Advisors LLC | 0.00% | Reduce -13.8% | 18,154 | $252K |
| Arizona State Retirement System | 0.00% | Reduce -21.0% | 18,099 | $252K |
| Creative Planning | 0.00% | New | 17,883 | $249K |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 17,713 | $246K |
| KLP Kapitalforvaltning As | 0.00% | No change | 17,400 | $242K |
| Profund Advisors LLC | 0.01% | Reduce -16.7% | 17,152 | $238K |
| Seven Fleet Capital Management LP | 0.07% | Add +44.1% | 16,671 | $232K |
| Voya Investment Management LLC | 0.00% | Reduce -0.1% | 15,227 | $212K |
| Prudential Financial Inc. | 0.00% | New | 14,120 | $196K |
| Verition Fund Management LLC | 0.00% | Reduce -55.0% | 13,264 | $184K |
| Amundi | 0.00% | New | 12,895 | $179K |
| Royal Bank of Canada | 0.00% | Reduce -20.8% | 12,383 | $172K |
| Landscape Capital Management, L.L.C. | 0.01% | No change | 12,226 | $170K |
| HSBC Holdings PLC | 0.00% | New | 11,414 | $157K |
| PSP Research LLC | 0.11% | Reduce -75.5% | 10,838 | $151K |
| Pictet Asset Management Holding SA | 0.00% | New | 10,768 | $150K |
| Victory Capital Management Inc. | 0.00% | Add +0.9% | 10,644 | $148K |
| Great Lakes Advisors, LLC | 0.00% | New | 10,380 | $144K |
| Valeo Financial Advisors, LLC | 0.00% | Reduce -33.3% | 10,000 | $139K |
| MAI Capital Management | 0.00% | New | 9,014 | $125K |
| Act Capital Management, LLC | 0.10% | No change | 9,000 | $125K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -2.3% | 7,913 | $110K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 7,203 | $100K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +7.3% | 5,728 | $80K |
| STRS Ohio | 0.00% | No change | 3,400 | $47K |
| GF Fund Management Co. LTD. | 0.00% | Add +13.8% | 2,455 | $34K |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 0.00% | No change | 1,803 | $29K |
| US Bancorp \de | 0.00% | Add +3.1% | 2,063 | $29K |
| State of Wyoming | 0.00% | Add +36.4% | 1,883 | $26K |
| KBC Group NV | 0.00% | New | 1,863 | $26K |
| Arax Advisory Partners | 0.00% | Reduce -41.4% | 1,494 | $21K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +7.8% | 1,418 | $20K |
| Rockefeller Capital Management L.P. | 0.00% | Add +388.1% | 1,274 | $18K |
| Cwm, LLC | 0.00% | Add +5.9% | 1,263 | $18K |
| Sterling Capital Management LLC | 0.00% | Reduce -30.1% | 1,137 | $16K |
| Steward Partners Investment Advisory, LLC | 0.00% | Reduce -33.3% | 1,000 | $14K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 922 | $13K |
| Westfuller Advisors, LLC | 0.00% | No change | 819 | $11K |
| Fifth Third Bancorp | 0.00% | New | 755 | $10K |
| Meeder Asset Management Inc. | 0.00% | Reduce -68.5% | 661 | $9K |
| Dunhill Financial, LLC | 0.00% | No change | 600 | $8K |
| Osaic Holdings, Inc. | 0.00% | Add +112.0% | 528 | $7K |
| GAMMA Investing LLC | 0.00% | Add +56.2% | 417 | $6K |
| J.Safra Asset Management Corp | 0.00% | Add +206.5% | 377 | $5K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -61.9% | 325 | $5K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -35.4% | 283 | $4K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +84.3% | 282 | $4K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 274 | $4K |
| Jones Financial Companies LLLP | 0.00% | Add +800.0% | 270 | $4K |
| Signaturefd, LLC | 0.00% | New | 254 | $4K |
| Larson Financial Group LLC | 0.00% | Add +390.2% | 201 | $3K |
| Eastern Bank | 0.00% | New | 200 | $3K |
| Harbour Investments, Inc. | 0.00% | No change | 90 | $1K |
| Stone House Investment Management, LLC | 0.00% | New | 73 | $1K |
| Rothschild Investment LLC | 0.00% | New | 55 | $765 |
| Salem Investment Counselors Inc. | 0.00% | New | 55 | $765 |
| Allworth Financial LP | 0.00% | Add +233.3% | 40 | $556 |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -99.1% | 36 | $500 |
| EverSource Wealth Advisors, LLC | 0.00% | Add +4.0% | 26 | $361 |
| Farther Finance Advisors, LLC | 0.00% | Add +10.0% | 22 | $316 |
| Essential Partners LLC | 0.00% | Reduce -11.8% | 15 | $209 |
| Ameritas Advisory Services, LLC | 0.00% | New | 3 | $42 |
| SBI Securities Co., Ltd. | 0.00% | No change | 1 | $14 |
| Covestor Ltd | 0.00% | New | 9 | $0 |
"% of holder's portfolio" is AMLX's weight in each manager's 13F, not the share of Amylyx Pharmaceuticals Inc. the manager owns.