Denali TherapeuticsDNLI
13F holders, Q3 2025 (September 30)240holders +10
33new positions
22sold out
7famous investors
$14.52avg. 13F price*
At the end of Q3 2025, 240 institutions reported holding Denali Therapeutics Inc. (DNLI) in their 13F filings, up 10 from Q2 2025. 33 opened new positions and 22 sold out. The largest holders were BlackRock, Inc. ($178.4M), Vanguard Group Inc. ($174.1M) and Baillie Gifford & Co. ($168.3M). 7 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Fisher (0.0% of Fisher Asset Management's portfolio).
- Company
- Denali Therapeutics Inc.
- CUSIP
- 24823R105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 33 | $38.0M |
| Exits | 22 | $14.5M |
All 13F filers, Q2 2025 → Q3 2025: 16,480,495 shares bought and 14,509,486 shares sold, net +1,971,009 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 240 holders
| BlackRock, Inc. | 0.00% | Add +2.0% | 12,289,626 | $178.4M |
| Vanguard Group Inc. | 0.00% | Add +1.5% | 11,992,918 | $174.1M |
| Baillie Gifford & Co. | 0.12% | Reduce -3.0% | 11,591,585 | $168.3M |
| FMR LLC | 0.00% | Reduce -15.9% | 6,340,316 | $92.1M |
| T. Rowe Price Investment Management, Inc. | 0.05% | Add +73.7% | 5,638,567 | $81.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.02% | Reduce -12.7% | 5,465,037 | $79.4M |
| State Street Corp. | 0.00% | Add +20.9% | 5,464,261 | $79.3M |
| Temasek Holdings (Private) Ltd | 0.27% | No change | 5,355,832 | $77.8M |
| Capital Research Global Investors | 0.01% | Add +0.2% | 4,760,858 | $69.1M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -30.6% | 4,568,368 | $66.3M |
| Baker Bros. Advisors LP | 0.39% | No change | 3,731,695 | $54.2M |
| Alliancebernstein L.P. | 0.02% | Add +12.2% | 3,520,414 | $51.1M |
| Geode Capital Management, LLC | 0.00% | Add +9.3% | 3,466,057 | $50.3M |
| Crestline Management, L.P. | 85.26% | Reduce -11.7% | 3,410,732 | $49.5M |
| Holocene Advisors, LP | 0.10% | Add +677.8% | 3,135,712 | $45.5M |
| Point72 Asset Management | 0.08% | Add +13.8% | 2,519,535 | $36.6M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -2.3% | 2,357,214 | $34.2M |
| Goldman Sachs Group Inc. | 0.00% | Add +16.0% | 2,163,705 | $31.4M |
| UBS Group AG | 0.01% | Add +111.7% | 2,012,353 | $29.2M |
| Stempoint Capital LP | 5.08% | Add +145.0% | 1,734,659 | $25.2M |
| Morgan Stanley | 0.00% | Add +28.8% | 1,689,492 | $24.5M |
| Fisher Asset Management | 0.01% | Add +7.6% | 1,631,496 | $23.7M |
| Millennium Management | 0.02% | Add +45.2% | 1,307,171 | $19.0M |
| Principal Financial Group Inc. | 0.01% | Add +18.5% | 1,271,190 | $18.5M |
| Northern Trust Corp. | 0.00% | Add +2.7% | 1,234,179 | $17.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +9.0% | 1,151,384 | $16.7M |
| Aberdeen Group plc | 0.03% | Add +23.4% | 1,113,586 | $16.2M |
| Foresite Capital Management VI LLC | 5.61% | New | 1,000,000 | $14.5M |
| Bank of America Corp. | 0.00% | Add +47.8% | 961,138 | $14.0M |
| Voloridge Investment Management, LLC | 0.05% | Add +21.5% | 936,230 | $13.6M |
| Casdin Capital, LLC | 1.08% | No change | 890,000 | $12.9M |
| Candriam S.C.A. | 0.06% | Reduce -1.3% | 833,582 | $12.1M |
| Siren, L.L.C. | 0.47% | No change | 821,513 | $11.9M |
| Bank of New York Mellon Corp | 0.00% | Add +1.3% | 800,747 | $11.6M |
| Marshall Wace, LLP | 0.01% | Reduce -44.0% | 787,029 | $11.4M |
| Masters Capital Management LLC | 1.75% | Add +25.0% | 750,000 | $10.9M |
| Citadel Advisors | 0.01% | Reduce -44.9% | 688,224 | $10.0M |
| Cercano Management LLC | 0.35% | No change | 625,000 | $9.1M |
| Ensign Peak Advisors, Inc | 0.01% | Add +12.8% | 534,071 | $7.8M |
| Segall Bryant & Hamill, LLC | 0.10% | Add +2.5% | 512,958 | $7.4M |
| Pictet Asset Management Holding SA | 0.01% | Add +20.3% | 499,162 | $7.2M |
| Yiheng Capital Management, L.P. | 2.26% | No change | 469,981 | $6.8M |
| Barclays PLC | 0.00% | Add +2.6% | 437,001 | $6.3M |
| Trexquant Investment LP | 0.06% | Add +294.1% | 430,566 | $6.3M |
| Palo Alto Investors LP | 1.10% | Add +70.1% | 408,006 | $5.9M |
| TD Asset Management Inc | 0.00% | Reduce -20.5% | 394,600 | $5.7M |
| Royal Bank of Canada | 0.00% | Reduce -4.6% | 372,176 | $5.4M |
| Clarius Group, LLC | 0.31% | Reduce -2.5% | 359,745 | $5.2M |
| American Century Companies Inc. | 0.00% | Add +12.3% | 357,341 | $5.2M |
| Hudson Bay Capital Management LP | 0.03% | Add +5.2% | 305,000 | $4.4M |
| Pier Capital, LLC | 0.68% | Reduce -4.3% | 301,171 | $4.4M |
| AXA Investment Managers S.A. | 0.01% | — | 294,732 | $4.3M |
| Marex Group Ltd | 0.05% | Add +11.1% | 291,000 | $4.2M |
| Nuveen, LLC | 0.00% | Reduce -52.2% | 284,777 | $4.1M |
| Swiss National Bank | 0.00% | Add +6.6% | 267,500 | $3.9M |
| Two Sigma Investments, LP | 0.01% | Add +1279.8% | 266,292 | $3.9M |
| BNP Paribas Financial Markets | 0.00% | Add +1283.8% | 264,061 | $3.8M |
| Lynx1 Capital Management LP | 0.77% | New | 261,687 | $3.8M |
| Boxer Capital Management, LLC | 1.16% | New | 250,000 | $3.6M |
| Invesco Ltd. | 0.00% | Add +13.5% | 249,467 | $3.6M |
| Cubist Systematic Strategies, LLC | 0.05% | Reduce -41.8% | 230,968 | $3.4M |
| Qube Research & Technologies Ltd | 0.00% | New | 227,990 | $3.3M |
| Schonfeld Strategic Advisors LLC | 0.02% | New | 226,203 | $3.3M |
| Jane Street Group, LLC | 0.00% | Add +163.6% | 224,903 | $3.3M |
| Campbell & CO Investment Adviser LLC | 0.24% | Add +51.9% | 216,774 | $3.1M |
| Schroder Investment Management Group | 0.00% | Reduce -45.8% | 209,595 | $3.0M |
| Deutsche Bank AG | 0.00% | Add +52.7% | 207,594 | $3.0M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -34.7% | 205,845 | $3.0M |
| Edmond DE Rothschild Holding S.A. | 0.05% | No change | 205,680 | $3.0M |
| Rhumbline Advisers | 0.00% | Reduce -5.2% | 201,565 | $2.9M |
| SCS Capital Management LLC | 0.03% | No change | 197,998 | $2.9M |
| Rafferty Asset Management, LLC | 0.01% | Add +49.6% | 182,886 | $2.7M |
| JPMorgan Chase & Co. | 0.00% | Reduce -8.7% | 175,021 | $2.5M |
| Teachers Retirement System of the State of Kentucky | 0.02% | No change | 171,553 | $2.5M |
| DAFNA Capital Management LLC | 0.61% | No change | 168,500 | $2.4M |
| Jump Financial, LLC | 0.03% | New | 166,399 | $2.4M |
| Legal & General Group Plc | 0.00% | Add +9.3% | 143,952 | $2.1M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +1.3% | 139,663 | $2.0M |
| Groupama Asset Managment | 0.03% | Reduce -22.7% | 135,758 | $2.0M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -3.6% | 129,887 | $1.9M |
| California State Teachers Retirement System | 0.00% | Add +8.6% | 129,526 | $1.9M |
| Edgestream Partners, L.P. | 0.05% | Reduce -63.9% | 123,819 | $1.8M |
| Woodline Partners LP | 0.01% | No change | 113,517 | $1.6M |
| Wells Fargo & Company | 0.00% | Add +16.2% | 104,179 | $1.5M |
| Algert Global LLC | 0.02% | Add +18.0% | 101,260 | $1.5M |
| Rhenman & Partners Asset Management AB | 0.16% | No change | 100,000 | $1.5M |
| Ameriprise Financial Inc. | 0.00% | Reduce -2.4% | 99,561 | $1.4M |
| Integrated Wealth Concepts LLC | 0.01% | Reduce -5.2% | 91,074 | $1.3M |
| Two Sigma Advisers, LP | 0.00% | Add +226.1% | 90,000 | $1.3M |
| Squarepoint Ops LLC | 0.00% | New | 80,518 | $1.2M |
| State of Wisconsin Investment Board | 0.00% | Add +0.6% | 80,126 | $1.2M |
| MetLife Investment Management, LLC | 0.01% | No change | 79,075 | $1.1M |
| Savvy Advisors, Inc. | 0.05% | Reduce -21.2% | 77,093 | $1.1M |
| AlphaQuest LLC | 0.07% | Add +224.1% | 74,422 | $1.1M |
| Alps Advisors Inc. | 0.01% | Reduce -10.4% | 70,230 | $1.0M |
| Engineers Gate Manager LP | 0.01% | Reduce -40.4% | 69,216 | $1.0M |
| Pier 88 Investment Partners LLC | 1.08% | Add +18.0% | 67,440 | $979K |
| XTX Topco Ltd | 0.05% | New | 65,345 | $949K |
| TT International Asset Management LTD | 0.18% | No change | 65,000 | $944K |
| Franklin Resources Inc. | 0.00% | Add +0.2% | 64,634 | $938K |
| Janus Henderson Group PLC | 0.00% | No change | 60,028 | $872K |
| Renaissance Technologies | 0.00% | Reduce -69.4% | 59,800 | $868K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 59,800 | $864K |
| Wellington Management Group LLP | 0.00% | Reduce -99.0% | 59,234 | $860K |
| Tudor Investment Corporation | 0.01% | Add +1.7% | 56,368 | $818K |
| Aquatic Capital Management LLC | 0.02% | New | 56,237 | $817K |
| Creative Planning | 0.00% | Reduce -4.9% | 54,834 | $796K |
| Ironwood Investment Management LLC | 0.33% | Reduce -0.8% | 52,786 | $766K |
| ADAR1 Capital Management, LLC | 0.07% | Add +44.2% | 51,516 | $748K |
| Dana Investment Advisors, Inc. | 0.02% | Add +42.6% | 50,716 | $736K |
| Knights of Columbus Asset Advisors LLC | 0.04% | Add +30.4% | 50,190 | $729K |
| Guggenheim Capital LLC | 0.01% | Reduce -4.5% | 49,525 | $719K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +8.9% | 47,459 | $689K |
| Intech Investment Management LLC | 0.01% | Reduce -34.9% | 46,797 | $679K |
| MAI Capital Management | 0.00% | No change | 46,526 | $676K |
| Jacobs Levy Equity Management, Inc. | 0.00% | New | 45,969 | $667K |
| Pathstone Holdings, LLC | 0.00% | Add +1.8% | 45,830 | $665K |
| Jennison Associates LLC | 0.00% | New | 45,445 | $660K |
| Cantor Fitzgerald, L. P. | 0.01% | New | 45,000 | $653K |
| Employees Retirement System of Texas | 0.01% | No change | 43,769 | $636K |
| Susquehanna International Group, LLP | 0.00% | Reduce -74.6% | 40,986 | $595K |
| Arizona State Retirement System | 0.00% | Add +7.1% | 40,813 | $593K |
| Profund Advisors LLC | 0.02% | Add +50.3% | 40,156 | $583K |
| Graham Capital Management, L.P. | 0.03% | Reduce -39.3% | 39,319 | $571K |
| New York State Common Retirement Fund | 0.00% | No change | 38,478 | $559K |
| Handelsbanken Fonder AB | 0.00% | No change | 38,300 | $556K |
| SG Americas Securities, LLC | 0.00% | New | 38,201 | $555K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +20.6% | 36,663 | $532K |
| Thrivent Financial for Lutherans | 0.00% | Reduce -47.6% | 35,619 | $517K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 34,168 | $496K |
| Teacher Retirement System of Texas | 0.00% | Reduce -4.0% | 33,827 | $491K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -3.4% | 32,415 | $471K |
| KLP Kapitalforvaltning As | 0.00% | Add +14.6% | 29,900 | $434K |
| ProShare Advisors LLC | 0.00% | Reduce -14.5% | 27,855 | $404K |
| Cinctive Capital Management LP | 0.02% | Add +14.3% | 27,792 | $404K |
| Erste Asset Management GmbH | 0.00% | No change | 26,900 | $391K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +22.1% | 26,223 | $381K |
| China Universal Asset Management Co., Ltd. | 0.03% | Reduce -12.2% | 25,629 | $372K |
| Raymond James Financial Inc. | 0.00% | Reduce -4.8% | 25,326 | $368K |
| Quantinno Capital Management LP | 0.00% | New | 24,707 | $359K |
| AQR Capital Management | 0.00% | Add +13.8% | 24,139 | $350K |
| EntryPoint Capital, LLC | 0.14% | New | 24,058 | $349K |
| Voya Investment Management LLC | 0.00% | Reduce -33.7% | 23,805 | $346K |
| Oxford Asset Management LLP | 0.11% | New | 22,231 | $323K |
| HighTower Advisors, LLC | 0.00% | Reduce -5.4% | 21,322 | $310K |
| Verition Fund Management LLC | 0.00% | Reduce -65.3% | 17,629 | $256K |
| Jain Global LLC | 0.00% | Add +20.2% | 17,414 | $253K |
| Prudential Financial Inc. | 0.00% | Add +0.4% | 16,938 | $246K |
| Breakwater Capital Group | 0.03% | Reduce -7.2% | 15,866 | $230K |
| Victory Capital Management Inc. | 0.00% | Reduce -67.0% | 15,064 | $219K |
| Citigroup Inc. | 0.00% | Reduce -80.4% | 14,936 | $217K |
| CIBC Bancorp USA Inc. | 0.00% | — | 14,118 | $205K |
| HSBC Holdings PLC | 0.00% | Add +39.4% | 14,004 | $201K |
| Russell Investments Group, Ltd. | 0.00% | Add +439.4% | 13,799 | $200K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 13,434 | $195K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -18.3% | 12,526 | $182K |
| Moneco Advisors, LLC | 0.02% | Add +19.1% | 12,478 | $181K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 12,238 | $178K |
| Aigen Investment Management, LP | 0.03% | Add +13.3% | 12,075 | $175K |
| Ameritas Investment Partners, Inc. | 0.00% | Reduce -18.2% | 11,065 | $161K |
| Empowered Funds, LLC | 0.00% | Reduce -25.5% | 11,037 | $160K |
| LPL Financial LLC | 0.00% | New | 10,648 | $155K |
| Intrust Bank NA | 0.01% | New | 10,575 | $154K |
| Xponance LLC | 0.00% | Add +0.5% | 10,400 | $151K |
| Sterling Capital Management LLC | 0.00% | Add +155.6% | 8,654 | $126K |
| PNC Financial Services Group, Inc. | 0.00% | Add +0.7% | 8,290 | $120K |
| Virtus Investment Advisers, LLC | 0.03% | Add +21.0% | 7,624 | $111K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -46.0% | 7,376 | $107K |
| Caption Management, LLC | 0.01% | New | 7,366 | $107K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.7% | 5,653 | $82K |
| KBC Group NV | 0.00% | No change | 4,495 | $65K |
| Quarry LP | 0.02% | New | 4,375 | $64K |
| Amalgamated Bank | 0.00% | No change | 4,305 | $63K |
| Assetmark, Inc. | 0.00% | Add +8.8% | 3,937 | $57K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -14.6% | 3,146 | $46K |
| Cwm, LLC | 0.00% | Add +5.4% | 2,397 | $35K |
| State of Wyoming | 0.00% | Add +2.6% | 2,154 | $31K |
| Johnson Financial Group, Inc. | 0.00% | New | 1,975 | $29K |
| Caitong International Asset Management Co., Ltd | 0.02% | Add +664.0% | 1,528 | $22K |
| Shell Asset Management Co. | 0.00% | Reduce -62.8% | 1,492 | $22K |
| Bartlett & Co. Wealth Management LLC | 0.00% | No change | 1,500 | $22K |
| Nisa Investment Advisors, LLC | 0.00% | Add +21.9% | 1,483 | $22K |
| Versant Capital Management, Inc | 0.00% | Add +14.8% | 1,476 | $21K |
| Osaic Holdings, Inc. | 0.00% | Reduce -13.0% | 1,388 | $21K |
| Comerica Bank | 0.00% | No change | 1,284 | $19K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +11.6% | 1,271 | $18K |
| Rockefeller Capital Management L.P. | 0.00% | New | 1,083 | $16K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 1,001 | $15K |
| Smartleaf Asset Management LLC | 0.00% | Add +110.1% | 954 | $14K |
| Optiver Holding B.V. | 0.00% | Add +0.3% | 896 | $13K |
| Quadrant Capital Group LLC | 0.00% | New | 782 | $11K |
| GAMMA Investing LLC | 0.00% | Reduce -2.7% | 729 | $11K |
| Nemes Rush Group LLC | 0.00% | No change | 700 | $10K |
| US Bancorp \de | 0.00% | Add +57.8% | 696 | $10K |
| Covestor Ltd | 0.00% | Reduce -0.2% | 579 | $8K |
| Lanark Financial, Inc. | 0.00% | No change | 532 | $8K |
| Groupe la Francaise | 0.00% | New | 620 | $8K |
| Daiwa Securities Group Inc. | 0.00% | No change | 475 | $7K |
| Parallel Advisors, LLC | 0.00% | Reduce -20.4% | 434 | $6K |
| NewEdge Advisors, LLC | 0.00% | No change | 400 | $6K |
| Huntington National Bank | 0.00% | Add +14.1% | 308 | $4K |
| Private Wealth Management Group, LLC | 0.00% | No change | 296 | $4K |
| City State Bank | 0.00% | No change | 250 | $4K |
| Signaturefd, LLC | 0.00% | Reduce -30.1% | 230 | $3K |
| Rothschild Investment LLC | 0.00% | Reduce -30.8% | 225 | $3K |
| Meeder Asset Management Inc. | 0.00% | New | 206 | $3K |
| Parkside Financial Bank & Trust | 0.00% | Add +26.0% | 189 | $3K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +44.4% | 166 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +16.3% | 143 | $2K |
| Farther Finance Advisors, LLC | 0.00% | Add +18.7% | 127 | $2K |
| Halbert Hargrove Global Advisors, LLC | 0.00% | New | 104 | $2K |
| Your Advocates Ltd., LLP | 0.00% | No change | 100 | $1K |
| Harbour Investments, Inc. | 0.00% | No change | 100 | $1K |
| Allworth Financial LP | 0.00% | Reduce -64.0% | 99 | $1K |
| Physician Wealth Advisors, Inc. | 0.00% | Reduce -45.7% | 76 | $1K |
| Rise Advisors, LLC | 0.00% | No change | 74 | $1K |
| TD Private Client Wealth LLC | 0.00% | New | 71 | $1K |
| Root Financial Partners, LLC | 0.00% | New | 70 | $1K |
| Bell Investment Advisors, Inc | 0.00% | Reduce -52.0% | 59 | $857 |
| True Wealth Design, LLC | 0.00% | No change | 56 | $814 |
| Guerra Advisors Inc | 0.00% | New | 50 | $726 |
| National Bank of Canada | 0.00% | Reduce -70.9% | 50 | $726 |
| Point72 (DIFC) Ltd | 0.00% | New | 43 | $622 |
| Blue Trust, Inc. | 0.00% | No change | 40 | $581 |
| Advisory Services Network, LLC | 0.00% | New | 39 | $566 |
| Sunbelt Securities, Inc. | 0.00% | New | 22 | $319 |
| SBI Securities Co., Ltd. | 0.00% | Add +340.0% | 22 | $319 |
| IFP Advisors, Inc | 0.00% | Add +0.0% | 9 | $131 |
| Fortitude Family Office, LLC | 0.00% | Reduce -78.0% | 9 | $131 |
| Private Wealth Asset Management, LLC | 0.00% | No change | 8 | $116 |
| SJS Investment Consulting Inc. | 0.00% | No change | 4 | $59 |
| Rialto Wealth Management, LLC | 0.00% | No change | 2 | $30 |
| HFM Investment Advisors, LLC | 0.00% | Reduce -33.3% | 2 | $29 |
| Truvestments Capital LLC | 0.00% | No change | 1 | $18 |
| Global Retirement Partners, LLC | 0.00% | Reduce -66.7% | 1 | $15 |
| Bay Harbor Wealth Management, LLC | 0.00% | No change | 1 | $14 |
| Simplex Trading, LLC | 0.00% | Reduce -98.4% | 41 | $0 |
| Avion Wealth | 0.00% | No change | 40 | $0 |
| Hemington Wealth Management | 0.00% | No change | 34 | $0 |
| Cloud Capital Management, LLC | 0.00% | New | 2 | $0 |
"% of holder's portfolio" is DNLI's weight in each manager's 13F, not the share of Denali Therapeutics Inc. the manager owns.