Structure TherapeuticsGPCR
13F holders, Q4 2024 (December 31)164holders +4
18new positions
22sold out
3famous investors
$27.13avg. 13F price*
At the end of Q4 2024, 164 institutions reported holding Structure Therapeutics Inc. (GPCR) in their 13F filings, up 4 from Q3 2024. 18 opened new positions and 22 sold out. The largest holders were Wellington Management Group LLP ($211.1M), FMR LLC ($164.9M) and Janus Henderson Group PLC ($112.8M). 3 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Structure Therapeutics Inc.
- CUSIP
- 86366E106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 18 | $21.2M |
| Exits | 22 | $139.9M |
All 13F filers, Q3 2024 → Q4 2024: 6,581,828 shares bought and 8,609,236 shares sold, net −2,027,408 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 164 holders
| Wellington Management Group LLP | 0.04% | Add +0.2% | 7,785,614 | $211.1M |
| FMR LLC | 0.01% | Reduce -0.8% | 6,078,746 | $164.9M |
| Janus Henderson Group PLC | 0.06% | Add +5.1% | 4,159,888 | $112.8M |
| Capital Research Global Investors | 0.02% | Add +0.2% | 3,537,341 | $95.9M |
| Deep Track Capital, LP | 2.85% | Add +129.4% | 2,800,000 | $75.9M |
| Driehaus Capital Management LLC | 0.46% | Reduce -18.6% | 2,057,410 | $55.8M |
| Federated Hermes, Inc. | 0.12% | Reduce -15.2% | 2,045,958 | $55.5M |
| BVF Inc. | 1.63% | Reduce -20.9% | 1,771,417 | $48.0M |
| Vestal Point Capital, LP | 2.77% | Add +50.0% | 1,725,000 | $46.8M |
| Capital International Investors | 0.01% | Add +6.8% | 1,619,081 | $43.9M |
| Ra Capital Management, L.P. | 0.55% | Reduce -20.0% | 1,517,418 | $41.2M |
| Citadel Advisors | 0.04% | Add +1.9% | 1,479,339 | $40.1M |
| Ameriprise Financial Inc. | 0.01% | Add +29.4% | 1,420,052 | $38.5M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -33.1% | 1,394,306 | $37.8M |
| FIL Ltd | 0.03% | Reduce -0.8% | 1,300,015 | $35.3M |
| Rock Springs Capital Management LP | 1.12% | Add +1.6% | 1,080,963 | $29.3M |
| TCG Crossover Management, LLC | 2.82% | No change | 1,063,000 | $28.8M |
| Principal Financial Group Inc. | 0.01% | Add +45.1% | 791,134 | $21.5M |
| Millennium Management | 0.02% | Reduce -17.6% | 751,013 | $20.4M |
| Franklin Resources Inc. | 0.01% | Add +4.5% | 738,090 | $20.0M |
| Logos Global Management LP | 2.22% | Reduce -44.0% | 700,000 | $19.0M |
| Casdin Capital, LLC | 1.27% | No change | 700,000 | $19.0M |
| Orbimed Advisors LLC | 0.37% | Add +69.9% | 652,028 | $17.7M |
| American Century Companies Inc. | 0.01% | Add +12.3% | 612,616 | $16.6M |
| BlackRock, Inc. | 0.00% | Reduce -10.2% | 610,585 | $16.6M |
| Marshall Wace, LLP | 0.02% | Add +339.6% | 583,207 | $15.8M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -18.2% | 582,865 | $15.8M |
| Catalio Capital Management, LP | 3.38% | — | 569,395 | $15.4M |
| Boxer Capital Management, LLC | 1.15% | — | 500,000 | $13.6M |
| Bellevue Group AG | 0.25% | Reduce -23.0% | 485,050 | $13.2M |
| Point72 Asset Management | 0.04% | Reduce -61.5% | 476,698 | $12.9M |
| Foresite Capital Management VI LLC | 5.08% | — | 420,000 | $11.4M |
| First Light Asset Management, LLC | 1.03% | Reduce -21.2% | 398,855 | $10.8M |
| Morgan Stanley | 0.00% | Add +138.3% | 387,176 | $10.5M |
| Deerfield Management Company, L.P. | 0.22% | Reduce -55.8% | 373,407 | $10.1M |
| Invesco Ltd. | 0.00% | Add +4.1% | 371,767 | $10.1M |
| Baker Bros. Advisors LP | 0.11% | Add +322.9% | 361,565 | $9.8M |
| Woodline Partners LP | 0.06% | Add +0.7% | 333,901 | $9.1M |
| Ensign Peak Advisors, Inc | 0.01% | Add +67.7% | 308,241 | $8.4M |
| Camber Capital Management LP | 0.32% | New | 300,000 | $8.1M |
| Ikarian Capital, LLC | 2.20% | Add +146.6% | 284,085 | $7.7M |
| HSG Holding Ltd | 0.31% | No change | 266,062 | $7.5M |
| UBS Group AG | 0.00% | Add +524.5% | 244,063 | $6.6M |
| ArrowMark Colorado Holdings LLC | 0.08% | Reduce -3.4% | 232,909 | $6.3M |
| Nantahala Capital Management, LLC | 0.42% | Add +29.2% | 221,000 | $6.0M |
| Superstring Capital Management LP | 5.16% | Reduce -4.5% | 216,811 | $5.9M |
| Candriam S.C.A. | 0.03% | Add +59.6% | 215,421 | $5.8M |
| Readystate Asset Management LP | 0.43% | Add +149.2% | 209,342 | $5.7M |
| Aberdeen Group plc | 0.01% | Reduce -21.1% | 171,388 | $4.6M |
| Handelsbanken Fonder AB | 0.02% | New | 165,000 | $4.5M |
| Silverarc Capital Management, LLC | 0.92% | Add +116.1% | 152,395 | $4.1M |
| Exome Asset Management LLC | 3.10% | Add +26.5% | 151,965 | $4.1M |
| CCG Wealth Management, LLC | 2.27% | New | 150,000 | $4.1M |
| Alliancebernstein L.P. | 0.00% | Reduce -10.3% | 142,825 | $3.9M |
| Pier Capital, LLC | 0.51% | Reduce -1.3% | 132,604 | $3.6M |
| Monashee Investment Management LLC | 0.50% | Reduce -17.3% | 132,000 | $3.6M |
| Royal Bank of Canada | 0.00% | Add +6.9% | 125,692 | $3.4M |
| RTW Investments, LP | 0.05% | No change | 125,000 | $3.4M |
| Jane Street Group, LLC | 0.01% | Add +198.7% | 116,013 | $3.1M |
| Barclays PLC | 0.00% | Add +42.6% | 115,671 | $3.1M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | — | 113,992 | $3.1M |
| TD Asset Management Inc | 0.00% | Reduce -53.4% | 88,882 | $2.4M |
| Boothbay Fund Management, LLC | 0.07% | Add +147.0% | 83,148 | $2.3M |
| Wexford Capital LP | 0.57% | Reduce -16.6% | 81,872 | $2.2M |
| Platinum Investment Management Ltd. | 0.12% | Add +30.9% | 74,900 | $2.0M |
| Banque Pictet & Cie SA | 0.02% | Reduce -8.5% | 74,177 | $2.0M |
| Citigroup Inc. | 0.00% | Add +4676.5% | 74,084 | $2.0M |
| Susquehanna International Group, LLP | 0.00% | Add +6.9% | 68,203 | $1.8M |
| Capital Fund Management S.A. | 0.02% | Add +33.9% | 67,135 | $1.8M |
| Fred Alger Management, LLC | 0.01% | Reduce -0.1% | 66,662 | $1.8M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -32.9% | 58,242 | $1.6M |
| Macquarie Group Ltd. | 0.00% | No change | 58,000 | $1.6M |
| Zimmer Partners, LP | 0.03% | Reduce -73.0% | 56,900 | $1.5M |
| Bank of America Corp. | 0.00% | Reduce -44.4% | 54,185 | $1.5M |
| Trexquant Investment LP | 0.02% | Add +592.0% | 52,876 | $1.4M |
| Bank of Montreal | 0.00% | Add +7.9% | 50,173 | $1.4M |
| Sectoral Asset Management Inc. | 0.89% | Add +101.9% | 49,250 | $1.3M |
| Alps Advisors Inc. | 0.01% | New | 46,300 | $1.3M |
| Geode Capital Management, LLC | 0.00% | Add +1.1% | 45,705 | $1.2M |
| Tema ETFs LLC | 0.50% | — | 44,343 | $1.2M |
| NEOS Investment Management LLC | 0.03% | Add +199.6% | 44,343 | $1.2M |
| TrueMark Investments, LLC | 0.36% | Reduce -7.4% | 42,127 | $1.1M |
| Exchange Traded Concepts, LLC | 0.02% | Reduce -1.6% | 40,435 | $1.1M |
| Nomura Asset Management Co. Ltd. | 0.00% | Add +25.5% | 36,925 | $1.0M |
| DAFNA Capital Management LLC | 0.25% | Add +4.4% | 35,500 | $963K |
| ADAR1 Capital Management, LLC | 0.20% | New | 35,319 | $958K |
| Russell Investments Group, Ltd. | 0.00% | Add +9.1% | 34,671 | $940K |
| JPMorgan Chase & Co. | 0.00% | Reduce -4.8% | 32,315 | $876K |
| Prelude Capital Management, LLC | 0.07% | Add +28.1% | 32,000 | $868K |
| Point72 Europe (London) LLP | 0.05% | Reduce -29.9% | 31,420 | $852K |
| Osaic Holdings, Inc. | 0.00% | Add +5821.5% | 30,792 | $835K |
| Twinbeech Capital LP | 0.01% | Add +34.3% | 28,268 | $767K |
| Voya Investment Management LLC | 0.00% | Reduce -44.5% | 25,940 | $703K |
| Mariner, LLC | 0.00% | New | 24,530 | $665K |
| Group One Trading LLC | 0.02% | Add +271.3% | 21,567 | $585K |
| Money Concepts Capital Corp. | 0.04% | Add +4.2% | 21,031 | $570K |
| Sofinnova Investments, Inc. | 0.04% | Reduce -46.1% | 20,892 | $567K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.01% | Add +8.4% | 19,520 | $529K |
| M&T Bank Corp | 0.00% | Add +100.0% | 18,110 | $492K |
| Teachers Retirement System of the State of Kentucky | 0.00% | No change | 17,651 | $479K |
| HighVista Strategies LLC | 0.18% | Reduce -44.6% | 17,561 | $476K |
| Simplex Trading, LLC | 0.01% | Reduce -18.4% | 17,346 | $470K |
| Engineers Gate Manager LP | 0.01% | Reduce -33.7% | 16,880 | $458K |
| J. Goldman & Co LP | 0.02% | New | 16,873 | $458K |
| Natixis Advisors, LLC | 0.00% | Reduce -45.8% | 14,459 | $392K |
| Griffin Asset Management, Inc. | 0.05% | No change | 14,450 | $392K |
| Walleye Trading LLC | 0.01% | Add +57.2% | 13,485 | $366K |
| EntryPoint Capital, LLC | 0.15% | Add +156.7% | 13,260 | $360K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +10.2% | 12,634 | $343K |
| Quinn Opportunity Partners LLC | 0.02% | No change | 12,000 | $325K |
| Walleye Capital LLC | 0.00% | New | 11,656 | $316K |
| LPL Financial LLC | 0.00% | Add +6.0% | 11,485 | $311K |
| BNP Paribas Financial Markets | 0.00% | New | 11,218 | $304K |
| Brandywine Managers, LLC | 0.32% | No change | 11,057 | $300K |
| State Street Corp. | 0.00% | Reduce -14.4% | 10,527 | $285K |
| Wells Fargo & Company | 0.00% | Add +202.5% | 10,103 | $274K |
| Bleichroeder LP | 0.07% | No change | 10,000 | $271K |
| PEAK6 LLC | 0.01% | — | 9,445 | $256K |
| Cinctive Capital Management LP | 0.01% | Reduce -71.8% | 9,065 | $246K |
| Janney Capital Management LLC | 0.02% | Add +36.4% | 9,007 | $244K |
| Spire Wealth Management | 0.01% | New | 8,949 | $243K |
| Allianz Asset Management GmbH | 0.00% | No change | 8,800 | $239K |
| Quadcap Wealth Management, LLC | 0.03% | Reduce -10.8% | 7,851 | $213K |
| Envestnet Asset Management Inc. | 0.00% | Add +12.8% | 7,403 | $201K |
| Caption Management, LLC | 0.01% | Reduce -27.7% | 5,600 | $152K |
| SG Americas Securities, LLC | 0.00% | Reduce -34.8% | 5,445 | $148K |
| Vestcor Inc | 0.00% | New | 4,700 | $127K |
| Jones Financial Companies LLLP | 0.00% | Add +29.8% | 4,228 | $115K |
| Headlands Technologies LLC | 0.01% | New | 4,160 | $113K |
| Bank Pictet & Cie (Europe) AG | 0.00% | Reduce -11.7% | 4,143 | $112K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +673.4% | 4,076 | $111K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -5.8% | 3,566 | $100K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -1.3% | 3,277 | $89K |
| Penserra Capital Management LLC | 0.00% | Add +4.5% | 3,107 | $84K |
| Assetmark, Inc. | 0.00% | Add +72.3% | 2,271 | $62K |
| Virtus Advisers, LLC | 0.02% | Add +25.5% | 2,242 | $61K |
| Steward Partners Investment Advisory, LLC | 0.00% | Add +2.7% | 2,114 | $57K |
| Jefferies Financial Group Inc. | 0.00% | Reduce -71.4% | 2,000 | $54K |
| FNY Investment Advisers, LLC | 0.02% | New | 1,500 | $40K |
| GF Fund Management Co. LTD. | 0.00% | — | 1,251 | $34K |
| GAMMA Investing LLC | 0.00% | Add +4155.6% | 1,149 | $31K |
| ANTIPODES PARTNERS Ltd | 0.00% | Add +115.0% | 1,034 | $28K |
| R Squared Ltd | 0.02% | — | 680 | $18K |
| Rhumbline Advisers | 0.00% | No change | 450 | $12K |
| North Star Investment Management Corp. | 0.00% | Reduce -66.3% | 330 | $9K |
| Summit Securities Group LLC | 0.00% | New | 246 | $7K |
| Daiwa Securities Group Inc. | 0.00% | No change | 226 | $6K |
| National Bank of Canada | 0.00% | Reduce -9.9% | 191 | $5K |
| Caitong International Asset Management Co., Ltd | 0.00% | — | 186 | $5K |
| Cwm, LLC | 0.00% | New | 100 | $3K |
| US Bancorp \de | 0.00% | Add +676.9% | 101 | $3K |
| Vermillion Wealth Management, Inc. | 0.00% | — | 100 | $3K |
| Signaturefd, LLC | 0.00% | No change | 100 | $3K |
| CoreCap Advisors, LLC | 0.00% | New | 77 | $2K |
| Clearstead Advisors, LLC | 0.00% | No change | 67 | $2K |
| Fairfield Financial Advisors, LTD | 0.00% | No change | 59 | $2K |
| Washington Trust Advisors, Inc. | 0.00% | No change | 41 | $1K |
| Aventura Private Wealth, LLC | 0.00% | — | 28 | $759 |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 20 | $542 |
| Global Retirement Partners, LLC | 0.00% | New | 10 | $271 |
| Cullen/Frost Bankers, Inc. | 0.00% | No change | 8 | $217 |
| Huntington National Bank | 0.00% | No change | 2 | $54 |
| Point72 Asia (Singapore) Pte. Ltd. | 0.00% | New | 1 | $23 |
| Capital Analysts, LLC | 0.00% | No change | 18 | $0 |
"% of holder's portfolio" is GPCR's weight in each manager's 13F, not the share of Structure Therapeutics Inc. the manager owns.