Protagonist TherapeuticsPTGX
13F holders, Q4 2024 (December 31)241holders +1
39new positions
40sold out
4famous investors
$38.60avg. 13F price*
At the end of Q4 2024, 241 institutions reported holding Protagonist Therapeutics Inc. (PTGX) in their 13F filings, up 1 from Q3 2024. 39 opened new positions and 40 sold out. The largest holders were BlackRock, Inc. ($381.5M), Farallon Capital Management, L.L.C. ($228.9M) and RTW Investments, LP ($212.2M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Protagonist Therapeutics Inc.
- CUSIP
- 74366E102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $97.6M |
| Exits | 40 | $119.5M |
All 13F filers, Q3 2024 → Q4 2024: 6,634,094 shares bought and 4,815,721 shares sold, net +1,818,373 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 241 holders
| BlackRock, Inc. | 0.01% | Reduce -3.3% | 9,884,617 | $381.5M |
| Farallon Capital Management, L.L.C. | 1.21% | Add +1.2% | 5,930,006 | $228.9M |
| RTW Investments, LP | 3.21% | Add +1.3% | 5,498,545 | $212.2M |
| Vanguard Group Inc. | 0.00% | Add +0.1% | 4,220,037 | $162.9M |
| State Street Corp. | 0.01% | Add +4.6% | 3,331,061 | $128.6M |
| Johnson & Johnson | 24.48% | No change | 2,449,183 | $94.5M |
| BVF Inc. | 2.49% | Add +2.7% | 1,900,015 | $73.3M |
| Pacer Advisors, Inc. | 0.16% | Add +8.2% | 1,876,466 | $72.4M |
| Jefferies Financial Group Inc. | 0.66% | Reduce -17.9% | 1,489,495 | $57.5M |
| T. Rowe Price Associates Inc. | 0.01% | Add +6.3% | 1,392,652 | $53.8M |
| Geode Capital Management, LLC | 0.00% | Add +0.2% | 1,377,063 | $53.2M |
| Perceptive Advisors LLC | 1.37% | Reduce -7.5% | 1,271,662 | $49.1M |
| ADAR1 Capital Management, LLC | 8.39% | Add +4.0% | 1,020,333 | $39.4M |
| Deep Track Capital, LP | 1.45% | New | 1,000,000 | $38.6M |
| Wellington Management Group LLP | 0.01% | Add +3025.4% | 940,077 | $36.3M |
| American Century Companies Inc. | 0.02% | Add +61.5% | 928,286 | $35.8M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -7.7% | 758,690 | $29.3M |
| Invesco Ltd. | 0.01% | Add +13.1% | 738,952 | $28.5M |
| Eversept Partners, LP | 2.70% | Add +52.5% | 678,787 | $26.2M |
| Northern Trust Corp. | 0.00% | Add +8.4% | 628,580 | $24.3M |
| Woodline Partners LP | 0.15% | Add +24.8% | 582,327 | $22.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +2.3% | 578,409 | $22.3M |
| JPMorgan Chase & Co. | 0.00% | Add +14.7% | 576,977 | $22.3M |
| Morgan Stanley | 0.00% | Reduce -14.1% | 540,315 | $20.9M |
| FMR LLC | 0.00% | Reduce -2.6% | 442,516 | $17.1M |
| Focus Partners Wealth | 0.04% | Reduce -0.3% | 425,557 | $16.4M |
| 683 Capital Management, LLC | 1.74% | Reduce -2.4% | 410,000 | $15.8M |
| Mangrove Partners Im, LLC | 1.86% | Reduce -10.0% | 395,383 | $15.3M |
| Kynam Capital Management, LP | 0.99% | Reduce -14.4% | 390,792 | $15.1M |
| Bank of New York Mellon Corp | 0.00% | Add +9.7% | 390,788 | $15.1M |
| Polar Capital Holdings Plc | 0.08% | No change | 350,000 | $13.5M |
| Toronto Dominion Bank | 0.03% | New | 340,974 | $13.2M |
| Driehaus Capital Management LLC | 0.11% | Reduce -23.7% | 339,698 | $13.1M |
| Principal Financial Group Inc. | 0.01% | Add +5.3% | 337,809 | $13.0M |
| Kennedy Capital Management LLC | 0.28% | Add +20.4% | 321,526 | $12.4M |
| Qube Research & Technologies Ltd | 0.02% | Reduce -3.3% | 312,319 | $12.1M |
| Skandinaviska Enskilda Banken AB (publ) | 0.05% | Add +35.0% | 310,650 | $12.0M |
| Raymond James Financial Inc. | 0.00% | — | 303,313 | $11.7M |
| Pictet Asset Management Holding SA | 0.01% | Add +3962.9% | 296,511 | $11.4M |
| Artia Global Partners LP | 4.57% | Add +136.1% | 293,851 | $11.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -21.8% | 287,911 | $11.1M |
| Soleus Capital Management, L.P. | 0.80% | New | 275,000 | $10.6M |
| Victory Capital Management Inc. | 0.01% | Add +84.1% | 240,817 | $9.3M |
| Dimensional Fund Advisors LP | 0.00% | Add +0.0% | 225,600 | $8.7M |
| Renaissance Technologies | 0.01% | Add +53.4% | 221,167 | $8.5M |
| Arrowstreet Capital, Limited Partnership | 0.01% | Add +36.7% | 216,069 | $8.3M |
| TD Asset Management Inc | 0.01% | Add +0.9% | 173,702 | $6.7M |
| Citadel Advisors | 0.01% | Add +3163.3% | 164,146 | $6.3M |
| Rhumbline Advisers | 0.01% | Reduce -1.4% | 161,964 | $6.3M |
| Man Group plc | 0.02% | Add +182.9% | 157,963 | $6.1M |
| Legal & General Group Plc | 0.00% | Reduce -0.3% | 152,562 | $5.9M |
| Nuveen Asset Management, LLC | 0.00% | Reduce -34.9% | 151,197 | $5.8M |
| AQR Capital Management | 0.01% | Add +9.4% | 150,097 | $5.8M |
| Public Sector Pension Investment Board | 0.02% | Add +18.8% | 148,489 | $5.7M |
| Stempoint Capital LP | 1.37% | New | 141,714 | $5.5M |
| Ameriprise Financial Inc. | 0.00% | Reduce -1.7% | 141,387 | $5.5M |
| First Trust Advisors LP | 0.00% | Add +0.0% | 140,951 | $5.4M |
| Deutsche Bank AG | 0.00% | Add +14.8% | 137,932 | $5.3M |
| Bank of America Corp. | 0.00% | Reduce -12.2% | 134,872 | $5.2M |
| UBS Group AG | 0.00% | Add +68.3% | 132,609 | $5.1M |
| Affinity Asset Advisors, LLC | 0.85% | New | 130,000 | $5.0M |
| Jacobs Levy Equity Management, Inc. | 0.02% | No change | 128,654 | $5.0M |
| Barclays PLC | 0.00% | Reduce -0.2% | 126,733 | $4.9M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.01% | No change | 125,898 | $4.9M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +7.4% | 124,341 | $4.8M |
| Citigroup Inc. | 0.00% | Add +64.7% | 121,022 | $4.7M |
| Hussman Strategic Advisors, Inc. | 1.20% | New | 105,000 | $4.1M |
| Opaleye Management Inc. | 0.72% | No change | 105,000 | $4.1M |
| Caption Management, LLC | 0.16% | Add +347.7% | 98,934 | $3.8M |
| Rafferty Asset Management, LLC | 0.01% | Add +6.2% | 95,467 | $3.7M |
| Trexquant Investment LP | 0.04% | Add +301.8% | 92,788 | $3.6M |
| Franklin Resources Inc. | 0.00% | Add +8.9% | 88,870 | $3.4M |
| Swiss National Bank | 0.00% | Add +1.2% | 86,900 | $3.4M |
| Silvercrest Asset Management Group LLC | 0.02% | Reduce -1.0% | 84,426 | $3.3M |
| Voya Investment Management LLC | 0.00% | Reduce -27.4% | 82,627 | $3.2M |
| Northwestern Mutual Wealth Management Co. | 0.00% | No change | 78,894 | $3.0M |
| Aquilo Capital Management, LLC | 5.06% | New | 76,592 | $3.0M |
| E Fund Management Co., Ltd. | 0.15% | Add +6.2% | 76,087 | $2.9M |
| Ikarian Capital, LLC | 0.77% | New | 70,000 | $2.7M |
| Susquehanna International Group, LLP | 0.00% | Add +73.3% | 69,937 | $2.7M |
| Superstring Capital Management LP | 2.34% | New | 68,892 | $2.7M |
| Alliancebernstein L.P. | 0.00% | Reduce -16.7% | 68,225 | $2.6M |
| Moody Aldrich Partners LLC | 0.48% | Reduce -43.5% | 67,415 | $2.6M |
| HighVista Strategies LLC | 0.90% | Reduce -30.1% | 62,518 | $2.4M |
| Great Lakes Advisors, LLC | 0.02% | Reduce -11.0% | 61,947 | $2.4M |
| Jane Street Group, LLC | 0.00% | Add +87.3% | 61,551 | $2.4M |
| Prudential Financial Inc. | 0.00% | Reduce -1.3% | 59,998 | $2.3M |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 56,536 | $2.2M |
| Alps Advisors Inc. | 0.01% | Add +7.5% | 55,941 | $2.2M |
| Knott David M Jr | 0.73% | No change | 52,368 | $2.0M |
| Assenagon Asset Management S.A. | 0.00% | New | 52,239 | $2.0M |
| State of Wisconsin Investment Board | 0.01% | Add +7.7% | 50,782 | $2.0M |
| Swedbank AB | 0.00% | No change | 50,000 | $1.9M |
| Birchview Capital, LP | 1.51% | No change | 48,000 | $1.9M |
| Thrivent Financial for Lutherans | 0.00% | Reduce -0.4% | 46,066 | $1.8M |
| California State Teachers Retirement System | 0.00% | Reduce -0.7% | 42,349 | $1.6M |
| Wells Fargo & Company | 0.00% | Add +32.1% | 38,796 | $1.5M |
| Quantedge Capital Pte Ltd | 0.52% | Add +12.8% | 37,200 | $1.4M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.4% | 37,055 | $1.4M |
| MetLife Investment Management, LLC | 0.01% | Add +5.9% | 35,798 | $1.4M |
| State of Alaska, Department of Revenue | 0.01% | Add +0.8% | 33,871 | $1.3M |
| Illinois Municipal Retirement Fund | 0.02% | Add +15.1% | 33,509 | $1.3M |
| Massachusetts Financial Services Co. | 0.00% | New | 32,449 | $1.3M |
| Hennion & Walsh Asset Management, Inc. | 0.06% | Reduce -14.3% | 32,074 | $1.2M |
| Intech Investment Management LLC | 0.01% | Add +64.6% | 31,480 | $1.2M |
| Los Angeles Capital Management LLC | 0.00% | Add +39.7% | 31,366 | $1.2M |
| Cavalier Investments, LLC | 0.40% | Add +4.3% | 31,252 | $1.2M |
| Corebridge Financial, Inc. | 0.01% | Reduce -7.2% | 31,155 | $1.2M |
| ExodusPoint Capital Management, LP | 0.01% | New | 29,870 | $1.2M |
| Louisiana State Employees Retirement System | 0.02% | Add +1.1% | 28,800 | $1.1M |
| Capital Fund Management S.A. | 0.01% | New | 28,058 | $1.1M |
| State of Tennessee, Department of Treasury | 0.00% | Reduce -2.4% | 27,076 | $1.0M |
| Ensign Peak Advisors, Inc | 0.00% | No change | 27,036 | $1.0M |
| WINTON GROUP Ltd | 0.07% | Add +3.0% | 26,768 | $1.0M |
| New York State Teachers Retirement System | 0.00% | No change | 24,592 | $949K |
| Sei Investments Co. | 0.00% | Reduce -30.0% | 24,568 | $948K |
| Bellevue Group AG | 0.02% | Add +92.1% | 23,718 | $916K |
| Summit Global Investments | 0.06% | New | 23,557 | $909K |
| STRS Ohio | 0.00% | Add +9.3% | 23,500 | $907K |
| Yousif Capital Management, LLC | 0.01% | Reduce -1.4% | 22,918 | $885K |
| Sierra Summit Advisors LLC | 0.17% | Add +5.3% | 22,282 | $860K |
| Janus Henderson Group PLC | 0.00% | No change | 21,454 | $828K |
| Mackenzie Financial Corp. | 0.00% | Add +174.6% | 21,349 | $824K |
| Tidal Investments LLC | 0.01% | Reduce -4.8% | 21,012 | $811K |
| Profund Advisors LLC | 0.03% | Add +2.8% | 20,649 | $797K |
| Comerica Bank | 0.00% | Reduce -1.7% | 20,558 | $794K |
| ProShare Advisors LLC | 0.00% | Add +30.5% | 20,457 | $790K |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 20,200 | $780K |
| Boothbay Fund Management, LLC | 0.02% | New | 20,188 | $779K |
| Maryland State Retirement & Pension System | 0.02% | Add +1.4% | 20,170 | $779K |
| Braidwell LP | 0.03% | New | 20,109 | $776K |
| Marshall Wace, LLP | 0.00% | Reduce -93.8% | 19,716 | $761K |
| BNP Paribas Financial Markets | 0.00% | Reduce -4.1% | 19,465 | $751K |
| Guggenheim Capital LLC | 0.01% | Add +141.6% | 19,078 | $736K |
| Mariner, LLC | 0.00% | Add +12.5% | 17,983 | $694K |
| New York State Common Retirement Fund | 0.00% | Reduce -11.4% | 17,882 | $690K |
| Algert Global LLC | 0.02% | Reduce -84.7% | 17,720 | $684K |
| Handelsbanken Fonder AB | 0.00% | New | 17,600 | $679K |
| Amalgamated Bank | 0.01% | Add +0.5% | 17,405 | $672K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 16,303 | $629K |
| Moran Wealth Management, LLC | 0.02% | Add +6.2% | 15,961 | $616K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 15,800 | $610K |
| Aviva PLC | 0.00% | New | 14,627 | $565K |
| Oregon Public Employees Retirement Fund | 0.01% | Add +0.7% | 14,000 | $540K |
| Erste Asset Management GmbH | 0.01% | New | 13,500 | $526K |
| Cerity Partners LLC | 0.00% | Reduce -8.3% | 13,056 | $518K |
| Teacher Retirement System of Texas | 0.00% | Add +18.7% | 13,099 | $506K |
| Arizona State Retirement System | 0.00% | Add +1.1% | 12,805 | $494K |
| Commonwealth of Pennsylvania Public School Empls Retrmt SYS | 0.00% | Add +1.1% | 12,723 | $491K |
| Crestline Management, L.P. | 0.02% | New | 12,681 | $489K |
| China Universal Asset Management Co., Ltd. | 0.05% | Add +11.6% | 12,637 | $488K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | — | 12,441 | $480K |
| Scientech Research LLC | 0.13% | Reduce -17.0% | 12,054 | $465K |
| Franklin Street Advisors Inc. | 0.03% | Reduce -0.9% | 11,300 | $436K |
| Allianz Asset Management GmbH | 0.00% | Reduce -43.0% | 11,000 | $425K |
| Cambria Investment Management, L.P. | 0.02% | New | 10,575 | $408K |
| Inspire Investing, LLC | 0.05% | Reduce -71.1% | 10,555 | $407K |
| Cache Advisors, LLC | 0.16% | — | 10,143 | $392K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -1.3% | 9,702 | $374K |
| Mutual of America Capital Management LLC | 0.00% | Add +1.9% | 9,027 | $348K |
| PEAK6 LLC | 0.01% | — | 9,000 | $347K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -29.7% | 8,981 | $347K |
| Glenmede Trust Co. NA | 0.00% | Reduce -40.2% | 8,953 | $346K |
| KLP Kapitalforvaltning As | 0.00% | — | 8,700 | $336K |
| HSBC Holdings PLC | 0.00% | Add +38.5% | 8,128 | $313K |
| HRT Financial LP | 0.00% | New | 8,025 | $309K |
| State of Wyoming | 0.04% | Add +11.9% | 7,832 | $302K |
| Royal Bank of Canada | 0.00% | Reduce -43.7% | 7,630 | $295K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +1946.9% | 7,369 | $284K |
| AlphaCentric Advisors LLC | 0.27% | Reduce -71.5% | 7,123 | $275K |
| XTX Topco Ltd | 0.02% | Reduce -54.4% | 6,744 | $260K |
| Freestone Grove Partners LP | 0.00% | — | 6,644 | $256K |
| Contravisory Investment Management, Inc. | 0.05% | New | 6,498 | $251K |
| Creative Planning | 0.00% | Reduce -14.1% | 6,448 | $249K |
| Bleakley Financial Group, LLC | 0.01% | Reduce -9.4% | 6,367 | $246K |
| Bank of Montreal | 0.00% | Add +4.5% | 6,250 | $241K |
| King Wealth Management Group | 0.03% | No change | 6,000 | $232K |
| Allspring Global Investments Holdings, LLC | 0.00% | Reduce -94.3% | 5,975 | $231K |
| Ameritas Investment Partners, Inc. | 0.01% | No change | 5,912 | $228K |
| Captrust Financial Advisors | 0.00% | Reduce -4.0% | 5,878 | $227K |
| Acadian Asset Management LLC | 0.00% | Add +146.7% | 5,889 | $226K |
| Caprock Group, LLC | 0.01% | New | 5,802 | $224K |
| Advantage Alpha Capital Partners LP | 0.05% | Reduce -49.4% | 5,742 | $222K |
| D. E. Shaw & Co. | 0.00% | Reduce -78.7% | 5,704 | $220K |
| Two Sigma Investments, LP | 0.00% | Reduce -0.9% | 5,658 | $218K |
| Kestra Advisory Services, LLC | 0.00% | Add +8.9% | 5,647 | $218K |
| Two Sigma Securities, LLC | 0.04% | New | 5,505 | $212K |
| Cibc World Markets Corp. | 0.00% | New | 5,468 | $211K |
| Simplex Trading, LLC | 0.01% | New | 5,487 | $211K |
| Cornerstone Investment Partners, LLC | 0.01% | Reduce -0.1% | 5,416 | $209K |
| Nisa Investment Advisors, LLC | 0.00% | Add +10.4% | 3,133 | $121K |
| New Vernon Capital Holdings II LLC | 0.08% | New | 3,061 | $118K |
| Advisors Asset Management, Inc. | 0.00% | New | 2,598 | $100K |
| AlphaQuest LLC | 0.01% | Reduce -90.9% | 2,177 | $84K |
| US Bancorp \de | 0.00% | Reduce -72.9% | 2,130 | $82K |
| KBC Group NV | 0.00% | Add +54.4% | 2,093 | $81K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -6.8% | 1,986 | $77K |
| Amundi | 0.00% | No change | 2,033 | $76K |
| Virtus Advisers, LLC | 0.03% | Reduce -34.3% | 1,761 | $68K |
| Covestor Ltd | 0.04% | Add +5200.0% | 1,643 | $63K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -16.7% | 1,441 | $56K |
| GF Fund Management Co. LTD. | 0.00% | — | 1,251 | $48K |
| Exchange Traded Concepts, LLC | 0.00% | Add +6.7% | 1,025 | $40K |
| FNY Investment Advisers, LLC | 0.02% | New | 1,000 | $38K |
| Osaic Holdings, Inc. | 0.00% | Add +232.6% | 592 | $23K |
| Smartleaf Asset Management LLC | 0.00% | Add +456.7% | 501 | $19K |
| GAMMA Investing LLC | 0.00% | Reduce -13.9% | 475 | $18K |
| Cwm, LLC | 0.00% | Reduce -69.7% | 386 | $15K |
| Global Retirement Partners, LLC | 0.00% | Reduce -12.6% | 304 | $12K |
| Assetmark, Inc. | 0.00% | Add +48.5% | 245 | $9K |
| Bessemer Group Inc. | 0.00% | Add +113.8% | 201 | $8K |
| Daiwa Securities Group Inc. | 0.00% | No change | 215 | $8K |
| UMB Bank, n.a. | 0.00% | No change | 163 | $6K |
| Truvestments Capital LLC | 0.00% | No change | 131 | $5K |
| Clearstead Advisors, LLC | 0.00% | No change | 110 | $4K |
| Danske Bank A/S | 0.00% | Reduce -75.0% | 100 | $4K |
| Fifth Third Bancorp | 0.00% | Reduce -10.7% | 92 | $4K |
| Harvest Fund Management Co., Ltd | 0.00% | Reduce -94.8% | 80 | $3K |
| CoreCap Advisors, LLC | 0.00% | Reduce -76.5% | 76 | $3K |
| Group One Trading LLC | 0.00% | New | 70 | $3K |
| Lindbrook Capital, LLC | 0.00% | Reduce -13.2% | 66 | $3K |
| Sterling Capital Management LLC | 0.00% | No change | 60 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +1600.0% | 51 | $2K |
| Rothschild Investment LLC | 0.00% | Reduce -10.0% | 45 | $2K |
| Farther Finance Advisors, LLC | 0.00% | No change | 44 | $2K |
| Wolff Wiese Magana LLC | 0.00% | No change | 35 | $1K |
| Farmers & Merchants Investments Inc. | 0.00% | New | 35 | $1K |
| Russell Investments Group, Ltd. | 0.00% | Add +20.8% | 29 | $1K |
| Parallel Advisors, LLC | 0.00% | Reduce -37.2% | 27 | $1K |
| Picton Mahoney Asset Management | 0.00% | No change | 25 | $1K |
| Arax Advisory Partners | 0.00% | New | 21 | $811 |
| Jones Financial Companies LLLP | 0.00% | New | 18 | $695 |
| Bell Investment Advisors, Inc | 0.00% | No change | 17 | $657 |
| Larson Financial Group LLC | 0.00% | Reduce -11.8% | 15 | $579 |
| Principal Securities, Inc. | 0.00% | Reduce -20.0% | 12 | $463 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 10 | $386 |
| Federated Hermes, Inc. | 0.00% | New | 7 | $270 |
| Huntington National Bank | 0.00% | New | 5 | $193 |
| IFP Advisors, Inc | 0.00% | New | 5 | $193 |
| Parkside Financial Bank & Trust | 0.00% | No change | 4 | $155 |
| Abound Wealth Management | 0.00% | Reduce -20.0% | 4 | $155 |
"% of holder's portfolio" is PTGX's weight in each manager's 13F, not the share of Protagonist Therapeutics Inc. the manager owns.