Rhythm PharmaceuticalsRYTM
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 203 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, up 27 from Q3 2024. 38 opened new positions and 24 sold out. The largest holders were BlackRock, Inc. ($389.1M), Primecap Management Co. ($367.9M) and Ra Capital Management, L.P. ($340.6M). 6 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Joel Greenblatt (0.0% of Gotham Asset Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Rhythm Pharmaceuticals Inc.
- CUSIP
- 76243J105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 38 | $67.2M |
| Exits | 24 | $138.9M |
All 13F filers, Q3 2024 → Q4 2024: 4,160,355 shares bought and 7,094,553 shares sold, net −2,934,198 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 203 holders
| BlackRock, Inc. | 0.01% | Add +0.9% | 6,950,715 | $389.1M |
| Primecap Management Co. | 0.28% | Reduce -8.9% | 6,571,190 | $367.9M |
| Ra Capital Management, L.P. | 4.54% | No change | 6,084,412 | $340.6M |
| Baker Bros. Advisors LP | 3.69% | Reduce -4.9% | 6,084,249 | $340.6M |
| Perceptive Advisors LLC | 5.74% | Add +3.4% | 3,680,473 | $206.0M |
| Vanguard Group Inc. | 0.00% | Reduce -0.1% | 3,442,600 | $192.7M |
| NEA Management Company, LLC | 9.19% | No change | 2,909,956 | $162.9M |
| Frazier Life Sciences Management, L.P. | 4.36% | Reduce -22.6% | 1,869,808 | $104.7M |
| State Street Corp. | 0.00% | Reduce -7.6% | 1,840,870 | $103.1M |
| Goldman Sachs Group Inc. | 0.02% | Reduce -53.3% | 1,812,206 | $101.4M |
| Federated Hermes, Inc. | 0.19% | Reduce -6.9% | 1,549,635 | $86.7M |
| Polar Capital Holdings Plc | 0.47% | No change | 1,500,000 | $84.0M |
| Driehaus Capital Management LLC | 0.60% | Reduce -0.7% | 1,290,975 | $72.3M |
| Geode Capital Management, LLC | 0.01% | Reduce -0.0% | 1,255,799 | $70.3M |
| Janus Henderson Group PLC | 0.03% | Add +103.9% | 1,219,554 | $68.3M |
| Alkeon Capital Management LLC | 0.38% | No change | 1,167,700 | $65.4M |
| Rock Springs Capital Management LP | 2.48% | Reduce -5.3% | 1,162,718 | $65.1M |
| Checkpoint Capital L.P. | 20.74% | Add +9.7% | 727,982 | $40.8M |
| Marshall Wace, LLP | 0.05% | Add +70.4% | 692,803 | $38.8M |
| T. Rowe Price Associates Inc. | 0.00% | Add +24.4% | 685,152 | $38.4M |
| Hood River Capital Management LLC | 0.53% | Add +4.7% | 643,691 | $36.0M |
| Loomis Sayles & Co. L P | 0.04% | Reduce -2.9% | 618,485 | $34.6M |
| Morgan Stanley | 0.00% | Add +20.6% | 560,087 | $31.4M |
| Northern Trust Corp. | 0.00% | Add +9.4% | 545,314 | $30.5M |
| Opaleye Management Inc. | 4.99% | No change | 500,000 | $28.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.5% | 440,250 | $24.6M |
| Cormorant Asset Management, LP | 1.23% | No change | 400,000 | $22.4M |
| Orbimed Advisors LLC | 0.46% | Reduce -8.2% | 400,000 | $22.4M |
| Sofinnova Investments, Inc. | 1.63% | Add +43.6% | 397,428 | $22.2M |
| Voloridge Investment Management, LLC | 0.08% | Add +7.7% | 380,537 | $21.3M |
| Pictet Asset Management Holding SA | 0.02% | Add +14.0% | 375,349 | $21.0M |
| Candriam S.C.A. | 0.11% | Reduce -15.9% | 332,392 | $18.6M |
| Invesco Ltd. | 0.00% | Add +14.5% | 302,846 | $17.0M |
| Silverarc Capital Management, LLC | 3.43% | Add +7.2% | 273,896 | $15.3M |
| Franklin Resources Inc. | 0.00% | Add +3.4% | 268,205 | $15.0M |
| JPMorgan Chase & Co. | 0.00% | Add +224.3% | 264,585 | $14.8M |
| UBS Group AG | 0.00% | Add +231.8% | 254,264 | $14.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -3.0% | 218,544 | $12.2M |
| Stempoint Capital LP | 2.92% | Add +404.1% | 208,016 | $11.6M |
| Norges Bank | 0.00% | Add +210.3% | 205,649 | $11.5M |
| Samsara Biocapital, LLC | 1.33% | No change | 172,647 | $9.7M |
| Lord, Abbett & Co. LLC | 0.03% | Add +56.5% | 160,651 | $9.0M |
| Integral Health Asset Management, LLC | 0.74% | New | 150,000 | $8.4M |
| Bank of New York Mellon Corp | 0.00% | Reduce -0.5% | 148,246 | $8.3M |
| Nuveen Asset Management, LLC | 0.00% | Reduce -0.7% | 146,903 | $8.2M |
| Walleye Capital LLC | 0.09% | New | 144,342 | $8.1M |
| Balyasny Asset Management L.P. | 0.02% | New | 138,363 | $7.7M |
| Barclays PLC | 0.00% | Add +27.3% | 135,397 | $7.6M |
| First Trust Advisors LP | 0.01% | Add +67.2% | 118,337 | $6.6M |
| FMR LLC | 0.00% | Add +124.9% | 113,109 | $6.3M |
| Lazard Asset Management LLC | 0.01% | New | 106,261 | $5.9M |
| Bank of America Corp. | 0.00% | Reduce -1.7% | 104,488 | $5.8M |
| Hennion & Walsh Asset Management, Inc. | 0.25% | Reduce -1.5% | 99,447 | $5.6M |
| Voya Investment Management LLC | 0.01% | Reduce -5.5% | 97,169 | $5.4M |
| Qube Research & Technologies Ltd | 0.01% | New | 95,235 | $5.3M |
| Swiss National Bank | 0.00% | Add +1.0% | 90,200 | $5.0M |
| BNP Paribas Financial Markets | 0.00% | Add +491.0% | 85,249 | $4.8M |
| Cinctive Capital Management LP | 0.25% | New | 82,755 | $4.6M |
| Rhumbline Advisers | 0.00% | Add +2.5% | 82,731 | $4.6M |
| Aberdeen Group plc | 0.01% | Reduce -28.6% | 80,517 | $4.5M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | — | 76,084 | $4.3M |
| Diadema Partners LP | 4.73% | — | 75,000 | $4.2M |
| Citigroup Inc. | 0.00% | Add +69.4% | 69,777 | $3.9M |
| Informed Momentum Co LLC | 0.50% | New | 63,078 | $3.5M |
| Alliancebernstein L.P. | 0.00% | Add +3.2% | 61,470 | $3.4M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +23.1% | 59,969 | $3.4M |
| Schonfeld Strategic Advisors LLC | 0.02% | Add +95.5% | 59,700 | $3.3M |
| Jane Street Group, LLC | 0.01% | Reduce -46.5% | 58,415 | $3.3M |
| Global IMC LLC | 0.57% | New | 56,936 | $3.2M |
| Ameriprise Financial Inc. | 0.00% | Add +27.4% | 53,367 | $3.0M |
| Legal & General Group Plc | 0.00% | Add +1.9% | 51,803 | $2.9M |
| Susquehanna International Group, LLP | 0.00% | Add +135.8% | 50,664 | $2.8M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -22.0% | 50,394 | $2.8M |
| Artia Global Partners LP | 1.13% | New | 50,000 | $2.8M |
| Alps Advisors Inc. | 0.02% | New | 49,700 | $2.8M |
| Nan Fung Group Holdings Ltd | 2.35% | No change | 49,120 | $2.7M |
| Deutsche Bank AG | 0.00% | Add +46.5% | 48,745 | $2.7M |
| Wedge Capital Management L L P | 0.05% | Reduce -0.9% | 48,411 | $2.7M |
| D. E. Shaw & Co. | 0.00% | Add +1022.5% | 48,198 | $2.7M |
| TD Asset Management Inc | 0.00% | Add +50.3% | 47,800 | $2.7M |
| PDT Partners, LLC | 0.22% | Add +279.0% | 43,583 | $2.4M |
| California State Teachers Retirement System | 0.00% | Reduce -0.9% | 43,533 | $2.4M |
| Algert Global LLC | 0.05% | Reduce -23.3% | 41,551 | $2.3M |
| Citadel Advisors | 0.00% | Reduce -60.7% | 40,419 | $2.3M |
| HighVista Strategies LLC | 0.78% | No change | 37,426 | $2.1M |
| Wells Fargo & Company | 0.00% | Add +26.6% | 37,324 | $2.1M |
| Principal Financial Group Inc. | 0.00% | Add +13.2% | 36,884 | $2.1M |
| State of New Jersey Common Pension Fund D | 0.01% | New | 35,004 | $2.0M |
| American Century Companies Inc. | 0.00% | New | 33,766 | $1.9M |
| Sei Investments Co. | 0.00% | Add +15.5% | 33,522 | $1.9M |
| MetLife Investment Management, LLC | 0.01% | Add +5.8% | 33,498 | $1.9M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +2.0% | 33,156 | $1.9M |
| State of Wisconsin Investment Board | 0.00% | Reduce -0.6% | 32,262 | $1.8M |
| ADAR1 Capital Management, LLC | 0.37% | New | 30,941 | $1.7M |
| Harbor Capital Advisors, Inc. | 0.07% | Reduce -26.9% | 30,252 | $1.7M |
| Intech Investment Management LLC | 0.02% | Add +126.8% | 28,092 | $1.6M |
| Corebridge Financial, Inc. | 0.01% | Reduce -7.0% | 27,220 | $1.5M |
| Wellington Management Group LLP | 0.00% | Reduce -7.8% | 25,555 | $1.4M |
| Crestline Management, L.P. | 0.05% | Add +31.9% | 25,062 | $1.4M |
| Bellevue Group AG | 0.03% | Add +50.3% | 23,596 | $1.3M |
| Fiduciary Trust Co | 0.01% | No change | 20,000 | $1.1M |
| Bryce Point Capital, LLC | 0.32% | — | 19,607 | $1.1M |
| Stifel Financial Corp. | 0.00% | Reduce -1.6% | 19,516 | $1.1M |
| Persistent Asset Partners Ltd | 0.93% | — | 18,312 | $1.1M |
| Engineers Gate Manager LP | 0.02% | New | 19,183 | $1.1M |
| Castleark Management LLC | 0.04% | Reduce -4.5% | 18,390 | $1.0M |
| ProShare Advisors LLC | 0.00% | Add +31.3% | 18,328 | $1.0M |
| Ensign Peak Advisors, Inc | 0.00% | No change | 17,659 | $989K |
| Victory Capital Management Inc. | 0.00% | Reduce -5.7% | 17,152 | $960K |
| Comerica Bank | 0.00% | Reduce -2.5% | 17,113 | $958K |
| Handelsbanken Fonder AB | 0.00% | Reduce -11.9% | 17,021 | $953K |
| New York State Common Retirement Fund | 0.00% | No change | 16,850 | $943K |
| HSBC Holdings PLC | 0.00% | New | 16,287 | $921K |
| STRS Ohio | 0.00% | Add +164.5% | 16,400 | $918K |
| Quantinno Capital Management LP | 0.01% | No change | 16,120 | $902K |
| AQR Capital Management | 0.00% | Reduce -51.7% | 15,857 | $888K |
| Millennium Management | 0.00% | Reduce -58.7% | 15,259 | $854K |
| Tudor Investment Corporation | 0.01% | New | 15,245 | $853K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 14,670 | $821K |
| Teacher Retirement System of Texas | 0.00% | Add +18.5% | 13,586 | $761K |
| Arizona State Retirement System | 0.00% | Add +0.9% | 13,287 | $744K |
| Two Sigma Advisers, LP | 0.00% | Add +2.3% | 13,100 | $733K |
| China Universal Asset Management Co., Ltd. | 0.07% | Add +10.8% | 13,031 | $729K |
| Exchange Traded Concepts, LLC | 0.01% | Reduce -17.8% | 12,375 | $693K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | — | 11,655 | $652K |
| Atom Investors LP | 0.08% | New | 11,605 | $650K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 11,578 | $648K |
| Profund Advisors LLC | 0.02% | Reduce -21.5% | 10,481 | $587K |
| Creative Planning | 0.00% | Add +19.0% | 10,224 | $572K |
| Cannon Financial Strategists, Inc. | 0.10% | New | 10,000 | $560K |
| KLP Kapitalforvaltning As | 0.00% | — | 9,300 | $521K |
| Aquatic Capital Management LLC | 0.01% | New | 9,223 | $516K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -0.7% | 9,034 | $506K |
| Verition Fund Management LLC | 0.00% | New | 8,037 | $450K |
| Trexquant Investment LP | 0.01% | New | 7,798 | $437K |
| XTX Topco Ltd | 0.04% | New | 7,605 | $426K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 7,600 | $425K |
| Advisors Asset Management, Inc. | 0.01% | New | 7,074 | $396K |
| Farringdon Capital, Ltd. | 0.16% | — | 6,854 | $384K |
| Gotham Asset Management | 0.00% | Reduce -28.4% | 6,786 | $380K |
| Jain Global LLC | 0.01% | — | 6,700 | $375K |
| Virtus Advisers, LLC | 0.14% | Reduce -15.4% | 6,280 | $352K |
| Allianz Asset Management GmbH | 0.00% | Add +48.8% | 6,100 | $341K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 6,089 | $341K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | New | 5,866 | $328K |
| Jasper Ridge Partners, L.P. | 0.01% | No change | 5,639 | $316K |
| Ameritas Investment Partners, Inc. | 0.01% | No change | 5,546 | $310K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 5,463 | $306K |
| JGP Global Gestao de Recursos Ltda. | 0.69% | Reduce -90.5% | 5,378 | $301K |
| Dark Forest Capital Management LP | 0.04% | New | 5,211 | $292K |
| Cibc World Markets Corp. | 0.00% | New | 5,123 | $287K |
| Bridgefront Capital, LLC | 0.09% | New | 4,604 | $258K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +1100.8% | 4,539 | $254K |
| Mariner, LLC | 0.00% | New | 4,525 | $254K |
| Mackenzie Financial Corp. | 0.00% | No change | 4,343 | $243K |
| Texas Treasury Safekeeping Trust Co. | 0.01% | No change | 4,230 | $237K |
| LPL Financial LLC | 0.00% | Reduce -50.9% | 4,175 | $234K |
| Prudential Financial Inc. | 0.00% | Reduce -2.4% | 4,155 | $234K |
| Xponance LLC | 0.00% | New | 4,168 | $233K |
| Raymond James Financial Inc. | 0.00% | — | 3,892 | $218K |
| Chicago Partners Investment Group LLC | 0.01% | Reduce -21.8% | 3,696 | $214K |
| Freestone Capital Holdings, LLC | 0.01% | New | 3,700 | $207K |
| Simplex Trading, LLC | 0.00% | New | 2,475 | $138K |
| KBC Group NV | 0.00% | Add +78.2% | 2,251 | $126K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -7.4% | 2,048 | $114K |
| Elevation Wealth Partners, LLC | 0.05% | No change | 1,971 | $110K |
| Amalgamated Bank | 0.00% | No change | 1,875 | $105K |
| Whittier Trust Co. | 0.00% | Reduce -12.0% | 1,760 | $99K |
| Cwm, LLC | 0.00% | Add +45.0% | 1,344 | $75K |
| GF Fund Management Co. LTD. | 0.00% | — | 1,290 | $72K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -98.1% | 1,285 | $72K |
| Royal Bank of Canada | 0.00% | Reduce -80.7% | 1,214 | $68K |
| Ascentis Wealth Management, LLC | 0.02% | No change | 1,206 | $68K |
| State of Wyoming | 0.01% | New | 1,084 | $61K |
| Natixis | 0.00% | Reduce -91.1% | 997 | $56K |
| Russell Investments Group, Ltd. | 0.00% | Add +0.3% | 997 | $56K |
| R Squared Ltd | 0.04% | — | 780 | $44K |
| Osaic Holdings, Inc. | 0.00% | Add +0.8% | 673 | $38K |
| SBI Securities Co., Ltd. | 0.00% | — | 666 | $37K |
| Raleigh Capital Management Inc. | 0.01% | New | 500 | $28K |
| Arax Advisory Partners | 0.00% | Add +740.7% | 454 | $25K |
| Ameriflex Group, Inc. | 0.01% | — | 360 | $21K |
| PNC Financial Services Group, Inc. | 0.00% | Add +147.2% | 304 | $17K |
| Jones Financial Companies LLLP | 0.00% | No change | 231 | $13K |
| Signaturefd, LLC | 0.00% | Add +4.2% | 222 | $12K |
| GAMMA Investing LLC | 0.00% | Add +66.1% | 201 | $11K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -10.6% | 203 | $11K |
| Smartleaf Asset Management LLC | 0.00% | Add +60.8% | 193 | $11K |
| US Bancorp \de | 0.00% | No change | 141 | $8K |
| Truvestments Capital LLC | 0.00% | No change | 138 | $8K |
| Lindbrook Capital, LLC | 0.00% | No change | 126 | $7K |
| Rothschild Investment LLC | 0.00% | Add +550.0% | 65 | $4K |
| Sterling Capital Management LLC | 0.00% | No change | 56 | $3K |
| Bessemer Group Inc. | 0.00% | No change | 30 | $2K |
| Parallel Advisors, LLC | 0.00% | No change | 19 | $1K |
| Covestor Ltd | 0.00% | Add +233.3% | 10 | $1K |
| Farther Finance Advisors, LLC | 0.00% | No change | 14 | $784 |
| CVA Family Office, LLC | 0.00% | No change | 12 | $672 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 12 | $672 |
| Whipplewood Advisors, LLC | 0.00% | — | 11 | $616 |
| Hexagon Capital Partners LLC | 0.00% | New | 7 | $392 |
| IFP Advisors, Inc | 0.00% | New | 1 | $56 |
| AlphaQuest LLC | 0.00% | Reduce -100.0% | 1 | $56 |
"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.