Xenon PharmaceuticalsXENE
13F holders, Q1 2025 (March 31)206holders −3
20new positions
22sold out
6famous investors
$33.58avg. 13F price*
At the end of Q1 2025, 206 institutions reported holding Xenon Pharmaceuticals Inc. (XENE) in their 13F filings, down 3 from Q4 2024. 20 opened new positions and 22 sold out. The largest holders were FMR LLC ($278.0M), Avoro Capital Advisors LLC ($192.6M) and Driehaus Capital Management LLC ($153.8M). 6 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Ron Baron (0.0% of Baron Capital (BAMCO)'s portfolio).
- Company
- Xenon Pharmaceuticals Inc.
- CUSIP
- 98420N105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 20 | $33.5M |
| Exits | 22 | $26.9M |
All 13F filers, Q4 2024 → Q1 2025: 6,629,185 shares bought and 6,216,567 shares sold, net +412,618 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 206 holders
| FMR LLC | 0.02% | Add +10.1% | 8,287,499 | $278.0M |
| Avoro Capital Advisors LLC | 3.01% | Add +1.3% | 5,741,666 | $192.6M |
| Driehaus Capital Management LLC | 1.48% | Add +1.4% | 4,584,859 | $153.8M |
| Wellington Management Group LLP | 0.02% | Add +0.3% | 3,789,197 | $127.1M |
| Janus Henderson Group PLC | 0.06% | Add +16.0% | 3,325,093 | $113.9M |
| Capital International Investors | 0.02% | Add +21.3% | 3,088,730 | $103.6M |
| Braidwell LP | 4.74% | Reduce -7.0% | 2,709,875 | $90.9M |
| Polar Capital Holdings Plc | 0.54% | Reduce -2.8% | 2,623,039 | $88.0M |
| Commodore Capital LP | 5.75% | Reduce -15.2% | 2,325,000 | $78.0M |
| Capital World Investors | 0.01% | Reduce -3.0% | 2,224,715 | $74.6M |
| BlackRock, Inc. | 0.00% | Reduce -3.3% | 2,036,125 | $68.3M |
| Adage Capital Partners Gp, L.L.C. | 0.12% | Add +2.8% | 1,914,749 | $64.2M |
| Pictet Asset Management Holding SA | 0.06% | Reduce -1.3% | 1,477,617 | $49.6M |
| Westfield Capital Management Co. LP | 0.23% | Add +20.2% | 1,391,370 | $46.7M |
| JPMorgan Chase & Co. | 0.00% | Add +0.1% | 1,357,602 | $45.5M |
| Alliancebernstein L.P. | 0.02% | Reduce -7.9% | 1,329,386 | $44.6M |
| Affinity Asset Advisors, LLC | 7.39% | Add +14.4% | 1,328,175 | $44.6M |
| Vestal Point Capital, LP | 3.11% | Add +60.5% | 1,300,000 | $43.6M |
| Samlyn Capital, LLC | 0.56% | Reduce -0.1% | 1,016,381 | $34.1M |
| Deep Track Capital, LP | 1.09% | Add +491.3% | 1,000,000 | $33.5M |
| Orbimed Advisors LLC | 0.76% | No change | 947,877 | $31.8M |
| Rock Springs Capital Management LP | 1.79% | Reduce -25.6% | 931,681 | $31.3M |
| T. Rowe Price Investment Management, Inc. | 0.02% | Reduce -44.6% | 796,986 | $26.7M |
| Jennison Associates LLC | 0.02% | Reduce -3.1% | 776,693 | $26.1M |
| Marshall Wace, LLP | 0.03% | Reduce -15.7% | 758,145 | $25.4M |
| TimesSquare Capital Management, LLC | 0.40% | Reduce -12.2% | 745,551 | $25.0M |
| Siren, L.L.C. | 1.39% | Reduce -1.5% | 732,761 | $24.6M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.06% | Add +6.0% | 703,795 | $23.6M |
| Citadel Advisors | 0.02% | Add +109.9% | 687,088 | $23.1M |
| First Turn Management, LLC | 4.62% | Reduce -0.2% | 683,451 | $22.9M |
| Loomis Sayles & Co. L P | 0.03% | Reduce -2.1% | 673,011 | $22.6M |
| Logos Global Management LP | 3.88% | New | 650,000 | $21.8M |
| First Light Asset Management, LLC | 2.41% | Reduce -45.9% | 627,904 | $21.1M |
| Boxer Capital Management, LLC | 6.06% | No change | 600,000 | $20.1M |
| Fiera Capital Corp | 0.06% | Reduce -1.2% | 529,442 | $17.8M |
| Franklin Resources Inc. | 0.00% | Reduce -14.7% | 491,120 | $16.5M |
| Candriam S.C.A. | 0.10% | Reduce -7.6% | 454,650 | $15.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +7.9% | 442,732 | $14.9M |
| Saturn V Capital Management LP | 7.00% | Add +28.3% | 413,711 | $13.9M |
| Aberdeen Group plc | 0.03% | Add +42.4% | 404,154 | $13.6M |
| Alyeska Investment Group, L.P. | 0.05% | Add +27.1% | 367,233 | $12.3M |
| Baker Bros. Advisors LP | 0.13% | Reduce -65.0% | 347,408 | $11.7M |
| Vanguard Group Inc. | 0.00% | Reduce -1.8% | 336,514 | $11.3M |
| Perceptive Advisors LLC | 0.39% | No change | 325,324 | $10.9M |
| State Street Corp. | 0.00% | Add +5.8% | 305,620 | $10.3M |
| MPM Bioimpact LLC | 1.75% | Add +53.8% | 303,398 | $10.2M |
| Two Sigma Advisers, LP | 0.02% | Add +0.0% | 298,800 | $10.0M |
| Stempoint Capital LP | 2.94% | Reduce -26.9% | 274,633 | $9.2M |
| DAFNA Capital Management LLC | 2.64% | No change | 273,739 | $9.2M |
| Balyasny Asset Management L.P. | 0.02% | Add +44.7% | 267,142 | $9.0M |
| Bank of New York Mellon Corp | 0.00% | Add +439.0% | 251,147 | $8.4M |
| Great Point Partners LLC | 4.47% | No change | 245,272 | $8.2M |
| Assenagon Asset Management S.A. | 0.01% | Add +1.1% | 241,206 | $8.1M |
| Two Sigma Investments, LP | 0.02% | Reduce -13.3% | 236,983 | $8.0M |
| Millennium Management | 0.01% | Reduce -32.4% | 234,056 | $7.9M |
| Federated Hermes, Inc. | 0.02% | Reduce -58.4% | 232,500 | $7.8M |
| DNB Asset Management AS | 0.04% | Add +12.9% | 229,482 | $7.7M |
| Avidity Partners Management LP | 1.58% | Reduce -51.7% | 229,000 | $7.7M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -17.4% | 214,860 | $7.2M |
| Point72 Asset Management | 0.02% | New | 209,759 | $7.0M |
| Invesco Ltd. | 0.00% | Reduce -1.8% | 205,763 | $6.9M |
| Granahan Investment Management, LLC | 0.31% | Add +0.8% | 183,808 | $6.2M |
| AXA S.A. | 0.02% | Reduce -6.6% | 175,350 | $5.9M |
| Parkman Healthcare Partners LLC | 0.69% | Reduce -9.6% | 174,576 | $5.9M |
| Nan Fung Group Holdings Ltd | 4.34% | Add +48.7% | 158,605 | $5.3M |
| Renaissance Technologies | 0.01% | Add +1029.2% | 154,700 | $5.2M |
| D. E. Shaw & Co. | 0.01% | Add +75.0% | 152,188 | $5.1M |
| Bridger Management, LLC | 2.45% | No change | 146,800 | $4.9M |
| New York State Common Retirement Fund | 0.01% | Add +7.4% | 142,372 | $4.8M |
| Schroder Investment Management Group | 0.00% | Reduce -22.3% | 137,221 | $4.7M |
| Bank of America Corp. | 0.00% | Add +27.8% | 136,569 | $4.6M |
| Morgan Stanley | 0.00% | Add +90.3% | 129,491 | $4.3M |
| ADAR1 Capital Management, LLC | 0.85% | Add +152.3% | 127,548 | $4.3M |
| Swiss National Bank | 0.00% | Reduce -0.8% | 125,600 | $4.2M |
| Algert Global LLC | 0.10% | Reduce -48.9% | 123,415 | $4.1M |
| UBS Group AG | 0.00% | Add +1471.0% | 105,333 | $3.5M |
| Ameriprise Financial Inc. | 0.00% | Add +12.2% | 103,624 | $3.5M |
| Baron Capital (BAMCO) | 0.01% | No change | 100,100 | $3.4M |
| State of Wisconsin Investment Board | 0.01% | Add +0.6% | 97,149 | $3.3M |
| PFM Health Sciences, LP | 0.24% | Reduce -21.2% | 92,236 | $3.1M |
| Lord, Abbett & Co. LLC | 0.01% | Reduce -54.9% | 87,981 | $3.0M |
| Nicholas Investment Partners, LP | 0.34% | Add +493.3% | 86,968 | $2.9M |
| Northern Trust Corp. | 0.00% | Add +23.2% | 81,024 | $2.7M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -64.7% | 75,341 | $2.5M |
| Ally Bridge Group (NY) LLC | 2.11% | Reduce -46.2% | 69,603 | $2.3M |
| Geode Capital Management, LLC | 0.00% | Add +0.1% | 69,597 | $2.3M |
| HighVista Strategies LLC | 0.86% | No change | 66,788 | $2.2M |
| Wells Fargo & Company | 0.00% | Add +10.7% | 65,912 | $2.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -66.9% | 63,568 | $2.1M |
| Raymond James Financial Inc. | 0.00% | Add +211.8% | 63,385 | $2.1M |
| Legal & General Group Plc | 0.00% | No change | 60,406 | $2.0M |
| Altium Capital Management LLC | 5.87% | Reduce -79.1% | 60,251 | $2.0M |
| Royal Bank of Canada | 0.00% | Reduce -1.2% | 59,366 | $2.0M |
| Harbor Capital Advisors, Inc. | 0.09% | Add +13.6% | 56,591 | $1.9M |
| California State Teachers Retirement System | 0.00% | No change | 55,492 | $1.9M |
| Alps Advisors Inc. | 0.01% | Reduce -10.3% | 55,332 | $1.9M |
| Moore Capital Management, LP | 0.07% | No change | 55,000 | $1.8M |
| Deutsche Bank AG | 0.00% | No change | 53,711 | $1.8M |
| Erste Asset Management GmbH | 0.02% | No change | 50,000 | $1.7M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -6.7% | 50,417 | $1.7M |
| Mutual of America Capital Management LLC | 0.02% | New | 48,763 | $1.6M |
| Voya Investment Management LLC | 0.00% | Reduce -23.0% | 48,065 | $1.6M |
| Skandinaviska Enskilda Banken AB (publ) | 0.01% | Add +17.5% | 47,457 | $1.6M |
| Nebula Research & Development LLC | 0.14% | Add +128.7% | 46,561 | $1.6M |
| Neuberger Berman Group LLC | 0.00% | Reduce -51.8% | 44,852 | $1.5M |
| Envestnet Asset Management Inc. | 0.00% | Reduce -9.4% | 42,850 | $1.4M |
| ExodusPoint Capital Management, LP | 0.02% | Reduce -39.0% | 42,000 | $1.4M |
| Artia Global Partners LP | 0.39% | No change | 40,000 | $1.3M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 39,000 | $1.3M |
| Prudential Financial Inc. | 0.00% | No change | 39,000 | $1.3M |
| Rhenman & Partners Asset Management AB | 0.14% | No change | 35,000 | $1.2M |
| TLS Advisors LLC | 2.50% | No change | 32,956 | $1.1M |
| J. Safra Sarasin Holding AG | 0.02% | Add +71.9% | 30,573 | $1.0M |
| Allostery Investments LP | 1.45% | No change | 30,000 | $1.0M |
| Sphera Funds Management LTD. | 0.22% | Reduce -49.9% | 26,097 | $876K |
| Ensign Peak Advisors, Inc | 0.00% | No change | 26,094 | $875K |
| NJ State Employees Deferred Compensation Plan | 0.11% | No change | 25,000 | $839K |
| Natixis Advisors, LLC | 0.00% | Add +1.9% | 24,010 | $806K |
| Atika Capital Management LLC | 0.12% | Reduce -66.9% | 24,000 | $805K |
| Rathbones Group PLC | 0.00% | No change | 23,666 | $794K |
| Schonfeld Strategic Advisors LLC | 0.01% | Add +51.5% | 22,954 | $770K |
| Handelsbanken Fonder AB | 0.00% | No change | 22,700 | $762K |
| CenterBook Partners LP | 0.05% | New | 22,211 | $745K |
| Birchview Capital, LP | 0.61% | Add +110.0% | 21,000 | $705K |
| Stifel Financial Corp. | 0.00% | Reduce -0.8% | 20,527 | $689K |
| Assetmark, Inc. | 0.00% | Reduce -7.7% | 19,934 | $669K |
| Sanders Morris Harris LLC | 0.10% | No change | 21,500 | $659K |
| Barclays PLC | 0.00% | Add +6.3% | 19,270 | $647K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -1.6% | 18,956 | $636K |
| Arizona State Retirement System | 0.00% | Reduce -0.5% | 18,579 | $623K |
| Prelude Capital Management, LLC | 0.06% | No change | 18,266 | $613K |
| Teacher Retirement System of Texas | 0.00% | Reduce -8.6% | 17,439 | $585K |
| BIT Capital GmbH | 0.07% | Reduce -67.8% | 17,352 | $582K |
| Occudo Quantitative Strategies LP | 0.08% | Add +48.4% | 16,975 | $582K |
| Cibc World Market Inc. | 0.00% | Reduce -17.6% | 16,335 | $548K |
| Knott David M Jr | 0.25% | Reduce -24.0% | 15,866 | $532K |
| Orion Porfolio Solutions, LLC | 0.01% | Add +15.6% | 15,531 | $521K |
| Orion Portfolio Solutions, LLC | 0.01% | Add +15.6% | 15,531 | $521K |
| China Universal Asset Management Co., Ltd. | 0.05% | Reduce -5.0% | 15,353 | $515K |
| Advisors Asset Management, Inc. | 0.01% | Add +9.4% | 14,281 | $479K |
| KLP Kapitalforvaltning As | 0.00% | No change | 12,800 | $429K |
| Verition Fund Management LLC | 0.00% | Add +50.8% | 12,508 | $420K |
| Y-Intercept (Hong Kong) Ltd | 0.03% | New | 11,949 | $401K |
| Fox Run Management, L.L.C. | 0.06% | Add +31.9% | 11,372 | $382K |
| Elmwood Wealth Management, Inc. | 0.15% | No change | 11,007 | $369K |
| Supplemental Annuity Collective Trust of NJ | 0.12% | No change | 11,000 | $369K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 10,633 | $357K |
| Aquatic Capital Management LLC | 0.01% | Add +27.3% | 10,511 | $353K |
| Silverarc Capital Management, LLC | 0.07% | New | 10,121 | $340K |
| Legato Capital Management LLC | 0.04% | New | 9,622 | $323K |
| Sei Investments Co. | 0.00% | New | 9,404 | $316K |
| Allianz Asset Management GmbH | 0.00% | Reduce -24.2% | 9,400 | $315K |
| EntryPoint Capital, LLC | 0.14% | New | 8,872 | $298K |
| SG Americas Securities, LLC | 0.00% | Reduce -34.9% | 8,655 | $290K |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -55.9% | 7,024 | $236K |
| Citigroup Inc. | 0.00% | Add +9.0% | 7,029 | $236K |
| Vident Advisory, LLC | 0.00% | Add +21.4% | 6,574 | $221K |
| Twinbeech Capital LP | 0.00% | New | 6,445 | $216K |
| Oxford Asset Management LLP | 0.10% | New | 6,174 | $207K |
| Tema ETFs LLC | 0.06% | No change | 6,111 | $205K |
| NEOS Investment Management LLC | 0.00% | No change | 6,111 | $205K |
| HighMark Wealth Management LLC | 0.12% | No change | 6,100 | $205K |
| Guggenheim Capital LLC | 0.00% | Reduce -2.6% | 6,019 | $202K |
| PNC Financial Services Group, Inc. | 0.00% | Add +1.6% | 5,220 | $175K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -0.4% | 5,000 | $168K |
| Virtus Investment Advisers, LLC | 0.04% | New | 4,161 | $140K |
| BNP Paribas Financial Markets | 0.00% | Reduce -3.7% | 3,210 | $108K |
| KBC Group NV | 0.00% | Add +0.7% | 2,761 | $93K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.8% | 2,561 | $88K |
| Quarry LP | 0.02% | No change | 2,000 | $67K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 1,952 | $65K |
| IFP Advisors, Inc | 0.00% | Reduce -1.9% | 1,921 | $65K |
| Caitong International Asset Management Co., Ltd | 0.02% | New | 905 | $30K |
| Parallel Advisors, LLC | 0.00% | Add +47.6% | 688 | $23K |
| Coldstream Capital Management Inc. | 0.00% | New | 648 | $22K |
| State of Wyoming | 0.00% | Add +5.5% | 574 | $19K |
| First Horizon Advisors, Inc. | 0.00% | No change | 370 | $12K |
| Point72 Hong Kong Ltd | 0.00% | New | 329 | $11K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 276 | $9K |
| US Bancorp \de | 0.00% | Reduce -53.1% | 275 | $9K |
| Blue Trust, Inc. | 0.00% | Add +8.9% | 270 | $9K |
| Daiwa Securities Group Inc. | 0.00% | No change | 252 | $8K |
| Cwm, LLC | 0.00% | Add +312.1% | 239 | $8K |
| National Bank of Canada | 0.00% | No change | 235 | $8K |
| Clearstead Advisors, LLC | 0.00% | No change | 218 | $7K |
| Spire Wealth Management | 0.00% | No change | 200 | $7K |
| Lindbrook Capital, LLC | 0.00% | Reduce -12.0% | 198 | $7K |
| Osaic Holdings, Inc. | 0.00% | Reduce -58.8% | 191 | $6K |
| Signaturefd, LLC | 0.00% | Reduce -67.6% | 185 | $6K |
| Amundi | 0.00% | Add +28.1% | 114 | $4K |
| J.Safra Asset Management Corp | 0.00% | Add +663.6% | 84 | $3K |
| Principal Securities, Inc. | 0.00% | No change | 58 | $2K |
| Point72 (DIFC) Ltd | 0.00% | New | 66 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +93.3% | 58 | $2K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -92.3% | 50 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | New | 39 | $1K |
| Whittier Trust Co. of Nevada Inc. | 0.00% | Reduce -2.7% | 36 | $1K |
| CVA Family Office, LLC | 0.00% | No change | 33 | $1K |
| CIBC Private Wealth Group LLC | 0.00% | New | 39 | $1K |
| Rhumbline Advisers | 0.00% | No change | 29 | $972 |
| Continuum Advisory, LLC | 0.00% | No change | 27 | $906 |
| Park Place Capital Corp | 0.00% | New | 16 | $537 |
| Allworth Financial LP | 0.00% | No change | 12 | $459 |
| Bell Investment Advisors, Inc | 0.00% | Reduce -88.9% | 11 | $370 |
| True Wealth Design, LLC | 0.00% | New | 9 | $302 |
| GAMMA Investing LLC | 0.00% | Reduce -84.3% | 8 | $268 |
"% of holder's portfolio" is XENE's weight in each manager's 13F, not the share of Xenon Pharmaceuticals Inc. the manager owns.