Denali TherapeuticsDNLI
13F holders, Q4 2024 (December 31)223holders +6
29new positions
28sold out
4famous investors
$20.38avg. 13F price*
At the end of Q4 2024, 223 institutions reported holding Denali Therapeutics Inc. (DNLI) in their 13F filings, up 6 from Q3 2024. 29 opened new positions and 28 sold out. The largest holders were BlackRock, Inc. ($283.7M), Baillie Gifford & Co. ($251.0M) and Vanguard Group Inc. ($245.0M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Denali Therapeutics Inc.
- CUSIP
- 24823R105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 29 | $26.8M |
| Exits | 28 | $17.1M |
All 13F filers, Q3 2024 → Q4 2024: 8,603,785 shares bought and 7,689,606 shares sold, net +914,179 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 223 holders
| BlackRock, Inc. | 0.01% | Add +1.0% | 13,920,245 | $283.7M |
| Baillie Gifford & Co. | 0.19% | Reduce -7.7% | 12,313,931 | $251.0M |
| Vanguard Group Inc. | 0.00% | Add +7.5% | 12,021,230 | $245.0M |
| Wellington Management Group LLP | 0.04% | Reduce -8.2% | 9,847,951 | $200.7M |
| FMR LLC | 0.01% | Add +2.4% | 8,019,746 | $163.4M |
| Capital Research Global Investors | 0.02% | Reduce -30.8% | 5,477,211 | $111.6M |
| Temasek Holdings (Private) Ltd | 0.43% | No change | 5,355,832 | $109.2M |
| State Street Corp. | 0.00% | Add +6.9% | 4,544,973 | $92.6M |
| Crestline Management, L.P. | 3.06% | Reduce -3.4% | 4,310,732 | $87.9M |
| Baker Bros. Advisors LP | 0.82% | No change | 3,731,695 | $76.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.02% | Reduce -4.4% | 3,582,874 | $73.0M |
| Alliancebernstein L.P. | 0.02% | Add +8.8% | 3,315,642 | $67.6M |
| T. Rowe Price Associates Inc. | 0.01% | Add +6.6% | 3,058,615 | $62.3M |
| Geode Capital Management, LLC | 0.00% | Reduce -0.7% | 2,935,283 | $59.8M |
| Camber Capital Management LP | 1.81% | Add +12.5% | 2,250,000 | $45.9M |
| Dimensional Fund Advisors LP | 0.01% | Add +19.0% | 1,855,036 | $37.8M |
| Marshall Wace, LLP | 0.05% | Reduce -9.1% | 1,788,737 | $36.5M |
| Bank of New York Mellon Corp | 0.00% | Reduce -6.6% | 1,242,987 | $25.3M |
| Morgan Stanley | 0.00% | Reduce -29.6% | 1,229,140 | $25.0M |
| Northern Trust Corp. | 0.00% | Add +10.7% | 1,201,518 | $24.5M |
| Principal Financial Group Inc. | 0.01% | Reduce -8.7% | 1,130,963 | $23.0M |
| Norges Bank | 0.00% | Add +168.1% | 1,065,608 | $21.7M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -22.7% | 1,057,523 | $21.6M |
| Artisan Partners Limited Partnership | 0.03% | Reduce -3.4% | 1,054,523 | $21.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.3% | 1,028,462 | $21.0M |
| Casdin Capital, LLC | 1.35% | No change | 990,000 | $20.2M |
| UBS Group AG | 0.00% | Add +503.1% | 852,861 | $17.4M |
| Siren, L.L.C. | 0.75% | No change | 834,028 | $17.0M |
| Candriam S.C.A. | 0.10% | Reduce -11.6% | 832,977 | $17.0M |
| Citadel Advisors | 0.02% | Add +6.8% | 829,911 | $16.9M |
| Fisher Asset Management | 0.01% | Add +44.8% | 792,499 | $16.2M |
| Yiheng Capital Management, L.P. | 3.16% | Add +16.7% | 700,098 | $14.3M |
| Cercano Management LLC | 0.32% | No change | 625,000 | $12.7M |
| Stempoint Capital LP | 2.99% | Add +107.2% | 584,328 | $11.9M |
| Polar Asset Management Partners Inc. | 0.22% | Add +1240.9% | 551,092 | $11.2M |
| Point72 Asset Management | 0.03% | Add +64.5% | 548,739 | $11.2M |
| American Century Companies Inc. | 0.01% | Add +6.5% | 480,529 | $9.8M |
| Balyasny Asset Management L.P. | 0.02% | Add +822.4% | 416,074 | $8.5M |
| Clarius Group, LLC | 0.57% | No change | 409,995 | $8.4M |
| Millennium Management | 0.01% | Add +571.8% | 404,224 | $8.2M |
| Aberdeen Group plc | 0.02% | Add +10.6% | 402,282 | $8.2M |
| Nuveen Asset Management, LLC | 0.00% | Reduce -50.4% | 355,057 | $7.2M |
| Ensign Peak Advisors, Inc | 0.01% | No change | 346,304 | $7.1M |
| Pier Capital, LLC | 0.97% | Add +97.7% | 332,319 | $6.8M |
| Qube Research & Technologies Ltd | 0.01% | New | 311,507 | $6.3M |
| AXA S.A. | 0.02% | Reduce -14.8% | 293,755 | $6.0M |
| Segall Bryant & Hamill, LLC | 0.08% | New | 289,075 | $5.9M |
| Barclays PLC | 0.00% | Add +8.7% | 278,067 | $5.7M |
| Deutsche Bank AG | 0.00% | Add +15.8% | 277,853 | $5.7M |
| Bank of America Corp. | 0.00% | Reduce -22.4% | 270,333 | $5.5M |
| TD Asset Management Inc | 0.00% | Add +8.7% | 265,752 | $5.4M |
| Twinbeech Capital LP | 0.09% | New | 254,586 | $5.2M |
| Swiss National Bank | 0.00% | Add +1.1% | 253,500 | $5.2M |
| Schroder Investment Management Group | 0.00% | Add +94.7% | 247,800 | $5.0M |
| Jane Street Group, LLC | 0.01% | Reduce -38.0% | 229,165 | $4.7M |
| JPMorgan Chase & Co. | 0.00% | Reduce -5.3% | 222,983 | $4.5M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +0.8% | 208,521 | $4.2M |
| Teachers Retirement System of the State of Kentucky | 0.04% | No change | 207,124 | $4.2M |
| Edmond DE Rothschild Holding S.A. | 0.07% | No change | 205,680 | $4.2M |
| Holocene Advisors, LP | 0.01% | Add +104.3% | 199,072 | $4.1M |
| Susquehanna Fundamental Investments, LLC | 0.07% | — | 192,563 | $3.9M |
| Rhumbline Advisers | 0.00% | Add +0.3% | 190,390 | $3.9M |
| Two Sigma Investments, LP | 0.01% | Add +80.8% | 179,884 | $3.7M |
| Citigroup Inc. | 0.00% | Add +76.0% | 166,706 | $3.4M |
| Legal & General Group Plc | 0.00% | Add +5.7% | 149,513 | $3.0M |
| New York State Common Retirement Fund | 0.00% | Reduce -3.5% | 144,724 | $2.9M |
| Rafferty Asset Management, LLC | 0.01% | Add +20.1% | 141,310 | $2.9M |
| Cinctive Capital Management LP | 0.14% | Reduce -12.5% | 130,445 | $2.7M |
| Invesco Ltd. | 0.00% | Reduce -41.1% | 121,478 | $2.5M |
| California State Teachers Retirement System | 0.00% | Reduce -0.8% | 120,174 | $2.4M |
| Alps Advisors Inc. | 0.01% | Add +9.5% | 116,377 | $2.4M |
| Prudential Financial Inc. | 0.00% | Reduce -5.8% | 110,593 | $2.3M |
| Groupama Asset Managment | 0.05% | Add +41.2% | 110,207 | $2.2M |
| Woodline Partners LP | 0.01% | New | 100,000 | $2.0M |
| State of Wisconsin Investment Board | 0.00% | Add +14.3% | 93,094 | $1.9M |
| Thrivent Financial for Lutherans | 0.00% | Reduce -33.0% | 92,972 | $1.9M |
| Hudson Bay Capital Management LP | 0.01% | Add +168.1% | 92,500 | $1.9M |
| Fred Alger Management, LLC | 0.01% | Reduce -24.3% | 91,807 | $1.9M |
| Wells Fargo & Company | 0.00% | Reduce -5.1% | 88,933 | $1.8M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +11.3% | 86,243 | $1.8M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.2% | 85,075 | $1.7M |
| MetLife Investment Management, LLC | 0.01% | Add +5.9% | 76,050 | $1.5M |
| Franklin Resources Inc. | 0.00% | Reduce -6.5% | 74,862 | $1.5M |
| Susquehanna International Group, LLP | 0.00% | Add +42.0% | 71,240 | $1.5M |
| Nisa Investment Advisors, LLC | 0.01% | Add +0.2% | 66,621 | $1.4M |
| First Trust Advisors LP | 0.00% | Add +260.9% | 65,442 | $1.3M |
| Corebridge Financial, Inc. | 0.01% | Reduce -7.0% | 61,800 | $1.3M |
| Trexquant Investment LP | 0.01% | Add +147.2% | 60,656 | $1.2M |
| Janus Henderson Group PLC | 0.00% | Add +15.2% | 60,028 | $1.2M |
| Diadema Partners LP | 1.38% | — | 60,000 | $1.2M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 59,800 | $1.2M |
| Voya Investment Management LLC | 0.00% | Reduce -5.2% | 54,813 | $1.1M |
| Engineers Gate Manager LP | 0.02% | New | 53,358 | $1.1M |
| Squarepoint Ops LLC | 0.00% | Add +44.2% | 48,619 | $991K |
| Guggenheim Capital LLC | 0.01% | Add +133.5% | 48,131 | $981K |
| Creative Planning | 0.00% | Reduce -20.4% | 47,950 | $977K |
| Intech Investment Management LLC | 0.01% | Add +60.5% | 47,401 | $966K |
| MAI Capital Management | 0.01% | New | 46,526 | $948K |
| Pier 88 Investment Partners LLC | 1.13% | Reduce -23.3% | 45,410 | $925K |
| ADAR1 Capital Management, LLC | 0.19% | Reduce -56.0% | 44,826 | $914K |
| Employees Retirement System of Texas | 0.01% | No change | 43,769 | $892K |
| Skandinaviska Enskilda Banken AB (publ) | 0.00% | No change | 43,245 | $875K |
| ProShare Advisors LLC | 0.00% | Add +30.9% | 41,825 | $852K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +33.8% | 39,757 | $810K |
| Knights of Columbus Asset Advisors LLC | 0.05% | Add +0.3% | 39,217 | $799K |
| Algert Global LLC | 0.02% | Reduce -19.8% | 39,015 | $795K |
| Fox Run Management, L.L.C. | 0.14% | New | 38,668 | $788K |
| Victory Capital Management Inc. | 0.00% | Reduce -3.5% | 38,508 | $785K |
| Handelsbanken Fonder AB | 0.00% | Reduce -3.0% | 38,300 | $781K |
| Teacher Retirement System of Texas | 0.00% | Add +18.6% | 38,178 | $778K |
| Campbell & CO Investment Adviser LLC | 0.06% | New | 37,685 | $768K |
| Envestnet Asset Management Inc. | 0.00% | Add +34.5% | 37,622 | $767K |
| Arizona State Retirement System | 0.00% | Add +1.2% | 37,395 | $762K |
| Ironwood Investment Management LLC | 0.37% | Reduce -0.1% | 36,546 | $745K |
| Y-Intercept (Hong Kong) Ltd | 0.05% | Add +160.5% | 36,006 | $734K |
| Dana Investment Advisors, Inc. | 0.02% | Reduce -1.6% | 34,302 | $699K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 34,168 | $696K |
| HSBC Holdings PLC | 0.00% | Add +24.2% | 33,390 | $680K |
| China Universal Asset Management Co., Ltd. | 0.06% | Add +10.8% | 30,517 | $622K |
| Profund Advisors LLC | 0.02% | Add +15.6% | 28,735 | $586K |
| Erste Asset Management GmbH | 0.01% | No change | 26,900 | $554K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | — | 26,479 | $540K |
| Raymond James Financial Inc. | 0.00% | — | 26,143 | $533K |
| HighTower Advisors, LLC | 0.00% | Reduce -30.0% | 26,138 | $533K |
| KLP Kapitalforvaltning As | 0.00% | — | 26,100 | $532K |
| Walleye Capital LLC | 0.01% | New | 24,820 | $506K |
| Sei Investments Co. | 0.00% | Reduce -8.5% | 24,047 | $490K |
| STRS Ohio | 0.00% | Add +36.8% | 23,800 | $485K |
| Cetera Investment Advisers | 0.00% | Add +1.8% | 22,700 | $463K |
| Verition Fund Management LLC | 0.00% | New | 22,601 | $461K |
| Man Group plc | 0.00% | Reduce -26.3% | 22,435 | $457K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -20.5% | 22,222 | $453K |
| Russell Investments Group, Ltd. | 0.00% | Add +0.7% | 22,116 | $451K |
| Pathstone Holdings, LLC | 0.00% | New | 21,224 | $433K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.01% | Reduce -31.6% | 21,039 | $429K |
| BIT Capital GmbH | 0.04% | Reduce -29.4% | 21,011 | $428K |
| Graham Capital Management, L.P. | 0.02% | Add +76.0% | 20,706 | $422K |
| Bryce Point Capital, LLC | 0.12% | — | 20,550 | $419K |
| Caption Management, LLC | 0.02% | New | 19,900 | $406K |
| Pictet Asset Management Holding SA | 0.00% | Add +16.9% | 19,356 | $394K |
| Bayesian Capital Management, LP | 0.05% | Add +135.3% | 18,820 | $384K |
| Empowered Funds, LLC | 0.01% | New | 18,587 | $379K |
| Brevan Howard Capital Management LP | 0.01% | Add +60.5% | 17,917 | $365K |
| Royal Bank of Canada | 0.00% | Reduce -20.1% | 17,511 | $357K |
| Ameriprise Financial Inc. | 0.00% | Add +126.3% | 16,743 | $341K |
| XTX Topco Ltd | 0.03% | New | 16,087 | $328K |
| BNP Paribas Financial Markets | 0.00% | Reduce -42.3% | 15,943 | $325K |
| Bellevue Group AG | 0.01% | No change | 15,700 | $320K |
| Aquatic Capital Management LLC | 0.01% | New | 15,694 | $320K |
| VELA Investment Management, LLC | 0.11% | No change | 15,635 | $319K |
| Two Sigma Advisers, LP | 0.00% | New | 15,100 | $308K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 13,434 | $274K |
| Dark Forest Capital Management LP | 0.04% | New | 12,888 | $263K |
| Ameritas Investment Partners, Inc. | 0.01% | No change | 12,592 | $257K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 12,238 | $249K |
| Cibc World Markets Corp. | 0.00% | New | 11,633 | $237K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -11.7% | 11,377 | $232K |
| Pitcairn Co. | 0.01% | Add +0.3% | 11,298 | $230K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +2519.0% | 11,288 | $230K |
| SG Americas Securities, LLC | 0.00% | Add +128.8% | 11,003 | $224K |
| Moneco Advisors, LLC | 0.02% | Add +16.5% | 10,600 | $216K |
| E Fund Management Co., Ltd. | 0.01% | Add +32.2% | 9,997 | $204K |
| Point72 (DIFC) Ltd | 0.01% | Add +13423.6% | 7,438 | $152K |
| AlphaQuest LLC | 0.02% | Add +177.1% | 6,961 | $142K |
| KBC Group NV | 0.00% | Add +75.8% | 6,334 | $129K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -7.4% | 4,796 | $99K |
| Amalgamated Bank | 0.00% | No change | 4,192 | $85K |
| PNC Financial Services Group, Inc. | 0.00% | Add +30.5% | 3,790 | $77K |
| Assetmark, Inc. | 0.00% | Reduce -3.4% | 3,679 | $75K |
| Point72 Hong Kong Ltd | 0.00% | New | 3,175 | $65K |
| Virtus Advisers, LLC | 0.03% | Reduce -27.3% | 3,029 | $62K |
| GF Fund Management Co. LTD. | 0.00% | — | 3,022 | $62K |
| Cwm, LLC | 0.00% | Add +11.6% | 2,402 | $49K |
| GAMMA Investing LLC | 0.00% | Reduce -3.9% | 2,248 | $46K |
| Sterling Capital Management LLC | 0.00% | Add +589.9% | 1,773 | $36K |
| Osaic Holdings, Inc. | 0.00% | Add +22.8% | 1,593 | $32K |
| Bartlett & Co. Wealth Management LLC | 0.00% | No change | 1,500 | $31K |
| Comerica Bank | 0.00% | Add +0.6% | 1,095 | $22K |
| Smartleaf Asset Management LLC | 0.00% | Add +59.9% | 1,065 | $22K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 1,001 | $21K |
| US Bancorp \de | 0.00% | Reduce -13.3% | 1,013 | $21K |
| Nemes Rush Group LLC | 0.00% | No change | 700 | $14K |
| Signaturefd, LLC | 0.00% | Add +6.9% | 603 | $12K |
| Huntington National Bank | 0.00% | Add +25.9% | 593 | $12K |
| Covestor Ltd | 0.01% | Add +0.2% | 579 | $12K |
| R Squared Ltd | 0.01% | — | 580 | $12K |
| Caitong International Asset Management Co., Ltd | 0.01% | — | 560 | $11K |
| Oarsman Capital, Inc. | 0.00% | No change | 500 | $10K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -13.0% | 475 | $10K |
| UMB Bank, n.a. | 0.00% | No change | 382 | $8K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -6.6% | 296 | $6K |
| Private Wealth Management Group, LLC | 0.00% | No change | 260 | $5K |
| Lindbrook Capital, LLC | 0.00% | Reduce -9.9% | 255 | $5K |
| City State Bank | 0.00% | No change | 250 | $5K |
| Versant Capital Management, Inc | 0.00% | No change | 203 | $4K |
| Brooklyn Investment Group | 0.00% | New | 172 | $4K |
| Meeder Asset Management Inc. | 0.00% | Add +3.8% | 165 | $3K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 154 | $3K |
| Activest Wealth Management | 0.00% | No change | 131 | $3K |
| Arax Advisory Partners | 0.00% | No change | 117 | $2K |
| Your Advocates Ltd., LLP | 0.00% | No change | 100 | $2K |
| Rothschild Investment LLC | 0.00% | Reduce -33.3% | 100 | $2K |
| Parallel Advisors, LLC | 0.00% | Reduce -11.6% | 99 | $2K |
| Bessemer Group Inc. | 0.00% | No change | 110 | $2K |
| Sherman Asset Management, Inc. | 0.00% | — | 94 | $2K |
| Amundi | 0.00% | New | 85 | $2K |
| Denver PWM, LLC | 0.00% | New | 80 | $2K |
| Bell Investment Advisors, Inc | 0.00% | No change | 52 | $1K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -67.3% | 35 | $713 |
| CVA Family Office, LLC | 0.00% | No change | 30 | $611 |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 25 | $510 |
| First Horizon Advisors, Inc. | 0.00% | No change | 25 | $509 |
| Cassady Schiller Wealth Management, LLC | 0.00% | New | 18 | $367 |
| Principal Securities, Inc. | 0.00% | Reduce -39.1% | 14 | $285 |
| Hexagon Capital Partners LLC | 0.00% | New | 12 | $245 |
| Allworth Financial LP | 0.00% | New | 10 | $234 |
| WealthTrak Capital Management LLC | 0.00% | — | 10 | $204 |
| National Bank of Canada | 0.00% | Reduce -79.4% | 7 | $143 |
| SBI Securities Co., Ltd. | 0.00% | — | 5 | $102 |
| Global Retirement Partners, LLC | 0.00% | No change | 3 | $61 |
| Global Financial Private Client, LLC | 0.00% | New | 2 | $41 |
| IFP Advisors, Inc | 0.00% | New | 1 | $20 |
| Hemington Wealth Management | 0.00% | Add +266.7% | 11 | $0 |
"% of holder's portfolio" is DNLI's weight in each manager's 13F, not the share of Denali Therapeutics Inc. the manager owns.