Denali TherapeuticsDNLI
13F holders, Q1 2025 (March 31)222holders −1
33new positions
34sold out
6famous investors
$13.60avg. 13F price*
At the end of Q1 2025, 222 institutions reported holding Denali Therapeutics Inc. (DNLI) in their 13F filings, down 1 from Q4 2024. 33 opened new positions and 34 sold out. The largest holders were BlackRock, Inc. ($188.1M), Baillie Gifford & Co. ($164.4M) and Vanguard Group Inc. ($160.4M). 6 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Denali Therapeutics Inc.
- CUSIP
- 24823R105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 33 | $21.2M |
| Exits | 34 | $31.9M |
All 13F filers, Q4 2024 → Q1 2025: 15,957,693 shares bought and 7,933,145 shares sold, net +8,024,548 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 222 holders
| BlackRock, Inc. | 0.00% | Reduce -0.6% | 13,834,956 | $188.1M |
| Baillie Gifford & Co. | 0.14% | Reduce -1.8% | 12,090,040 | $164.4M |
| Vanguard Group Inc. | 0.00% | Reduce -1.8% | 11,799,757 | $160.4M |
| Wellington Management Group LLP | 0.03% | Add +15.9% | 11,409,598 | $155.1M |
| FMR LLC | 0.01% | Reduce -7.6% | 7,413,354 | $100.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.02% | Add +88.9% | 6,766,916 | $92.0M |
| Temasek Holdings (Private) Ltd | 0.29% | No change | 5,355,832 | $72.8M |
| Capital Research Global Investors | 0.01% | Reduce -13.0% | 4,765,137 | $64.8M |
| State Street Corp. | 0.00% | Reduce -1.9% | 4,460,757 | $60.6M |
| T. Rowe Price Associates Inc. | 0.01% | Add +42.8% | 4,367,234 | $59.4M |
| Crestline Management, L.P. | 89.45% | Reduce -3.5% | 4,160,732 | $56.6M |
| Baker Bros. Advisors LP | 0.57% | No change | 3,731,695 | $50.7M |
| Alliancebernstein L.P. | 0.02% | Reduce -4.9% | 3,154,387 | $42.9M |
| Norges Bank | 0.01% | Add +186.0% | 3,047,606 | $41.4M |
| Geode Capital Management, LLC | 0.00% | Add +3.5% | 3,037,176 | $41.3M |
| Marshall Wace, LLP | 0.04% | Add +22.3% | 2,188,422 | $29.8M |
| Dimensional Fund Advisors LP | 0.01% | Add +13.3% | 2,100,856 | $28.6M |
| Goldman Sachs Group Inc. | 0.00% | Add +58.1% | 1,672,078 | $22.7M |
| Millennium Management | 0.02% | Add +269.4% | 1,493,068 | $20.3M |
| Fisher Asset Management | 0.01% | Add +72.2% | 1,364,959 | $18.6M |
| Morgan Stanley | 0.00% | Add +2.0% | 1,253,603 | $17.0M |
| Camber Capital Management LP | 1.06% | Reduce -44.4% | 1,250,000 | $17.0M |
| Citadel Advisors | 0.02% | Add +40.9% | 1,169,683 | $15.9M |
| Northern Trust Corp. | 0.00% | Reduce -5.8% | 1,132,173 | $15.4M |
| Bank of New York Mellon Corp | 0.00% | Reduce -11.2% | 1,103,892 | $15.0M |
| Principal Financial Group Inc. | 0.01% | Reduce -4.4% | 1,081,578 | $14.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -1.8% | 1,009,896 | $13.7M |
| Casdin Capital, LLC | 1.10% | No change | 990,000 | $13.5M |
| Candriam S.C.A. | 0.07% | Add +3.0% | 858,162 | $11.7M |
| Siren, L.L.C. | 0.63% | Reduce -1.5% | 821,513 | $11.2M |
| UBS Group AG | 0.00% | Reduce -7.5% | 788,429 | $10.7M |
| Aberdeen Group plc | 0.02% | Add +88.9% | 759,815 | $10.3M |
| Squarepoint Ops LLC | 0.02% | Add +1313.3% | 687,151 | $9.3M |
| Stempoint Capital LP | 2.90% | Add +14.2% | 667,078 | $9.1M |
| Cercano Management LLC | 0.25% | No change | 625,000 | $8.5M |
| Artisan Partners Limited Partnership | 0.01% | Reduce -41.9% | 612,438 | $8.3M |
| Ensign Peak Advisors, Inc | 0.02% | Add +69.7% | 587,785 | $8.0M |
| Yiheng Capital Management, L.P. | 2.25% | Reduce -32.9% | 469,981 | $6.4M |
| Bank of America Corp. | 0.00% | Add +65.6% | 447,757 | $6.1M |
| Pictet Asset Management Holding SA | 0.01% | Add +1677.0% | 343,959 | $5.1M |
| Clarius Group, LLC | 0.32% | Reduce -10.0% | 368,995 | $5.0M |
| American Century Companies Inc. | 0.00% | Reduce -27.3% | 349,420 | $4.8M |
| Pier Capital, LLC | 0.76% | Add +1.0% | 335,504 | $4.6M |
| Nuveen, LLC | 0.00% | — | 322,945 | $4.4M |
| Schroder Investment Management Group | 0.00% | Add +17.8% | 291,795 | $4.3M |
| TD Asset Management Inc | 0.00% | Add +16.1% | 308,580 | $4.2M |
| Voloridge Investment Management, LLC | 0.02% | New | 301,973 | $4.1M |
| AXA S.A. | 0.01% | Reduce -0.1% | 293,381 | $4.0M |
| Qube Research & Technologies Ltd | 0.01% | Reduce -7.5% | 288,221 | $3.9M |
| Segall Bryant & Hamill, LLC | 0.06% | Reduce -2.8% | 281,139 | $3.8M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +23.8% | 258,132 | $3.5M |
| Swiss National Bank | 0.00% | Reduce -1.0% | 250,900 | $3.4M |
| Boxer Capital Management, LLC | 1.02% | New | 250,000 | $3.4M |
| Hudson Bay Capital Management LP | 0.02% | Add +170.3% | 250,000 | $3.4M |
| Barclays PLC | 0.00% | Reduce -13.5% | 240,648 | $3.3M |
| Jane Street Group, LLC | 0.01% | Reduce -6.8% | 213,673 | $2.9M |
| Edmond DE Rothschild Holding S.A. | 0.05% | No change | 205,680 | $2.8M |
| SCS Capital Management LLC | 0.03% | New | 197,998 | $2.7M |
| Citigroup Inc. | 0.00% | Add +16.4% | 194,004 | $2.6M |
| Rhumbline Advisers | 0.00% | Reduce -0.1% | 190,256 | $2.6M |
| Invesco Ltd. | 0.00% | Add +55.9% | 189,427 | $2.6M |
| JPMorgan Chase & Co. | 0.00% | Reduce -15.5% | 188,403 | $2.6M |
| Teachers Retirement System of the State of Kentucky | 0.02% | Reduce -11.5% | 183,392 | $2.5M |
| Renaissance Technologies | 0.00% | New | 173,100 | $2.4M |
| Man Group plc | 0.01% | Add +655.0% | 169,385 | $2.3M |
| Susquehanna International Group, LLP | 0.00% | Add +134.7% | 167,197 | $2.3M |
| Groupama Asset Managment | 0.04% | Add +31.1% | 144,488 | $2.1M |
| Deutsche Bank AG | 0.00% | Reduce -43.8% | 156,252 | $2.1M |
| Legal & General Group Plc | 0.00% | Add +1.6% | 151,962 | $2.1M |
| Soleus Capital Management, L.P. | 0.14% | New | 135,000 | $1.8M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -8.6% | 129,135 | $1.8M |
| DAFNA Capital Management LLC | 0.50% | New | 127,900 | $1.7M |
| California State Teachers Retirement System | 0.00% | Reduce -2.2% | 117,535 | $1.6M |
| Woodline Partners LP | 0.01% | Add +13.5% | 113,517 | $1.5M |
| Trexquant Investment LP | 0.02% | Add +86.7% | 113,224 | $1.5M |
| Alps Advisors Inc. | 0.01% | Reduce -4.3% | 111,375 | $1.5M |
| Two Sigma Investments, LP | 0.00% | Reduce -43.1% | 102,403 | $1.4M |
| Rhenman & Partners Asset Management AB | 0.16% | New | 100,000 | $1.4M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +8.5% | 93,590 | $1.3M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.0% | 88,507 | $1.2M |
| Franklin Resources Inc. | 0.00% | Add +11.2% | 83,248 | $1.1M |
| Dark Forest Capital Management LP | 0.05% | Add +527.1% | 80,820 | $1.1M |
| State of Wisconsin Investment Board | 0.00% | Reduce -14.2% | 79,891 | $1.1M |
| D. E. Shaw & Co. | 0.00% | New | 78,218 | $1.1M |
| Intech Investment Management LLC | 0.01% | Add +63.7% | 77,590 | $1.1M |
| Wells Fargo & Company | 0.00% | Reduce -13.1% | 77,282 | $1.1M |
| MetLife Investment Management, LLC | 0.01% | Reduce -1.7% | 74,765 | $1.0M |
| Tudor Investment Corporation | 0.01% | New | 72,597 | $987K |
| Twinbeech Capital LP | 0.02% | Reduce -71.7% | 72,022 | $979K |
| New York State Common Retirement Fund | 0.00% | Reduce -51.5% | 70,240 | $955K |
| DekaBank Deutsche Girozentrale | 0.00% | Add +7.4% | 64,210 | $935K |
| Campbell & CO Investment Adviser LLC | 0.07% | Add +80.9% | 68,185 | $927K |
| Thrivent Financial for Lutherans | 0.00% | Reduce -26.9% | 67,917 | $924K |
| Janus Henderson Group PLC | 0.00% | No change | 60,028 | $888K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 60,898 | $828K |
| HSBC Holdings PLC | 0.00% | Add +73.7% | 58,003 | $779K |
| Guggenheim Capital LLC | 0.01% | Add +16.4% | 56,012 | $762K |
| Y-Intercept (Hong Kong) Ltd | 0.05% | Add +52.2% | 54,813 | $745K |
| Voya Investment Management LLC | 0.00% | Reduce -6.9% | 51,011 | $693K |
| Ironwood Investment Management LLC | 0.37% | Add +34.9% | 49,305 | $670K |
| SG Americas Securities, LLC | 0.00% | Add +339.6% | 48,365 | $658K |
| MAI Capital Management | 0.00% | No change | 46,526 | $633K |
| Pier 88 Investment Partners LLC | 0.73% | Reduce -1.1% | 44,910 | $611K |
| Walleye Capital LLC | 0.01% | Add +77.8% | 44,138 | $600K |
| Employees Retirement System of Texas | 0.01% | No change | 43,769 | $595K |
| Skandinaviska Enskilda Banken AB (publ) | 0.00% | No change | 43,245 | $588K |
| Graham Capital Management, L.P. | 0.03% | Add +107.7% | 43,005 | $585K |
| Victory Capital Management Inc. | 0.00% | Add +8.1% | 41,627 | $566K |
| Knights of Columbus Asset Advisors LLC | 0.04% | Add +2.7% | 40,275 | $548K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 39,757 | $540K |
| Prudential Financial Inc. | 0.00% | Reduce -65.1% | 38,643 | $525K |
| Handelsbanken Fonder AB | 0.00% | No change | 38,300 | $521K |
| Pathstone Holdings, LLC | 0.00% | Add +80.5% | 38,305 | $521K |
| Arizona State Retirement System | 0.00% | Reduce -0.8% | 37,112 | $505K |
| Two Sigma Advisers, LP | 0.00% | Add +133.8% | 35,300 | $480K |
| Teacher Retirement System of Texas | 0.00% | Reduce -8.7% | 34,857 | $474K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 34,168 | $465K |
| ProShare Advisors LLC | 0.00% | Reduce -20.0% | 33,461 | $455K |
| Dana Investment Advisors, Inc. | 0.02% | Reduce -6.3% | 32,155 | $437K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -16.5% | 31,430 | $427K |
| Creative Planning | 0.00% | Reduce -36.3% | 30,564 | $416K |
| Erste Asset Management GmbH | 0.01% | No change | 26,900 | $398K |
| China Universal Asset Management Co., Ltd. | 0.04% | Reduce -4.5% | 29,128 | $396K |
| Profund Advisors LLC | 0.02% | Reduce -3.0% | 27,869 | $379K |
| VELA Investment Management, LLC | 0.13% | Add +77.6% | 27,771 | $378K |
| Cibc World Markets Corp. | 0.00% | Add +137.1% | 27,582 | $375K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 26,479 | $360K |
| KLP Kapitalforvaltning As | 0.00% | No change | 26,100 | $355K |
| Raymond James Financial Inc. | 0.00% | Reduce -0.8% | 25,934 | $353K |
| AlphaQuest LLC | 0.04% | Add +260.0% | 25,060 | $341K |
| STRS Ohio | 0.00% | No change | 23,800 | $324K |
| HighTower Advisors, LLC | 0.00% | Reduce -9.7% | 23,603 | $321K |
| Polar Asset Management Partners Inc. | 0.01% | Reduce -96.2% | 20,952 | $285K |
| Empowered Funds, LLC | 0.00% | Add +11.0% | 20,639 | $281K |
| Cetera Investment Advisers | 0.00% | Reduce -11.9% | 19,993 | $272K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | New | 18,699 | $254K |
| Sei Investments Co. | 0.00% | Reduce -28.2% | 17,276 | $235K |
| Engineers Gate Manager LP | 0.00% | Reduce -67.8% | 17,198 | $234K |
| Balyasny Asset Management L.P. | 0.00% | Reduce -96.0% | 16,595 | $226K |
| Tema ETFs LLC | 0.06% | New | 15,174 | $206K |
| NEOS Investment Management LLC | 0.00% | New | 15,174 | $206K |
| Breakwater Capital Group | 0.04% | New | 15,015 | $204K |
| Royal Bank of Canada | 0.00% | Reduce -17.6% | 14,436 | $196K |
| Oxford Asset Management LLP | 0.09% | New | 14,249 | $194K |
| ADAR1 Capital Management, LLC | 0.04% | Reduce -69.0% | 13,873 | $189K |
| Verition Fund Management LLC | 0.00% | Reduce -39.3% | 13,729 | $187K |
| XTX Topco Ltd | 0.01% | Reduce -16.2% | 13,485 | $183K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 13,434 | $183K |
| Bridgefront Capital, LLC | 0.05% | New | 13,084 | $178K |
| Ameritas Investment Partners, Inc. | 0.01% | No change | 12,592 | $171K |
| Pitcairn Co. | 0.01% | Add +10.0% | 12,423 | $169K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 12,238 | $166K |
| E Fund Management Co., Ltd. | 0.01% | Add +20.7% | 12,069 | $164K |
| Entropy Technologies, LP | 0.01% | New | 11,215 | $152K |
| Moneco Advisors, LLC | 0.01% | No change | 10,600 | $144K |
| Bayesian Capital Management, LP | 0.02% | Reduce -46.2% | 10,130 | $138K |
| BNP Paribas Financial Markets | 0.00% | Reduce -45.3% | 8,715 | $118K |
| Virtus Investment Advisers, LLC | 0.03% | New | 6,991 | $95K |
| KBC Group NV | 0.00% | Add +1.8% | 6,450 | $88K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +1.3% | 4,859 | $72K |
| Shell Asset Management Co. | 0.00% | New | 4,456 | $61K |
| Amalgamated Bank | 0.00% | Add +2.7% | 4,305 | $59K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -1.3% | 3,742 | $51K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 3,685 | $50K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -71.5% | 3,212 | $44K |
| Assetmark, Inc. | 0.00% | Reduce -13.4% | 3,185 | $43K |
| BI Asset Management Fondsmaeglerselskab A/S | 0.00% | New | 2,988 | $41K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -88.1% | 2,641 | $36K |
| Caitong International Asset Management Co., Ltd | 0.02% | Add +277.0% | 2,111 | $29K |
| Cwm, LLC | 0.00% | Reduce -15.7% | 2,024 | $28K |
| Bartlett & Co. Wealth Management LLC | 0.00% | No change | 1,500 | $20K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -97.9% | 1,416 | $19K |
| Comerica Bank | 0.00% | Add +8.1% | 1,184 | $16K |
| Riverview Trust Co | 0.02% | New | 1,171 | $16K |
| Osaic Holdings, Inc. | 0.00% | Reduce -34.2% | 1,048 | $14K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 1,001 | $14K |
| Sterling Capital Management LLC | 0.00% | Reduce -44.2% | 989 | $13K |
| Versant Capital Management, Inc | 0.00% | Add +252.7% | 716 | $10K |
| Nemes Rush Group LLC | 0.00% | No change | 700 | $10K |
| Huntington National Bank | 0.00% | Add +16.9% | 693 | $9K |
| Covestor Ltd | 0.01% | Add +0.3% | 581 | $8K |
| GAMMA Investing LLC | 0.00% | Reduce -74.0% | 585 | $8K |
| US Bancorp \de | 0.00% | Reduce -47.3% | 534 | $7K |
| Signaturefd, LLC | 0.00% | Reduce -12.9% | 525 | $7K |
| Quadrant Capital Group LLC | 0.00% | New | 515 | $7K |
| Lanark Financial, Inc. | 0.00% | — | 532 | $7K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -55.6% | 473 | $7K |
| Daiwa Securities Group Inc. | 0.00% | No change | 475 | $6K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +45.6% | 431 | $6K |
| UMB Bank, n.a. | 0.00% | Add +8.9% | 416 | $6K |
| NewEdge Advisors, LLC | 0.00% | New | 400 | $5K |
| Allworth Financial LP | 0.00% | Add +2930.0% | 303 | $5K |
| City State Bank | 0.00% | No change | 250 | $3K |
| Parallel Advisors, LLC | 0.00% | Add +63.6% | 162 | $2K |
| Lindbrook Capital, LLC | 0.00% | Reduce -40.0% | 153 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Reduce -3.9% | 148 | $2K |
| Coldstream Capital Management Inc. | 0.00% | New | 145 | $2K |
| Your Advocates Ltd., LLP | 0.00% | No change | 100 | $1K |
| Harbour Investments, Inc. | 0.00% | New | 100 | $1K |
| Sherman Asset Management, Inc. | 0.00% | No change | 94 | $1K |
| Amundi | 0.00% | Add +3.5% | 88 | $1K |
| National Bank of Canada | 0.00% | Add +900.0% | 70 | $952 |
| Sierra Ocean, LLC | 0.00% | New | 66 | $897 |
| Rothschild Investment LLC | 0.00% | Reduce -35.0% | 65 | $884 |
| Bell Investment Advisors, Inc | 0.00% | No change | 52 | $707 |
| Private Wealth Asset Management, LLC | 0.00% | — | 38 | $517 |
| Optiver Holding B.V. | 0.00% | New | 31 | $421 |
| Stephens Consulting, LLC | 0.00% | New | 30 | $408 |
| SouthState Bank Corp | 0.00% | New | 30 | $408 |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 25 | $340 |
| First Horizon Advisors, Inc. | 0.00% | No change | 25 | $339 |
| Principal Securities, Inc. | 0.00% | No change | 14 | $285 |
| Hexagon Capital Partners LLC | 0.00% | Add +25.0% | 15 | $204 |
| SVB Wealth LLC | 0.00% | New | 11 | $150 |
| Farther Finance Advisors, LLC | 0.00% | Reduce -80.0% | 7 | $86 |
| SBI Securities Co., Ltd. | 0.00% | No change | 5 | $68 |
| Global Financial Private Client, LLC | 0.00% | Add +150.0% | 5 | $68 |
| SJS Investment Consulting Inc. | 0.00% | New | 3 | $41 |
| DiNuzzo Private Wealth, Inc. | 0.00% | New | 2 | $28 |
| Bay Harbor Wealth Management, LLC | 0.00% | New | 1 | $13 |
| Avion Wealth | 0.00% | New | 25 | $0 |
| Hemington Wealth Management | 0.00% | Add +45.5% | 16 | $0 |
"% of holder's portfolio" is DNLI's weight in each manager's 13F, not the share of Denali Therapeutics Inc. the manager owns.