Structure TherapeuticsGPCR
13F holders, Q2 2026 (June 30)191holders −5
27new positions
31sold out
3famous investors
$53.62avg. 13F price*
At the end of Q2 2026, 191 institutions reported holding Structure Therapeutics Inc. (GPCR) in their 13F filings, down 5 from Q1 2026. 27 opened new positions and 31 sold out. The largest holders were FMR LLC ($419.2M), Wellington Management Group LLP ($396.1M) and Avoro Capital Advisors LLC ($351.8M). 3 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Structure Therapeutics Inc.
- CUSIP
- 86366E106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 27 | $104.0M |
| Exits | 31 | $101.4M |
All 13F filers, Q1 2026 → Q2 2026: 7,139,855 shares bought and 6,147,131 shares sold, net +992,724 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 191 holders
| FMR LLC | 0.02% | Reduce -7.1% | 7,810,306 | $419.2M |
| Wellington Management Group LLP | 0.07% | Add +1.6% | 7,379,433 | $396.1M |
| Avoro Capital Advisors LLC | 3.16% | No change | 6,555,555 | $351.8M |
| Jupiter Topco LLC | 0.11% | — | 5,204,212 | $279.3M |
| Deep Track Capital, LP | 3.75% | Add +10.8% | 4,740,072 | $254.4M |
| BVF Inc. | 4.62% | Reduce -2.7% | 3,366,823 | $180.7M |
| Morgan Stanley | 0.01% | Add +21.7% | 2,806,640 | $150.6M |
| Orbimed Advisors LLC | 2.25% | Add +49.8% | 2,209,400 | $118.6M |
| Principal Financial Group Inc. | 0.05% | Reduce -0.1% | 1,752,753 | $94.1M |
| American Century Companies Inc. | 0.04% | Add +17.0% | 1,682,179 | $90.3M |
| RTW Investments, LP | 0.74% | New | 1,607,507 | $86.3M |
| Driehaus Capital Management LLC | 0.48% | Reduce -1.5% | 1,553,219 | $83.4M |
| Baker Bros. Advisors LP | 0.39% | No change | 1,432,529 | $76.9M |
| Casdin Capital, LLC | 3.16% | No change | 1,175,000 | $63.1M |
| Deerfield Management Company, L.P. | 0.73% | Add +41.4% | 1,086,000 | $58.3M |
| Capitolis Liquid Global Markets LLC | 0.24% | Reduce -9.6% | 1,041,100 | $55.9M |
| Siren, L.L.C. | 0.95% | Reduce -34.3% | 872,967 | $46.9M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -57.7% | 845,532 | $45.4M |
| Pacific Heights Asset Management LLC | 1.36% | Add +6.7% | 800,000 | $42.9M |
| Rock Springs Capital Management LP | 1.68% | Add +0.0% | 640,317 | $34.4M |
| Aberdeen Group plc | 0.05% | Add +63.3% | 639,915 | $34.3M |
| Franklin Resources Inc. | 0.01% | Add +8.9% | 578,839 | $31.1M |
| Bank of America Corp. | 0.00% | Add +148.1% | 563,422 | $30.2M |
| Alliancebernstein L.P. | 0.01% | Reduce -4.2% | 611,708 | $29.5M |
| BlackRock, Inc. | 0.00% | Add +15.7% | 511,149 | $27.4M |
| Logos Global Management LP | 1.16% | No change | 500,000 | $26.8M |
| Parkman Healthcare Partners LLC | 2.68% | Add +109.3% | 485,661 | $26.1M |
| Davern Capital Partners, LP | 4.08% | Add +252.7% | 446,059 | $23.9M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.03% | Reduce -10.5% | 418,800 | $22.5M |
| UBS Group AG | 0.00% | Add +78.0% | 378,986 | $20.3M |
| Deutsche Bank AG | 0.01% | No change | 331,867 | $17.8M |
| NEXTBio Capital Management LP | 7.71% | Add +134.5% | 312,496 | $16.8M |
| Catalio Capital Management, LP | 2.79% | Add +8.3% | 276,550 | $14.8M |
| Marshall Wace, LLP | 0.01% | Add +287.2% | 267,592 | $14.4M |
| HSG Holding Ltd | 1.19% | No change | 266,062 | $14.3M |
| SEB Asset Management AB | 0.05% | No change | 245,043 | $13.2M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -6.8% | 242,790 | $13.0M |
| Ameriprise Financial Inc. | 0.00% | Add +5.0% | 230,514 | $12.4M |
| National Bank of Canada | 0.01% | Reduce -29.3% | 215,800 | $11.6M |
| Two Sigma Investments, LP | 0.01% | Add +12.5% | 204,156 | $11.0M |
| Eversept Partners, LP | 0.57% | Add +42.2% | 196,302 | $10.5M |
| Schonfeld Strategic Advisors LLC | 0.05% | Add +15.3% | 190,685 | $10.2M |
| Woodline Partners LP | 0.03% | Reduce -19.4% | 153,808 | $8.3M |
| Nomura Asset Management International Inc. | 0.01% | Add +14.3% | 153,119 | $8.2M |
| ArrowMark Colorado Holdings LLC | 0.34% | Reduce -20.0% | 150,579 | $8.1M |
| Susquehanna Portfolio Strategies, LLC | 0.13% | Add +146.1% | 148,948 | $8.0M |
| CenterBook Partners LP | 0.39% | Add +597.0% | 148,030 | $7.9M |
| Rhenman & Partners Asset Management AB | 0.74% | Add +13.3% | 145,100 | $7.8M |
| B Group, Inc. | 4.26% | Add +9.8% | 140,000 | $7.5M |
| HighVista Strategies LLC | 1.60% | Add +5.5% | 130,784 | $7.0M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +14.6% | 125,689 | $6.7M |
| Squarepoint Ops LLC | 0.01% | Add +454.5% | 125,575 | $6.7M |
| Susquehanna International Group, LLP | 0.01% | Add +119.1% | 122,344 | $6.6M |
| D. E. Shaw & Co. | 0.00% | Reduce -43.7% | 115,300 | $6.2M |
| Voloridge Investment Management, LLC | 0.03% | Reduce -56.0% | 112,300 | $6.0M |
| Soleus Capital Management, L.P. | 0.20% | Add +33.8% | 107,000 | $5.7M |
| Avidity Partners Management LP | 0.84% | Add +226.7% | 98,000 | $5.3M |
| Geode Capital Management, LLC | 0.00% | Add +43.2% | 97,183 | $5.2M |
| Qube Research & Technologies Ltd | 0.01% | Add +26.9% | 93,403 | $5.0M |
| Peregrine Capital Management LLC | 0.16% | Reduce -5.0% | 92,229 | $4.9M |
| PFM Health Sciences, LP | 0.43% | Reduce -27.6% | 91,550 | $4.9M |
| Platinum Investment Management Ltd. | 1.19% | Add +35.1% | 90,363 | $4.8M |
| Millennium Management | 0.00% | Reduce -47.0% | 89,568 | $4.8M |
| ExodusPoint Capital Management, LP | 0.04% | New | 78,266 | $4.2M |
| Boxer Capital Management, LLC | 0.30% | No change | 75,000 | $4.0M |
| Cormorant Asset Management, LP | 0.21% | Reduce -57.1% | 75,000 | $4.0M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | New | 75,000 | $4.0M |
| Alps Advisors Inc. | 0.02% | Add +24.6% | 71,833 | $3.9M |
| TD Asset Management Inc | 0.00% | Reduce -66.3% | 68,962 | $3.7M |
| Brevan Howard Capital Management LP | 0.05% | Add +27.6% | 60,336 | $3.3M |
| Burkehill Global Management, LP | 0.12% | No change | 60,000 | $3.2M |
| Raymond James Financial Inc. | 0.00% | Add +31.5% | 59,357 | $3.2M |
| Tudor Investment Corporation | 0.01% | Reduce -28.7% | 53,656 | $2.9M |
| ANTIPODES PARTNERS Ltd | 0.05% | Add +13.0% | 51,262 | $2.8M |
| Buckland Partners Management Co LLC | 1.31% | No change | 50,000 | $2.7M |
| Seven Grand Managers, LLC | 0.11% | No change | 50,000 | $2.7M |
| DAFNA Capital Management LLC | 0.48% | No change | 46,500 | $2.5M |
| Mariner, LLC | 0.00% | Add +34.2% | 46,285 | $2.5M |
| Osaic Holdings, Inc. | 0.00% | Add +0.8% | 44,786 | $2.4M |
| State Street Corp. | 0.00% | Reduce -6.2% | 44,629 | $2.4M |
| Voya Investment Management LLC | 0.00% | No change | 44,410 | $2.4M |
| Banque Pictet & Cie SA | 0.02% | Reduce -12.2% | 43,332 | $2.3M |
| Jump Financial, LLC | 0.02% | Reduce -60.5% | 42,658 | $2.3M |
| Bank of Montreal | 0.00% | Add +6.5% | 42,570 | $2.3M |
| Cinctive Capital Management LP | 0.09% | Add +369.1% | 40,877 | $2.2M |
| Jefferies Financial Group Inc. | 0.02% | Reduce -35.1% | 40,625 | $2.2M |
| Jones Hill Capital LP | 0.46% | Reduce -59.7% | 40,567 | $2.2M |
| Stempoint Capital LP | 0.35% | Reduce -80.9% | 38,178 | $2.0M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -66.8% | 38,108 | $2.0M |
| Capital Fund Management S.A. | 0.01% | Add +14.9% | 37,281 | $2.0M |
| PSquared Asset Management AG | 0.65% | Add +6.3% | 37,200 | $2.0M |
| Flax Pond Capital, LLC | 1.35% | No change | 36,000 | $1.9M |
| TrueMark Investments, LLC | 0.23% | Reduce -2.3% | 33,600 | $1.8M |
| Nomura Asset Management Co. Ltd. | 0.00% | No change | 32,790 | $1.8M |
| DCF Advisers, LLC | 0.45% | Add +16.7% | 32,100 | $1.7M |
| Exchange Traded Concepts, LLC | 0.01% | Add +21.3% | 30,773 | $1.7M |
| Private Capital Advisors, Inc. | 0.14% | Reduce -13.5% | 29,760 | $1.6M |
| Gsa Capital Partners LLP | 0.10% | Add +107.5% | 28,665 | $1.5M |
| Sphera Funds Management LTD. | 0.22% | Reduce -43.7% | 28,600 | $1.5M |
| Verition Fund Management LLC | 0.01% | Add +1.6% | 28,519 | $1.5M |
| Y-Intercept (Hong Kong) Ltd | 0.03% | New | 27,573 | $1.5M |
| Seven Fleet Capital Management LP | 0.24% | Add +197.8% | 26,800 | $1.4M |
| MML Investors Services, LLC | 0.00% | Add +84.3% | 25,601 | $1.4M |
| Birchview Capital, LP | 0.60% | Reduce -76.0% | 24,000 | $1.3M |
| Nomura Holdings Inc. | 0.01% | New | 22,873 | $1.2M |
| Barclays PLC | 0.00% | Add +5.4% | 20,231 | $1.1M |
| Handelsbanken Fonder AB | 0.00% | New | 19,400 | $1.0M |
| BNP Paribas Financial Markets | 0.00% | Add +63.4% | 17,781 | $954K |
| ADAR1 Capital Management, LLC | 0.04% | New | 17,500 | $939K |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 17,297 | $928K |
| Stifel Financial Corp. | 0.00% | Add +32.5% | 15,032 | $807K |
| LPL Financial LLC | 0.00% | Add +54.8% | 14,333 | $769K |
| Wexford Capital LP | 0.10% | No change | 13,709 | $736K |
| Sei Investments Co. | 0.00% | Reduce -2.2% | 13,684 | $734K |
| Brandywine Managers, LLC | 0.35% | No change | 13,357 | $717K |
| Gladstone Institutional Advisory LLC | 0.02% | New | 13,275 | $712K |
| Fulcrum Asset Management LLP | 0.07% | New | 13,252 | $685K |
| China Universal Asset Management Co., Ltd. | 0.04% | Reduce -10.2% | 12,409 | $666K |
| Envestnet Asset Management Inc. | 0.00% | Add +1.7% | 11,575 | $621K |
| Verdad Advisers, LP | 0.58% | No change | 11,335 | $608K |
| DNB Asset Management AS | 0.00% | Add +31.6% | 10,779 | $579K |
| Fox Run Management, L.L.C. | 0.10% | New | 10,776 | $578K |
| Wells Fargo & Company | 0.00% | Add +33.0% | 10,398 | $558K |
| HighTower Advisors, LLC | 0.00% | Add +4.3% | 10,029 | $538K |
| Quinn Opportunity Partners LLC | 0.03% | No change | 10,000 | $537K |
| SmartHarvest Portfolios, LLC | 0.17% | Add +9.6% | 9,928 | $533K |
| Citigroup Inc. | 0.00% | Reduce -52.8% | 9,680 | $520K |
| Gilbert & Cook, Inc. | 0.06% | Reduce -0.3% | 9,167 | $492K |
| IMC-Chicago, LLC | 0.00% | New | 8,618 | $463K |
| Simplex Trading, LLC | 0.01% | New | 7,871 | $422K |
| Clearstead Advisors, LLC | 0.00% | New | 7,826 | $420K |
| Quadcap Wealth Management, LLC | 0.04% | Add +61.5% | 7,635 | $410K |
| Virtus Investment Advisers, LLC | 0.10% | Add +87.5% | 7,622 | $409K |
| Allianz Asset Management GmbH | 0.00% | Reduce -11.6% | 7,600 | $408K |
| Mission Wealth Management, LP | 0.01% | No change | 7,583 | $407K |
| Vestmark Advisory Solutions, Inc. | 0.00% | No change | 7,534 | $404K |
| Parallel Advisors, LLC | 0.01% | No change | 7,352 | $395K |
| Cetera Investment Advisers | 0.00% | Reduce -14.0% | 6,638 | $356K |
| EntryPoint Capital, LLC | 0.08% | New | 6,136 | $329K |
| Janney Montgomery Scott LLC | 0.00% | Reduce -21.3% | 5,364 | $288K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -20.3% | 5,107 | $274K |
| Northern Trust Corp. | 0.00% | New | 5,080 | $273K |
| Concurrent Investment Advisors, LLC | 0.00% | No change | 5,000 | $268K |
| Bellevue Group AG | 0.01% | Reduce -30.0% | 4,762 | $256K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.07% | Add +10.9% | 4,645 | $249K |
| Independent Advisor Alliance | 0.01% | Reduce -39.0% | 4,543 | $244K |
| Sectoral Asset Management Inc. | 0.16% | Reduce -69.3% | 4,325 | $232K |
| PEAK6 LLC | 0.01% | Reduce -31.4% | 4,155 | $223K |
| Walleye Trading LLC | 0.00% | New | 4,113 | $221K |
| Prospera Financial Services Inc | 0.00% | New | 4,100 | $220K |
| Gabelli Funds LLC | 0.00% | New | 4,050 | $217K |
| Invesco Ltd. | 0.00% | Reduce -13.8% | 3,951 | $212K |
| JPMorgan Chase & Co. | 0.00% | Reduce -98.1% | 3,984 | $206K |
| Nano Cap New Millennium Growth Fund L P | 0.14% | Add +133.3% | 3,500 | $188K |
| E. Ohman J:or Asset Management AB | 0.00% | Reduce -28.9% | 3,212 | $172K |
| State of Wyoming | 0.02% | Add +616.2% | 3,101 | $166K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -2.5% | 2,782 | $149K |
| Assetmark, Inc. | 0.00% | Add +7.2% | 2,726 | $146K |
| Natixis | 0.00% | New | 2,482 | $135K |
| Rockefeller Capital Management L.P. | 0.00% | Add +13.2% | 2,514 | $135K |
| SG Americas Securities, LLC | 0.00% | Reduce -8.4% | 2,427 | $130K |
| Sterling Capital Management LLC | 0.00% | Add +246.6% | 2,045 | $110K |
| Farther Finance Advisors, LLC | 0.00% | Add +77.9% | 1,656 | $89K |
| GF Fund Management Co. LTD. | 0.00% | Add +10.1% | 1,651 | $89K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 1,500 | $80K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 1,400 | $75K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +38.9% | 897 | $48K |
| IFP Advisors, Inc | 0.00% | New | 858 | $46K |
| GAMMA Investing LLC | 0.00% | Reduce -16.3% | 836 | $45K |
| Royal Bank of Canada | 0.00% | Reduce -23.8% | 550 | $30K |
| Wolff Wiese Magana LLC | 0.01% | No change | 400 | $21K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +81.6% | 385 | $21K |
| North Star Investment Management Corp. | 0.00% | No change | 330 | $18K |
| Godfrey Financial Associates, Inc. | 0.01% | New | 245 | $13K |
| Quarry LP | 0.00% | New | 245 | $13K |
| Jones Financial Companies LLLP | 0.00% | Reduce -48.7% | 175 | $9K |
| Dynamic Wealth Strategies, LLC | 0.00% | No change | 150 | $8K |
| Key Financial Inc | 0.00% | No change | 100 | $5K |
| SHP Wealth Management | 0.00% | No change | 100 | $5K |
| Signaturefd, LLC | 0.00% | No change | 100 | $5K |
| Huntington National Bank | 0.00% | Add +3850.0% | 79 | $4K |
| Rakuten Securities, Inc. | 0.00% | No change | 60 | $3K |
| Arax Advisory Partners | 0.00% | New | 34 | $2K |
| Transamerica Financial Advisors, LLC | 0.00% | No change | 22 | $1K |
| Ares Financial Consulting, LLC | 0.00% | New | 20 | $1K |
| Bessemer Group Inc. | 0.00% | New | 22 | $1K |
| Capital Analysts, LLC | 0.00% | No change | 18 | $1K |
| Smartleaf Asset Management LLC | 0.00% | No change | 17 | $879 |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 10 | $537 |
| Cullen/Frost Bankers, Inc. | 0.00% | No change | 8 | $429 |
| Larson Financial Group LLC | 0.00% | Add +20.0% | 6 | $322 |
"% of holder's portfolio" is GPCR's weight in each manager's 13F, not the share of Structure Therapeutics Inc. the manager owns.