Opko HealthOPK
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 235 institutions reported holding Opko Health Inc. (OPK) in their 13F filings, up 1 from Q3 2024. 26 opened new positions and 29 sold out. The largest holders were Rubric Capital Management LP ($71.6M), Vanguard Group Inc. ($42.9M) and BlackRock, Inc. ($41.4M). 6 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Opko Health Inc.
- CUSIP
- 68375N103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 26 | $5.2M |
| Exits | 29 | $3.5M |
All 13F filers, Q3 2024 → Q4 2024: 22,776,719 shares bought and 12,143,372 shares sold, net +10,633,347 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 235 holders
| Rubric Capital Management LP | 1.30% | No change | 48,706,640 | $71.6M |
| Vanguard Group Inc. | 0.00% | Reduce -0.0% | 29,206,331 | $42.9M |
| BlackRock, Inc. | 0.00% | Reduce -1.5% | 28,168,612 | $41.4M |
| State Street Corp. | 0.00% | Add +4.1% | 9,074,898 | $13.3M |
| Geode Capital Management, LLC | 0.00% | Add +0.1% | 8,385,218 | $12.3M |
| UBS Group AG | 0.00% | Add +469.8% | 4,822,847 | $7.1M |
| Millennium Management | 0.01% | Add +85.3% | 4,588,526 | $6.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +40.0% | 3,839,820 | $5.6M |
| Northern Trust Corp. | 0.00% | Add +4.7% | 3,697,774 | $5.4M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -17.0% | 3,497,406 | $5.1M |
| Citadel Advisors | 0.00% | Add +28.3% | 3,210,290 | $4.7M |
| Morgan Stanley | 0.00% | Add +138.3% | 3,167,942 | $4.7M |
| Jane Street Group, LLC | 0.01% | Add +429.1% | 2,806,921 | $4.1M |
| Lazard Asset Management LLC | 0.01% | Add +143.6% | 2,548,667 | $3.7M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -2.6% | 2,268,666 | $3.3M |
| Two Sigma Investments, LP | 0.01% | Add +136.1% | 1,647,567 | $2.4M |
| JPMorgan Chase & Co. | 0.00% | Reduce -14.3% | 1,574,971 | $2.3M |
| Invesco Ltd. | 0.00% | Reduce -74.2% | 1,554,489 | $2.3M |
| Nuveen Asset Management, LLC | 0.00% | Add +42.3% | 1,432,404 | $2.1M |
| Altshuler Shaham Ltd | 0.07% | New | 1,411,019 | $2.1M |
| Y.D. More Investments Ltd | 0.19% | Reduce -18.6% | 1,395,768 | $2.1M |
| AWM Investment Company, Inc. | 0.23% | No change | 1,300,000 | $1.9M |
| Voya Investment Management LLC | 0.00% | Reduce -39.4% | 1,255,034 | $1.8M |
| Tejara Capital Ltd | 1.18% | Add +11.3% | 1,225,650 | $1.8M |
| PFG Investments, LLC | 0.11% | Add +9.4% | 1,160,885 | $1.7M |
| Norges Bank | 0.00% | No change | 1,127,468 | $1.7M |
| Intrinsic Edge Capital Management LLC | 0.22% | No change | 1,100,000 | $1.6M |
| Gsa Capital Partners LLP | 0.12% | New | 1,082,206 | $1.6M |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.7% | 1,024,907 | $1.5M |
| Marshall Wace, LLP | 0.00% | Add +856.5% | 921,487 | $1.4M |
| Barclays PLC | 0.00% | Add +68.7% | 916,368 | $1.3M |
| Clearstead Advisors, LLC | 0.02% | Add +0.1% | 883,042 | $1.3M |
| Assenagon Asset Management S.A. | 0.00% | Reduce -42.5% | 856,738 | $1.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +24.5% | 753,380 | $1.1M |
| Swiss National Bank | 0.00% | No change | 685,455 | $1.0M |
| HRT Financial LP | 0.01% | Add +24.4% | 669,636 | $984K |
| Group One Trading LLC | 0.03% | Add +192.8% | 647,085 | $951K |
| Bank of America Corp. | 0.00% | Add +94.7% | 581,582 | $855K |
| Osaic Holdings, Inc. | 0.00% | Add +1131.8% | 531,826 | $782K |
| Rhumbline Advisers | 0.00% | Reduce -5.1% | 518,823 | $763K |
| Skaana Management L.P. | 0.90% | Reduce -43.3% | 478,614 | $704K |
| T. Rowe Price Associates Inc. | 0.00% | Add +4.3% | 455,521 | $670K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -0.1% | 434,035 | $638K |
| Engineers Gate Manager LP | 0.01% | Reduce -2.7% | 414,453 | $609K |
| Two Sigma Advisers, LP | 0.00% | Add +2.3% | 381,197 | $560K |
| Alliancebernstein L.P. | 0.00% | Reduce -22.9% | 375,320 | $552K |
| Legal & General Group Plc | 0.00% | Reduce -5.1% | 370,438 | $545K |
| Exchange Traded Concepts, LLC | 0.01% | Reduce -9.1% | 351,896 | $517K |
| Essential Planning, LLC. | 0.00% | New | 331,175 | $506K |
| California State Teachers Retirement System | 0.00% | Reduce -1.1% | 324,117 | $476K |
| Deutsche Bank AG | 0.00% | Add +48.3% | 309,867 | $456K |
| AQR Capital Management | 0.00% | Add +268.0% | 283,918 | $417K |
| Citigroup Inc. | 0.00% | Add +13.1% | 270,114 | $397K |
| Tudor Investment Corporation | 0.00% | No change | 244,821 | $360K |
| Royal Bank of Canada | 0.00% | Add +8.9% | 241,928 | $356K |
| Wells Fargo & Company | 0.00% | Add +14.9% | 229,262 | $337K |
| Janus Henderson Group PLC | 0.00% | No change | 206,314 | $304K |
| MetLife Investment Management, LLC | 0.00% | Add +40.8% | 202,165 | $297K |
| Intech Investment Management LLC | 0.00% | Add +58.0% | 201,478 | $296K |
| XTX Topco Ltd | 0.02% | Add +79.3% | 194,804 | $286K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.5% | 186,783 | $275K |
| State Board of Administration of Florida Retirement System | 0.00% | Reduce -36.8% | 176,260 | $259K |
| GAMCO Investors | 0.00% | No change | 175,000 | $257K |
| ExodusPoint Capital Management, LP | 0.00% | New | 173,700 | $255K |
| Gabelli Funds LLC | 0.00% | No change | 170,000 | $250K |
| Corebridge Financial, Inc. | 0.00% | Reduce -7.0% | 161,934 | $238K |
| X-Square Capital, LLC | 0.10% | Reduce -4.6% | 161,726 | $238K |
| Raymond James Financial Inc. | 0.00% | — | 150,670 | $221K |
| Teton Advisors, Inc. | 0.12% | No change | 150,000 | $221K |
| Renaissance Technologies | 0.00% | Reduce -68.2% | 145,977 | $215K |
| Susquehanna International Group, LLP | 0.00% | Add +13.4% | 145,136 | $213K |
| Numerai GP LLC | 0.06% | New | 139,755 | $205K |
| Squarepoint Ops LLC | 0.00% | Reduce -57.2% | 135,338 | $199K |
| Whitefort Capital Management, LP | 0.10% | No change | 134,490 | $198K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -3.1% | 130,781 | $192K |
| Csenge Advisory Group | 0.01% | No change | 117,000 | $172K |
| Highline Wealth Partners LLC | 0.06% | No change | 116,680 | $172K |
| Van Eck Associates Corp. | 0.00% | Reduce -0.6% | 106,784 | $157K |
| Comerica Bank | 0.00% | Add +18.2% | 106,369 | $156K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -0.4% | 103,110 | $152K |
| Arizona State Retirement System | 0.00% | Add +0.5% | 100,888 | $148K |
| Phoenix Financial Ltd. | 0.00% | No change | 100,000 | $148K |
| Intrepid Capital Management Inc. | 0.09% | No change | 100,000 | $147K |
| Wolverine Trading, LLC | 0.00% | Add +39.3% | 97,722 | $144K |
| Ameriprise Financial Inc. | 0.00% | Reduce -5.5% | 94,391 | $139K |
| ProShare Advisors LLC | 0.00% | Add +49.0% | 91,730 | $135K |
| Hollencrest Capital Management | 0.01% | No change | 90,000 | $132K |
| 360 Financial, Inc. | 0.04% | Reduce -0.1% | 80,800 | $119K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | — | 77,449 | $114K |
| Two Sigma Securities, LLC | 0.02% | Reduce -33.6% | 75,782 | $111K |
| KLP Kapitalforvaltning As | 0.00% | — | 74,000 | $109K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | New | 69,591 | $102K |
| Cascade Financial Partners, LLC | 0.01% | No change | 66,490 | $98K |
| Brevan Howard Capital Management LP | 0.00% | Reduce -35.2% | 66,282 | $97K |
| Pictet Asset Management Holding SA | 0.00% | No change | 65,495 | $96K |
| Catalyst Funds Management Pty Ltd | 0.02% | New | 61,600 | $91K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 61,502 | $90K |
| New York State Common Retirement Fund | 0.00% | No change | 60,801 | $89K |
| Cetera Investment Advisers | 0.00% | Reduce -1.8% | 60,556 | $89K |
| Kestra Private Wealth Services, LLC | 0.00% | Add +5.7% | 59,700 | $88K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 56,800 | $83K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 55,140 | $81K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 54,068 | $79K |
| BNP Paribas Financial Markets | 0.00% | Reduce -79.0% | 51,849 | $76K |
| First Manhattan Co. Llc. | 0.00% | No change | 51,750 | $76K |
| Transcend Capital Advisors, LLC | 0.01% | No change | 50,850 | $75K |
| Kestra Advisory Services, LLC | 0.00% | No change | 50,307 | $74K |
| Farmers National Bank | 0.02% | — | 50,300 | $74K |
| Humankind Investments LLC | 0.02% | Add +0.6% | 47,621 | $70K |
| Mercer Global Advisors Inc. | 0.00% | Add +105.6% | 43,167 | $63K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.02% | Reduce -55.1% | 41,589 | $61K |
| World Investment Advisors | 0.00% | Reduce -0.2% | 40,618 | $60K |
| Shell Asset Management Co. | 0.00% | Reduce -1.1% | 40,397 | $59K |
| HighTower Advisors, LLC | 0.00% | Reduce -14.7% | 39,991 | $59K |
| Victory Capital Management Inc. | 0.00% | Reduce -7.2% | 38,327 | $56K |
| HSBC Holdings PLC | 0.00% | Reduce -8.3% | 37,886 | $56K |
| Captrust Financial Advisors | 0.00% | Add +3.9% | 37,530 | $55K |
| Choreo, LLC | 0.00% | Reduce -49.0% | 37,086 | $55K |
| RK Asset Management, LLC | 0.04% | Reduce -0.6% | 36,485 | $54K |
| Ieq Capital, LLC | 0.00% | New | 35,419 | $52K |
| Private Advisor Group, LLC | 0.00% | No change | 35,301 | $52K |
| State of Wisconsin Investment Board | 0.00% | Add +22.3% | 33,876 | $50K |
| Zacks Investment Management | 0.00% | New | 33,300 | $49K |
| LPL Financial LLC | 0.00% | Reduce -68.2% | 33,132 | $49K |
| Atom Investors LP | 0.01% | Reduce -3.4% | 32,767 | $48K |
| Operose Advisors LLC | 0.02% | No change | 32,000 | $47K |
| STRS Ohio | 0.00% | No change | 31,900 | $47K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 31,889 | $47K |
| Prudential Financial Inc. | 0.00% | Reduce -69.0% | 31,356 | $46K |
| Cibc World Markets Corp. | 0.00% | New | 30,482 | $45K |
| IPG Investment Advisors LLC | 0.01% | No change | 30,000 | $44K |
| Diversify Wealth Management, LLC | 0.00% | No change | 30,000 | $44K |
| Norris Perne & French LLP | 0.00% | Add +11.1% | 30,000 | $44K |
| Brighton Jones LLC | 0.00% | No change | 30,000 | $44K |
| Orion Porfolio Solutions, LLC | 0.00% | No change | 30,000 | $44K |
| Orion Portfolio Solutions, LLC | 0.00% | No change | 30,000 | $44K |
| Cibc World Market Inc. | 0.00% | New | 29,928 | $44K |
| Equitable Holdings, Inc. | 0.00% | New | 28,930 | $43K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +75.3% | 28,908 | $42K |
| EP Wealth Advisors, LLC | 0.00% | No change | 28,900 | $42K |
| Cim Investment Management Inc. | 0.01% | No change | 27,331 | $40K |
| PBMares Wealth Management LLC | 0.01% | Add +29.3% | 27,021 | $40K |
| SlateStone Wealth, LLC | 0.00% | No change | 25,770 | $38K |
| Mackenzie Financial Corp. | 0.00% | No change | 25,843 | $38K |
| FMR LLC | 0.00% | Add +11.5% | 24,296 | $36K |
| Creative Planning | 0.00% | Reduce -9.9% | 24,264 | $36K |
| Moseley Investment Management Inc. | 0.01% | No change | 24,153 | $36K |
| Xponance LLC | 0.00% | Add +12.9% | 23,279 | $34K |
| Point72 (DIFC) Ltd | 0.00% | Reduce -52.6% | 22,745 | $33K |
| Atria Wealth Solutions, Inc. | 0.00% | No change | 22,400 | $33K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 22,300 | $33K |
| CIBC Asset Management Inc | 0.00% | Add +7.8% | 21,918 | $32K |
| Sax Wealth Advisors, LLC | 0.00% | No change | 20,110 | $30K |
| N.E.W. Advisory Services LLC | 0.00% | Reduce -19.5% | 20,075 | $30K |
| Sovereign Financial Group, Inc. | 0.01% | No change | 20,074 | $30K |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 0.00% | No change | 20,000 | $29K |
| Cumberland Advisors Inc. | 0.01% | No change | 19,500 | $29K |
| Principal Financial Group Inc. | 0.00% | Reduce -20.7% | 18,032 | $27K |
| Sigma Planning Corp | 0.00% | No change | 17,972 | $26K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -88.8% | 17,823 | $26K |
| Shufro Rose & Co. LLC | 0.00% | No change | 17,000 | $25K |
| Stifel Financial Corp. | 0.00% | Add +0.6% | 16,783 | $25K |
| Westmount Partners, LLC | 0.01% | No change | 16,550 | $24K |
| Commons Capital, LLC | 0.02% | No change | 16,300 | $24K |
| Formidable Asset Management, LLC | 0.00% | Reduce -3.8% | 15,046 | $22K |
| C2C Wealth Management, LLC | 0.02% | New | 15,015 | $22K |
| Capital Square, LLC | 0.01% | Reduce -3.3% | 14,800 | $22K |
| Colony Family Offices, LLC | 0.01% | No change | 14,729 | $22K |
| Granite Investment Partners, LLC | 0.00% | Add +4.0% | 14,356 | $21K |
| Capital Advisors Inc. | 0.00% | New | 150,000 | $20K |
| GTS Securities LLC | 0.00% | Reduce -65.0% | 12,944 | $19K |
| Mill Creek Capital Advisors, LLC | 0.00% | No change | 12,383 | $18K |
| Farther Finance Advisors, LLC | 0.00% | No change | 11,849 | $17K |
| Traphagen Investment Advisors LLC | 0.00% | No change | 11,680 | $17K |
| HBK Sorce Advisory LLC | 0.00% | No change | 11,409 | $17K |
| Stillwater Capital Advisors, LLC | 0.00% | No change | 11,380 | $17K |
| Public Employees Retirement System of Ohio | 0.00% | Add +1.8% | 11,055 | $16K |
| Pathstone Holdings, LLC | 0.00% | No change | 10,541 | $16K |
| Key Financial Inc | 0.00% | No change | 11,000 | $16K |
| Amalgamated Bank | 0.00% | No change | 11,110 | $16K |
| Balyasny Asset Management L.P. | 0.00% | New | 10,764 | $16K |
| Sterling Capital Management LLC | 0.00% | Add +809.5% | 10,432 | $15K |
| Steward Partners Investment Advisory, LLC | 0.00% | Reduce -0.7% | 10,293 | $15K |
| Sei Investments Co. | 0.00% | No change | 10,163 | $15K |
| Abel Hall, LLC | 0.01% | Reduce -1.2% | 10,126 | $15K |
| McAdam, LLC | 0.00% | Reduce -10.1% | 10,054 | $15K |
| Kovack Advisors, Inc. | 0.00% | Add +0.0% | 10,001 | $15K |
| MRP Capital Investments, LLC | 0.01% | No change | 10,000 | $15K |
| Greenbush Financial Group, LLC | 0.01% | — | 10,000 | $15K |
| KLCM Advisors, Inc. | 0.00% | No change | 10,000 | $15K |
| Diversified Trust Co. | 0.00% | No change | 10,000 | $15K |
| Jones Financial Companies LLLP | 0.00% | Add +3.0% | 8,625 | $13K |
| Aventura Private Wealth, LLC | 0.01% | — | 8,400 | $12K |
| Aster Capital Management (DIFC) Ltd | 0.00% | Reduce -28.6% | 7,494 | $11K |
| Cwm, LLC | 0.00% | Add +937.9% | 7,016 | $10K |
| Raiffeisen Bank International AG | 0.00% | — | 6,521 | $10K |
| National Bank of Canada | 0.00% | No change | 6,200 | $9K |
| Penserra Capital Management LLC | 0.00% | Add +3.7% | 6,098 | $8K |
| Zazove Associates LLC | 0.01% | New | 4,900 | $7K |
| Cubist Systematic Strategies, LLC | 0.00% | Reduce -94.3% | 4,827 | $7K |
| Nisa Investment Advisors, LLC | 0.00% | Add +10.2% | 4,742 | $7K |
| FSA Wealth Management LLC | 0.00% | No change | 3,950 | $6K |
| Smartleaf Asset Management LLC | 0.00% | Add +702.3% | 3,803 | $6K |
| Gables Capital Management Inc. | 0.00% | New | 3,000 | $4K |
| Moser Wealth Advisors, LLC | 0.00% | No change | 2,392 | $4K |
| Quarry LP | 0.00% | Add +2.9% | 1,712 | $3K |
| Allworth Financial LP | 0.00% | Add +163.5% | 1,623 | $2K |
| CoreCap Advisors, LLC | 0.00% | Reduce -2.3% | 1,600 | $2K |
| Transce3nd, LLC | 0.00% | — | 1,456 | $2K |
| GeoWealth Management, LLC | 0.00% | No change | 1,215 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +14.5% | 1,146 | $2K |
| PFS Partners, LLC | 0.00% | No change | 1,100 | $2K |
| Caitong International Asset Management Co., Ltd | 0.00% | — | 1,036 | $2K |
| MAI Capital Management | 0.00% | New | 1,000 | $1K |
| Signaturefd, LLC | 0.00% | No change | 1,000 | $1K |
| Salomon & Ludwin, LLC | 0.00% | Reduce -0.5% | 995 | $1K |
| Russell Investments Group, Ltd. | 0.00% | Add +118.8% | 840 | $1K |
| CBIZ Investment Advisory Services, LLC | 0.00% | New | 698 | $1K |
| US Bancorp \de | 0.00% | No change | 600 | $882 |
| Fifth Third Bancorp | 0.00% | New | 550 | $809 |
| Northwestern Mutual Wealth Management Co. | 0.00% | Add +100.0% | 454 | $667 |
| Sugar Maple Asset Management, LLC | 0.00% | New | 350 | $515 |
| Pittenger & Anderson Inc. | 0.00% | No change | 250 | $368 |
| Rothschild Investment LLC | 0.00% | No change | 200 | $294 |
| IFP Advisors, Inc | 0.00% | New | 103 | $151 |
| Salem Investment Counselors Inc. | 0.00% | No change | 100 | $147 |
| NFSG Corp | 0.00% | New | 100 | $147 |
| SBI Securities Co., Ltd. | 0.00% | — | 91 | $134 |
| Larson Financial Group LLC | 0.00% | Reduce -86.2% | 40 | $59 |
| NewEdge Advisors, LLC | 0.00% | Add +1800.0% | 19 | $28 |
| True Wealth Design, LLC | 0.00% | New | 8 | $12 |
| Darwin Wealth Management, LLC | 0.00% | No change | 5 | $7 |
| Cornerstone Planning Group LLC | 0.00% | No change | 1 | $1 |
| Centerpoint Advisors, LLC | 0.00% | No change | 100 | $0 |
| Covestor Ltd | 0.00% | Add +7.1% | 105 | $0 |
"% of holder's portfolio" is OPK's weight in each manager's 13F, not the share of Opko Health Inc. the manager owns.