Uniqure NVQURE
13F holders, Q4 2025 (December 31)226holders +7
62new positions
63sold out
6famous investors
$23.93avg. 13F price*
At the end of Q4 2025, 226 institutions reported holding Uniqure NV (QURE) in their 13F filings, up 7 from Q3 2025. 62 opened new positions and 63 sold out. The largest holders were FMR LLC ($149.3M), Avoro Capital Advisors LLC ($147.2M) and RTW Investments, LP ($88.8M). 6 famous investors held it, including Lee Ainslie (0.2% of Maverick Capital's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Uniqure NV
- CUSIP
- N90064101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 62 | $215.8M |
| Exits | 63 | $450.6M |
All 13F filers, Q3 2025 → Q4 2025: 23,524,418 shares bought and 17,384,104 shares sold, net +6,140,314 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 226 holders
| FMR LLC | 0.01% | Add +3.0% | 6,240,936 | $149.3M |
| Avoro Capital Advisors LLC | 1.45% | Add +38.4% | 6,150,000 | $147.2M |
| RTW Investments, LP | 0.89% | Reduce -16.1% | 3,711,462 | $88.8M |
| Aberdeen Group plc | 0.14% | Add +25.1% | 3,678,640 | $88.0M |
| State Street Corp. | 0.00% | Add +123.8% | 3,231,043 | $77.3M |
| JPMorgan Chase & Co. | 0.00% | Add +155.3% | 2,934,626 | $70.2M |
| BlackRock, Inc. | 0.00% | Add +36.6% | 1,974,988 | $47.3M |
| Two Sigma Investments, LP | 0.05% | Add +61.7% | 1,451,284 | $34.7M |
| MPM Bioimpact LLC | 3.78% | New | 1,381,628 | $33.1M |
| Jennison Associates LLC | 0.02% | Add +37.2% | 1,371,190 | $32.8M |
| Susquehanna International Group, LLP | 0.04% | Add +440.2% | 1,218,350 | $29.2M |
| Montanova Capital, LLC | 0.73% | New | 1,216,734 | $29.1M |
| Goldman Sachs Group Inc. | 0.00% | Add +76.3% | 1,167,608 | $27.9M |
| Two Sigma Advisers, LP | 0.05% | Add +171.2% | 1,110,400 | $26.6M |
| Vanguard Group Inc. | 0.00% | Reduce -6.5% | 1,051,379 | $25.2M |
| Artia Global Partners LP | 3.94% | Add +55.4% | 1,023,539 | $24.5M |
| Integral Health Asset Management, LLC | 1.09% | Add +50.0% | 900,000 | $21.5M |
| Millennium Management | 0.01% | Add +319.4% | 803,605 | $19.2M |
| Geode Capital Management, LLC | 0.00% | Add +7.5% | 776,071 | $18.6M |
| Fiera Capital Corp | 0.06% | New | 768,510 | $18.4M |
| Franklin Resources Inc. | 0.00% | Reduce -62.5% | 746,602 | $17.9M |
| Orbimed Advisors LLC | 0.36% | Add +60.8% | 737,400 | $17.6M |
| Morgan Stanley | 0.00% | Add +123.0% | 716,927 | $17.2M |
| Nantahala Capital Management, LLC | 1.00% | Reduce -30.6% | 699,298 | $16.7M |
| Logos Global Management LP | 1.08% | Add +125.0% | 675,000 | $16.2M |
| Tyro Capital Management LLC | 4.94% | New | 663,929 | $15.9M |
| Maverick Capital | 0.17% | New | 661,820 | $15.8M |
| Assenagon Asset Management S.A. | 0.02% | New | 606,923 | $14.5M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 1.11% | No change | 521,677 | $12.5M |
| Eventide Asset Management, LLC | 0.19% | New | 498,212 | $11.9M |
| UBS Group AG | 0.00% | Add +139.8% | 491,454 | $11.8M |
| Citadel Advisors | 0.01% | Add +9.2% | 469,300 | $11.2M |
| Whitefort Capital Management, LP | 3.46% | New | 459,000 | $11.0M |
| Privium Fund Management B.V. | 1.83% | Add +7.8% | 416,270 | $10.0M |
| 683 Capital Management, LLC | 0.81% | Reduce -64.0% | 384,950 | $9.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.4% | 362,878 | $8.7M |
| Readystate Asset Management LP | 0.66% | New | 361,560 | $8.7M |
| Fred Alger Management, LLC | 0.03% | Reduce -73.3% | 344,878 | $8.3M |
| Bank of America Corp. | 0.00% | Add +11.7% | 329,525 | $7.9M |
| First Turn Management, LLC | 0.88% | New | 321,655 | $7.7M |
| HRT Financial LP | 0.02% | New | 310,050 | $7.4M |
| Jump Financial, LLC | 0.10% | Add +7901.3% | 306,131 | $7.3M |
| Boxer Capital Management, LLC | 1.52% | Reduce -63.8% | 290,000 | $6.9M |
| Catalio Capital Management, LP | 1.22% | Add +1.9% | 288,345 | $6.9M |
| Nomura Asset Management International Inc. | 0.01% | — | 258,211 | $6.2M |
| Parkman Healthcare Partners LLC | 0.59% | Reduce -25.5% | 257,382 | $6.2M |
| ADAR1 Capital Management, LLC | 0.42% | Add +76.4% | 235,155 | $5.6M |
| Freshford Capital Management, LLC | 2.20% | New | 229,613 | $5.5M |
| BNP Paribas Financial Markets | 0.00% | Reduce -42.6% | 221,343 | $5.3M |
| Voss Capital, LP | 0.27% | Add +68.0% | 210,000 | $5.0M |
| Barclays PLC | 0.00% | Add +81.5% | 209,790 | $5.0M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -77.2% | 208,646 | $5.0M |
| Eagle Health Investments LP | 1.08% | New | 205,247 | $4.9M |
| Citigroup Inc. | 0.00% | Add +1496.2% | 184,765 | $4.4M |
| Caption Management, LLC | 0.19% | Reduce -61.3% | 177,277 | $4.2M |
| Sofinnova Investments, Inc. | 0.18% | Add +29.0% | 176,513 | $4.2M |
| Squarepoint Ops LLC | 0.01% | Reduce -3.2% | 176,000 | $4.2M |
| Northern Trust Corp. | 0.00% | Add +10.8% | 168,820 | $4.0M |
| Rafferty Asset Management, LLC | 0.01% | Add +99.1% | 164,937 | $3.9M |
| Alyeska Investment Group, L.P. | 0.01% | Add +277.6% | 151,058 | $3.6M |
| New York State Common Retirement Fund | 0.00% | New | 147,549 | $3.5M |
| Flax Pond Capital, LLC | 2.61% | — | 146,498 | $3.5M |
| Balyasny Asset Management L.P. | 0.01% | Reduce -59.3% | 135,644 | $3.2M |
| D. E. Shaw & Co. | 0.00% | Add +305.6% | 131,956 | $3.2M |
| Silverarc Capital Management, LLC | 0.44% | Reduce -72.3% | 126,047 | $3.0M |
| Hudson Bay Capital Management LP | 0.02% | Add +2806.4% | 125,500 | $3.0M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -34.9% | 122,529 | $2.9M |
| Nan Fung Trinity (hk) Ltd. | 0.22% | New | 115,494 | $2.8M |
| Simplex Trading, LLC | 0.07% | Add +62.8% | 110,675 | $2.6M |
| Envestnet Asset Management Inc. | 0.00% | Add +762.4% | 99,593 | $2.4M |
| Ikarian Capital, LLC | 0.28% | Add +55.4% | 91,060 | $2.2M |
| Jefferies Financial Group Inc. | 0.02% | No change | 90,542 | $2.2M |
| Deeter Investments LLP | 0.46% | — | 89,085 | $2.1M |
| Marex Group Ltd | 0.02% | Reduce -1.0% | 85,993 | $2.1M |
| Royal Bank of Canada | 0.00% | Reduce -59.5% | 85,640 | $2.0M |
| Clearline Capital LP | 0.15% | New | 83,681 | $2.0M |
| Capital Fund Management S.A. | 0.02% | New | 82,978 | $2.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 80,249 | $1.9M |
| Rhenman & Partners Asset Management AB | 0.18% | New | 79,375 | $1.9M |
| Swiss National Bank | 0.00% | Add +3.5% | 79,000 | $1.9M |
| Walleye Capital LLC | 0.01% | Reduce -23.2% | 78,996 | $1.9M |
| Atom Investors LP | 0.15% | Add +65.4% | 78,209 | $1.9M |
| Moore Capital Management, LP | 0.04% | New | 75,000 | $1.8M |
| Tudor Investment Corporation | 0.01% | Add +157.8% | 74,036 | $1.8M |
| ExodusPoint Capital Management, LP | 0.02% | New | 73,775 | $1.8M |
| Algert Global LLC | 0.03% | Add +216.3% | 72,150 | $1.7M |
| Ameriprise Financial Inc. | 0.00% | Reduce -55.5% | 70,796 | $1.7M |
| Wells Fargo & Company | 0.00% | Add +547.8% | 70,236 | $1.7M |
| Hennion & Walsh Asset Management, Inc. | 0.06% | Add +31.2% | 67,739 | $1.6M |
| SG Americas Securities, LLC | 0.00% | Add +508.1% | 64,326 | $1.5M |
| Eversept Partners, LP | 0.08% | Reduce -92.8% | 62,820 | $1.5M |
| Profund Advisors LLC | 0.04% | Add +248.1% | 59,463 | $1.4M |
| Schroder Investment Management Group | 0.00% | New | 55,015 | $1.3M |
| Affinity Asset Advisors, LLC | 0.09% | Reduce -83.3% | 50,000 | $1.2M |
| Senvest Management, LLC | 0.04% | New | 50,000 | $1.2M |
| WINTON GROUP Ltd | 0.04% | Add +17.6% | 48,185 | $1.2M |
| Stifel Financial Corp. | 0.00% | Reduce -21.1% | 45,987 | $1.1M |
| Y-Intercept (Hong Kong) Ltd | 0.02% | Add +101.6% | 45,778 | $1.1M |
| Diadema Partners LP | 0.64% | New | 45,000 | $1.1M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +18.7% | 44,250 | $1.1M |
| Stempoint Capital LP | 0.18% | Reduce -91.7% | 43,485 | $1.0M |
| Engineers Gate Manager LP | 0.01% | New | 43,356 | $1.0M |
| Bank of New York Mellon Corp | 0.00% | Add +95.0% | 43,309 | $1.0M |
| Tejara Capital Ltd | 0.42% | New | 42,000 | $1.0M |
| Shay Capital LLC | 0.16% | Add +17.4% | 41,073 | $983K |
| Massar Capital Management, LP | 0.19% | Add +102.7% | 40,529 | $970K |
| Headlands Technologies LLC | 0.08% | Reduce -31.0% | 39,616 | $948K |
| PFM Health Sciences, LP | 0.10% | Reduce -14.8% | 39,499 | $945K |
| CI Investments Inc. | 0.00% | Reduce -20.2% | 37,841 | $906K |
| California State Teachers Retirement System | 0.00% | Add +14.8% | 35,947 | $860K |
| MML Investors Services, LLC | 0.00% | New | 33,937 | $812K |
| Diamond Hill Capital Management, LLC (Investment Advisor) | 0.00% | No change | 33,333 | $798K |
| Legal & General Group Plc | 0.00% | Reduce -10.3% | 31,964 | $765K |
| BIT Capital GmbH | 0.03% | New | 31,614 | $757K |
| Birchview Capital, LP | 0.43% | Reduce -60.9% | 30,789 | $737K |
| Sectoral Asset Management Inc. | 0.59% | Reduce -0.5% | 30,585 | $732K |
| Boothbay Fund Management, LLC | 0.02% | Reduce -22.7% | 30,448 | $729K |
| Havemeyer Place LP | 0.14% | — | 29,655 | $710K |
| Pekin Hardy Strauss, Inc. | 0.06% | New | 29,300 | $701K |
| Voya Investment Management LLC | 0.00% | Reduce -71.8% | 28,850 | $690K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | Reduce -2.8% | 28,708 | $687K |
| SummitTX Capital, L.P. | 0.02% | Add +386.3% | 27,708 | $663K |
| DNB Asset Management AS | 0.00% | Add +131.7% | 27,342 | $654K |
| Monimus Capital Management, LP | 0.41% | New | 25,878 | $619K |
| Monaco Asset Management SAM | 0.18% | Reduce -37.4% | 25,000 | $598K |
| Point72 Asset Management | 0.00% | Reduce -90.4% | 24,439 | $585K |
| TD Asset Management Inc | 0.00% | Reduce -75.0% | 23,734 | $568K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -84.2% | 23,707 | $567K |
| LPL Financial LLC | 0.00% | Reduce -52.4% | 21,969 | $526K |
| Marshall Wace, LLP | 0.00% | Reduce -80.5% | 21,159 | $506K |
| J. Goldman & Co LP | 0.02% | New | 20,250 | $485K |
| Voleon Capital Management LP | 0.01% | New | 20,243 | $484K |
| Burkehill Global Management, LP | 0.03% | No change | 20,000 | $479K |
| State of Wisconsin Investment Board | 0.00% | Add +443.4% | 19,390 | $464K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -4.5% | 19,007 | $455K |
| Assetmark, Inc. | 0.00% | New | 18,613 | $445K |
| Clear Harbor Asset Management, LLC | 0.03% | Add +141.4% | 16,900 | $404K |
| Janus Henderson Group PLC | 0.00% | Reduce -15.1% | 16,900 | $404K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -66.2% | 16,462 | $391K |
| Qsemble Capital Management, LP | 0.03% | New | 15,931 | $381K |
| Prelude Capital Management, LLC | 0.03% | Add +29.4% | 15,739 | $377K |
| Nomura Holdings Inc. | 0.00% | New | 15,584 | $373K |
| Handelsbanken Fonder AB | 0.00% | New | 14,900 | $357K |
| Lion Point Capital, LP | 1.82% | New | 14,700 | $352K |
| Farallon Capital Management, L.L.C. | 0.00% | Reduce -97.5% | 14,000 | $335K |
| Sei Investments Co. | 0.00% | Reduce -79.3% | 13,938 | $333K |
| Virtus Investment Advisers, LLC | 0.09% | Add +91.6% | 13,636 | $326K |
| Lido Advisors, LLC | 0.00% | No change | 5,544 | $324K |
| FORA Capital, LLC | 0.04% | New | 13,313 | $319K |
| Freestone Grove Partners LP | 0.00% | New | 12,984 | $311K |
| Lighthouse Investment Partners, LLC | 0.01% | New | 12,500 | $299K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -0.7% | 12,356 | $296K |
| Vontobel Holding Ltd. | 0.00% | New | 11,933 | $286K |
| Diametric Capital, LP | 0.08% | Add +119.6% | 11,822 | $283K |
| Arizona State Retirement System | 0.00% | Add +6.0% | 11,141 | $267K |
| Persistent Asset Partners Ltd | 0.13% | New | 11,014 | $264K |
| Orion Porfolio Solutions, LLC | 0.00% | New | 10,768 | $258K |
| Sassicaia Capital Advisers LLC | 0.55% | Reduce -35.0% | 10,400 | $249K |
| Scientech Research LLC | 0.15% | Reduce -65.2% | 10,203 | $244K |
| China Universal Asset Management Co., Ltd. | 0.02% | Add +5.5% | 10,150 | $243K |
| Ashford Capital Management Inc. | 0.03% | New | 10,000 | $239K |
| Quinn Opportunity Partners LLC | 0.01% | Reduce -90.7% | 10,000 | $239K |
| Pavaki Capital Management LLC | 0.16% | — | 9,810 | $235K |
| Graham Capital Management, L.P. | 0.01% | New | 9,013 | $216K |
| Seven Fleet Capital Management LP | 0.14% | — | 8,742 | $209K |
| Rangeley Capital, LLC | 0.18% | New | 8,500 | $203K |
| Militia Capital Partners, LP | 0.08% | Reduce -75.7% | 8,500 | $203K |
| Mraz, Amerine & Associates, Inc. | 0.03% | Reduce -8.8% | 8,495 | $203K |
| KLP Kapitalforvaltning As | 0.00% | No change | 8,400 | $201K |
| Cetera Investment Advisers | 0.00% | New | 8,366 | $200K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | Reduce -47.6% | 8,098 | $189K |
| Walleye Trading LLC | 0.00% | Reduce -83.8% | 7,657 | $183K |
| US Bancorp \de | 0.00% | Add +775.3% | 6,171 | $148K |
| Quantbot Technologies LP | 0.00% | New | 5,444 | $130K |
| Activest Wealth Management | 0.02% | No change | 5,000 | $120K |
| Bellevue Group AG | 0.00% | No change | 4,763 | $114K |
| Deutsche Bank AG | 0.00% | Add +98.3% | 4,621 | $111K |
| Knott David M Jr | 0.04% | Add +100.0% | 4,000 | $96K |
| Ensign Peak Advisors, Inc | 0.00% | Add +21.7% | 3,650 | $87K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +42.7% | 3,027 | $72K |
| FNY Investment Advisers, LLC | 0.01% | Add +25.8% | 2,080 | $49K |
| IFP Advisors, Inc | 0.00% | New | 1,989 | $48K |
| Smartleaf Asset Management LLC | 0.00% | New | 2,000 | $48K |
| GF Fund Management Co. LTD. | 0.00% | Add +3.6% | 1,223 | $29K |
| Torren Management, LLC | 0.01% | — | 1,169 | $28K |
| CIBC Private Wealth Group LLC | 0.00% | No change | 850 | $20K |
| Parallel Advisors, LLC | 0.00% | New | 848 | $20K |
| Comerica Bank | 0.00% | Add +56.5% | 637 | $15K |
| Osaic Holdings, Inc. | 0.00% | Add +428.8% | 587 | $14K |
| Jones Financial Companies LLLP | 0.00% | Reduce -31.4% | 418 | $10K |
| Cygnus Capital Advisors, LLC | 0.01% | — | 288 | $7K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -75.4% | 280 | $7K |
| Cwm, LLC | 0.00% | No change | 247 | $6K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 250 | $6K |
| Signaturefd, LLC | 0.00% | No change | 249 | $6K |
| Rockefeller Capital Management L.P. | 0.00% | Reduce -75.3% | 247 | $6K |
| UMB Bank, n.a. | 0.00% | No change | 200 | $5K |
| Entrust Financial LLC | 0.00% | — | 190 | $5K |
| Quadrant Capital Group LLC | 0.00% | No change | 187 | $4K |
| Allworth Financial LP | 0.00% | No change | 174 | $4K |
| Daiwa Securities Group Inc. | 0.00% | No change | 158 | $4K |
| State of Wyoming | 0.00% | New | 161 | $4K |
| Farther Finance Advisors, LLC | 0.00% | New | 114 | $3K |
| ORG Partners LLC | 0.00% | New | 114 | $3K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 109 | $3K |
| Toth Financial Advisory Corp. | 0.00% | Reduce -39.4% | 100 | $2K |
| Basecamp Wealth Advisors LLC | 0.00% | — | 91 | $2K |
| Versant Capital Management, Inc | 0.00% | Reduce -48.5% | 85 | $2K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -92.7% | 76 | $2K |
| Transamerica Financial Advisors, LLC | 0.00% | New | 71 | $2K |
| Global Retirement Partners, LLC | 0.00% | Reduce -77.7% | 67 | $2K |
| Greenline Wealth Management LLC | 0.00% | — | 52 | $1K |
| Motiv8 Investments LLC | 0.00% | New | 45 | $1K |
| Cape Investment Advisory, Inc. | 0.00% | New | 40 | $957 |
| Cullen/Frost Bankers, Inc. | 0.00% | New | 34 | $814 |
| MAI Capital Management | 0.00% | Add +154.6% | 28 | $671 |
| CoreCap Advisors, LLC | 0.00% | New | 19 | $455 |
| WPG Advisers, LLC | 0.00% | Reduce -94.9% | 10 | $239 |
| Larson Financial Group LLC | 0.00% | No change | 8 | $191 |
| GAMMA Investing LLC | 0.00% | Add +100.0% | 8 | $191 |
| Arax Advisory Partners | 0.00% | Reduce -91.0% | 6 | $144 |
| Montag A & Associates Inc. | 0.00% | New | 5 | $118 |
| First Horizon Corp. | 0.00% | Reduce -99.2% | 3 | $72 |
| Northwestern Mutual Wealth Management Co. | 0.00% | New | 3 | $72 |
| Huntington National Bank | 0.00% | No change | 2 | $48 |
| Lanark Financial, Inc. | 0.00% | New | 2 | $47 |
"% of holder's portfolio" is QURE's weight in each manager's 13F, not the share of Uniqure NV the manager owns.