Xenon PharmaceuticalsXENE
13F holders, Q3 2024 (September 30)At the end of Q3 2024, 203 institutions reported holding Xenon Pharmaceuticals Inc. (XENE) in their 13F filings, down 10 from Q2 2024. 13 opened new positions and 24 sold out. The largest holders were FMR LLC ($272.3M), Avoro Capital Advisors LLC ($223.1M) and Driehaus Capital Management LLC ($180.9M). 7 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Xenon Pharmaceuticals Inc.
- CUSIP
- 98420N105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2024 → Q3 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 13 | $15.5M |
| Exits | 24 | $139.3M |
All 13F filers, Q2 2024 → Q3 2024: 5,797,892 shares bought and 5,831,391 shares sold, net −33,499 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 203 holders
| FMR LLC | 0.02% | Add +2.2% | 6,917,684 | $272.3M |
| Avoro Capital Advisors LLC | 3.25% | No change | 5,666,666 | $223.1M |
| Driehaus Capital Management LLC | 1.55% | Add +4.0% | 4,595,721 | $180.9M |
| Wellington Management Group LLP | 0.03% | Add +0.4% | 3,843,447 | $151.3M |
| Braidwell LP | 4.59% | Add +5.7% | 2,707,255 | $106.6M |
| Commodore Capital LP | 6.64% | Reduce -2.0% | 2,700,000 | $106.3M |
| Capital World Investors | 0.02% | No change | 2,681,537 | $105.6M |
| Capital International Investors | 0.02% | Add +4.3% | 2,581,172 | $101.6M |
| Janus Henderson Group PLC | 0.05% | Add +144.2% | 2,552,392 | $100.5M |
| Polar Capital Holdings Plc | 0.46% | Reduce -3.6% | 2,444,645 | $96.2M |
| BlackRock, Inc. | 0.00% | — | 2,105,562 | $82.9M |
| Adage Capital Partners Gp, L.L.C. | 0.14% | Add +13.3% | 2,083,972 | $82.0M |
| Pictet Asset Management Holding SA | 0.07% | Add +3.3% | 1,528,814 | $60.2M |
| T. Rowe Price Investment Management, Inc. | 0.04% | Add +4.4% | 1,503,808 | $59.2M |
| Alliancebernstein L.P. | 0.02% | Reduce -3.9% | 1,424,735 | $56.1M |
| Rock Springs Capital Management LP | 1.69% | Add +3.4% | 1,316,477 | $51.8M |
| Marshall Wace, LLP | 0.06% | Reduce -13.7% | 1,195,480 | $47.1M |
| First Light Asset Management, LLC | 3.87% | Reduce -9.5% | 1,181,662 | $46.5M |
| Affinity Asset Advisors, LLC | 7.49% | Add +15.1% | 1,144,021 | $45.0M |
| Samlyn Capital, LLC | 0.65% | Add +59.5% | 1,020,206 | $40.2M |
| Baker Bros. Advisors LP | 0.41% | No change | 993,679 | $39.1M |
| JPMorgan Chase & Co. | 0.00% | Add +1263.2% | 976,783 | $38.5M |
| Orbimed Advisors LLC | 0.66% | Add +5.7% | 911,420 | $35.9M |
| Vestal Point Capital, LP | 2.56% | Add +57.1% | 825,000 | $32.5M |
| Avidity Partners Management LP | 1.64% | Add +8.5% | 818,000 | $32.2M |
| TimesSquare Capital Management, LLC | 0.46% | Add +3.1% | 778,293 | $30.6M |
| Siren, L.L.C. | 1.47% | — | 743,769 | $29.3M |
| Federated Hermes, Inc. | 0.06% | Add +0.2% | 736,200 | $29.0M |
| Citadel Advisors | 0.03% | Reduce -6.0% | 722,504 | $28.4M |
| Loomis Sayles & Co. L P | 0.04% | Add +7.1% | 707,222 | $27.8M |
| Westfield Capital Management Co. LP | 0.12% | Add +4.0% | 669,600 | $26.4M |
| Franklin Resources Inc. | 0.01% | Reduce -2.2% | 565,915 | $23.6M |
| Boxer Capital, LLC | 1.16% | No change | 600,000 | $23.6M |
| Jennison Associates LLC | 0.01% | Add +1.1% | 576,661 | $22.7M |
| Fiera Capital Corp | 0.07% | Reduce -4.9% | 554,200 | $21.8M |
| Perceptive Advisors LLC | 0.44% | Reduce -10.0% | 524,930 | $20.7M |
| Candriam S.C.A. | 0.11% | Reduce -11.1% | 463,861 | $18.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +26.2% | 459,625 | $18.1M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.04% | Add +4.3% | 439,074 | $17.3M |
| Point72 Asset Management | 0.05% | Reduce -20.5% | 383,290 | $15.1M |
| Altium Capital Management LLC | 4.24% | No change | 360,600 | $14.2M |
| Vanguard Group Inc. | 0.00% | Add +0.9% | 344,365 | $13.6M |
| First Turn Management, LLC | 2.03% | Reduce -4.3% | 325,218 | $12.8M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -31.3% | 299,865 | $11.8M |
| Alyeska Investment Group, L.P. | 0.06% | Reduce -1.0% | 288,843 | $11.4M |
| State Street Corp. | 0.00% | Add +13.3% | 279,513 | $11.0M |
| DAFNA Capital Management LLC | 2.57% | No change | 273,739 | $10.8M |
| Two Sigma Advisers, LP | 0.03% | Add +31.0% | 273,700 | $10.8M |
| ExodusPoint Capital Management, LP | 0.11% | Reduce -26.5% | 262,631 | $10.3M |
| Aberdeen Group plc | 0.02% | Add +16.9% | 248,311 | $9.8M |
| Two Sigma Investments, LP | 0.02% | Add +24.8% | 243,579 | $9.6M |
| Morgan Stanley | 0.00% | Add +0.5% | 239,942 | $9.4M |
| Russell Investments Group, Ltd. | 0.01% | Add +37.3% | 223,614 | $8.8M |
| Algert Global LLC | 0.23% | Add +19.9% | 219,645 | $8.6M |
| Invesco Ltd. | 0.00% | Reduce -75.1% | 215,822 | $8.5M |
| Assenagon Asset Management S.A. | 0.02% | Add +188.4% | 212,287 | $8.4M |
| Ally Bridge Group (NY) LLC | 4.46% | Add +25.1% | 211,791 | $8.3M |
| Millennium Management | 0.01% | Add +19.1% | 209,026 | $8.2M |
| D. E. Shaw & Co. | 0.01% | Add +26.7% | 204,892 | $8.1M |
| Granahan Investment Management, LLC | 0.31% | Reduce -11.2% | 200,877 | $7.9M |
| Parkman Healthcare Partners LLC | 0.96% | Reduce -8.4% | 191,658 | $7.5M |
| DNB Asset Management AS | 0.03% | Add +8.5% | 190,623 | $7.5M |
| AXA S.A. | 0.02% | Add +0.0% | 188,090 | $7.4M |
| PFM Health Sciences, LP | 0.41% | Add +19.5% | 179,878 | $7.1M |
| Lord, Abbett & Co. LLC | 0.02% | Reduce -8.4% | 173,985 | $6.8M |
| Schroder Investment Management Group | 0.01% | Add +93.1% | 176,674 | $6.8M |
| MPM Bioimpact LLC | 0.98% | New | 165,800 | $6.5M |
| Ensign Peak Advisors, Inc | 0.01% | No change | 163,064 | $6.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.1% | 162,683 | $6.4M |
| Bridger Management, LLC | 2.89% | No change | 146,800 | $5.8M |
| New York State Common Retirement Fund | 0.01% | Reduce -12.1% | 132,521 | $5.2M |
| Bank of America Corp. | 0.00% | Reduce -10.4% | 127,456 | $5.0M |
| Atika Capital Management LLC | 0.53% | Add +1.6% | 126,000 | $5.0M |
| Swiss National Bank | 0.00% | Reduce -0.6% | 125,300 | $4.9M |
| Ikarian Capital, LLC | 1.31% | No change | 107,187 | $4.2M |
| Nan Fung Group Holdings Ltd | 3.62% | No change | 106,680 | $4.2M |
| Walleye Capital LLC | 0.05% | New | 104,960 | $4.1M |
| State of Wisconsin Investment Board | 0.01% | Add +12.4% | 100,982 | $4.0M |
| Baron Capital (BAMCO) | 0.01% | No change | 100,100 | $3.9M |
| Balyasny Asset Management L.P. | 0.01% | Reduce -63.9% | 84,198 | $3.3M |
| HighVista Strategies LLC | 1.00% | Add +1.4% | 73,762 | $2.9M |
| Geode Capital Management, LLC | 0.00% | Reduce -0.2% | 68,809 | $2.7M |
| Jefferies Financial Group Inc. | 0.05% | Reduce -3.6% | 66,500 | $2.6M |
| Ameriprise Financial Inc. | 0.00% | New | 66,383 | $2.6M |
| Wells Fargo & Company | 0.00% | Add +2.4% | 60,456 | $2.4M |
| Alps Advisors Inc. | 0.01% | Reduce -3.2% | 56,989 | $2.2M |
| California State Teachers Retirement System | 0.00% | Reduce -3.7% | 56,004 | $2.2M |
| Legal & General Group Plc | 0.00% | No change | 55,120 | $2.2M |
| Moore Capital Management, LP | 0.07% | No change | 55,000 | $2.2M |
| Deutsche Bank AG | 0.00% | No change | 53,711 | $2.1M |
| Erste Asset Management GmbH | 0.02% | No change | 50,000 | $1.9M |
| Bank of New York Mellon Corp | 0.00% | Reduce -4.6% | 48,891 | $1.9M |
| Envestnet Asset Management Inc. | 0.00% | Reduce -0.2% | 48,836 | $1.9M |
| LMR Partners LLP | 0.05% | No change | 48,668 | $1.9M |
| State of New Jersey Common Pension Fund D | 0.01% | No change | 48,573 | $1.9M |
| Harbor Capital Advisors, Inc. | 0.08% | Add +99.3% | 48,063 | $1.9M |
| Voya Investment Management LLC | 0.00% | No change | 47,165 | $1.9M |
| Jump Financial, LLC | 0.04% | Reduce -6.6% | 45,000 | $1.8M |
| Renaissance Technologies | 0.00% | Reduce -52.6% | 44,000 | $1.7M |
| Northern Trust Corp. | 0.00% | Reduce -7.4% | 43,406 | $1.7M |
| Thrivent Financial for Lutherans | 0.00% | No change | 43,093 | $1.7M |
| Skandinaviska Enskilda Banken AB (publ) | 0.01% | No change | 40,376 | $1.6M |
| Artia Global Partners LP | 0.45% | No change | 40,000 | $1.6M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 39,000 | $1.5M |
| Royal Bank of Canada | 0.00% | Add +3.4% | 37,636 | $1.5M |
| Gsa Capital Partners LLP | 0.11% | Add +475.9% | 37,308 | $1.5M |
| Tudor Investment Corporation | 0.02% | Add +45.4% | 36,687 | $1.4M |
| Rhenman & Partners Asset Management AB | 0.11% | No change | 35,000 | $1.4M |
| TLS Advisors LLC | 2.74% | No change | 32,956 | $1.3M |
| Boothbay Fund Management, LLC | 0.04% | No change | 30,145 | $1.2M |
| HRT Financial LP | 0.01% | Reduce -13.3% | 29,641 | $1.2M |
| ADAR1 Capital Management, LLC | 0.18% | Add +493.7% | 27,903 | $1.1M |
| Natixis Advisors, LLC | 0.00% | Add +38.6% | 27,158 | $1.1M |
| NJ State Employees Deferred Compensation Plan | 0.12% | No change | 25,000 | $984K |
| Y-Intercept (Hong Kong) Ltd | 0.06% | Add +68.8% | 24,557 | $967K |
| Nebula Research & Development LLC | 0.11% | Reduce -19.6% | 24,265 | $955K |
| Rathbones Group PLC | 0.00% | No change | 23,666 | $932K |
| Handelsbanken Fonder AB | 0.00% | Add +8.1% | 22,700 | $894K |
| Stifel Financial Corp. | 0.00% | Reduce -2.3% | 21,571 | $849K |
| Sanders Morris Harris LLC | 0.14% | No change | 21,500 | $846K |
| Knott David M Jr | 0.29% | No change | 20,866 | $821K |
| TD Asset Management Inc | 0.00% | No change | 20,430 | $790K |
| Cibc World Market Inc. | 0.00% | Reduce -45.5% | 19,835 | $781K |
| Fox Run Management, L.L.C. | 0.17% | Add +195.3% | 19,744 | $777K |
| Assetmark, Inc. | 0.00% | Add +7.9% | 19,670 | $774K |
| Arizona State Retirement System | 0.00% | Add +2.9% | 18,472 | $727K |
| Prelude Capital Management, LLC | 0.06% | Reduce -0.4% | 18,266 | $719K |
| Chartwell Investment Partners, LLC | 0.02% | Add +0.8% | 18,213 | $717K |
| Trexquant Investment LP | 0.01% | Reduce -58.6% | 16,907 | $666K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -0.1% | 16,408 | $646K |
| Teacher Retirement System of Texas | 0.00% | Add +14.3% | 16,089 | $633K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 15,911 | $628K |
| Barclays PLC | 0.00% | Add +1275.5% | 14,993 | $590K |
| Nicholas Investment Partners, LP | 0.06% | New | 14,658 | $577K |
| China Universal Asset Management Co., Ltd. | 0.06% | Add +64.3% | 14,572 | $574K |
| Orion Porfolio Solutions, LLC | 0.01% | Reduce -0.1% | 14,503 | $571K |
| Orion Portfolio Solutions, LLC | 0.01% | Reduce -0.1% | 14,503 | $571K |
| Prudential Financial Inc. | 0.00% | Reduce -73.0% | 14,044 | $553K |
| Advisors Asset Management, Inc. | 0.01% | Add +3.8% | 13,592 | $535K |
| Schonfeld Strategic Advisors LLC | 0.00% | Reduce -57.9% | 13,582 | $535K |
| UBS Group AG | 0.00% | Add +5.7% | 13,290 | $523K |
| Brevan Howard Capital Management LP | 0.02% | New | 12,012 | $473K |
| Supplemental Annuity Collective Trust of NJ | 0.13% | No change | 11,000 | $433K |
| Occudo Quantitative Strategies LP | 0.08% | New | 10,811 | $426K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 10,633 | $419K |
| Guggenheim Capital LLC | 0.00% | Reduce -5.8% | 10,629 | $418K |
| Birchview Capital, LP | 0.34% | No change | 10,000 | $394K |
| Vestcor Inc | 0.01% | New | 8,300 | $327K |
| Bellevue Group AG | 0.01% | Reduce -19.6% | 8,200 | $323K |
| Allianz Asset Management GmbH | 0.00% | Reduce -26.4% | 8,100 | $319K |
| PEAK6 Investments LLC | 0.02% | No change | 8,000 | $315K |
| SG Americas Securities, LLC | 0.00% | Reduce -70.5% | 7,716 | $304K |
| Elmwood Wealth Management, Inc. | 0.12% | Reduce -4.2% | 7,607 | $299K |
| Squarepoint Ops LLC | 0.00% | New | 7,504 | $295K |
| Aigen Investment Management, LP | 0.06% | Reduce -21.0% | 7,370 | $290K |
| Campbell & CO Investment Adviser LLC | 0.02% | Reduce -69.5% | 7,339 | $289K |
| Qube Research & Technologies Ltd | 0.00% | Reduce -85.5% | 6,938 | $273K |
| Engineers Gate Manager LP | 0.00% | Reduce -81.0% | 5,581 | $220K |
| Oppenheimer Asset Management Inc. | 0.00% | Reduce -1.4% | 5,306 | $209K |
| HighMark Wealth Management LLC | 0.11% | No change | 5,000 | $197K |
| Northwestern Mutual Wealth Management Co. | 0.00% | No change | 5,000 | $197K |
| PNC Financial Services Group, Inc. | 0.00% | Add +2.5% | 4,960 | $195K |
| Citigroup Inc. | 0.00% | Reduce -5.0% | 3,648 | $144K |
| BNP Paribas Financial Markets | 0.00% | Reduce -70.1% | 3,472 | $137K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +21.6% | 2,740 | $106K |
| nVerses Capital, LLC | 0.05% | New | 2,600 | $102K |
| Virtus Advisers, LLC | 0.04% | Add +1.9% | 2,425 | $95K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -75.5% | 2,019 | $79K |
| Concourse Financial Group Securities, Inc. | 0.00% | No change | 2,000 | $79K |
| IFP Advisors, Inc | 0.00% | Reduce -6.0% | 1,977 | $78K |
| KBC Group NV | 0.00% | No change | 1,962 | $77K |
| Blue Trust, Inc. | 0.00% | Add +174.7% | 1,008 | $39K |
| US Bancorp \de | 0.00% | Reduce -6.9% | 606 | $24K |
| State of Wyoming | 0.00% | Add +85.0% | 544 | $21K |
| Osaic Holdings, Inc. | 0.00% | Reduce -14.5% | 459 | $18K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +488.7% | 418 | $16K |
| Accent Capital Management, LLC | 0.01% | No change | 400 | $16K |
| Parallel Advisors, LLC | 0.00% | Reduce -67.1% | 381 | $15K |
| First Horizon Advisors, Inc. | 0.00% | No change | 370 | $15K |
| Daiwa Securities Group Inc. | 0.00% | Add +14.3% | 288 | $11K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 276 | $11K |
| Signaturefd, LLC | 0.00% | Add +83.7% | 237 | $9K |
| National Bank of Canada | 0.00% | No change | 235 | $9K |
| Lindbrook Capital, LLC | 0.00% | Reduce -29.1% | 229 | $9K |
| Clearstead Advisors, LLC | 0.00% | No change | 218 | $9K |
| Group One Trading LLC | 0.00% | Add +2500.0% | 104 | $4K |
| Summit Securities Group LLC | 0.00% | New | 90 | $4K |
| Danske Bank A/S | 0.00% | New | 100 | $4K |
| Bell Investment Advisors, Inc | 0.00% | No change | 64 | $3K |
| Wolff Wiese Magana LLC | 0.00% | New | 61 | $2K |
| GAMMA Investing LLC | 0.00% | Add +55.3% | 59 | $2K |
| Principal Securities, Inc. | 0.00% | Add +114.3% | 45 | $2K |
| Whittier Trust Co. of Nevada Inc. | 0.00% | No change | 36 | $1K |
| Point72 (DIFC) Ltd | 0.00% | Reduce -89.3% | 34 | $1K |
| CVA Family Office, LLC | 0.00% | No change | 33 | $1K |
| Rhumbline Advisers | 0.00% | No change | 29 | $1K |
| Continuum Advisory, LLC | 0.00% | Add +80.0% | 27 | $1K |
| Cwm, LLC | 0.00% | Add +100.0% | 14 | $1K |
| Park Place Capital Corp | 0.00% | No change | 18 | $709 |
| Allworth Financial LP | 0.00% | Add +140.0% | 12 | $473 |
| J.Safra Asset Management Corp | 0.00% | New | 11 | $425 |
| C M Bidwell & Associates Ltd. | 0.00% | No change | 9 | $354 |
| Arax Advisory Partners | 0.00% | No change | 3 | $119 |
"% of holder's portfolio" is XENE's weight in each manager's 13F, not the share of Xenon Pharmaceuticals Inc. the manager owns.