Ionis PharmaceuticalsIONS
13F holders, Q2 2024 (June 30)At the end of Q2 2024, 357 institutions reported holding Ionis Pharmaceuticals Inc. (IONS) in their 13F filings, down 4 from Q1 2024. 48 opened new positions and 53 sold out. The largest holders were FMR LLC ($1.0B), Vanguard Group Inc. ($659.9M) and T. Rowe Price Investment Management, Inc. ($602.4M). 8 famous investors held it, including Cathie Wood (0.6% of ARK Investment Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Ionis Pharmaceuticals Inc.
- CUSIP
- 462222100
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2024 → Q2 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 48 | $135.7M |
| Exits | 53 | $63.3M |
All 13F filers, Q1 2024 → Q2 2024: 13,822,232 shares bought and 12,772,635 shares sold, net +1,049,597 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 357 holders
| FMR LLC | 0.07% | Add +0.1% | 21,894,806 | $1.0B |
| Vanguard Group Inc. | 0.01% | Add +3.1% | 13,845,712 | $659.9M |
| T. Rowe Price Investment Management, Inc. | 0.38% | Reduce -5.1% | 12,639,684 | $602.4M |
| BlackRock Inc. | 0.01% | Add +5.6% | 10,321,030 | $491.9M |
| Bellevue Group AG | 6.40% | Reduce -0.5% | 8,260,434 | $393.7M |
| Wellington Management Group LLP | 0.06% | Add +15.3% | 6,568,808 | $313.1M |
| State Street Corp. | 0.01% | Add +0.8% | 4,190,505 | $199.7M |
| T. Rowe Price Associates Inc. | 0.02% | Add +11.7% | 3,934,311 | $187.5M |
| Tweedy, Browne Co LLC | 7.57% | No change | 3,454,676 | $164.6M |
| BVF Inc. | 4.26% | Add +31.2% | 3,186,376 | $151.9M |
| Geode Capital Management, LLC | 0.01% | Add +5.1% | 2,484,544 | $118.4M |
| Pictet Asset Management Holding SA | 0.13% | Reduce -35.6% | 2,409,954 | $114.9M |
| Orbimed Advisors LLC | 2.25% | Add +17.9% | 2,372,333 | $113.1M |
| Capital World Investors | 0.02% | Add +168.3% | 2,252,089 | $107.3M |
| Clearbridge Investments, LLC | 0.08% | Reduce -51.6% | 2,160,270 | $103.0M |
| Deep Track Capital, LP | 2.85% | Add +45.6% | 2,000,000 | $95.3M |
| Macquarie Group Ltd. | 0.10% | Reduce -41.5% | 1,873,668 | $89.3M |
| Artisan Partners Limited Partnership | 0.12% | Add +301.0% | 1,671,036 | $79.6M |
| ARK Investment Management | 0.58% | Reduce -2.8% | 1,361,025 | $64.9M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +2.0% | 1,328,106 | $63.3M |
| Two Sigma Advisers, LP | 0.14% | Add +23.8% | 1,287,111 | $61.3M |
| Balyasny Asset Management L.P. | 0.14% | New | 1,077,321 | $51.3M |
| Two Sigma Investments, LP | 0.12% | Reduce -5.1% | 1,028,142 | $49.0M |
| Norges Bank | 0.01% | Reduce -17.6% | 1,019,341 | $48.6M |
| Morgan Stanley | 0.00% | Reduce -13.0% | 1,012,805 | $48.3M |
| Invesco Ltd. | 0.01% | Add +118.8% | 968,917 | $46.2M |
| TD Asset Management Inc | 0.04% | Add +6.1% | 952,762 | $45.4M |
| Candriam S.C.A. | 0.28% | Add +4.0% | 948,266 | $45.2M |
| Adage Capital Partners Gp, L.L.C. | 0.07% | Reduce -20.0% | 800,000 | $38.1M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.10% | Add +0.3% | 780,753 | $37.2M |
| Schonfeld Strategic Advisors LLC | 0.27% | Add +323.5% | 723,618 | $34.5M |
| Northern Trust Corp. | 0.01% | Add +3.7% | 717,975 | $34.2M |
| Royal Bank of Canada | 0.01% | Reduce -7.4% | 678,360 | $32.3M |
| Man Group plc | 0.08% | Add +150.1% | 633,409 | $30.2M |
| Citadel Advisors | 0.03% | Add +703.6% | 627,033 | $29.9M |
| Barclays PLC | 0.01% | Add +6.6% | 615,674 | $29.3M |
| Bank of New York Mellon Corp | 0.01% | Add +2.4% | 597,479 | $28.5M |
| JPMorgan Chase & Co. | 0.00% | Reduce -5.8% | 594,091 | $28.3M |
| Jacobs Levy Equity Management, Inc. | 0.11% | Add +0.2% | 572,870 | $27.3M |
| Bank of America Corp. | 0.00% | Reduce -15.1% | 514,543 | $24.5M |
| Nomura Holdings Inc. | 0.15% | Add +6.5% | 501,188 | $23.9M |
| AXA S.A. | 0.07% | Add +0.0% | 464,963 | $22.2M |
| Eversept Partners, LP | 1.67% | Add +21.4% | 456,881 | $21.8M |
| Pinnacle Associates Ltd. | 0.34% | Reduce -1.4% | 453,379 | $21.6M |
| Squarepoint Ops LLC | 0.08% | Reduce -41.4% | 436,818 | $20.8M |
| Nuveen Asset Management, LLC | 0.01% | Reduce -3.0% | 410,404 | $19.6M |
| Groupama Asset Managment | 0.25% | Add +47.4% | 379,976 | $18.1M |
| Wells Fargo & Company | 0.00% | Reduce -37.3% | 366,561 | $17.5M |
| Hudson Bay Capital Management LP | 0.15% | Add +9.1% | 366,000 | $17.4M |
| Great Point Partners LLC | 3.01% | New | 330,000 | $15.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +63.8% | 328,305 | $15.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +71.9% | 320,290 | $15.3M |
| Logos Global Management LP | 1.65% | New | 300,000 | $14.3M |
| C WorldWide Group Holding A/S | 0.15% | No change | 300,000 | $14.3M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +12.2% | 274,850 | $13.1M |
| Corient Private Wealth LP | 0.02% | Add +0.3% | 268,037 | $12.8M |
| Baillie Gifford & Co. | 0.01% | Reduce -12.0% | 260,254 | $12.4M |
| Swiss National Bank | 0.01% | Add +1.2% | 258,000 | $12.3M |
| Kennedy Capital Management LLC | 0.26% | Add +1.9% | 254,343 | $12.1M |
| Integral Health Asset Management, LLC | 1.19% | New | 250,000 | $11.9M |
| Renaissance Technologies | 0.02% | Add +38.8% | 249,514 | $11.9M |
| Aberdeen Group plc | 0.02% | Add +12.5% | 246,917 | $11.8M |
| Privium Fund Management B.V. | 3.12% | Add +8.9% | 247,267 | $11.2M |
| Tocqueville Asset Management L.P. | 0.18% | Add +41.2% | 225,070 | $10.7M |
| Bank of Montreal | 0.00% | Reduce -1.0% | 220,518 | $10.5M |
| Orion Investment Co | 4.15% | — | 218,570 | $10.4M |
| Stifel Financial Corp. | 0.01% | Reduce -10.9% | 216,140 | $10.3M |
| New York State Common Retirement Fund | 0.01% | Add +62.5% | 215,716 | $10.3M |
| ExodusPoint Capital Management, LP | 0.11% | Reduce -3.1% | 209,194 | $10.0M |
| Zimmer Partners, LP | 0.18% | Reduce -26.0% | 200,000 | $9.5M |
| Amova Asset Management Americas, Inc. | 0.11% | Reduce -9.6% | 199,231 | $9.5M |
| Sumitomo Mitsui Trust Group, Inc. | 0.01% | Reduce -9.6% | 199,231 | $9.5M |
| California Public Employees Retirement System | 0.01% | Reduce -3.7% | 196,484 | $9.4M |
| Sicart Associates LLC | 3.50% | Reduce -1.3% | 191,523 | $9.1M |
| D. E. Shaw & Co. | 0.01% | Add +18.9% | 190,781 | $9.1M |
| Altrinsic Global Advisors LLC | 0.40% | Reduce -3.6% | 187,831 | $9.0M |
| BNP Paribas Financial Markets | 0.01% | Reduce -4.3% | 185,944 | $8.9M |
| Jane Street Group, LLC | 0.01% | Add +51.7% | 179,246 | $8.5M |
| Rhumbline Advisers | 0.01% | Reduce -0.7% | 178,089 | $8.5M |
| Marshall Wace, LLP | 0.01% | Add +1021.5% | 173,199 | $8.3M |
| Sector Gamma As | 3.03% | Reduce -3.1% | 170,000 | $8.1M |
| Rafferty Asset Management, LLC | 0.03% | Reduce -19.0% | 168,856 | $8.0M |
| Parkman Healthcare Partners LLC | 1.05% | Add +14.3% | 161,705 | $7.7M |
| Cutter Capital Management, LP | 2.33% | Reduce -44.6% | 160,166 | $7.6M |
| Caption Management, LLC | 0.82% | New | 160,000 | $7.6M |
| HRT Financial LP | 0.04% | Add +140.1% | 159,685 | $7.6M |
| BLB&B Advisors, LLC | 0.40% | Add +5.2% | 153,750 | $7.3M |
| UBS Group AG | 0.00% | Reduce -11.1% | 152,672 | $7.3M |
| State Board of Administration of Florida Retirement System | 0.01% | Reduce -2.6% | 151,055 | $7.2M |
| Tang Capital Management LLC | 0.73% | No change | 150,000 | $7.1M |
| Legal & General Group Plc | 0.00% | Reduce -1.2% | 147,644 | $7.0M |
| Sphera Funds Management LTD. | 1.09% | New | 140,238 | $6.7M |
| Point72 Asset Management | 0.02% | Reduce -52.1% | 137,210 | $6.5M |
| Sonora Investment Management Group, LLC | 0.52% | No change | 150,814 | $6.5M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -13.5% | 132,736 | $6.3M |
| Sei Investments Co. | 0.01% | Add +65.6% | 132,311 | $6.3M |
| Peregrine Capital Management LLC | 0.18% | Add +11.3% | 132,024 | $6.3M |
| Rhenman & Partners Asset Management AB | 0.59% | New | 130,000 | $6.2M |
| Swedbank AB | 0.01% | Reduce -9.3% | 129,373 | $6.2M |
| California State Teachers Retirement System | 0.01% | Reduce -2.0% | 129,216 | $6.2M |
"% of holder's portfolio" is IONS's weight in each manager's 13F, not the share of Ionis Pharmaceuticals Inc. the manager owns.