Ionis PharmaceuticalsIONS

13F holders, Q2 2024 (June 30)
357holders −4
48new positions
53sold out
8famous investors
$47.66avg. 13F price*

At the end of Q2 2024, 357 institutions reported holding Ionis Pharmaceuticals Inc. (IONS) in their 13F filings, down 4 from Q1 2024. 48 opened new positions and 53 sold out. The largest holders were FMR LLC ($1.0B), Vanguard Group Inc. ($659.9M) and T. Rowe Price Investment Management, Inc. ($602.4M). 8 famous investors held it, including Cathie Wood (0.6% of ARK Investment Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).

Company
Ionis Pharmaceuticals Inc.
CUSIP
462222100
Latest filing quarter
Q2 2026

History

Number of 13F holders

0200400600 Q1 2024: 361Q1 2024Q2 2024: 357Q2 2024Q3 2024: 354Q3 2024Q4 2024: 355Q4 2024Q1 2025: 344Q1 2025Q2 2025: 362Q2 2025Q3 2025: 436Q3 2025Q4 2025: 494Q4 2025Q1 2026: 497Q1 2026Q2 2026: 515Q2 2026

Total Exit/New Position Q1 2024 → Q2 2024

InstitutionsTotal Value
New Positions48$135.7M
Exits53$63.3M

All 13F filers, Q1 2024 → Q2 2024: 13,822,232 shares bought and 12,772,635 shares sold, net +1,049,597 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 357 holders

FMR LLC 0.07% Add +0.1% 21,894,806 $1.0B
Vanguard Group Inc. 0.01% Add +3.1% 13,845,712 $659.9M
T. Rowe Price Investment Management, Inc. 0.38% Reduce -5.1% 12,639,684 $602.4M
BlackRock Inc. 0.01% Add +5.6% 10,321,030 $491.9M
Bellevue Group AG 6.40% Reduce -0.5% 8,260,434 $393.7M
Wellington Management Group LLP 0.06% Add +15.3% 6,568,808 $313.1M
State Street Corp. 0.01% Add +0.8% 4,190,505 $199.7M
T. Rowe Price Associates Inc. 0.02% Add +11.7% 3,934,311 $187.5M
Tweedy, Browne Co LLC 7.57% No change 3,454,676 $164.6M
BVF Inc. 4.26% Add +31.2% 3,186,376 $151.9M
Geode Capital Management, LLC 0.01% Add +5.1% 2,484,544 $118.4M
Pictet Asset Management Holding SA 0.13% Reduce -35.6% 2,409,954 $114.9M
Orbimed Advisors LLC 2.25% Add +17.9% 2,372,333 $113.1M
Capital World Investors 0.02% Add +168.3% 2,252,089 $107.3M
Clearbridge Investments, LLC 0.08% Reduce -51.6% 2,160,270 $103.0M
Deep Track Capital, LP 2.85% Add +45.6% 2,000,000 $95.3M
Macquarie Group Ltd. 0.10% Reduce -41.5% 1,873,668 $89.3M
Artisan Partners Limited Partnership 0.12% Add +301.0% 1,671,036 $79.6M
ARK Investment Management 0.58% Reduce -2.8% 1,361,025 $64.9M
Charles Schwab Investment Management Inc. 0.01% Add +2.0% 1,328,106 $63.3M
Two Sigma Advisers, LP 0.14% Add +23.8% 1,287,111 $61.3M
Balyasny Asset Management L.P. 0.14% New 1,077,321 $51.3M
Two Sigma Investments, LP 0.12% Reduce -5.1% 1,028,142 $49.0M
Norges Bank 0.01% Reduce -17.6% 1,019,341 $48.6M
Morgan Stanley 0.00% Reduce -13.0% 1,012,805 $48.3M
Invesco Ltd. 0.01% Add +118.8% 968,917 $46.2M
TD Asset Management Inc 0.04% Add +6.1% 952,762 $45.4M
Candriam S.C.A. 0.28% Add +4.0% 948,266 $45.2M
Adage Capital Partners Gp, L.L.C. 0.07% Reduce -20.0% 800,000 $38.1M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.10% Add +0.3% 780,753 $37.2M
Schonfeld Strategic Advisors LLC 0.27% Add +323.5% 723,618 $34.5M
Northern Trust Corp. 0.01% Add +3.7% 717,975 $34.2M
Royal Bank of Canada 0.01% Reduce -7.4% 678,360 $32.3M
Man Group plc 0.08% Add +150.1% 633,409 $30.2M
Citadel Advisors 0.03% Add +703.6% 627,033 $29.9M
Barclays PLC 0.01% Add +6.6% 615,674 $29.3M
Bank of New York Mellon Corp 0.01% Add +2.4% 597,479 $28.5M
JPMorgan Chase & Co. 0.00% Reduce -5.8% 594,091 $28.3M
Jacobs Levy Equity Management, Inc. 0.11% Add +0.2% 572,870 $27.3M
Bank of America Corp. 0.00% Reduce -15.1% 514,543 $24.5M
Nomura Holdings Inc. 0.15% Add +6.5% 501,188 $23.9M
AXA S.A. 0.07% Add +0.0% 464,963 $22.2M
Eversept Partners, LP 1.67% Add +21.4% 456,881 $21.8M
Pinnacle Associates Ltd. 0.34% Reduce -1.4% 453,379 $21.6M
Squarepoint Ops LLC 0.08% Reduce -41.4% 436,818 $20.8M
Nuveen Asset Management, LLC 0.01% Reduce -3.0% 410,404 $19.6M
Groupama Asset Managment 0.25% Add +47.4% 379,976 $18.1M
Wells Fargo & Company 0.00% Reduce -37.3% 366,561 $17.5M
Hudson Bay Capital Management LP 0.15% Add +9.1% 366,000 $17.4M
Great Point Partners LLC 3.01% New 330,000 $15.7M
Goldman Sachs Group Inc. 0.00% Add +63.8% 328,305 $15.6M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +71.9% 320,290 $15.3M
Logos Global Management LP 1.65% New 300,000 $14.3M
C WorldWide Group Holding A/S 0.15% No change 300,000 $14.3M
Manufacturers Life Insurance Company, The 0.01% Add +12.2% 274,850 $13.1M
Corient Private Wealth LP 0.02% Add +0.3% 268,037 $12.8M
Baillie Gifford & Co. 0.01% Reduce -12.0% 260,254 $12.4M
Swiss National Bank 0.01% Add +1.2% 258,000 $12.3M
Kennedy Capital Management LLC 0.26% Add +1.9% 254,343 $12.1M
Integral Health Asset Management, LLC 1.19% New 250,000 $11.9M
Renaissance Technologies 0.02% Add +38.8% 249,514 $11.9M
Aberdeen Group plc 0.02% Add +12.5% 246,917 $11.8M
Privium Fund Management B.V. 3.12% Add +8.9% 247,267 $11.2M
Tocqueville Asset Management L.P. 0.18% Add +41.2% 225,070 $10.7M
Bank of Montreal 0.00% Reduce -1.0% 220,518 $10.5M
Orion Investment Co 4.15% — 218,570 $10.4M
Stifel Financial Corp. 0.01% Reduce -10.9% 216,140 $10.3M
New York State Common Retirement Fund 0.01% Add +62.5% 215,716 $10.3M
ExodusPoint Capital Management, LP 0.11% Reduce -3.1% 209,194 $10.0M
Zimmer Partners, LP 0.18% Reduce -26.0% 200,000 $9.5M
Amova Asset Management Americas, Inc. 0.11% Reduce -9.6% 199,231 $9.5M
Sumitomo Mitsui Trust Group, Inc. 0.01% Reduce -9.6% 199,231 $9.5M
California Public Employees Retirement System 0.01% Reduce -3.7% 196,484 $9.4M
Sicart Associates LLC 3.50% Reduce -1.3% 191,523 $9.1M
D. E. Shaw & Co. 0.01% Add +18.9% 190,781 $9.1M
Altrinsic Global Advisors LLC 0.40% Reduce -3.6% 187,831 $9.0M
BNP Paribas Financial Markets 0.01% Reduce -4.3% 185,944 $8.9M
Jane Street Group, LLC 0.01% Add +51.7% 179,246 $8.5M
Rhumbline Advisers 0.01% Reduce -0.7% 178,089 $8.5M
Marshall Wace, LLP 0.01% Add +1021.5% 173,199 $8.3M
Sector Gamma As 3.03% Reduce -3.1% 170,000 $8.1M
Rafferty Asset Management, LLC 0.03% Reduce -19.0% 168,856 $8.0M
Parkman Healthcare Partners LLC 1.05% Add +14.3% 161,705 $7.7M
Cutter Capital Management, LP 2.33% Reduce -44.6% 160,166 $7.6M
Caption Management, LLC 0.82% New 160,000 $7.6M
HRT Financial LP 0.04% Add +140.1% 159,685 $7.6M
BLB&B Advisors, LLC 0.40% Add +5.2% 153,750 $7.3M
UBS Group AG 0.00% Reduce -11.1% 152,672 $7.3M
State Board of Administration of Florida Retirement System 0.01% Reduce -2.6% 151,055 $7.2M
Tang Capital Management LLC 0.73% No change 150,000 $7.1M
Legal & General Group Plc 0.00% Reduce -1.2% 147,644 $7.0M
Sphera Funds Management LTD. 1.09% New 140,238 $6.7M
Point72 Asset Management 0.02% Reduce -52.1% 137,210 $6.5M
Sonora Investment Management Group, LLC 0.52% No change 150,814 $6.5M
Russell Investments Group, Ltd. 0.01% Reduce -13.5% 132,736 $6.3M
Sei Investments Co. 0.01% Add +65.6% 132,311 $6.3M
Peregrine Capital Management LLC 0.18% Add +11.3% 132,024 $6.3M
Rhenman & Partners Asset Management AB 0.59% New 130,000 $6.2M
Swedbank AB 0.01% Reduce -9.3% 129,373 $6.2M
California State Teachers Retirement System 0.01% Reduce -2.0% 129,216 $6.2M

"% of holder's portfolio" is IONS's weight in each manager's 13F, not the share of Ionis Pharmaceuticals Inc. the manager owns.

Show all 357 holders