Ionis PharmaceuticalsIONS
13F holders, Q2 2024 (June 30)357holders −4
48new positions
53sold out
8famous investors
$47.66avg. 13F price*
At the end of Q2 2024, 357 institutions reported holding Ionis Pharmaceuticals Inc. (IONS) in their 13F filings, down 4 from Q1 2024. 48 opened new positions and 53 sold out. The largest holders were FMR LLC ($1.0B), Vanguard Group Inc. ($659.9M) and T. Rowe Price Investment Management, Inc. ($602.4M). 8 famous investors held it, including Cathie Wood (0.6% of ARK Investment Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Ionis Pharmaceuticals Inc.
- CUSIP
- 462222100
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2024 → Q2 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 48 | $135.7M |
| Exits | 53 | $63.3M |
All 13F filers, Q1 2024 → Q2 2024: 13,822,232 shares bought and 12,772,635 shares sold, net +1,049,597 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 357 holders
| FMR LLC | 0.07% | Add +0.1% | 21,894,806 | $1.0B |
| Vanguard Group Inc. | 0.01% | Add +3.1% | 13,845,712 | $659.9M |
| T. Rowe Price Investment Management, Inc. | 0.38% | Reduce -5.1% | 12,639,684 | $602.4M |
| BlackRock Inc. | 0.01% | Add +5.6% | 10,321,030 | $491.9M |
| Bellevue Group AG | 6.40% | Reduce -0.5% | 8,260,434 | $393.7M |
| Wellington Management Group LLP | 0.06% | Add +15.3% | 6,568,808 | $313.1M |
| State Street Corp. | 0.01% | Add +0.8% | 4,190,505 | $199.7M |
| T. Rowe Price Associates Inc. | 0.02% | Add +11.7% | 3,934,311 | $187.5M |
| Tweedy, Browne Co LLC | 7.57% | No change | 3,454,676 | $164.6M |
| BVF Inc. | 4.26% | Add +31.2% | 3,186,376 | $151.9M |
| Geode Capital Management, LLC | 0.01% | Add +5.1% | 2,484,544 | $118.4M |
| Pictet Asset Management Holding SA | 0.13% | Reduce -35.6% | 2,409,954 | $114.9M |
| Orbimed Advisors LLC | 2.25% | Add +17.9% | 2,372,333 | $113.1M |
| Capital World Investors | 0.02% | Add +168.3% | 2,252,089 | $107.3M |
| Clearbridge Investments, LLC | 0.08% | Reduce -51.6% | 2,160,270 | $103.0M |
| Deep Track Capital, LP | 2.85% | Add +45.6% | 2,000,000 | $95.3M |
| Macquarie Group Ltd. | 0.10% | Reduce -41.5% | 1,873,668 | $89.3M |
| Artisan Partners Limited Partnership | 0.12% | Add +301.0% | 1,671,036 | $79.6M |
| ARK Investment Management | 0.58% | Reduce -2.8% | 1,361,025 | $64.9M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +2.0% | 1,328,106 | $63.3M |
| Two Sigma Advisers, LP | 0.14% | Add +23.8% | 1,287,111 | $61.3M |
| Balyasny Asset Management L.P. | 0.14% | New | 1,077,321 | $51.3M |
| Two Sigma Investments, LP | 0.12% | Reduce -5.1% | 1,028,142 | $49.0M |
| Norges Bank | 0.01% | Reduce -17.6% | 1,019,341 | $48.6M |
| Morgan Stanley | 0.00% | Reduce -13.0% | 1,012,805 | $48.3M |
| Invesco Ltd. | 0.01% | Add +118.8% | 968,917 | $46.2M |
| TD Asset Management Inc | 0.04% | Add +6.1% | 952,762 | $45.4M |
| Candriam S.C.A. | 0.28% | Add +4.0% | 948,266 | $45.2M |
| Adage Capital Partners Gp, L.L.C. | 0.07% | Reduce -20.0% | 800,000 | $38.1M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.10% | Add +0.3% | 780,753 | $37.2M |
| Schonfeld Strategic Advisors LLC | 0.27% | Add +323.5% | 723,618 | $34.5M |
| Northern Trust Corp. | 0.01% | Add +3.7% | 717,975 | $34.2M |
| Royal Bank of Canada | 0.01% | Reduce -7.4% | 678,360 | $32.3M |
| Man Group plc | 0.08% | Add +150.1% | 633,409 | $30.2M |
| Citadel Advisors | 0.03% | Add +703.6% | 627,033 | $29.9M |
| Barclays PLC | 0.01% | Add +6.6% | 615,674 | $29.3M |
| Bank of New York Mellon Corp | 0.01% | Add +2.4% | 597,479 | $28.5M |
| JPMorgan Chase & Co. | 0.00% | Reduce -5.8% | 594,091 | $28.3M |
| Jacobs Levy Equity Management, Inc. | 0.11% | Add +0.2% | 572,870 | $27.3M |
| Bank of America Corp. | 0.00% | Reduce -15.1% | 514,543 | $24.5M |
| Nomura Holdings Inc. | 0.15% | Add +6.5% | 501,188 | $23.9M |
| AXA S.A. | 0.07% | Add +0.0% | 464,963 | $22.2M |
| Eversept Partners, LP | 1.67% | Add +21.4% | 456,881 | $21.8M |
| Pinnacle Associates Ltd. | 0.34% | Reduce -1.4% | 453,379 | $21.6M |
| Squarepoint Ops LLC | 0.08% | Reduce -41.4% | 436,818 | $20.8M |
| Nuveen Asset Management, LLC | 0.01% | Reduce -3.0% | 410,404 | $19.6M |
| Groupama Asset Managment | 0.25% | Add +47.4% | 379,976 | $18.1M |
| Wells Fargo & Company | 0.00% | Reduce -37.3% | 366,561 | $17.5M |
| Hudson Bay Capital Management LP | 0.15% | Add +9.1% | 366,000 | $17.4M |
| Great Point Partners LLC | 3.01% | New | 330,000 | $15.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +63.8% | 328,305 | $15.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +71.9% | 320,290 | $15.3M |
| Logos Global Management LP | 1.65% | New | 300,000 | $14.3M |
| C WorldWide Group Holding A/S | 0.15% | No change | 300,000 | $14.3M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +12.2% | 274,850 | $13.1M |
| Corient Private Wealth LP | 0.02% | Add +0.3% | 268,037 | $12.8M |
| Baillie Gifford & Co. | 0.01% | Reduce -12.0% | 260,254 | $12.4M |
| Swiss National Bank | 0.01% | Add +1.2% | 258,000 | $12.3M |
| Kennedy Capital Management LLC | 0.26% | Add +1.9% | 254,343 | $12.1M |
| Integral Health Asset Management, LLC | 1.19% | New | 250,000 | $11.9M |
| Renaissance Technologies | 0.02% | Add +38.8% | 249,514 | $11.9M |
| Aberdeen Group plc | 0.02% | Add +12.5% | 246,917 | $11.8M |
| Privium Fund Management B.V. | 3.12% | Add +8.9% | 247,267 | $11.2M |
| Tocqueville Asset Management L.P. | 0.18% | Add +41.2% | 225,070 | $10.7M |
| Bank of Montreal | 0.00% | Reduce -1.0% | 220,518 | $10.5M |
| Orion Investment Co | 4.15% | — | 218,570 | $10.4M |
| Stifel Financial Corp. | 0.01% | Reduce -10.9% | 216,140 | $10.3M |
| New York State Common Retirement Fund | 0.01% | Add +62.5% | 215,716 | $10.3M |
| ExodusPoint Capital Management, LP | 0.11% | Reduce -3.1% | 209,194 | $10.0M |
| Zimmer Partners, LP | 0.18% | Reduce -26.0% | 200,000 | $9.5M |
| Amova Asset Management Americas, Inc. | 0.11% | Reduce -9.6% | 199,231 | $9.5M |
| Sumitomo Mitsui Trust Group, Inc. | 0.01% | Reduce -9.6% | 199,231 | $9.5M |
| California Public Employees Retirement System | 0.01% | Reduce -3.7% | 196,484 | $9.4M |
| Sicart Associates LLC | 3.50% | Reduce -1.3% | 191,523 | $9.1M |
| D. E. Shaw & Co. | 0.01% | Add +18.9% | 190,781 | $9.1M |
| Altrinsic Global Advisors LLC | 0.40% | Reduce -3.6% | 187,831 | $9.0M |
| BNP Paribas Financial Markets | 0.01% | Reduce -4.3% | 185,944 | $8.9M |
| Jane Street Group, LLC | 0.01% | Add +51.7% | 179,246 | $8.5M |
| Rhumbline Advisers | 0.01% | Reduce -0.7% | 178,089 | $8.5M |
| Marshall Wace, LLP | 0.01% | Add +1021.5% | 173,199 | $8.3M |
| Sector Gamma As | 3.03% | Reduce -3.1% | 170,000 | $8.1M |
| Rafferty Asset Management, LLC | 0.03% | Reduce -19.0% | 168,856 | $8.0M |
| Parkman Healthcare Partners LLC | 1.05% | Add +14.3% | 161,705 | $7.7M |
| Cutter Capital Management, LP | 2.33% | Reduce -44.6% | 160,166 | $7.6M |
| Caption Management, LLC | 0.82% | New | 160,000 | $7.6M |
| HRT Financial LP | 0.04% | Add +140.1% | 159,685 | $7.6M |
| BLB&B Advisors, LLC | 0.40% | Add +5.2% | 153,750 | $7.3M |
| UBS Group AG | 0.00% | Reduce -11.1% | 152,672 | $7.3M |
| State Board of Administration of Florida Retirement System | 0.01% | Reduce -2.6% | 151,055 | $7.2M |
| Tang Capital Management LLC | 0.73% | No change | 150,000 | $7.1M |
| Legal & General Group Plc | 0.00% | Reduce -1.2% | 147,644 | $7.0M |
| Sphera Funds Management LTD. | 1.09% | New | 140,238 | $6.7M |
| Point72 Asset Management | 0.02% | Reduce -52.1% | 137,210 | $6.5M |
| Sonora Investment Management Group, LLC | 0.52% | No change | 150,814 | $6.5M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -13.5% | 132,736 | $6.3M |
| Sei Investments Co. | 0.01% | Add +65.6% | 132,311 | $6.3M |
| Peregrine Capital Management LLC | 0.18% | Add +11.3% | 132,024 | $6.3M |
| Rhenman & Partners Asset Management AB | 0.59% | New | 130,000 | $6.2M |
| Swedbank AB | 0.01% | Reduce -9.3% | 129,373 | $6.2M |
| California State Teachers Retirement System | 0.01% | Reduce -2.0% | 129,216 | $6.2M |
| Millennium Management | 0.01% | Reduce -78.0% | 128,215 | $6.1M |
| Amundi | 0.00% | Reduce -8.0% | 129,475 | $5.9M |
| Verition Fund Management LLC | 0.05% | Reduce -57.8% | 120,814 | $5.8M |
| Granite Investment Partners, LLC | 0.23% | Reduce -1.8% | 114,090 | $5.4M |
| Nicola Wealth Management LTD. | 0.43% | Add +32.1% | 74,000 | $4.8M |
| Walleye Capital LLC | 0.05% | Add +9.8% | 97,871 | $4.7M |
| Susquehanna International Group, LLP | 0.01% | Reduce -31.1% | 95,858 | $4.6M |
| Voya Investment Management LLC | 0.01% | Add +75.5% | 95,119 | $4.5M |
| Avidity Partners Management LP | 0.19% | Reduce -28.5% | 93,000 | $4.4M |
| DekaBank Deutsche Girozentrale | 0.01% | No change | 93,807 | $4.4M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -18.8% | 88,746 | $4.2M |
| State of Wisconsin Investment Board | 0.01% | Reduce -4.5% | 87,700 | $4.2M |
| DAVENPORT & Co LLC | 0.02% | Reduce -3.9% | 80,678 | $3.8M |
| Two Sigma Securities, LLC | 0.18% | Add +621.1% | 80,198 | $3.8M |
| Envestnet Asset Management Inc. | 0.00% | Reduce -40.4% | 77,415 | $3.7M |
| Citigroup Inc. | 0.00% | Reduce -65.6% | 76,618 | $3.7M |
| Commerce Bank | 0.02% | Reduce -7.4% | 76,342 | $3.6M |
| Algert Global LLC | 0.12% | Add +149.2% | 75,350 | $3.6M |
| Ensign Peak Advisors, Inc | 0.01% | Add +28.0% | 68,270 | $3.3M |
| Simplex Trading, LLC | 0.10% | Add +642.6% | 63,347 | $3.0M |
| Treasurer of the State of North Carolina | 0.01% | Reduce -0.7% | 63,113 | $3.0M |
| Artia Global Partners LP | 0.76% | New | 62,479 | $3.0M |
| Jefferies Financial Group Inc. | 0.06% | Reduce -67.8% | 62,200 | $3.0M |
| GTS Securities LLC | 0.06% | New | 60,930 | $2.9M |
| Skandinaviska Enskilda Banken AB (publ) | 0.01% | No change | 59,626 | $2.8M |
| Liontrust Investment Partners LLP | 0.04% | Reduce -79.3% | 59,644 | $2.8M |
| Janus Henderson Group PLC | 0.00% | Reduce -1.2% | 58,977 | $2.8M |
| Schroder Investment Management Group | 0.00% | Reduce -51.4% | 56,222 | $2.7M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -32.4% | 55,349 | $2.6M |
| Public Employees Retirement System of Ohio | 0.01% | Add +1.5% | 55,296 | $2.6M |
| Teacher Retirement System of Texas | 0.01% | Add +82.9% | 52,552 | $2.5M |
| Bank of Nova Scotia | 0.00% | New | 51,879 | $2.5M |
| LPL Financial LLC | 0.00% | Reduce -35.5% | 51,414 | $2.5M |
| Alliancebernstein L.P. | 0.00% | Reduce -73.2% | 51,268 | $2.4M |
| DRW Securities, LLC | 0.15% | New | 50,956 | $2.4M |
| Erste Asset Management GmbH | 0.03% | No change | 51,300 | $2.4M |
| Van Eck Associates Corp. | 0.00% | Reduce -44.8% | 50,264 | $2.4M |
| Tower Research Capital LLC (TRC) | 0.04% | Add +927.9% | 49,986 | $2.4M |
| Private Advisor Group, LLC | 0.01% | Reduce -3.2% | 46,426 | $2.2M |
| CANADA LIFE ASSURANCE Co | 0.00% | Add +8.8% | 45,548 | $2.2M |
| Susquehanna Fundamental Investments, LLC | 0.05% | No change | 45,574 | $2.2M |
| NEOS Investment Management LLC | 0.09% | Add +20.8% | 45,058 | $2.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | New | 44,256 | $2.1M |
| Susquehanna Portfolio Strategies, LLC | 0.08% | Reduce -67.2% | 43,028 | $2.1M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.06% | Add +0.4% | 42,595 | $2.0M |
| NJ State Employees Deferred Compensation Plan | 0.25% | No change | 42,000 | $2.0M |
| Atle Fund Management AB | 1.18% | Reduce -36.2% | 40,691 | $1.9M |
| Capital Counsel LLC | 0.08% | Reduce -6.3% | 37,080 | $1.8M |
| Arizona State Retirement System | 0.01% | Add +3.5% | 36,722 | $1.8M |
| Guggenheim Capital LLC | 0.01% | Reduce -1.3% | 35,389 | $1.7M |
| Cubist Systematic Strategies, LLC | 0.03% | Reduce -87.3% | 35,311 | $1.7M |
| Grandfield & Dodd, LLC | 0.10% | Add +0.8% | 34,053 | $1.6M |
| Handelsbanken Fonder AB | 0.01% | No change | 33,911 | $1.6M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +10.7% | 31,155 | $1.5M |
| Trexquant Investment LP | 0.02% | Reduce -64.8% | 30,086 | $1.4M |
| Profund Advisors LLC | 0.05% | Reduce -5.0% | 29,983 | $1.4M |
| Creative Planning | 0.00% | Reduce -0.5% | 26,860 | $1.3M |
| Blair William & Co. | 0.00% | Reduce -9.3% | 25,262 | $1.2M |
| Teza Capital Management LLC | 0.15% | Reduce -16.0% | 25,159 | $1.2M |
| Assenagon Asset Management S.A. | 0.00% | Reduce -91.1% | 24,226 | $1.2M |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 24,083 | $1.1M |
| Raymond James & Associates | 0.00% | Reduce -79.1% | 23,573 | $1.1M |
| Natixis Advisors, LLC | 0.00% | Add +1.6% | 23,404 | $1.1M |
| DCF Advisers, LLC | 0.58% | New | 23,000 | $1.1M |
| Pathstone Holdings, LLC | 0.00% | Add +6.8% | 22,705 | $1.1M |
| Commonwealth Equity Services, LLC | 0.00% | Add +3.2% | 22,669 | $1.1M |
| Mariner, LLC | 0.00% | Add +5.2% | 21,854 | $1.0M |
| Brevan Howard Capital Management LP | 0.07% | Add +343.7% | 21,847 | $1.0M |
| Comerica Bank | 0.00% | Reduce -45.8% | 21,424 | $1.0M |
| Wolverine Trading, LLC | 0.02% | Add +77.0% | 21,328 | $1.0M |
| Nicollet Investment Management, Inc. | 0.36% | Reduce -2.0% | 20,108 | $958K |
| Tidal Investments LLC | 0.01% | Reduce -7.1% | 18,950 | $903K |
| Xponance LLC | 0.01% | Add +11.8% | 18,115 | $863K |
| Janney Montgomery Scott LLC | 0.00% | Reduce -34.8% | 17,534 | $836K |
| J. Goldman & Co LP | 0.03% | Reduce -92.4% | 17,502 | $834K |
| Principal Financial Group Inc. | 0.00% | Reduce -41.5% | 17,458 | $832K |
| Victory Capital Management Inc. | 0.00% | Reduce -1.7% | 17,330 | $826K |
| Inceptionr LLC | 0.23% | New | 17,289 | $824K |
| China Universal Asset Management Co., Ltd. | 0.12% | Reduce -38.8% | 17,150 | $817K |
| NBT Bank, N.A. | 0.06% | No change | 17,050 | $813K |
| Bleakley Financial Group, LLC | 0.02% | Add +0.7% | 16,340 | $779K |
| Simplicity Wealth,LLC | 0.02% | Add +0.7% | 16,340 | $779K |
| Engineers Gate Manager LP | 0.02% | Reduce -57.7% | 16,320 | $778K |
| Eisler Capital (US) LLC | 0.15% | New | 16,270 | $775K |
| First Trust Advisors LP | 0.00% | Reduce -90.8% | 16,194 | $772K |
| Prudential Financial Inc. | 0.00% | New | 15,717 | $749K |
| Public Employees Retirement Association of Colorado | 0.00% | Reduce -5.9% | 15,589 | $743K |
| Raymond James Financial Services Advisors, Inc. | 0.00% | Add +13.5% | 15,335 | $731K |
| PEAK6 Investments LLC | 0.03% | Add +36.4% | 15,001 | $715K |
| Osaic Holdings, Inc. | 0.00% | Add +0.5% | 14,692 | $700K |
| Tanaka Capital Management Inc. | 1.64% | Reduce -0.7% | 14,512 | $692K |
| Sanctuary Advisors, LLC | 0.01% | — | 16,441 | $684K |
| Neuberger Berman Group LLC | 0.00% | Add +0.6% | 14,312 | $682K |
| Chartwell Investment Partners, LLC | 0.02% | Add +17.0% | 13,759 | $656K |
| North Star Asset Management Inc. | 0.03% | No change | 13,640 | $650K |
| American Century Companies Inc. | 0.00% | Add +0.5% | 13,441 | $641K |
| PDT Partners, LLC | 0.06% | New | 13,430 | $640K |
| Westmount Partners, LLC | 0.21% | Reduce -3.0% | 13,462 | $634K |
| Tudor Investment Corporation | 0.01% | New | 13,098 | $624K |
| Martingale Asset Management L P | 0.01% | Reduce -3.8% | 12,805 | $610K |
| Stratos Wealth Partners, LTD. | 0.01% | New | 12,791 | $610K |
| Horizon Kinetics Asset Management LLC | 0.01% | No change | 12,476 | $595K |
| Parallax Volatility Advisers, L.P. | 0.02% | New | 12,310 | $587K |
| SpiderRock Advisors, LLC | 0.02% | New | 12,026 | $573K |
| Plancorp, LLC | 0.02% | Add +1.2% | 11,286 | $538K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Add +0.6% | 11,213 | $534K |
| US Bancorp \de | 0.00% | Reduce -7.3% | 11,050 | $527K |
| Brown Advisory Inc. | 0.00% | Reduce -1.4% | 10,966 | $523K |
| Maryland State Retirement & Pension System | 0.01% | No change | 10,950 | $522K |
| Lisanti Capital Growth, LLC | 0.12% | Reduce -61.0% | 10,845 | $517K |
| Montanova Capital, LLC | 0.02% | No change | 10,800 | $515K |
| Twin Tree Management, LP | 0.01% | Add +37.3% | 10,381 | $495K |
| E Fund Management Co., Ltd. | 0.03% | Add +4.4% | 10,255 | $489K |
| Midwest Professional Planners, LTD. | 0.16% | Add +4.4% | 10,140 | $483K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +7.9% | 10,048 | $479K |
| Franklin Resources Inc. | 0.00% | Add +2.2% | 10,022 | $478K |
| Cypress Capital, LLC | 0.13% | No change | 10,000 | $477K |
| International Assets Investment Management, LLC | 0.04% | Add +27.6% | 9,707 | $463K |
| Sectoral Asset Management Inc. | 0.19% | Reduce -4.4% | 9,660 | $460K |
| Amalgamated Bank | 0.00% | Add +4.9% | 9,657 | $460K |
| Lazard Asset Management LLC | 0.00% | Add +21.1% | 9,515 | $452K |
| Fifth Third Bancorp | 0.00% | Reduce -1.8% | 9,462 | $451K |
| Annis Gardner Whiting Capital Advisors, LLC | 0.13% | New | 9,396 | $448K |
| PNC Financial Services Group, Inc. | 0.00% | Add +6.2% | 9,361 | $446K |
| Deutsche Bank AG | 0.00% | Add +5.9% | 9,096 | $434K |
| ProShare Advisors LLC | 0.00% | Reduce -11.8% | 9,011 | $429K |
| MetLife Investment Management, LLC | 0.00% | Add +12.9% | 8,849 | $422K |
| M&T Bank Corp | 0.00% | Add +50.9% | 8,826 | $421K |
| Ameriprise Financial Inc. | 0.00% | Reduce -43.9% | 8,792 | $419K |
| Clearstead Advisors, LLC | 0.01% | Add +1573.7% | 8,285 | $395K |
| Gsa Capital Partners LLP | 0.03% | Reduce -1.1% | 8,231 | $392K |
| Virtus Advisers, LLC | 0.19% | Add +4.7% | 8,009 | $382K |
| Truist Financial Corp. | 0.00% | Reduce -15.8% | 8,003 | $381K |
| Vontobel Holding Ltd. | 0.00% | Add +6.5% | 7,985 | $381K |
| Utah Retirement Systems | 0.00% | No change | 7,900 | $377K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Add +3.5% | 7,624 | $363K |
| Castle Rock Wealth Management, LLC | 0.08% | No change | 6,972 | $328K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | — | 6,357 | $300K |
| Gotham Asset Management | 0.00% | Reduce -7.7% | 6,262 | $298K |
| Pearl River Capital, LLC | 0.05% | Reduce -76.2% | 6,187 | $295K |
| Jump Financial, LLC | 0.01% | Reduce -60.6% | 6,184 | $295K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | Add +58.1% | 6,074 | $289K |
| Oppenheimer Asset Management Inc. | 0.00% | Reduce -41.2% | 5,777 | $275K |
| HighTower Advisors, LLC | 0.00% | Add +10.8% | 5,634 | $271K |
| Readystate Asset Management LP | 0.02% | New | 5,600 | $267K |
| Perkins Capital Management Inc. | 0.25% | No change | 5,550 | $265K |
| Bridgefront Capital, LLC | 0.11% | New | 5,559 | $265K |
| Fox Run Management, L.L.C. | 0.05% | New | 5,421 | $258K |
| HSBC Holdings PLC | 0.00% | New | 5,326 | $252K |
| Buckingham Strategic Wealth, LLC | 0.00% | No change | 5,251 | $250K |
| Stephens Inc. | 0.00% | Reduce -34.6% | 5,138 | $245K |
| Advisors Asset Management, Inc. | 0.00% | Add +59.7% | 5,074 | $242K |
| Beaird Harris Wealth Management, LLC | 0.02% | No change | 5,000 | $238K |
| Kestra Advisory Services, LLC | 0.00% | Reduce -1.1% | 5,491 | $236K |
| Farallon Capital Management, L.L.C. | 0.00% | Reduce -99.3% | 4,800 | $229K |
| Point72 (DIFC) Ltd | 0.02% | Reduce -83.5% | 4,694 | $224K |
| Mitchell & Pahl Private Wealth, LLC | 0.11% | New | 4,540 | $216K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | New | 4,508 | $215K |
| Prospera Financial Services Inc | 0.01% | Reduce -3.6% | 4,451 | $212K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -71.1% | 4,358 | $206K |
| Checchi Capital Advisers, LLC | 0.02% | New | 4,234 | $202K |
| CI Investments Inc. | 0.00% | Reduce -7.9% | 3,652 | $174K |
| Jones Financial Companies LLLP | 0.00% | New | 3,401 | $162K |
| KBC Group NV | 0.00% | Add +7.8% | 3,389 | $162K |
| Corebridge Financial, Inc. | 0.00% | — | 2,761 | $132K |
| Redwood Wealth Management Group, LLC | 0.09% | New | 2,408 | $115K |
| Cwm, LLC | 0.00% | Reduce -0.5% | 2,217 | $106K |
| NewEdge Advisors, LLC | 0.00% | Add +6.2% | 2,150 | $102K |
| CIBC Private Wealth Group LLC | 0.00% | Reduce -2.0% | 2,125 | $100K |
| Twin Lakes Capital Management, LLC | 0.05% | No change | 1,500 | $71K |
| ADAR1 Capital Management, LLC | 0.01% | Reduce -48.3% | 1,500 | $71K |
| Horizon Investments, LLC | 0.00% | Reduce -36.3% | 1,494 | $71K |
| AlphaQuest LLC | 0.01% | Reduce -40.2% | 1,373 | $65K |
| IFP Advisors, Inc | 0.00% | No change | 1,070 | $51K |
| Sunbelt Securities, Inc. | 0.00% | No change | 1,014 | $48K |
| Pacer Advisors, Inc. | 0.00% | Reduce -1.1% | 960 | $46K |
| Harbour Investments, Inc. | 0.00% | No change | 900 | $43K |
| Quadrant Capital Group LLC | 0.00% | Add +49.8% | 860 | $41K |
| Mather Group, Llc. | 0.00% | Add +35.8% | 911 | $39K |
| Allworth Financial LP | 0.00% | Add +1.6% | 809 | $39K |
| Itau Unibanco Holding S.A. | 0.00% | New | 767 | $37K |
| Manchester Capital Management LLC | 0.00% | Add +13800.0% | 695 | $33K |
| Parallel Advisors, LLC | 0.00% | Add +10.5% | 632 | $30K |
| Steward Partners Investment Advisory, LLC | 0.00% | Reduce -13.0% | 629 | $30K |
| nVerses Capital, LLC | 0.02% | New | 600 | $29K |
| Archer Investment Corp | 0.01% | Reduce -29.4% | 600 | $29K |
| Laurel Wealth Advisors LLC | 0.01% | No change | 600 | $29K |
| AlphaMark Advisors, LLC | 0.01% | Add +42.5% | 570 | $27K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -1.1% | 563 | $27K |
| Daiwa Securities Group Inc. | 0.00% | No change | 541 | $26K |
| Pingora Partners LLC | 0.02% | No change | 500 | $24K |
| Riverview Trust Co | 0.02% | No change | 476 | $23K |
| Global Trust Asset Management, LLC | 0.01% | No change | 474 | $23K |
| Danske Bank A/S | 0.00% | New | 400 | $19K |
| Banque Cantonale Vaudoise | 0.00% | No change | 400 | $19K |
| ORG Partners LLC | 0.00% | New | 400 | $19K |
| Lindbrook Capital, LLC | 0.00% | Add +23.9% | 389 | $19K |
| Institutional & Family Asset Management, LLC | 0.00% | Reduce -47.8% | 361 | $17K |
| GAMMA Investing LLC | 0.00% | Reduce -41.0% | 361 | $17K |
| Signaturefd, LLC | 0.00% | Reduce -4.2% | 340 | $16K |
| Huntington National Bank | 0.00% | Reduce -11.3% | 322 | $15K |
| Storebrand Asset Management As | 0.00% | No change | 271 | $13K |
| Global X Japan Co., Ltd. | 0.00% | Reduce -60.8% | 262 | $12K |
| Covestor Ltd | 0.01% | Add +0.4% | 243 | $12K |
| Riggs Asset Managment Co. Inc. | 0.00% | Reduce -11.3% | 250 | $12K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +0.4% | 238 | $12K |
| Whittier Trust Co. of Nevada Inc. | 0.00% | Reduce -36.1% | 218 | $10K |
| Whittier Trust Co. | 0.00% | Reduce -7.4% | 214 | $10K |
| Parkside Financial Bank & Trust | 0.00% | Add +221.0% | 199 | $9K |
| AllSquare Wealth Management LLC | 0.01% | No change | 198 | $9K |
| LRI Investments, LLC | 0.00% | New | 187 | $9K |
| Allspring Global Investments Holdings, LLC | 0.00% | Add +937.5% | 166 | $8K |
| Natixis | 0.00% | Reduce -91.7% | 163 | $8K |
| Ashton Thomas Private Wealth, LLC | 0.00% | New | 150 | $7K |
| Pacifica Partners Inc. | 0.00% | No change | 150 | $7K |
| Dunhill Financial, LLC | 0.00% | New | 130 | $6K |
| Unique Wealth Strategies, LLC | 0.00% | New | 140 | $6K |
| Spire Wealth Management | 0.00% | No change | 125 | $6K |
| GPS Wealth Strategies Group, LLC | 0.00% | Reduce -35.3% | 119 | $6K |
| Washington Trust Advisors, Inc. | 0.00% | Reduce -57.0% | 111 | $5K |
| Arax Advisory Partners | 0.00% | Add +316.0% | 104 | $5K |
| Sachetta, LLC | 0.00% | Reduce -14.8% | 98 | $5K |
| Creekmur Asset Management LLC | 0.00% | No change | 100 | $5K |
| Global Retirement Partners, LLC | 0.00% | Add +4.3% | 98 | $5K |
| Blue Trust, Inc. | 0.00% | New | 107 | $5K |
| Family Firm, Inc. | 0.00% | New | 91 | $4K |
| Bogart Wealth, LLC | 0.00% | No change | 85 | $4K |
| Dynamic Wealth Strategies, LLC | 0.00% | No change | 80 | $4K |
| Private Trust Co. NA | 0.00% | Reduce -78.0% | 83 | $4K |
| Orion Capital Management LLC | 0.00% | No change | 80 | $4K |
| National Bank of Canada | 0.00% | No change | 80 | $4K |
| Semmax Financial Advisors Inc. | 0.00% | No change | 79 | $4K |
| Quent Capital, LLC | 0.00% | Add +34.5% | 74 | $4K |
| SYSTM Wealth Solutions LLC | 0.00% | Reduce -64.2% | 73 | $3K |
| Raleigh Capital Management Inc. | 0.00% | No change | 72 | $3K |
| Bell Investment Advisors, Inc | 0.00% | No change | 71 | $3K |
| Smartleaf Asset Management LLC | 0.00% | Add +126.9% | 59 | $3K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Reduce -13.4% | 58 | $3K |
| Blume Capital Management, Inc. | 0.00% | No change | 55 | $3K |
| Versant Capital Management, Inc | 0.00% | Reduce -6.8% | 55 | $3K |
| Innealta Capital, LLC | 0.00% | New | 47 | $2K |
| Healthcare of Ontario Pension Plan Trust Fund | 0.00% | New | 46 | $2K |
| Abich Financial Wealth Management LLC | 0.00% | Add +1025.0% | 45 | $2K |
| Great Lakes Retirement, Inc. | 0.00% | New | 43 | $2K |
| Bessemer Group Inc. | 0.00% | No change | 52 | $2K |
| Sandy Spring Bank | 0.00% | No change | 34 | $2K |
| Kelly Financial Services LLC | 0.00% | No change | 30 | $1K |
| Raffa Wealth Management, LLC | 0.00% | No change | 28 | $1K |
| Concourse Financial Group Securities, Inc. | 0.00% | Add +36.8% | 26 | $1K |
| TFC Financial Management, Inc. | 0.00% | New | 21 | $1K |
| Thurston, Springer, Miller, Herd & Titak, Inc. | 0.00% | New | 20 | $953 |
| Front Row Advisors LLC | 0.00% | No change | 20 | $953 |
| Rosenberg Matthew Hamilton | 0.00% | No change | 20 | $942 |
| Key Financial Inc | 0.00% | No change | 19 | $906 |
| Larson Financial Group LLC | 0.00% | New | 18 | $858 |
| Principal Securities, Inc. | 0.00% | New | 13 | $620 |
| Private Wealth Management Group, LLC | 0.00% | No change | 10 | $477 |
"% of holder's portfolio" is IONS's weight in each manager's 13F, not the share of Ionis Pharmaceuticals Inc. the manager owns.