Ionis PharmaceuticalsIONS
13F holders, Q3 2024 (September 30)354holders −3
49new positions
49sold out
7famous investors
$40.09avg. 13F price*
At the end of Q3 2024, 354 institutions reported holding Ionis Pharmaceuticals Inc. (IONS) in their 13F filings, down 3 from Q2 2024. 49 opened new positions and 49 sold out. The largest holders were FMR LLC ($900.5M), Vanguard Group Inc. ($603.1M) and T. Rowe Price Investment Management, Inc. ($567.6M). 7 famous investors held it, including Cathie Wood (0.5% of ARK Investment Management's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Ionis Pharmaceuticals Inc.
- CUSIP
- 462222100
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2024 → Q3 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 49 | $101.0M |
| Exits | 49 | $128.4M |
All 13F filers, Q2 2024 → Q3 2024: 23,000,580 shares bought and 9,745,087 shares sold, net +13,255,493 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 354 holders
| FMR LLC | 0.05% | Add +2.7% | 22,479,529 | $900.5M |
| Vanguard Group Inc. | 0.01% | Add +8.7% | 15,055,758 | $603.1M |
| T. Rowe Price Investment Management, Inc. | 0.34% | Add +12.1% | 14,168,116 | $567.6M |
| BlackRock, Inc. | 0.01% | — | 10,813,023 | $433.2M |
| Wellington Management Group LLP | 0.06% | Add +33.0% | 8,735,787 | $350.0M |
| Bellevue Group AG | 5.11% | Reduce -4.7% | 7,874,400 | $315.4M |
| Capital World Investors | 0.05% | Add +247.6% | 7,828,372 | $313.6M |
| State Street Corp. | 0.01% | Add +15.7% | 4,850,137 | $194.3M |
| T. Rowe Price Associates Inc. | 0.02% | Add +7.0% | 4,210,172 | $168.7M |
| Tweedy, Browne Co LLC | 6.60% | No change | 3,454,676 | $138.4M |
| Geode Capital Management, LLC | 0.01% | Add +7.4% | 2,668,358 | $106.9M |
| Orbimed Advisors LLC | 1.70% | Reduce -2.0% | 2,324,447 | $93.1M |
| Artisan Partners Limited Partnership | 0.13% | Add +34.1% | 2,240,455 | $89.8M |
| Deep Track Capital, LP | 2.81% | Add +10.0% | 2,200,000 | $88.1M |
| Norges Bank | 0.01% | Add +98.9% | 2,027,161 | $81.2M |
| Marshall Wace, LLP | 0.10% | Add +1008.8% | 1,920,464 | $76.9M |
| Macquarie Group Ltd. | 0.08% | Reduce -0.2% | 1,869,806 | $74.9M |
| Clearbridge Investments, LLC | 0.05% | Reduce -21.2% | 1,702,393 | $68.2M |
| BVF Inc. | 1.70% | Reduce -54.4% | 1,451,879 | $58.2M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +8.7% | 1,443,020 | $57.8M |
| ARK Investment Management | 0.51% | Add +1.7% | 1,384,269 | $55.5M |
| Two Sigma Advisers, LP | 0.13% | Add +3.5% | 1,332,411 | $53.4M |
| Pictet Asset Management Holding SA | 0.06% | Reduce -45.9% | 1,303,501 | $52.7M |
| Morgan Stanley | 0.00% | Add +29.4% | 1,310,451 | $52.5M |
| TD Asset Management Inc | 0.04% | Add +14.7% | 1,092,990 | $44.6M |
| Candriam S.C.A. | 0.22% | No change | 948,266 | $38.0M |
| Two Sigma Investments, LP | 0.09% | Reduce -10.6% | 919,077 | $36.8M |
| Invesco Ltd. | 0.01% | Reduce -16.4% | 810,301 | $32.5M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.08% | Reduce -0.1% | 779,721 | $31.2M |
| Hudson Bay Capital Management LP | 0.25% | Add +109.5% | 766,900 | $30.7M |
| Logos Global Management LP | 3.37% | Add +150.0% | 750,000 | $30.0M |
| Northern Trust Corp. | 0.00% | Add +3.5% | 742,904 | $29.8M |
| Royal Bank of Canada | 0.01% | Reduce -1.2% | 670,149 | $26.8M |
| Jacobs Levy Equity Management, Inc. | 0.10% | Add +13.6% | 650,779 | $26.1M |
| Barclays PLC | 0.01% | Add +3.5% | 637,032 | $25.5M |
| Bank of New York Mellon Corp | 0.00% | Add +2.3% | 610,893 | $24.5M |
| J. Goldman & Co LP | 1.06% | Add +3382.0% | 609,416 | $24.4M |
| Man Group plc | 0.07% | Reduce -5.9% | 596,263 | $23.9M |
| Pinnacle Associates Ltd. | 0.39% | Add +1.2% | 458,979 | $23.2M |
| JPMorgan Chase & Co. | 0.00% | Reduce -4.2% | 568,906 | $22.8M |
| Bank of America Corp. | 0.00% | Add +10.5% | 568,660 | $22.8M |
| AXA S.A. | 0.07% | Add +20.7% | 561,243 | $22.5M |
| EcoR1 Capital, LLC | 0.69% | New | 500,000 | $20.0M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | Reduce -37.5% | 500,000 | $20.0M |
| Eversept Partners, LP | 1.45% | Add +3.2% | 471,355 | $18.9M |
| Nomura Holdings Inc. | 0.14% | Reduce -9.6% | 453,069 | $18.1M |
| Millennium Management | 0.02% | Add +235.9% | 430,723 | $17.3M |
| Tocqueville Asset Management L.P. | 0.26% | Add +80.8% | 406,870 | $16.3M |
| First Trust Advisors LP | 0.02% | Add +2384.3% | 402,300 | $16.1M |
| Citadel Advisors | 0.02% | Reduce -36.0% | 401,151 | $16.1M |
| Ghisallo Capital Management LLC | 0.87% | New | 400,000 | $16.0M |
| Ameriprise Financial Inc. | 0.00% | Add +4425.7% | 397,898 | $15.9M |
| Voloridge Investment Management, LLC | 0.06% | New | 380,641 | $15.2M |
| Schonfeld Strategic Advisors LLC | 0.12% | Reduce -49.9% | 362,888 | $14.5M |
| Wells Fargo & Company | 0.00% | Reduce -6.7% | 342,154 | $13.7M |
| Groupama Asset Managment | 0.35% | Add +9.5% | 416,060 | $13.4M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +12.4% | 308,947 | $12.4M |
| Nuveen Asset Management, LLC | 0.00% | Reduce -25.7% | 304,779 | $12.2M |
| Aberdeen Group plc | 0.02% | Add +22.8% | 303,274 | $12.1M |
| C WorldWide Group Holding A/S | 0.12% | No change | 300,000 | $12.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -10.8% | 285,697 | $11.4M |
| Swiss National Bank | 0.01% | Reduce -0.5% | 256,600 | $10.3M |
| Great Point Partners LLC | 3.08% | Reduce -22.7% | 255,000 | $10.2M |
| Privium Fund Management B.V. | 2.50% | Add +1.4% | 250,744 | $10.0M |
| Siren, L.L.C. | 0.50% | — | 250,000 | $10.0M |
| Corient Private Wealth LP | 0.01% | Reduce -11.6% | 237,076 | $9.5M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -28.2% | 235,710 | $9.4M |
| Twinbeech Capital LP | 0.18% | New | 235,477 | $9.4M |
| Driehaus Capital Management LLC | 0.08% | New | 229,969 | $9.2M |
| Baker Bros. Advisors LP | 0.09% | New | 223,470 | $9.0M |
| Orion Investment Co | 3.40% | Reduce -0.0% | 218,525 | $8.8M |
| Bank of Montreal | 0.00% | Reduce -3.0% | 213,883 | $8.7M |
| California Public Employees Retirement System | 0.01% | Add +7.8% | 211,756 | $8.5M |
| Sector Gamma As | 2.56% | Add +24.0% | 210,842 | $8.4M |
| Rafferty Asset Management, LLC | 0.03% | Add +17.7% | 198,759 | $8.0M |
| New York State Common Retirement Fund | 0.01% | Reduce -7.9% | 198,759 | $8.0M |
| Rhumbline Advisers | 0.01% | Add +10.6% | 196,942 | $7.9M |
| Amova Asset Management Americas, Inc. | 0.09% | Reduce -1.6% | 196,114 | $7.9M |
| Sumitomo Mitsui Trust Group, Inc. | 0.01% | Reduce -1.6% | 196,114 | $7.9M |
| Rhenman & Partners Asset Management AB | 0.63% | Add +50.0% | 195,000 | $7.8M |
| Sicart Associates LLC | 2.69% | No change | 191,523 | $7.7M |
| Renaissance Technologies | 0.01% | Reduce -23.6% | 190,514 | $7.6M |
| Sei Investments Co. | 0.01% | Add +43.5% | 189,837 | $7.6M |
| Altrinsic Global Advisors LLC | 0.31% | Reduce -2.7% | 182,734 | $7.3M |
| Stifel Financial Corp. | 0.01% | Reduce -15.6% | 182,505 | $7.3M |
| Jane Street Group, LLC | 0.01% | Reduce -1.5% | 176,560 | $7.1M |
| BNP Paribas Financial Markets | 0.01% | Reduce -5.7% | 175,328 | $7.0M |
| Alyeska Investment Group, L.P. | 0.03% | New | 168,951 | $6.8M |
| UBS Group AG | 0.00% | Add +10.0% | 167,880 | $6.7M |
| Kennedy Capital Management LLC | 0.14% | Reduce -36.3% | 162,076 | $6.5M |
| Legal & General Group Plc | 0.00% | Add +6.5% | 157,287 | $6.3M |
| Sonora Investment Management Group, LLC | 0.46% | Add +1.6% | 153,175 | $6.1M |
| BLB&B Advisors, LLC | 0.31% | Reduce -1.0% | 152,250 | $6.1M |
| State Board of Administration of Florida Retirement System | 0.01% | No change | 151,055 | $6.1M |
| Tang Capital Management LLC | 0.43% | No change | 150,000 | $6.0M |
| D. E. Shaw & Co. | 0.01% | Reduce -23.9% | 145,091 | $5.8M |
| Peregrine Capital Management LLC | 0.16% | Reduce -0.3% | 131,630 | $5.3M |
| Trexquant Investment LP | 0.07% | Add +334.9% | 130,858 | $5.2M |
| Swedbank AB | 0.01% | No change | 129,373 | $5.2M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -3.2% | 128,469 | $5.1M |
"% of holder's portfolio" is IONS's weight in each manager's 13F, not the share of Ionis Pharmaceuticals Inc. the manager owns.