Rhythm PharmaceuticalsRYTM
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 281 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, up 17 from Q3 2025. 48 opened new positions and 39 sold out. The largest holders were Ra Capital Management, L.P. ($713.6M), BlackRock, Inc. ($674.1M) and Vanguard Group Inc. ($664.8M). 7 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Rhythm Pharmaceuticals Inc.
- CUSIP
- 76243J105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 48 | $127.7M |
| Exits | 39 | $195.0M |
All 13F filers, Q3 2025 → Q4 2025: 7,739,927 shares bought and 5,908,810 shares sold, net +1,831,117 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 281 holders
| Ra Capital Management, L.P. | 7.32% | Add +17.4% | 6,666,837 | $713.6M |
| BlackRock, Inc. | 0.01% | Reduce -0.1% | 6,297,334 | $674.1M |
| Vanguard Group Inc. | 0.01% | Add +24.3% | 6,210,916 | $664.8M |
| Baker Bros. Advisors LP | 3.53% | No change | 5,604,483 | $599.9M |
| Primecap Management Co. | 0.28% | Reduce -18.4% | 3,478,669 | $372.4M |
| NEA Management Company, LLC | 15.88% | No change | 2,909,956 | $311.5M |
| Perceptive Advisors LLC | 5.01% | Add +4.4% | 2,546,391 | $272.6M |
| State Street Corp. | 0.01% | Add +8.4% | 2,198,615 | $235.3M |
| Goldman Sachs Group Inc. | 0.03% | Reduce -3.3% | 1,830,866 | $196.0M |
| FMR LLC | 0.01% | Reduce -20.5% | 1,706,317 | $182.6M |
| Federated Hermes, Inc. | 0.29% | Reduce -6.0% | 1,623,841 | $173.8M |
| T. Rowe Price Associates Inc. | 0.02% | Add +11.5% | 1,560,847 | $167.1M |
| JPMorgan Chase & Co. | 0.01% | Add +19.9% | 1,423,989 | $152.4M |
| Geode Capital Management, LLC | 0.01% | Add +0.9% | 1,375,729 | $147.3M |
| Driehaus Capital Management LLC | 0.93% | Reduce -7.1% | 1,285,222 | $137.6M |
| Westfield Capital Management Co. LP | 0.56% | Add +18.5% | 1,267,158 | $135.6M |
| Polar Capital Holdings Plc | 0.58% | Reduce -4.8% | 1,185,392 | $126.9M |
| Janus Henderson Group PLC | 0.05% | Reduce -3.0% | 1,126,125 | $120.6M |
| Checkpoint Capital L.P. | 33.65% | Add +29.9% | 992,200 | $106.2M |
| Capital Research Global Investors | 0.02% | Add +64.7% | 985,086 | $105.4M |
| Alliancebernstein L.P. | 0.03% | Reduce -5.0% | 930,233 | $99.6M |
| Jennison Associates LLC | 0.06% | Add +123.2% | 918,567 | $98.3M |
| Franklin Resources Inc. | 0.02% | Add +22.5% | 695,735 | $74.5M |
| Rock Springs Capital Management LP | 3.83% | Reduce -3.1% | 695,010 | $74.4M |
| Woodline Partners LP | 0.29% | Add +18.7% | 688,779 | $73.7M |
| Morgan Stanley | 0.00% | Add +40.0% | 651,402 | $69.7M |
| Adage Capital Partners Gp, L.L.C. | 0.10% | Add +14.3% | 621,585 | $66.5M |
| Lord, Abbett & Co. LLC | 0.21% | Add +7.6% | 619,542 | $66.3M |
| Pictet Asset Management Holding SA | 0.06% | Reduce -10.0% | 614,663 | $66.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +25.5% | 549,020 | $58.8M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +0.9% | 532,447 | $57.0M |
| Clearbridge Investments, LLC | 0.04% | Add +4.4% | 506,109 | $54.2M |
| Loomis Sayles & Co. L P | 0.07% | Reduce -4.5% | 503,901 | $53.9M |
| Siren, L.L.C. | 1.60% | No change | 499,975 | $53.5M |
| Northern Trust Corp. | 0.01% | Reduce -4.4% | 488,216 | $52.3M |
| Integral Health Asset Management, LLC | 2.58% | Add +115.9% | 475,000 | $50.8M |
| Point72 Asset Management | 0.08% | New | 429,420 | $46.0M |
| UBS Group AG | 0.01% | Add +1.6% | 427,236 | $45.7M |
| Renaissance Technologies | 0.06% | Reduce -37.6% | 341,193 | $36.5M |
| Opaleye Management Inc. | 4.66% | Reduce -28.5% | 330,000 | $35.3M |
| Qube Research & Technologies Ltd | 0.05% | Add +30.2% | 310,919 | $33.3M |
| Bank of New York Mellon Corp | 0.01% | Add +65.1% | 301,080 | $32.2M |
| First Light Asset Management, LLC | 2.42% | Add +63.9% | 295,844 | $31.7M |
| Invesco Ltd. | 0.00% | Add +102.8% | 291,150 | $31.2M |
| Candriam S.C.A. | 0.15% | Add +29.8% | 287,907 | $30.8M |
| Sofinnova Investments, Inc. | 1.25% | Add +9.9% | 271,394 | $29.1M |
| Artisan Partners Limited Partnership | 0.04% | Add +11.3% | 263,591 | $28.2M |
| Ameriprise Financial Inc. | 0.01% | Add +89.3% | 261,160 | $28.0M |
| Wellington Management Group LLP | 0.00% | Add +922.0% | 250,156 | $26.8M |
| Voya Investment Management LLC | 0.03% | Add +12.8% | 249,874 | $26.7M |
| Orbimed Advisors LLC | 0.53% | Add +11.5% | 239,800 | $25.7M |
| Hood River Capital Management LLC | 0.28% | Add +0.5% | 237,043 | $25.4M |
| Bank of America Corp. | 0.00% | Reduce -3.7% | 224,484 | $24.0M |
| Logos Global Management LP | 1.36% | Reduce -5.0% | 190,000 | $20.3M |
| Millennium Management | 0.01% | Add +40.2% | 186,709 | $20.0M |
| BNP Paribas Financial Markets | 0.01% | Reduce -26.4% | 164,563 | $17.6M |
| Citadel Advisors | 0.01% | Add +15.6% | 153,322 | $16.4M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.04% | Add +23.2% | 149,373 | $16.0M |
| First Turn Management, LLC | 1.79% | New | 146,303 | $15.7M |
| M&G PLC | 0.08% | New | 137,074 | $14.7M |
| Silverarc Capital Management, LLC | 2.11% | Reduce -63.3% | 135,950 | $14.6M |
| Russell Investments Group, Ltd. | 0.02% | Reduce -14.9% | 134,180 | $14.4M |
| Barclays PLC | 0.01% | Reduce -7.7% | 131,436 | $14.1M |
| Deutsche Bank AG | 0.00% | Add +10.6% | 129,123 | $13.8M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | Add +21.9% | 123,537 | $13.2M |
| Nuveen, LLC | 0.00% | Reduce -1.7% | 115,934 | $12.4M |
| Capital World Investors | 0.00% | New | 115,693 | $12.4M |
| Swiss National Bank | 0.01% | Add +8.8% | 111,300 | $11.9M |
| New York State Common Retirement Fund | 0.01% | Add +24.7% | 93,677 | $10.0M |
| First Trust Advisors LP | 0.01% | Add +9.4% | 88,505 | $9.5M |
| Algert Global LLC | 0.15% | Reduce -37.1% | 88,250 | $9.4M |
| Axiom Investors LLC | 0.08% | Add +0.6% | 83,554 | $8.9M |
| Zweig-DiMenna Associates LLC | 0.62% | New | 81,600 | $8.7M |
| SummitTX Capital, L.P. | 0.26% | Add +580.2% | 80,729 | $8.6M |
| ExodusPoint Capital Management, LP | 0.09% | New | 75,141 | $8.0M |
| Neuberger Berman Group LLC | 0.01% | Reduce -13.6% | 73,572 | $7.9M |
| Wells Fargo & Company | 0.00% | Add +54.1% | 72,617 | $7.8M |
| Balyasny Asset Management L.P. | 0.02% | Reduce -79.3% | 72,282 | $7.7M |
| Rhumbline Advisers | 0.01% | Reduce -13.2% | 71,212 | $7.6M |
| AQR Capital Management | 0.00% | Reduce -12.2% | 70,046 | $7.5M |
| NEXTBio Capital Management LP | 4.24% | — | 67,586 | $7.2M |
| Norges Bank | 0.00% | — | 66,213 | $7.1M |
| Castleark Management LLC | 0.20% | Add +51.6% | 64,479 | $6.9M |
| Voloridge Investment Management, LLC | 0.02% | Reduce -83.5% | 60,575 | $6.5M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -2.1% | 59,609 | $6.4M |
| PDT Partners, LLC | 0.41% | Reduce -31.0% | 59,436 | $6.4M |
| Stempoint Capital LP | 1.08% | Reduce -35.6% | 58,915 | $6.3M |
| Informed Momentum Co LLC | 0.68% | Reduce -2.0% | 57,327 | $6.1M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -0.4% | 55,526 | $5.9M |
| Legal & General Group Plc | 0.00% | Reduce -4.0% | 55,075 | $5.9M |
| TD Asset Management Inc | 0.00% | Reduce -7.6% | 55,050 | $5.9M |
| California State Teachers Retirement System | 0.01% | Add +9.4% | 53,537 | $5.7M |
| Granahan Investment Management, LLC | 0.24% | Add +7.5% | 53,452 | $5.7M |
| Prudential Financial Inc. | 0.01% | Reduce -27.2% | 53,145 | $5.7M |
| ADAR1 Capital Management, LLC | 0.41% | Add +3.6% | 51,349 | $5.5M |
| Nan Fung Group Holdings Ltd | 4.71% | No change | 49,120 | $5.3M |
| Victory Capital Management Inc. | 0.00% | Add +5.8% | 45,381 | $4.9M |
| WCM Investment Management, LLC | 0.01% | Reduce -6.1% | 44,805 | $4.8M |
| Harvest Investment Services, LLC | 0.89% | Reduce -8.7% | 43,953 | $4.7M |
| HighVista Strategies LLC | 1.18% | Add +14.4% | 42,867 | $4.6M |
| Hillsdale Investment Management Inc. | 0.13% | Reduce -0.7% | 42,300 | $4.5M |
| Raymond James Financial Inc. | 0.00% | Reduce -6.8% | 41,115 | $4.4M |
| Harbor Capital Advisors, Inc. | 0.34% | Add +9.9% | 40,896 | $4.4M |
| PFM Health Sciences, LP | 0.44% | Reduce -16.5% | 40,210 | $4.3M |
| Kennedy Capital Management LLC | 0.09% | Add +0.8% | 39,887 | $4.3M |
| Sei Investments Co. | 0.00% | Add +18.2% | 37,432 | $4.0M |
| State of Wisconsin Investment Board | 0.01% | Reduce -11.5% | 36,079 | $3.9M |
| Rhenman & Partners Asset Management AB | 0.35% | No change | 35,000 | $3.7M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Add +28.7% | 34,901 | $3.7M |
| Nicholas Investment Partners, LP | 0.31% | New | 34,710 | $3.7M |
| Silvercrest Asset Management Group LLC | 0.03% | Add +0.1% | 34,127 | $3.7M |
| Squarepoint Ops LLC | 0.01% | New | 32,829 | $3.5M |
| Dimensional Fund Advisors LP | 0.00% | Add +12.8% | 32,018 | $3.4M |
| D. E. Shaw & Co. | 0.00% | Add +774.6% | 31,356 | $3.4M |
| Magnetar Financial LLC | 0.03% | New | 29,598 | $3.2M |
| EFG International AG | 0.06% | — | 29,291 | $3.1M |
| MetLife Investment Management, LLC | 0.02% | Reduce -3.9% | 29,174 | $3.1M |
| Lazard Asset Management LLC | 0.00% | Reduce -15.4% | 25,571 | $2.7M |
| Los Angeles Capital Management LLC | 0.01% | Add +45.5% | 24,334 | $2.7M |
| Creative Planning | 0.00% | Add +1.1% | 25,206 | $2.7M |
| Atom Investors LP | 0.19% | New | 22,929 | $2.5M |
| Penserra Capital Management LLC | 0.03% | Reduce -29.3% | 21,514 | $2.3M |
| Intech Investment Management LLC | 0.02% | Reduce -12.2% | 21,350 | $2.3M |
| Profund Advisors LLC | 0.07% | Add +69.0% | 21,046 | $2.3M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -7.9% | 19,270 | $2.1M |
| Wedge Capital Management L L P | 0.04% | Reduce -13.5% | 19,247 | $2.1M |
| Advisors Asset Management, Inc. | 0.03% | Add +30.6% | 18,524 | $2.0M |
| Captrust Financial Advisors | 0.00% | Add +0.4% | 18,325 | $2.0M |
| Handelsbanken Fonder AB | 0.01% | Add +12.9% | 17,521 | $1.9M |
| Arizona State Retirement System | 0.01% | Add +0.9% | 15,762 | $1.7M |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 14,650 | $1.6M |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Reduce -2.9% | 14,183 | $1.5M |
| Stifel Financial Corp. | 0.00% | Reduce -8.4% | 13,247 | $1.4M |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -0.9% | 13,139 | $1.4M |
| Citigroup Inc. | 0.00% | Reduce -2.8% | 12,720 | $1.4M |
| ProShare Advisors LLC | 0.00% | Add +11.7% | 12,622 | $1.4M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +15.9% | 12,435 | $1.3M |
| Guggenheim Capital LLC | 0.01% | Add +442.7% | 12,401 | $1.3M |
| KLP Kapitalforvaltning As | 0.01% | Add +9.1% | 12,000 | $1.3M |
| STRS Ohio | 0.00% | Reduce -18.9% | 12,000 | $1.3M |
| Rockefeller Capital Management L.P. | 0.00% | Add +32.7% | 11,771 | $1.3M |
| SG Americas Securities, LLC | 0.00% | Reduce -40.0% | 11,741 | $1.3M |
| DNB Asset Management AS | 0.00% | Add +101.9% | 11,163 | $1.2M |
| Hennion & Walsh Asset Management, Inc. | 0.04% | Reduce -75.6% | 10,908 | $1.2M |
| China Universal Asset Management Co., Ltd. | 0.09% | Reduce -6.6% | 10,875 | $1.2M |
| XTX Topco Ltd | 0.03% | New | 10,433 | $1.1M |
| Knights of Columbus Asset Advisors LLC | 0.06% | New | 10,314 | $1.1M |
| Cannon Financial Strategists, Inc. | 0.15% | No change | 10,000 | $1.1M |
| Toth Financial Advisory Corp. | 0.12% | No change | 10,000 | $1.1M |
| Man Group plc | 0.00% | Reduce -92.6% | 9,558 | $1.0M |
| Fred Alger Management, LLC | 0.00% | Reduce -24.6% | 9,301 | $996K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Add +37.3% | 9,200 | $985K |
| Headlands Technologies LLC | 0.08% | New | 8,632 | $924K |
| Teacher Retirement System of Texas | 0.00% | Reduce -35.5% | 8,359 | $895K |
| Allianz Asset Management GmbH | 0.00% | Reduce -33.9% | 8,000 | $856K |
| Bellevue Group AG | 0.02% | Reduce -17.1% | 7,504 | $803K |
| Leo Wealth, LLC | 0.05% | Reduce -11.6% | 6,952 | $744K |
| Jump Financial, LLC | 0.01% | New | 6,759 | $723K |
| E. Ohman J:or Asset Management AB | 0.02% | Reduce -19.8% | 6,589 | $705K |
| Principal Financial Group Inc. | 0.00% | Reduce -50.8% | 6,198 | $663K |
| Acadian Asset Management LLC | 0.00% | New | 6,105 | $652K |
| Exchange Traded Concepts, LLC | 0.01% | Reduce -4.8% | 6,080 | $651K |
| Virtus Investment Advisers, LLC | 0.17% | Reduce -14.7% | 6,017 | $644K |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -59.7% | 5,797 | $621K |
| Legato Capital Management LLC | 0.05% | New | 5,723 | $613K |
| Jasper Ridge Partners, L.P. | 0.01% | No change | 5,639 | $604K |
| Quantedge Capital Pte Ltd | 0.29% | Reduce -68.5% | 5,600 | $599K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 5,463 | $585K |
| LPL Financial LLC | 0.00% | Add +36.0% | 5,427 | $581K |
| AlphaCentric Advisors LLC | 0.54% | — | 5,052 | $541K |
| Voleon Capital Management LP | 0.01% | Reduce -81.3% | 5,025 | $538K |
| Two Sigma Securities, LLC | 0.07% | New | 4,943 | $529K |
| Gotham Asset Management | 0.00% | Reduce -0.1% | 4,851 | $519K |
| PSP Research LLC | 0.44% | — | 4,738 | $507K |
| PNC Financial Services Group, Inc. | 0.00% | Add +10.5% | 4,659 | $499K |
| Caption Management, LLC | 0.02% | New | 4,614 | $494K |
| Vestmark Advisory Solutions, Inc. | 0.01% | New | 4,560 | $488K |
| Verition Fund Management LLC | 0.00% | New | 4,504 | $482K |
| Mackenzie Financial Corp. | 0.00% | No change | 4,398 | $469K |
| Ameritas Investment Partners, Inc. | 0.01% | No change | 4,365 | $467K |
| Xponance LLC | 0.00% | Add +2.6% | 4,269 | $457K |
| Empowered Funds, LLC | 0.01% | Add +94.1% | 4,164 | $446K |
| Susquehanna International Group, LLP | 0.00% | Add +32.0% | 4,097 | $439K |
| Comerica Bank | 0.00% | Reduce -98.1% | 4,014 | $430K |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -96.5% | 3,859 | $413K |
| Quantinno Capital Management LP | 0.00% | Add +49.8% | 3,831 | $410K |
| Freestone Capital Holdings, LLC | 0.01% | No change | 3,700 | $396K |
| Cerity Partners LLC | 0.00% | Add +23.6% | 3,664 | $392K |
| O'shaughnessy Asset Management, LLC | 0.00% | Reduce -26.0% | 3,580 | $383K |
| Avior Wealth Management, LLC | 0.01% | Add +0.9% | 3,572 | $382K |
| Cibc World Markets Corp. | 0.00% | — | 3,502 | $375K |
| Tidal Investments LLC | 0.00% | Add +25.2% | 3,336 | $357K |
| Keybank National Association | 0.00% | New | 3,271 | $350K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +26.3% | 3,243 | $347K |
| Cinctive Capital Management LP | 0.02% | Reduce -90.8% | 3,225 | $345K |
| Yorktown Management & Research Co Inc | 0.26% | New | 3,050 | $326K |
| Cim Investment Management Inc. | 0.08% | No change | 2,993 | $320K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +69.0% | 2,962 | $317K |
| Two Sigma Advisers, LP | 0.00% | Reduce -12.1% | 2,900 | $310K |
| Blueshift Asset Management, LLC | 0.09% | New | 2,881 | $308K |
| JGP Global Gestao de Recursos Ltda. | 0.18% | Reduce -11.9% | 2,866 | $307K |
| CIBC Asset Management Inc | 0.00% | New | 2,848 | $305K |
| Cwm, LLC | 0.00% | Reduce -4.3% | 2,767 | $296K |
| Swiss Life Asset Management Ltd | 0.00% | Add +7.8% | 2,653 | $284K |
| Chicago Partners Investment Group LLC | 0.01% | Add +11.6% | 2,739 | $282K |
| AlphaGrep UK Ltd | 0.09% | — | 2,509 | $269K |
| Entropy Technologies, LP | 0.01% | Reduce -70.7% | 2,492 | $267K |
| State of Wyoming | 0.03% | Add +155.9% | 2,441 | $261K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +385.9% | 2,415 | $259K |
| Centaurus Financial, Inc. | 0.01% | No change | 2,389 | $256K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +15.0% | 2,379 | $255K |
| Abel Hall, LLC | 0.05% | New | 2,140 | $229K |
| M&T Bank Corp | 0.00% | New | 2,101 | $225K |
| Cambria Investment Management, L.P. | 0.01% | New | 1,997 | $214K |
| Elevation Wealth Partners, LLC | 0.07% | No change | 1,971 | $211K |
| Jane Street Group, LLC | 0.00% | Reduce -34.0% | 1,960 | $210K |
| KBC Group NV | 0.00% | No change | 1,707 | $183K |
| Whittier Trust Co. | 0.00% | No change | 1,811 | $180K |
| Royal Bank of Canada | 0.00% | Reduce -98.7% | 1,676 | $180K |
| Amalgamated Bank | 0.00% | Reduce -1.8% | 1,663 | $178K |
| AlphaQuest LLC | 0.01% | Add +8.4% | 1,508 | $161K |
| Persistent Asset Partners Ltd | 0.07% | New | 1,446 | $155K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -8.3% | 1,310 | $140K |
| Clearstead Advisors, LLC | 0.00% | Add +212.3% | 1,246 | $133K |
| Danske Bank A/S | 0.00% | New | 1,100 | $118K |
| Osaic Holdings, Inc. | 0.00% | Add +6.0% | 1,039 | $111K |
| US Bancorp \de | 0.00% | Add +552.7% | 953 | $102K |
| Global Retirement Partners, LLC | 0.00% | Add +114.3% | 857 | $92K |
| CFG Wealth Management Services, Inc. | 0.08% | — | 800 | $86K |
| Farther Finance Advisors, LLC | 0.00% | Add +82.9% | 642 | $69K |
| Covestor Ltd | 0.03% | Add +328.9% | 579 | $62K |
| Smartleaf Asset Management LLC | 0.00% | Add +39.5% | 399 | $43K |
| Arax Advisory Partners | 0.00% | Reduce -51.2% | 381 | $41K |
| GAMMA Investing LLC | 0.00% | Add +48.6% | 361 | $39K |
| Sterling Capital Management LLC | 0.00% | Add +170.9% | 344 | $37K |
| SBI Securities Co., Ltd. | 0.00% | Add +73.2% | 343 | $37K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +303.0% | 266 | $28K |
| Signaturefd, LLC | 0.00% | No change | 232 | $25K |
| Jones Financial Companies LLLP | 0.00% | Reduce -1.3% | 231 | $25K |
| Essential Partners LLC | 0.01% | Add +12.6% | 223 | $24K |
| Kemnay Advisory Services Inc. | 0.00% | New | 207 | $22K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -5.6% | 201 | $22K |
| True Wealth Design, LLC | 0.00% | No change | 147 | $16K |
| Truvestments Capital LLC | 0.00% | No change | 138 | $15K |
| AdvisorNet Financial, Inc | 0.00% | Add +30.5% | 137 | $15K |
| Bayforest Capital Ltd | 0.01% | Reduce -88.6% | 134 | $14K |
| Basecamp Wealth Advisors LLC | 0.00% | — | 125 | $13K |
| Allworth Financial LP | 0.00% | Reduce -16.8% | 109 | $12K |
| Optiver Holding B.V. | 0.00% | Reduce -74.8% | 92 | $10K |
| Rothschild Investment LLC | 0.00% | Add +7.1% | 91 | $10K |
| Quarry LP | 0.00% | New | 77 | $8K |
| Larson Financial Group LLC | 0.00% | Add +175.0% | 77 | $8K |
| Bessemer Group Inc. | 0.00% | No change | 66 | $7K |
| WPG Advisers, LLC | 0.00% | Add +5.3% | 60 | $6K |
| Harbour Investments, Inc. | 0.00% | New | 60 | $6K |
| Eastern Bank | 0.00% | New | 59 | $6K |
| Root Financial Partners, LLC | 0.00% | New | 43 | $5K |
| ORG Partners LLC | 0.00% | Add +15.6% | 37 | $4K |
| Versant Capital Management, Inc | 0.00% | No change | 36 | $4K |
| IFP Advisors, Inc | 0.00% | Add +89.5% | 36 | $4K |
| Parkside Financial Bank & Trust | 0.00% | No change | 33 | $4K |
| SageView Advisory Group, LLC | 0.00% | New | 30 | $3K |
| First Horizon Corp. | 0.00% | New | 30 | $3K |
| Parallel Advisors, LLC | 0.00% | No change | 25 | $3K |
| Bare Financial Services, Inc | 0.00% | Add +22.2% | 22 | $2K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 16 | $2K |
| Rakuten Securities, Inc. | 0.00% | New | 15 | $2K |
| CVA Family Office, LLC | 0.00% | No change | 12 | $1K |
| JFS Wealth Advisors, LLC | 0.00% | New | 10 | $1K |
| Keating Financial Advisory Services, Inc. | 0.00% | — | 9 | $963 |
| Fortitude Family Office, LLC | 0.00% | New | 6 | $642 |
| Toronto Dominion Bank | 0.00% | New | 6 | $642 |
| DiNuzzo Private Wealth, Inc. | 0.00% | New | 3 | $322 |
| HFM Investment Advisors, LLC | 0.00% | New | 2 | $215 |
| MAI Capital Management | 0.00% | Reduce -99.9% | 2 | $215 |
| SJS Investment Consulting Inc. | 0.00% | New | 2 | $215 |
| Rialto Wealth Management, LLC | 0.00% | New | 1 | $108 |
| TD Private Client Wealth LLC | 0.00% | New | 1 | $107 |
| Bay Harbor Wealth Management, LLC | 0.00% | New | 1 | $107 |
| Dunhill Financial, LLC | 0.00% | New | 1 | $65 |
| Avion Wealth | 0.00% | New | 4 | $0 |
"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.