Silence Therapeutics PLC-ADRSLN

13F holders, Q1 2024 (March 31)
64holders
5famous investors
$21.21avg. 13F price*

At the end of Q1 2024, 64 institutions reported holding Silence Therapeutics PLC-ADR (SLN) in their 13F filings. The largest holders were TCG Crossover Management, LLC ($71.2M), Artal Group S.A. ($60.0M) and Lombard Odier Asset Management (Europe) Ltd ($48.3M). 5 famous investors held it, including Stanley Druckenmiller (0.2% of Duquesne Family Office's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Silence Therapeutics PLC-ADR
CUSIP
82686Q101
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080 Q1 2024: 64Q1 2024Q2 2024: 71Q2 2024Q3 2024: 69Q3 2024Q4 2024: 65Q4 2024Q1 2025: 59Q1 2025Q2 2025: 55Q2 2025Q3 2025: 54Q3 2025Q4 2025: 58Q4 2025Q1 2026: 56Q1 2026Q2 2026: 72Q2 2026

Total Exit/New Position Q1 2024

InstitutionsTotal Value
New Positions32$186.8M
Exits2$26.2M

Ownership 64 holders

TCG Crossover Management, LLC 5.63% Add +56.6% 3,295,350 $71.2M
Artal Group S.A. 1.55% Reduce -7.3% 2,779,619 $60.0M
Lombard Odier Asset Management (Europe) Ltd 4.76% Reduce -38.0% 2,238,039 $48.3M
Redmile Group, LLC 1.61% New 2,027,669 $43.8M
Lombard Odier Asset Management (USA) Corp 6.14% Reduce -38.4% 2,388,912 $41.6M
Deep Track Capital, LP 1.02% Reduce -15.8% 1,643,881 $35.5M
Logos Global Management LP 3.27% Add +269.0% 1,476,061 $31.1M
Frazier Life Sciences Management, L.P. 1.05% Add +30.4% 1,148,591 $24.8M
Vivo Capital, LLC 1.88% Add +116.7% 1,105,454 $23.9M
Nextech Invest Ltd. 3.26% New 952,400 $20.6M
Janus Henderson Group PLC 0.01% New 625,864 $13.6M
Cormorant Asset Management, LP 0.59% New 625,000 $13.5M
Adage Capital Partners Gp, L.L.C. 0.02% New 600,000 $13.0M
Aquilo Capital Management, LLC 9.30% Reduce -45.0% 574,214 $12.4M
Lynx1 Capital Management LP 2.93% Add +123.3% 526,642 $11.4M
Polar Capital Holdings Plc 0.06% New 500,000 $10.8M
5AM Venture Management, LLC 2.30% New 476,200 $10.3M
Millennium Management 0.01% New 409,418 $8.8M
Duquesne Family Office 0.22% New 387,400 $8.4M
Mangrove Partners Im, LLC 0.72% New 385,408 $8.3M
Octagon Capital Advisors LP 0.83% New 315,000 $6.8M
M28 Capital Management LP 4.78% Reduce -17.7% 299,400 $6.5M
Hudson Bay Capital Management LP 0.06% New 276,590 $6.0M
Parkman Healthcare Partners LLC 0.65% Add +5.0% 244,471 $5.3M
Morgan Stanley 0.00% Add +286.5% 242,770 $5.2M
Woodline Partners LP 0.05% Add +383.8% 238,380 $5.1M
Nantahala Capital Management, LLC 0.43% New 200,000 $4.3M
HSBC Holdings PLC 0.00% No change 177,834 $3.8M
Marshall Wace, LLP 0.01% New 139,191 $3.0M
Schonfeld Strategic Advisors LLC 0.02% Add +170.3% 133,000 $2.9M
Boothbay Fund Management, LLC 0.09% New 127,224 $2.7M
Two Sigma Investments, LP 0.01% New 107,212 $2.3M
Renaissance Technologies 0.00% Add +283.4% 103,900 $2.2M
Cantor Fitzgerald, L. P. 0.54% Reduce -29.5% 103,483 $2.2M
Walleye Capital LLC 0.02% New 91,819 $2.0M
BIT Capital GmbH 0.17% New 89,000 $1.9M
Two Sigma Advisers, LP 0.00% New 77,400 $1.7M
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.05% Reduce -22.5% 72,223 $1.6M
UBS Group AG 0.00% Add +2.8% 71,918 $1.6M
Citigroup Inc. 0.00% No change 58,333 $1.3M
Artia Global Partners LP 0.28% New 52,476 $1.1M
Citadel Advisors 0.00% Add +96.4% 42,682 $922K
ADAR1 Capital Management, LLC 0.24% Add +21000.0% 40,090 $866K
Cubist Systematic Strategies, LLC 0.01% New 36,281 $784K
Blair William & Co. 0.00% Reduce -0.5% 25,432 $549K
Geode Capital Management, LLC 0.00% No change 22,427 $484K
Goldman Sachs Group Inc. 0.00% New 21,739 $470K
Trexquant Investment LP 0.01% New 21,047 $455K
Rathbones Group PLC 0.00% New 19,906 $430K
Jump Financial, LLC 0.01% New 18,800 $406K
Shay Capital LLC 0.10% New 15,150 $327K
Bank of America Corp. 0.00% Add +1014.5% 11,992 $259K
NEOS Investment Management LLC 0.02% New 11,656 $252K
Osaic Holdings, Inc. 0.00% New 10,922 $236K
JPMorgan Chase & Co. 0.00% New 9,610 $208K
Point72 Asset Management 0.00% New 8,200 $177K
SG Americas Securities, LLC 0.00% Add +10.5% 7,000 $151K
Barclays PLC 0.00% New 5,570 $120K
Qube Research & Technologies Ltd 0.00% Add +2114.6% 3,942 $85K
Lazard Asset Management LLC 0.00% Reduce -37.7% 1,415 $29K
Advisors Preferred, LLC 0.00% New 1,109 $24K
GAMMA Investing LLC 0.00% Reduce -4.6% 876 $19K
Steward Partners Investment Advisory, LLC 0.00% No change 100 $2K
Rhumbline Advisers 0.00% Add +200.0% 15 $324

"% of holder's portfolio" is SLN's weight in each manager's 13F, not the share of Silence Therapeutics PLC-ADR the manager owns.