Silence Therapeutics PLC-ADRSLN
13F holders, Q3 2024 (September 30)69holders −2
12new positions
15sold out
4famous investors
$17.49avg. 13F price*
At the end of Q3 2024, 69 institutions reported holding Silence Therapeutics PLC-ADR (SLN) in their 13F filings, down 2 from Q2 2024. 12 opened new positions and 15 sold out. The largest holders were TCG Crossover Management, LLC ($55.2M), Siren, L.L.C. ($51.5M) and Lombard Odier Asset Management (USA) Corp ($36.2M). 4 famous investors held it, including Stanley Druckenmiller (0.2% of Duquesne Family Office's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Silence Therapeutics PLC-ADR
- CUSIP
- 82686Q101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2024 → Q3 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 12 | $38.1M |
| Exits | 15 | $79.4M |
All 13F filers, Q2 2024 → Q3 2024: 5,049,518 shares bought and 6,911,448 shares sold, net −1,861,930 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 69 holders
| TCG Crossover Management, LLC | 4.67% | Reduce -7.9% | 3,033,560 | $55.2M |
| Siren, L.L.C. | 2.58% | — | 2,831,770 | $51.5M |
| Lombard Odier Asset Management (USA) Corp | 15.66% | Add +10.7% | 2,664,077 | $36.2M |
| Redmile Group, LLC | 2.03% | Reduce -5.7% | 1,899,317 | $34.5M |
| Frazier Life Sciences Management, L.P. | 0.84% | No change | 1,148,591 | $20.9M |
| Millennium Management | 0.02% | Add +41.8% | 1,110,230 | $20.2M |
| Vivo Capital, LLC | 1.66% | No change | 1,105,454 | $20.1M |
| Janus Henderson Group PLC | 0.01% | Add +32.8% | 1,087,228 | $19.8M |
| Deep Track Capital, LP | 0.58% | Reduce -26.5% | 1,000,000 | $18.2M |
| Polar Capital Holdings Plc | 0.09% | Add +6.4% | 1,000,000 | $18.2M |
| Nextech Invest Ltd. | 2.43% | No change | 952,400 | $17.3M |
| Morgan Stanley | 0.00% | Add +137.3% | 721,417 | $13.1M |
| Eventide Asset Management, LLC | 0.20% | New | 640,000 | $11.6M |
| Parkman Healthcare Partners LLC | 1.16% | Add +71.8% | 497,870 | $9.1M |
| Saturn V Capital Management LP | 3.13% | New | 481,127 | $8.7M |
| 5AM Venture Management, LLC | 1.79% | No change | 476,200 | $8.7M |
| Point72 Asset Management | 0.03% | Add +219.3% | 467,800 | $8.5M |
| Citadel Advisors | 0.01% | Add +274.0% | 436,697 | $7.9M |
| Woodline Partners LP | 0.06% | Add +347.8% | 406,903 | $7.4M |
| Cormorant Asset Management, LP | 0.39% | Reduce -36.0% | 400,000 | $7.3M |
| Duquesne Family Office | 0.25% | No change | 387,400 | $7.0M |
| Mangrove Partners Im, LLC | 0.69% | No change | 385,408 | $7.0M |
| SG Americas Securities, LLC | 0.02% | Reduce 0.0% | 343,190 | $6.2M |
| ExodusPoint Capital Management, LP | 0.06% | New | 338,681 | $6.2M |
| Cantor Fitzgerald, L. P. | 0.56% | Add +34.8% | 334,192 | $6.1M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | Reduce -46.7% | 320,000 | $5.8M |
| Aquilo Capital Management, LLC | 6.49% | Reduce -36.6% | 317,214 | $5.8M |
| Soleus Capital Management, L.P. | 0.39% | New | 260,000 | $4.7M |
| T. Rowe Price Associates Inc. | 0.00% | New | 228,644 | $4.2M |
| Logos Global Management LP | 0.41% | Reduce -86.5% | 200,000 | $3.6M |
| Nantahala Capital Management, LLC | 0.31% | No change | 200,000 | $3.6M |
| Ikarian Capital, LLC | 1.05% | Add +15.9% | 587,343 | $3.4M |
| M28 Capital Management LP | 3.70% | No change | 185,100 | $3.4M |
| HSBC Holdings PLC | 0.00% | No change | 177,834 | $3.2M |
| Boothbay Fund Management, LLC | 0.10% | Add +16.6% | 171,155 | $3.1M |
| Two Sigma Investments, LP | 0.01% | Add +70.9% | 169,392 | $3.1M |
| Marshall Wace, LLP | 0.00% | Add +12.7% | 168,417 | $3.1M |
| Schonfeld Strategic Advisors LLC | 0.02% | Add +121.2% | 166,000 | $3.0M |
| BIT Capital GmbH | 0.16% | Reduce -8.7% | 92,429 | $1.7M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.04% | Add +11.5% | 85,701 | $1.6M |
| Two Sigma Advisers, LP | 0.00% | Add +9.3% | 83,300 | $1.5M |
| UBS Group AG | 0.00% | Reduce -4.3% | 70,661 | $1.3M |
| Bank of Montreal | 0.00% | New | 65,259 | $1.2M |
| Citigroup Inc. | 0.00% | No change | 58,333 | $1.1M |
| Artia Global Partners LP | 0.27% | No change | 52,476 | $954K |
| NEOS Investment Management LLC | 0.03% | Add +39.1% | 51,712 | $940K |
| Cubist Systematic Strategies, LLC | 0.01% | Add +390.6% | 46,305 | $842K |
| ADAR1 Capital Management, LLC | 0.12% | No change | 40,290 | $732K |
| TD Asset Management Inc | 0.00% | New | 30,600 | $558K |
| Goldman Sachs Group Inc. | 0.00% | Add +88.4% | 30,632 | $557K |
| Geode Capital Management, LLC | 0.00% | No change | 29,417 | $535K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | Add +22.9% | 21,078 | $383K |
| Blair William & Co. | 0.00% | Reduce -21.4% | 20,000 | $364K |
| Qube Research & Technologies Ltd | 0.00% | New | 19,196 | $349K |
| Rathbones Group PLC | 0.00% | No change | 18,421 | $335K |
| Manufacturers Life Insurance Company, The | 0.00% | New | 17,490 | $318K |
| Quantum Portfolio Management LLC | 0.14% | Reduce -2.8% | 14,415 | $262K |
| Osaic Holdings, Inc. | 0.00% | Add +2.5% | 13,159 | $239K |
| Verition Fund Management LLC | 0.00% | New | 11,390 | $207K |
| Vestcor Inc | 0.01% | No change | 8,800 | $160K |
| Virtus Advisers, LLC | 0.04% | Add +1.8% | 4,674 | $85K |
| Barclays PLC | 0.00% | Reduce -40.2% | 3,333 | $61K |
| Values First Advisors, Inc. | 0.03% | New | 3,091 | $56K |
| Royal Bank of Canada | 0.00% | Reduce -58.8% | 1,941 | $35K |
| Bank of America Corp. | 0.00% | Reduce -89.7% | 1,034 | $19K |
| GAMMA Investing LLC | 0.00% | No change | 859 | $16K |
| Rhumbline Advisers | 0.00% | Add +60.8% | 754 | $14K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 100 | $2K |
| Wells Fargo & Company | 0.00% | New | 19 | $345 |
"% of holder's portfolio" is SLN's weight in each manager's 13F, not the share of Silence Therapeutics PLC-ADR the manager owns.