Silence Therapeutics PLC-ADRSLN
13F holders, Q4 2024 (December 31)65holders −4
14new positions
20sold out
3famous investors
$6.78avg. 13F price*
At the end of Q4 2024, 65 institutions reported holding Silence Therapeutics PLC-ADR (SLN) in their 13F filings, down 4 from Q3 2024. 14 opened new positions and 20 sold out. The largest holders were TCG Crossover Management, LLC ($20.9M), Siren, L.L.C. ($19.5M) and Redmile Group, LLC ($16.5M). 3 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Silence Therapeutics PLC-ADR
- CUSIP
- 82686Q101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 14 | $4.1M |
| Exits | 20 | $110.4M |
All 13F filers, Q3 2024 → Q4 2024: 4,908,008 shares bought and 8,289,111 shares sold, net −3,381,103 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 65 holders
| TCG Crossover Management, LLC | 2.04% | No change | 3,033,560 | $20.9M |
| Siren, L.L.C. | 0.86% | No change | 2,831,770 | $19.5M |
| Redmile Group, LLC | 1.15% | Add +26.3% | 2,399,317 | $16.5M |
| Morgan Stanley | 0.00% | Add +130.5% | 1,663,068 | $11.4M |
| Lombard Odier Asset Management (USA) Corp | 4.45% | Reduce -30.3% | 1,856,023 | $10.2M |
| Frazier Life Sciences Management, L.P. | 0.33% | No change | 1,148,591 | $7.9M |
| Vivo Capital, LLC | 0.85% | No change | 1,105,454 | $7.6M |
| Nantahala Capital Management, LLC | 0.51% | Add +424.8% | 1,049,676 | $7.2M |
| Nextech Invest Ltd. | 1.06% | No change | 952,400 | $6.6M |
| Eventide Asset Management, LLC | 0.08% | No change | 640,000 | $4.4M |
| Point72 Asset Management | 0.01% | Add +35.3% | 633,100 | $4.4M |
| Cantor Fitzgerald, L. P. | 0.14% | Add +61.5% | 539,726 | $3.7M |
| Bank of America Corp. | 0.00% | Add +48165.6% | 499,066 | $3.4M |
| Woodline Partners LP | 0.02% | Add +22.6% | 498,732 | $3.4M |
| Parkman Healthcare Partners LLC | 0.45% | Reduce -1.4% | 491,080 | $3.4M |
| Marshall Wace, LLP | 0.00% | Add +190.3% | 488,889 | $3.4M |
| 5AM Venture Management, LLC | 0.78% | No change | 476,200 | $3.3M |
| Millennium Management | 0.00% | Reduce -57.4% | 473,552 | $3.3M |
| Saturn V Capital Management LP | 1.06% | Reduce -17.9% | 395,024 | $2.7M |
| Aquilo Capital Management, LLC | 4.33% | Add +15.8% | 367,214 | $2.5M |
| UBS Group AG | 0.00% | Add +403.9% | 356,071 | $2.4M |
| Boothbay Fund Management, LLC | 0.08% | Add +105.4% | 351,527 | $2.4M |
| SG Americas Securities, LLC | 0.01% | Reduce -7.5% | 317,628 | $2.2M |
| Citadel Advisors | 0.00% | Reduce -35.3% | 282,737 | $1.9M |
| BlackRock, Inc. | 0.00% | New | 211,507 | $1.5M |
| Integral Health Asset Management, LLC | 0.12% | New | 200,000 | $1.4M |
| M28 Capital Management LP | 1.25% | No change | 185,100 | $1.3M |
| HSBC Holdings PLC | 0.00% | Reduce -2.8% | 172,834 | $1.2M |
| Two Sigma Investments, LP | 0.00% | Reduce -16.1% | 142,052 | $977K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.02% | Add +50.5% | 128,990 | $887K |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -25.8% | 123,200 | $848K |
| Cubist Systematic Strategies, LLC | 0.01% | Add +129.6% | 106,320 | $731K |
| Two Sigma Advisers, LP | 0.00% | Add +18.6% | 98,800 | $680K |
| Bank of Montreal | 0.00% | Reduce -0.4% | 65,007 | $447K |
| Trexquant Investment LP | 0.01% | New | 63,663 | $438K |
| Citigroup Inc. | 0.00% | Add +3.7% | 60,502 | $416K |
| Qube Research & Technologies Ltd | 0.00% | Add +185.2% | 54,746 | $377K |
| Osaic Holdings, Inc. | 0.00% | Add +210.6% | 40,867 | $281K |
| Goldman Sachs Group Inc. | 0.00% | Add +20.4% | 36,885 | $254K |
| Walleye Capital LLC | 0.00% | New | 36,397 | $250K |
| Geode Capital Management, LLC | 0.00% | No change | 29,417 | $202K |
| Verition Fund Management LLC | 0.00% | Add +111.8% | 24,123 | $166K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | Add +0.7% | 21,217 | $146K |
| Commonwealth of Pennsylvania Public School Empls Retrmt SYS | 0.00% | New | 19,467 | $134K |
| Acadian Asset Management LLC | 0.00% | New | 19,467 | $133K |
| Rathbones Group PLC | 0.00% | No change | 18,421 | $127K |
| ADAR1 Capital Management, LLC | 0.03% | Reduce -55.3% | 18,000 | $124K |
| FNY Investment Advisers, LLC | 0.06% | New | 17,515 | $120K |
| Ameriprise Financial Inc. | 0.00% | New | 16,360 | $113K |
| Quantum Portfolio Management LLC | 0.04% | Reduce -17.7% | 11,861 | $82K |
| Virtus Advisers, LLC | 0.03% | Add +130.5% | 10,772 | $74K |
| China Universal Asset Management Co., Ltd. | 0.01% | New | 9,963 | $69K |
| Barclays PLC | 0.00% | Add +83.8% | 6,126 | $42K |
| GAMMA Investing LLC | 0.00% | Add +609.2% | 6,092 | $42K |
| JPMorgan Chase & Co. | 0.00% | New | 3,793 | $26K |
| BNP Paribas Financial Markets | 0.00% | New | 1,784 | $12K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | New | 1,566 | $11K |
| Royal Bank of Canada | 0.00% | Reduce -21.9% | 1,515 | $10K |
| GF Fund Management Co. LTD. | 0.00% | — | 987 | $7K |
| Rhumbline Advisers | 0.00% | Add +11.5% | 841 | $6K |
| Tower Research Capital LLC (TRC) | 0.00% | New | 632 | $4K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 100 | $688 |
| SBI Securities Co., Ltd. | 0.00% | — | 28 | $193 |
| Wells Fargo & Company | 0.00% | No change | 19 | $131 |
| Simplex Trading, LLC | 0.00% | New | 51 | $0 |
"% of holder's portfolio" is SLN's weight in each manager's 13F, not the share of Silence Therapeutics PLC-ADR the manager owns.