Silence Therapeutics PLC-ADRSLN
13F holders, Q1 2026 (March 31)56holders −2
5new positions
6sold out
3famous investors
$5.13avg. 13F price*
At the end of Q1 2026, 56 institutions reported holding Silence Therapeutics PLC-ADR (SLN) in their 13F filings, down 2 from Q4 2025. 5 opened new positions and 6 sold out. The largest holders were TCG Crossover Management, LLC ($16.0M), Siren, L.L.C. ($15.3M) and Redmile Group, LLC ($11.4M). 3 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Silence Therapeutics PLC-ADR
- CUSIP
- 82686Q101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 5 | $615K |
| Exits | 6 | $8.7M |
All 13F filers, Q4 2025 → Q1 2026: 3,557,094 shares bought and 2,022,370 shares sold, net +1,534,724 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 56 holders
| TCG Crossover Management, LLC | 0.46% | No change | 3,033,560 | $16.0M |
| Siren, L.L.C. | 0.43% | No change | 2,911,438 | $15.3M |
| Redmile Group, LLC | 0.76% | No change | 2,164,777 | $11.4M |
| Nantahala Capital Management, LLC | 0.71% | Add +39.2% | 2,146,731 | $11.3M |
| Citadel Advisors | 0.00% | Add +405.9% | 1,234,807 | $6.5M |
| Millennium Management | 0.00% | Add +62.9% | 1,074,191 | $5.7M |
| Great Point Partners LLC | 1.32% | Add +26.3% | 1,020,489 | $5.4M |
| Nextech Invest Ltd. | 0.35% | No change | 952,400 | $5.0M |
| Tetragon Partners GP Ltd | 0.65% | Add +72.5% | 630,161 | $3.3M |
| 5AM Venture Management, LLC | 0.70% | No change | 476,200 | $2.5M |
| Ikarian Capital, LLC | 0.25% | No change | 865,784 | $1.7M |
| Jones Hill Capital LP | 0.34% | — | 301,604 | $1.6M |
| SG Americas Securities, LLC | 0.00% | Add +11.8% | 286,698 | $1.5M |
| UBS Group AG | 0.00% | Add +19.0% | 246,937 | $1.3M |
| Boothbay Fund Management, LLC | 0.03% | No change | 209,088 | $1.1M |
| BlackRock, Inc. | 0.00% | Add +179.9% | 204,777 | $1.1M |
| Bank of Montreal | 0.00% | Add +26.4% | 202,901 | $1.1M |
| ADAR1 Capital Management, LLC | 0.06% | Add +628.1% | 172,157 | $907K |
| Marshall Wace, LLP | 0.00% | Add +8.9% | 169,616 | $894K |
| Seven Fleet Capital Management LP | 0.26% | Add +6.2% | 156,759 | $826K |
| BNP Paribas Financial Markets | 0.00% | Add +1127.8% | 147,668 | $778K |
| Ishara Investments LP | 0.75% | Reduce -41.5% | 140,500 | $740K |
| HSBC Holdings PLC | 0.00% | Reduce -28.9% | 122,834 | $640K |
| Point72 Asset Management | 0.00% | Add +5.0% | 119,711 | $631K |
| Susquehanna International Group, LLP | 0.00% | Add +583.5% | 115,281 | $608K |
| XTX Topco Ltd | 0.01% | Add +804.6% | 106,002 | $559K |
| Qube Research & Technologies Ltd | 0.00% | Add +199.1% | 104,555 | $551K |
| M28 Capital Management LP | 0.99% | Reduce -45.3% | 101,203 | $533K |
| Jane Street Group, LLC | 0.00% | Add +246.0% | 100,927 | $532K |
| Squarepoint Ops LLC | 0.00% | New | 89,469 | $472K |
| Morgan Stanley | 0.00% | Reduce -79.8% | 65,486 | $345K |
| Goldman Sachs Group Inc. | 0.00% | Add +189.9% | 52,511 | $277K |
| Bank of America Corp. | 0.00% | Add +903.8% | 29,773 | $157K |
| Geode Capital Management, LLC | 0.00% | No change | 29,538 | $156K |
| Raymond James Financial Inc. | 0.00% | No change | 25,000 | $132K |
| Two Sigma Investments, LP | 0.00% | Reduce -58.8% | 16,203 | $85K |
| Rhumbline Advisers | 0.00% | Add +7.2% | 13,935 | $73K |
| HRT Financial LP | 0.00% | New | 11,994 | $63K |
| Dynamic Technology Lab Private Ltd | 0.01% | New | 10,490 | $55K |
| GAMMA Investing LLC | 0.00% | Reduce -7.4% | 9,365 | $49K |
| China Universal Asset Management Co., Ltd. | 0.00% | Reduce -39.0% | 8,335 | $44K |
| JPMorgan Chase & Co. | 0.00% | Reduce -3.9% | 7,636 | $38K |
| Acadian Asset Management LLC | 0.00% | New | 4,818 | $25K |
| Barclays PLC | 0.00% | Reduce -42.0% | 2,937 | $15K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +7.4% | 2,450 | $13K |
| Jones Financial Companies LLLP | 0.00% | No change | 2,500 | $12K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -5.5% | 2,313 | $12K |
| Citigroup Inc. | 0.00% | Add +13.2% | 1,835 | $10K |
| Parallel Advisors, LLC | 0.00% | No change | 1,300 | $7K |
| GF Fund Management Co. LTD. | 0.00% | Add +13.6% | 1,047 | $6K |
| Simplex Trading, LLC | 0.00% | Reduce -84.7% | 612 | $3K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 100 | $527 |
| Rockefeller Capital Management L.P. | 0.00% | No change | 45 | $237 |
| SBI Securities Co., Ltd. | 0.00% | No change | 28 | $148 |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 3 | $16 |
| Royal Bank of Canada | 0.00% | No change | 16 | $0 |
"% of holder's portfolio" is SLN's weight in each manager's 13F, not the share of Silence Therapeutics PLC-ADR the manager owns.