Silence Therapeutics PLC-ADRSLN
13F holders, Q1 2025 (March 31)59holders −6
5new positions
11sold out
3famous investors
$2.77avg. 13F price*
At the end of Q1 2025, 59 institutions reported holding Silence Therapeutics PLC-ADR (SLN) in their 13F filings, down 6 from Q4 2024. 5 opened new positions and 11 sold out. The largest holders were TCG Crossover Management, LLC ($8.6M), Siren, L.L.C. ($7.9M) and Redmile Group, LLC ($6.2M). 3 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Silence Therapeutics PLC-ADR
- CUSIP
- 82686Q101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 5 | $291K |
| Exits | 11 | $9.5M |
All 13F filers, Q4 2024 → Q1 2025: 1,304,578 shares bought and 4,205,489 shares sold, net −2,900,911 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 59 holders
| TCG Crossover Management, LLC | 1.17% | No change | 3,033,560 | $8.6M |
| Siren, L.L.C. | 0.44% | Reduce -1.5% | 2,789,833 | $7.9M |
| Redmile Group, LLC | 0.59% | Reduce -7.7% | 2,214,947 | $6.2M |
| Morgan Stanley | 0.00% | Add +20.3% | 2,000,105 | $5.6M |
| Lombard Odier Asset Management (USA) Corp | 1.69% | Reduce -0.3% | 1,849,734 | $4.0M |
| Frazier Life Sciences Management, L.P. | 0.15% | No change | 1,148,591 | $3.2M |
| Vivo Capital, LLC | 0.41% | No change | 1,105,454 | $3.1M |
| Nantahala Capital Management, LLC | 0.24% | Reduce -0.7% | 1,042,427 | $2.9M |
| Nextech Invest Ltd. | 0.62% | — | 952,400 | $2.7M |
| Cantor Fitzgerald, L. P. | 0.08% | Add +43.4% | 773,845 | $2.2M |
| Saturn V Capital Management LP | 1.04% | Add +85.4% | 732,463 | $2.1M |
| 5AM Venture Management, LLC | 0.51% | No change | 476,200 | $1.3M |
| Parkman Healthcare Partners LLC | 0.13% | Reduce -18.2% | 401,746 | $1.1M |
| Millennium Management | 0.00% | Reduce -16.2% | 396,862 | $1.1M |
| UBS Group AG | 0.00% | Reduce -10.3% | 319,514 | $901K |
| SG Americas Securities, LLC | 0.00% | Reduce -2.9% | 308,289 | $869K |
| Boothbay Fund Management, LLC | 0.03% | Reduce -28.9% | 250,012 | $705K |
| Marshall Wace, LLP | 0.00% | Reduce -53.3% | 228,418 | $644K |
| M28 Capital Management LP | 0.72% | No change | 185,100 | $522K |
| BlackRock, Inc. | 0.00% | Reduce -14.7% | 180,435 | $509K |
| HSBC Holdings PLC | 0.00% | No change | 172,834 | $499K |
| Bank of Montreal | 0.00% | Add +144.0% | 158,593 | $447K |
| Schonfeld Strategic Advisors LLC | 0.00% | Add +21.8% | 149,996 | $423K |
| Walleye Capital LLC | 0.00% | Add +274.1% | 136,150 | $384K |
| Woodline Partners LP | 0.00% | Reduce -73.0% | 134,492 | $379K |
| Two Sigma Investments, LP | 0.00% | Reduce -46.5% | 76,008 | $214K |
| Osaic Holdings, Inc. | 0.00% | Add +75.0% | 71,497 | $201K |
| Bank of America Corp. | 0.00% | Reduce -87.0% | 64,886 | $183K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.00% | Reduce -51.4% | 62,639 | $177K |
| Citadel Advisors | 0.00% | Reduce -77.9% | 62,441 | $176K |
| Citigroup Inc. | 0.00% | Add +0.9% | 61,071 | $172K |
| Two Sigma Advisers, LP | 0.00% | Reduce -50.2% | 49,200 | $139K |
| Shay Capital LLC | 0.04% | New | 47,728 | $135K |
| JPMorgan Chase & Co. | 0.00% | Add +833.7% | 35,414 | $100K |
| Geode Capital Management, LLC | 0.00% | No change | 29,417 | $83K |
| Jump Financial, LLC | 0.00% | New | 26,351 | $74K |
| Virtus Investment Advisers, LLC | 0.02% | New | 24,872 | $70K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -33.9% | 24,375 | $69K |
| Qube Research & Technologies Ltd | 0.00% | Reduce -65.5% | 18,913 | $53K |
| ADAR1 Capital Management, LLC | 0.01% | Add +3.6% | 18,643 | $53K |
| Rathbones Group PLC | 0.00% | No change | 18,421 | $52K |
| Point72 Asset Management | 0.00% | Reduce -97.5% | 16,032 | $45K |
| Acadian Asset Management LLC | 0.00% | Reduce -37.6% | 12,153 | $34K |
| China Universal Asset Management Co., Ltd. | 0.00% | Reduce -5.3% | 9,432 | $27K |
| Cubist Systematic Strategies, LLC | 0.00% | Reduce -93.1% | 7,364 | $21K |
| Barclays PLC | 0.00% | Add +11.9% | 6,854 | $19K |
| FNY Investment Advisers, LLC | 0.01% | Reduce -60.0% | 7,000 | $19K |
| BNP Paribas Financial Markets | 0.00% | Add +168.4% | 4,788 | $14K |
| Royal Bank of Canada | 0.00% | Add +181.4% | 4,263 | $12K |
| GAMMA Investing LLC | 0.00% | Reduce -41.6% | 3,560 | $10K |
| Jones Financial Companies LLLP | 0.00% | New | 2,500 | $9K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +274.5% | 2,367 | $7K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.5% | 1,573 | $5K |
| Rhumbline Advisers | 0.00% | Add +123.0% | 1,875 | $5K |
| Parallel Advisors, LLC | 0.00% | New | 1,300 | $4K |
| GF Fund Management Co. LTD. | 0.00% | Add +18.0% | 1,165 | $3K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 100 | $282 |
| SBI Securities Co., Ltd. | 0.00% | No change | 28 | $79 |
| Simplex Trading, LLC | 0.00% | Add +392.2% | 251 | $0 |
"% of holder's portfolio" is SLN's weight in each manager's 13F, not the share of Silence Therapeutics PLC-ADR the manager owns.