Silence Therapeutics PLC-ADRSLN
13F holders, Q3 2025 (September 30)54holders −1
6new positions
7sold out
2famous investors
$4.89avg. 13F price*
At the end of Q3 2025, 54 institutions reported holding Silence Therapeutics PLC-ADR (SLN) in their 13F filings, down 1 from Q2 2025. 6 opened new positions and 7 sold out. The largest holders were TCG Crossover Management, LLC ($15.7M), Siren, L.L.C. ($15.1M) and Redmile Group, LLC ($11.2M). 2 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Silence Therapeutics PLC-ADR
- CUSIP
- 82686Q101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 6 | $362K |
| Exits | 7 | $871K |
All 13F filers, Q2 2025 → Q3 2025: 336,057 shares bought and 391,255 shares sold, net −55,198 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 54 holders
| TCG Crossover Management, LLC | 0.77% | No change | 3,033,560 | $15.7M |
| Siren, L.L.C. | 0.59% | No change | 2,911,438 | $15.1M |
| Redmile Group, LLC | 1.09% | No change | 2,164,777 | $11.2M |
| Lombard Odier Asset Management (USA) Corp | 1.90% | Reduce -0.3% | 1,844,948 | $7.1M |
| Morgan Stanley | 0.00% | Reduce -0.3% | 1,207,724 | $6.3M |
| Vivo Capital, LLC | 0.46% | No change | 1,105,454 | $5.7M |
| Nantahala Capital Management, LLC | 0.33% | No change | 1,042,427 | $5.4M |
| Frazier Life Sciences Management, L.P. | 0.15% | No change | 970,130 | $5.0M |
| Nextech Invest Ltd. | 0.75% | No change | 952,400 | $4.9M |
| Cantor Fitzgerald, L. P. | 0.08% | Add +1.6% | 801,306 | $4.2M |
| 5AM Venture Management, LLC | 0.91% | No change | 476,200 | $2.5M |
| SG Americas Securities, LLC | 0.01% | Reduce -0.0% | 308,289 | $1.6M |
| UBS Group AG | 0.00% | Add +34.5% | 307,363 | $1.6M |
| Millennium Management | 0.00% | Add +50.3% | 298,512 | $1.5M |
| Boothbay Fund Management, LLC | 0.04% | Add +10.8% | 279,637 | $1.5M |
| Ikarian Capital, LLC | 0.26% | Add +3.1% | 900,784 | $1.3M |
| M28 Capital Management LP | 1.41% | No change | 185,100 | $961K |
| HSBC Holdings PLC | 0.00% | Add +0.0% | 172,873 | $909K |
| Bank of Montreal | 0.00% | Add +5.5% | 153,782 | $798K |
| Marshall Wace, LLP | 0.00% | Reduce -52.7% | 83,219 | $432K |
| Two Sigma Investments, LP | 0.00% | Add +6.6% | 63,247 | $328K |
| Woodline Partners LP | 0.00% | No change | 62,459 | $324K |
| BlackRock, Inc. | 0.00% | Reduce -63.3% | 61,832 | $321K |
| Osaic Holdings, Inc. | 0.00% | Reduce -10.4% | 62,171 | $299K |
| Two Sigma Advisers, LP | 0.00% | Add +7.6% | 42,600 | $221K |
| Geode Capital Management, LLC | 0.00% | No change | 29,538 | $153K |
| Goldman Sachs Group Inc. | 0.00% | New | 22,644 | $118K |
| Citadel Advisors | 0.00% | New | 21,505 | $112K |
| Virtus Investment Advisers, LLC | 0.03% | Add +21.0% | 20,374 | $106K |
| ADAR1 Capital Management, LLC | 0.01% | No change | 18,643 | $97K |
| HRT Financial LP | 0.00% | New | 10,887 | $56K |
| EHP Funds Inc. | 0.07% | New | 10,673 | $55K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | No change | 10,194 | $53K |
| GAMMA Investing LLC | 0.00% | Add +19.0% | 9,915 | $51K |
| China Universal Asset Management Co., Ltd. | 0.00% | Reduce -12.8% | 8,232 | $43K |
| JPMorgan Chase & Co. | 0.00% | Add +6.6% | 7,766 | $40K |
| Wexford Capital LP | 0.01% | Reduce -71.6% | 7,708 | $40K |
| Barclays PLC | 0.00% | Add +1.4% | 7,136 | $37K |
| Rhumbline Advisers | 0.00% | Reduce -5.3% | 5,865 | $30K |
| Acadian Asset Management LLC | 0.00% | New | 4,218 | $21K |
| Bank of America Corp. | 0.00% | Reduce -30.7% | 3,531 | $18K |
| Jones Financial Companies LLLP | 0.00% | No change | 2,500 | $14K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +0.8% | 2,447 | $13K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -0.1% | 1,816 | $9K |
| Citigroup Inc. | 0.00% | Reduce -49.0% | 1,773 | $9K |
| Parallel Advisors, LLC | 0.00% | No change | 1,300 | $7K |
| Royal Bank of Canada | 0.00% | Reduce -53.9% | 1,136 | $6K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -16.1% | 978 | $5K |
| BNP Paribas Financial Markets | 0.00% | Reduce -14.3% | 600 | $3K |
| Simplex Trading, LLC | 0.00% | Reduce -2.4% | 651 | $3K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 100 | $519 |
| Rockefeller Capital Management L.P. | 0.00% | New | 45 | $234 |
| SBI Securities Co., Ltd. | 0.00% | Add +3.6% | 29 | $151 |
| Principal Securities, Inc. | 0.00% | No change | 17 | $88 |
"% of holder's portfolio" is SLN's weight in each manager's 13F, not the share of Silence Therapeutics PLC-ADR the manager owns.