Silence Therapeutics PLC-ADRSLN

13F holders, Q2 2024 (June 30)
71holders +7
12new positions
5sold out
5famous investors
$18.44avg. 13F price*

At the end of Q2 2024, 71 institutions reported holding Silence Therapeutics PLC-ADR (SLN) in their 13F filings, up 7 from Q1 2024. 12 opened new positions and 5 sold out. The largest holders were TCG Crossover Management, LLC ($62.6M), Artal Group S.A. ($52.8M) and Redmile Group, LLC ($38.3M). 5 famous investors held it, including Stanley Druckenmiller (0.3% of Duquesne Family Office's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).

Company
Silence Therapeutics PLC-ADR
CUSIP
82686Q101
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080 Q1 2024: 64Q1 2024Q2 2024: 71Q2 2024Q3 2024: 69Q3 2024Q4 2024: 65Q4 2024Q1 2025: 59Q1 2025Q2 2025: 55Q2 2025Q3 2025: 54Q3 2025Q4 2025: 58Q4 2025Q1 2026: 56Q1 2026Q2 2026: 72Q2 2026

Total Exit/New Position Q1 2024 → Q2 2024

InstitutionsTotal Value
New Positions12$20.6M
Exits5$60.3M

All 13F filers, Q1 2024 → Q2 2024: 3,331,457 shares bought and 3,827,524 shares sold, net −496,067 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 71 holders

TCG Crossover Management, LLC 6.53% No change 3,295,350 $62.6M
Artal Group S.A. 1.36% No change 2,779,619 $52.8M
Redmile Group, LLC 2.31% Reduce -0.7% 2,014,296 $38.3M
Lombard Odier Asset Management (USA) Corp 16.18% Add +0.7% 2,405,998 $36.8M
Logos Global Management LP 3.23% No change 1,476,061 $28.0M
Deep Track Capital, LP 0.77% Reduce -17.3% 1,359,745 $25.8M
Frazier Life Sciences Management, L.P. 1.02% No change 1,148,591 $21.8M
Vivo Capital, LLC 1.94% No change 1,105,454 $21.0M
Nextech Invest Ltd. 3.04% No change 952,400 $18.1M
Polar Capital Holdings Plc 0.11% Add +88.0% 940,164 $17.9M
Janus Henderson Group PLC 0.01% Add +30.9% 818,978 $15.6M
Millennium Management 0.01% Add +91.2% 782,941 $14.9M
Cormorant Asset Management, LP 0.69% No change 625,000 $11.9M
Adage Capital Partners Gp, L.L.C. 0.02% No change 600,000 $11.4M
First Turn Management, LLC 1.66% New 537,338 $10.2M
Aquilo Capital Management, LLC 9.16% Reduce -12.9% 500,214 $9.5M
5AM Venture Management, LLC 2.02% No change 476,200 $9.0M
Duquesne Family Office 0.26% No change 387,400 $7.4M
Mangrove Partners Im, LLC 0.67% No change 385,408 $7.3M
SG Americas Securities, LLC 0.04% Add +4802.8% 343,196 $6.5M
Morgan Stanley 0.00% Add +25.2% 303,993 $5.8M
Parkman Healthcare Partners LLC 0.75% Add +18.6% 289,841 $5.5M
Cantor Fitzgerald, L. P. 0.96% Add +139.6% 247,966 $4.7M
Hudson Bay Capital Management LP 0.03% Reduce -24.8% 208,064 $4.0M
Nantahala Capital Management, LLC 0.38% No change 200,000 $3.8M
M28 Capital Management LP 4.56% Reduce -38.2% 185,100 $3.5M
HSBC Holdings PLC 0.00% No change 177,834 $3.4M
Octagon Capital Advisors LP 0.55% Reduce -44.1% 176,000 $3.3M
Ikarian Capital, LLC 1.03% New 506,665 $3.3M
Nicholas Investment Partners, LP 0.33% New 150,480 $2.9M
Marshall Wace, LLP 0.00% Add +7.3% 149,397 $2.8M
Boothbay Fund Management, LLC 0.10% Add +15.4% 146,852 $2.8M
Point72 Asset Management 0.01% Add +1686.6% 146,500 $2.8M
Stempoint Capital LP 0.70% New 124,866 $2.4M
Citadel Advisors 0.00% Add +173.6% 116,760 $2.2M
BIT Capital GmbH 0.17% Add +13.8% 101,235 $1.9M
Two Sigma Investments, LP 0.00% Reduce -7.6% 99,107 $1.9M
Woodline Partners LP 0.02% Reduce -61.9% 90,862 $1.7M
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.04% Add +6.4% 76,840 $1.5M
Two Sigma Advisers, LP 0.00% Reduce -1.6% 76,200 $1.4M
Schonfeld Strategic Advisors LLC 0.01% Reduce -43.6% 75,037 $1.4M
Walleye Capital LLC 0.02% Reduce -19.2% 74,220 $1.4M
UBS Group AG 0.00% Add +2.6% 73,806 $1.4M
Citigroup Inc. 0.00% No change 58,333 $1.1M
Artia Global Partners LP 0.26% No change 52,476 $997K
ADAR1 Capital Management, LLC 0.15% Add +0.5% 40,290 $766K
Renaissance Technologies 0.00% Reduce -62.4% 39,100 $743K
NEOS Investment Management LLC 0.03% Add +218.8% 37,164 $706K
Geode Capital Management, LLC 0.00% Add +31.2% 29,417 $559K
Blair William & Co. 0.00% No change 25,432 $483K
New York State Common Retirement Fund 0.00% New 24,066 $457K
Trexquant Investment LP 0.01% Add +3.6% 21,803 $414K
Legato Capital Management LLC 0.05% New 19,800 $376K
Rathbones Group PLC 0.00% Reduce -7.5% 18,421 $350K
Y-Intercept (Hong Kong) Ltd 0.02% New 17,155 $326K
Goldman Sachs Group Inc. 0.00% Reduce -25.2% 16,256 $309K
Quantum Portfolio Management LLC 0.16% New 14,836 $282K
Osaic Holdings, Inc. 0.00% Add +17.6% 12,841 $244K
Jump Financial, LLC 0.00% Reduce -34.4% 12,342 $234K
Bank of America Corp. 0.00% Reduce -16.5% 10,012 $190K
Cubist Systematic Strategies, LLC 0.00% Reduce -74.0% 9,438 $179K
Vestcor Inc 0.01% New 8,800 $167K
Quarry LP 0.05% New 6,000 $114K
Barclays PLC 0.00% No change 5,570 $106K
Advisors Preferred, LLC 0.02% Add +379.3% 5,315 $100K
Royal Bank of Canada 0.00% New 4,716 $89K
Virtus Advisers, LLC 0.04% New 4,591 $87K
GAMMA Investing LLC 0.00% Reduce -1.9% 859 $16K
Rhumbline Advisers 0.00% Add +3026.7% 469 $9K
Steward Partners Investment Advisory, LLC 0.00% No change 100 $2K
Lazard Asset Management LLC 0.00% Reduce -95.8% 60 $1K

"% of holder's portfolio" is SLN's weight in each manager's 13F, not the share of Silence Therapeutics PLC-ADR the manager owns.