Xenon PharmaceuticalsXENE

13F holders, Q1 2024 (March 31)
220holders
7famous investors
$43.05avg. 13F price*

At the end of Q1 2024, 220 institutions reported holding Xenon Pharmaceuticals Inc. (XENE) in their 13F filings. The largest holders were FMR LLC ($284.2M), Avoro Capital Advisors LLC ($243.9M) and Driehaus Capital Management LLC ($186.1M). 7 famous investors held it, including Ken Griffin (0.1% of Citadel Advisors's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).

Company
Xenon Pharmaceuticals Inc.
CUSIP
98420N105
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400 Q1 2024: 220Q1 2024Q2 2024: 213Q2 2024Q3 2024: 203Q3 2024Q4 2024: 209Q4 2024Q1 2025: 206Q1 2025Q2 2025: 206Q2 2025Q3 2025: 219Q3 2025Q4 2025: 245Q4 2025Q1 2026: 290Q1 2026Q2 2026: 315Q2 2026

Total Exit/New Position Q1 2024

InstitutionsTotal Value
New Positions35$61.0M
Exits18$64.3M

Ownership 220 holders

FMR LLC 0.02% Add +16.7% 6,601,830 $284.2M
Avoro Capital Advisors LLC 2.85% No change 5,666,666 $243.9M
Driehaus Capital Management LLC 1.85% Reduce -0.5% 4,321,740 $186.1M
Wellington Management Group LLP 0.03% Reduce -5.8% 3,922,058 $168.8M
Capital World Investors 0.02% No change 2,681,537 $115.4M
Polar Capital Holdings Plc 0.59% Reduce -14.8% 2,612,108 $112.5M
Paradigm Biocapital Advisors LP 3.77% Add +16.8% 2,484,874 $107.0M
Capital International Investors 0.02% Add +0.8% 2,475,859 $106.6M
Commodore Capital LP 6.24% No change 2,167,793 $93.3M
BlackRock Inc. 0.00% Add +2.6% 2,121,928 $91.3M
Adage Capital Partners Gp, L.L.C. 0.14% Add +59.4% 1,671,917 $72.0M
Pictet Asset Management Holding SA 0.07% Reduce -25.7% 1,515,426 $65.2M
Alliancebernstein L.P. 0.02% Reduce -6.7% 1,468,446 $63.2M
Marshall Wace, LLP 0.10% Reduce -5.1% 1,450,342 $62.4M
T. Rowe Price Investment Management, Inc. 0.04% Add +60.1% 1,426,339 $61.4M
First Light Asset Management, LLC 4.35% Reduce -19.8% 1,320,172 $56.8M
Braidwell LP 3.17% Reduce -20.6% 1,308,011 $56.3M
Citadel Advisors 0.05% Add +1.6% 1,287,075 $55.4M
Rock Springs Capital Management LP 1.38% No change 1,255,577 $54.1M
Invesco Ltd. 0.01% Add +45.8% 1,049,526 $45.2M
Baker Bros. Advisors LP 0.54% No change 993,679 $42.8M
Janus Henderson Group PLC 0.02% Reduce -2.5% 941,569 $40.5M
Lord, Abbett & Co. LLC 0.13% Add +24.7% 895,196 $38.5M
Perceptive Advisors LLC 0.68% Reduce -18.9% 892,208 $38.4M
Affinity Asset Advisors, LLC 6.31% Add +82.0% 837,387 $36.0M
TimesSquare Capital Management, LLC 0.46% Reduce -7.2% 737,173 $31.7M
Federated Hermes, Inc. 0.07% Add +112.0% 734,900 $31.6M
Avidity Partners Management LP 1.09% Reduce -13.0% 710,000 $30.6M
Loomis Sayles & Co. L P 0.04% Reduce -3.1% 686,510 $29.6M
First Turn Management, LLC 4.38% No change 680,389 $29.3M
Boxer Capital, LLC 1.28% No change 600,000 $25.8M
Fiera Capital Corp 0.07% Add +4.3% 576,542 $24.8M
Jennison Associates LLC 0.02% Reduce -0.4% 563,952 $24.3M
Candriam S.C.A. 0.16% Add +5.7% 560,884 $24.1M
Orbimed Advisors LLC 0.43% No change 550,000 $23.7M
Franklin Resources Inc. 0.01% Add +84.6% 542,289 $23.3M
Great Point Partners LLC 3.06% Reduce -24.0% 456,148 $19.6M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.05% New 416,736 $17.9M
Dimensional Fund Advisors LP 0.00% Add +1.9% 410,207 $17.7M
Vestal Point Capital, LP 1.42% Add +128.6% 400,000 $17.2M
Samlyn Capital, LLC 0.30% Reduce -5.9% 396,196 $17.1M
Morgan Stanley 0.00% Add +71.5% 386,199 $16.6M
Altium Capital Management LLC 6.74% Add +19.8% 348,000 $15.0M
Westfield Capital Management Co. LP 0.08% Add +46.3% 347,351 $15.0M
Vanguard Group Inc. 0.00% Add +3.8% 335,635 $14.4M
Ally Bridge Group (NY) LLC 7.40% Add +27.9% 309,369 $13.3M
Goldman Sachs Group Inc. 0.00% Reduce -20.3% 299,774 $12.9M
Boone Capital Management LLC 2.54% Add +14.1% 291,403 $12.5M
Point72 Asset Management 0.04% Reduce -68.5% 275,859 $11.9M
Two Sigma Investments, LP 0.03% Reduce -19.2% 274,626 $11.8M
DAFNA Capital Management LLC 2.71% Reduce -1.1% 273,739 $11.8M
Artal Group S.A. 0.28% New 253,387 $10.9M
Granahan Investment Management, LLC 0.37% Reduce -19.3% 244,080 $10.5M
State Street Corp. 0.00% Add +6.9% 242,640 $10.4M
Laurion Capital Management LP 0.29% Add +218.8% 239,126 $10.3M
Alyeska Investment Group, L.P. 0.06% New 238,843 $10.3M
Two Sigma Advisers, LP 0.02% Reduce -9.3% 229,200 $9.9M
Parkman Healthcare Partners LLC 1.18% Reduce -24.0% 223,942 $9.6M
Tri Locum Partners LP 3.10% Reduce -8.0% 207,465 $8.9M
Balyasny Asset Management L.P. 0.02% Add +1169.8% 201,274 $8.7M
D. E. Shaw & Co. 0.01% Add +135.9% 198,526 $8.5M
New York State Common Retirement Fund 0.01% Add +1.3% 192,752 $8.3M
AXA S.A. 0.02% Add +0.0% 187,872 $8.1M
Assenagon Asset Management S.A. 0.02% Add +87.1% 186,606 $8.0M
Algert Global LLC 0.31% Reduce -15.3% 184,015 $7.9M
Russell Investments Group, Ltd. 0.01% Add +2.2% 178,099 $7.7M
Nicholas Investment Partners, LP 0.82% Add +91.4% 167,926 $7.2M
Ensign Peak Advisors, Inc 0.01% Reduce -0.8% 163,064 $7.0M
Bank of America Corp. 0.00% Add +17.8% 157,104 $6.8M
ExodusPoint Capital Management, LP 0.08% Reduce -6.8% 154,038 $6.6M
PFM Health Sciences, LP 0.33% Reduce -21.9% 150,554 $6.5M
Bridger Management, LLC 2.85% No change 146,800 $6.3M
DNB Asset Management AS 0.03% Reduce -0.1% 126,250 $5.4M
Swiss National Bank 0.00% No change 123,800 $5.3M
Atika Capital Management LLC 0.59% Add +30.9% 122,000 $5.3M
Ikarian Capital, LLC 1.25% New 107,187 $4.6M
Nan Fung Group Holdings Ltd 4.26% No change 106,680 $4.6M
Baron Capital (BAMCO) 0.01% No change 100,100 $4.3M
Twinbeech Capital LP 0.09% New 98,042 $4.2M
State of Wisconsin Investment Board 0.01% Reduce -3.7% 91,785 $4.0M
Schroder Investment Management Group 0.00% No change 91,500 $3.9M
Credit Suisse AG/ 0.00% Add +4.3% 85,339 $3.7M
Millennium Management 0.00% Add +8.7% 83,661 $3.6M
Schonfeld Strategic Advisors LLC 0.03% Reduce -8.6% 79,951 $3.4M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% No change 77,484 $3.3M
HighVista Strategies LLC 1.12% Add +40.4% 72,715 $3.1M
Bank of New York Mellon Corp 0.00% Add +0.4% 66,910 $2.9M
Silverarc Capital Management, LLC 0.80% Reduce -59.5% 66,090 $2.8M
Jefferies Financial Group Inc. 0.06% Reduce -1.6% 65,637 $2.8M
Voya Investment Management LLC 0.00% No change 64,940 $2.8M
Geode Capital Management, LLC 0.00% Add +3.5% 64,229 $2.8M
Wells Fargo & Company 0.00% Add +5.2% 61,457 $2.6M
Prudential Financial Inc. 0.00% No change 59,000 $2.5M
State of New Jersey Common Pension Fund D 0.01% Reduce -20.1% 56,750 $2.4M
California State Teachers Retirement System 0.00% Add +0.9% 56,477 $2.4M
Renaissance Technologies 0.00% Add +73.0% 56,400 $2.4M
Legal & General Group Plc 0.00% Add +2.5% 55,010 $2.4M
Moore Capital Management, LP 0.05% Reduce -15.4% 55,000 $2.4M
Alps Advisors Inc. 0.02% Add +4.8% 53,200 $2.3M
Erste Asset Management GmbH 0.03% No change 50,000 $2.1M
LMR Partners LLP 0.08% Add +4980.2% 48,668 $2.1M
Northern Trust Corp. 0.00% Reduce -21.8% 48,470 $2.1M
Envestnet Asset Management Inc. 0.00% Add +6.5% 48,177 $2.1M
Trexquant Investment LP 0.04% New 46,874 $2.0M
Jump Financial, LLC 0.05% Add +92.0% 46,079 $2.0M
Qube Research & Technologies Ltd 0.00% New 45,286 $1.9M
Nuveen Asset Management, LLC 0.00% Add +5.2% 42,473 $1.8M
Artia Global Partners LP 0.42% New 40,000 $1.7M
DekaBank Deutsche Girozentrale 0.00% No change 39,000 $1.7M
Deutsche Bank AG 0.00% Add +1451.5% 38,711 $1.7M
Cibc World Market Inc. 0.00% Reduce -1.5% 37,320 $1.6M
JPMorgan Chase & Co. 0.00% Reduce -30.6% 36,621 $1.6M
UBS Group AG 0.00% Add +17.1% 36,246 $1.6M
Royal Bank of Canada 0.00% Reduce -2.6% 35,132 $1.5M
TLS Advisors LLC 3.30% No change 32,956 $1.4M
HRT Financial LP 0.01% Reduce -60.8% 32,608 $1.4M
Aberdeen Group plc 0.00% No change 32,036 $1.4M
Cinctive Capital Management LP 0.07% Add +15.1% 31,770 $1.4M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +100.7% 31,280 $1.3M
Boothbay Fund Management, LLC 0.04% Reduce -24.6% 30,361 $1.3M
Engineers Gate Manager LP 0.03% New 26,513 $1.1M
Tudor Investment Corporation 0.01% Reduce -41.8% 25,157 $1.1M
NJ State Employees Deferred Compensation Plan 0.14% No change 25,000 $1.1M
Aquatic Capital Management LLC 0.03% Add +26.7% 24,700 $1.1M
Knott David M Jr 0.36% No change 23,866 $1.0M
Rathbones Group PLC 0.01% No change 23,666 $1.0M
Susquehanna International Group, LLP 0.00% Reduce -55.3% 23,646 $1.0M
Stifel Financial Corp. 0.00% Add +6.2% 22,175 $955K
Gsa Capital Partners LLP 0.07% New 21,614 $930K
Sanders Morris Harris LLC 0.17% No change 21,500 $926K
Chartwell Investment Partners, LLC 0.03% Add +2.4% 21,020 $905K
TD Asset Management Inc 0.00% Add +25.9% 20,430 $880K
SG Americas Securities, LLC 0.00% Add +9.5% 20,366 $877K
Natixis Advisors, LLC 0.00% Reduce -7.6% 19,676 $847K
Prelude Capital Management, LLC 0.05% Reduce -43.1% 18,311 $788K
Y-Intercept (Hong Kong) Ltd 0.06% New 18,305 $788K
Allianz Asset Management GmbH 0.00% No change 17,400 $749K
Arizona State Retirement System 0.01% Reduce -1.7% 17,261 $743K
Eisler Capital (US) LLC 0.24% New 16,654 $717K
Legato Capital Management LLC 0.08% Add +35.9% 16,085 $692K
Gilder Gagnon Howe & Co. LLC 0.01% New 15,092 $650K
China Universal Asset Management Co., Ltd. 0.08% Add +69.9% 14,520 $625K
Moody Aldrich Partners LLC 0.11% Add +58.4% 14,451 $622K
Bellevue Group AG 0.01% Reduce -35.9% 14,100 $607K
Handelsbanken Fonder AB 0.00% No change 14,100 $607K
Teacher Retirement System of Texas 0.00% Reduce -0.1% 13,977 $602K
Advisors Asset Management, Inc. 0.01% Add +31.7% 13,717 $591K
Orion Porfolio Solutions, LLC 0.01% Add +66.7% 13,698 $590K
Orion Portfolio Solutions, LLC 0.01% Add +66.7% 13,698 $590K
Assetmark, Inc. 0.00% Add +32.7% 13,185 $568K
Barclays PLC 0.00% Reduce -88.8% 12,554 $540K
Capstone Investment Advisors, LLC 0.02% Add +28.7% 11,402 $491K
Guggenheim Capital LLC 0.00% Add +19.5% 11,388 $490K
Supplemental Annuity Collective Trust of NJ 0.15% No change 11,000 $474K
Public Employees Retirement Association of Colorado 0.00% No change 10,633 $458K
CANADA LIFE ASSURANCE Co 0.00% Add +87.8% 10,032 $432K
Birchview Capital, LP 0.35% No change 10,000 $431K
Bayesian Capital Management, LP 0.04% New 9,700 $418K
American Century Companies Inc. 0.00% Add +34.1% 9,655 $416K
Entropy Technologies, LP 0.04% New 9,649 $415K
Atom Investors LP 0.05% Reduce -37.0% 9,603 $413K
17 Capital Partners, LLC 0.29% New 2,840 $392K
Jane Street Group, LLC 0.00% Reduce -71.3% 8,449 $364K
BNP Paribas Financial Markets 0.00% Add +89.5% 8,321 $358K
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.01% Reduce -45.6% 7,987 $344K
Sei Investments Co. 0.00% Reduce -2.8% 7,951 $342K
Elmwood Wealth Management, Inc. 0.15% Reduce -21.1% 7,943 $342K
Vident Advisory, LLC 0.01% Add +47.4% 7,801 $336K
Man Group plc 0.00% New 6,900 $297K
Virtu Financial LLC 0.02% New 6,661 $287K
Axq Capital, LP 0.06% Reduce -19.2% 5,662 $244K
Snowden Capital Advisors LLC 0.01% Reduce -3.9% 5,499 $237K
Oppenheimer Asset Management Inc. 0.00% Add +21.4% 5,374 $231K
ProShare Advisors LLC 0.00% Add +12.0% 5,286 $228K
Cubist Systematic Strategies, LLC 0.00% New 5,105 $220K
HighMark Wealth Management LLC 0.13% New 5,000 $215K
Northwestern Mutual Wealth Management Co. 0.00% No change 5,000 $215K
NEOS Investment Management LLC 0.01% New 4,972 $214K
Corton Capital Inc. 0.08% New 4,864 $209K
Aigen Investment Management, LP 0.05% Reduce -39.5% 4,863 $209K
EntryPoint Capital, LLC 0.18% New 4,541 $195K
Simplex Trading, LLC 0.01% Reduce -86.0% 3,977 $171K
Harbor Capital Advisors, Inc. 0.02% New 3,225 $139K
PNC Financial Services Group, Inc. 0.00% Add +35.4% 2,680 $115K
Citigroup Inc. 0.00% Reduce -19.7% 2,413 $104K
IFP Advisors, Inc 0.00% Reduce -1.3% 2,121 $91K
Virtus Advisers, LLC 0.05% Reduce -6.3% 2,103 $91K
Concourse Financial Group Securities, Inc. 0.01% No change 2,000 $86K
US Bancorp \de 0.00% Add +67.6% 1,564 $67K
Quarry LP 0.02% Add +30.0% 1,300 $56K
Tower Research Capital LLC (TRC) 0.00% Add +20.9% 1,226 $53K
Allianz SE 0.00% — 1,200 $52K
Parallel Advisors, LLC 0.00% Add +2.8% 1,157 $50K
Bank of Montreal 0.00% New 909 $39K
Osaic Holdings, Inc. 0.00% Reduce -68.9% 830 $36K
Accent Capital Management, LLC 0.01% No change 400 $17K
First Horizon Advisors, Inc. 0.00% Reduce -35.1% 370 $16K
Avior Wealth Management, LLC 0.00% New 302 $13K
State of Wyoming 0.00% New 300 $13K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% New 276 $12K
Daiwa Securities Group Inc. 0.00% No change 252 $11K
Householder Group Estate & Retirement Specialist, LLC 0.00% No change 215 $9K
EverSource Wealth Advisors, LLC 0.00% Add +256.5% 164 $7K
Signaturefd, LLC 0.00% No change 129 $6K
CVA Family Office, LLC 0.00% Add +60.6% 53 $2K
NewEdge Advisors, LLC 0.00% Reduce -25.0% 48 $2K
Whittier Trust Co. of Nevada Inc. 0.00% Reduce -5.3% 36 $2K
GAMMA Investing LLC 0.00% Add +59.1% 35 $2K
Bell Investment Advisors, Inc 0.00% New 30 $1K
Rhumbline Advisers 0.00% New 29 $1K
Blue Trust, Inc. 0.00% Reduce -77.9% 27 $1K
Park Place Capital Corp 0.00% New 18 $775
Principal Securities, Inc. 0.00% No change 16 $689
Continuum Advisory, LLC 0.00% New 15 $637
Allworth Financial LP 0.00% New 12 $517
C M Bidwell & Associates Ltd. 0.00% New 9 $387
JFS Wealth Advisors, LLC 0.00% Add +300.0% 8 $345
SJS Investment Consulting Inc. 0.00% No change 5 $216
Lindbrook Capital, LLC 0.00% New 3 $129
DiNuzzo Private Wealth, Inc. 0.00% No change 2 $87

"% of holder's portfolio" is XENE's weight in each manager's 13F, not the share of Xenon Pharmaceuticals Inc. the manager owns.