Alnylam PharmaceuticalsALNY

13F holders, Q3 2024 (September 30)
568holders +45
100new positions
58sold out
7famous investors
$275.02avg. 13F price*

At the end of Q3 2024, 568 institutions reported holding Alnylam Pharmaceuticals Inc. (ALNY) in their 13F filings, up 45 from Q2 2024. 100 opened new positions and 58 sold out. The largest holders were Capital World Investors ($4.5B), FMR LLC ($4.0B) and Vanguard Group Inc. ($3.5B). 7 famous investors held it, including Cliff Asness (0.2% of AQR Capital Management's portfolio), David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.1% of Millennium Management's portfolio).

Company
Alnylam Pharmaceuticals Inc.
Sector
Health Care
CUSIP
02043Q107
Latest filing quarter
Q2 2026

History

Number of 13F holders

02004006008001,000 Q1 2024: 498Q1 2024Q2 2024: 523Q2 2024Q3 2024: 568Q3 2024Q4 2024: 594Q4 2024Q1 2025: 626Q1 2025Q2 2025: 654Q2 2025Q3 2025: 823Q3 2025Q4 2025: 852Q4 2025Q1 2026: 793Q1 2026Q2 2026: 793Q2 2026

Total Exit/New Position Q2 2024 → Q3 2024

InstitutionsTotal Value
New Positions100$488.0M
Exits58$461.8M

All 13F filers, Q2 2024 → Q3 2024: 12,288,805 shares bought and 8,457,039 shares sold, net +3,831,766 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 568 holders

Capital World Investors 0.70% Add +10.3% 16,508,424 $4.5B
FMR LLC 0.25% Add +20.6% 14,672,272 $4.0B
Vanguard Group Inc. 0.06% Add +1.0% 12,635,096 $3.5B
BlackRock, Inc. 0.06% — 9,707,418 $2.7B
Capital Research Global Investors 0.30% Add +61.1% 5,243,903 $1.4B
Wellington Management Group LLP 0.24% Reduce -20.2% 4,953,347 $1.4B
Baillie Gifford & Co. 1.01% Reduce -19.0% 4,887,000 $1.3B
Capital International Investors 0.21% Add +2.0% 3,970,863 $1.1B
Dodge & Cox 0.56% Reduce -4.2% 3,622,535 $996.3M
State Street Corp. 0.04% Reduce -1.9% 3,468,315 $953.9M
T. Rowe Price Associates Inc. 0.11% Reduce -1.0% 3,451,833 $949.4M
T. Rowe Price Investment Management, Inc. 0.52% Reduce -0.5% 3,139,254 $863.4M
Norges Bank 0.09% Add +3.4% 2,375,535 $653.3M
JPMorgan Chase & Co. 0.05% Add +22.0% 2,162,944 $594.9M
Geode Capital Management, LLC 0.05% Add +3.2% 2,147,203 $589.2M
American Century Companies Inc. 0.26% Add +17.6% 1,592,733 $438.0M
Orbis Allan Gray Ltd 1.85% Add +75.9% 1,268,112 $348.8M
Winslow Capital Management, LLC 0.95% New 961,607 $264.5M
Bellevue Group AG 3.61% Reduce -12.0% 809,095 $222.5M
Legal & General Group Plc 0.06% Add +3.9% 791,729 $217.7M
Northern Trust Corp. 0.03% Reduce -5.9% 734,919 $202.1M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.05% Reduce -15.5% 706,231 $194.2M
Invesco Ltd. 0.04% Add +77.1% 695,868 $191.4M
Pictet Asset Management Holding SA 0.20% Reduce -12.4% 664,722 $182.8M
Morgan Stanley 0.01% Reduce -16.6% 618,563 $170.1M
Amundi 0.06% Reduce -19.5% 593,320 $160.9M
Bank of America Corp. 0.01% Reduce -12.7% 550,772 $151.5M
Deutsche Bank AG 0.06% Add +10.3% 539,271 $148.3M
Loomis Sayles & Co. L P 0.19% Reduce -7.7% 525,303 $144.5M
AQR Capital Management 0.19% Add +86.2% 505,654 $139.0M
TD Asset Management Inc 0.12% Reduce -0.3% 488,283 $134.2M
Charles Schwab Investment Management Inc. 0.03% Add +3.6% 487,348 $134.0M
Bank of New York Mellon Corp 0.02% Reduce -29.6% 474,439 $130.5M
Nuveen Asset Management, LLC 0.03% Reduce -25.0% 441,092 $121.3M
Royal Bank of Canada 0.03% Reduce -0.1% 411,066 $113.1M
Franklin Resources Inc. 0.03% Add +32.4% 382,973 $108.5M
Gilder Gagnon Howe & Co. LLC 1.26% Reduce -3.7% 383,993 $105.6M
Swiss National Bank 0.07% Add +0.3% 375,400 $103.2M
Goldman Sachs Group Inc. 0.02% Reduce -30.8% 356,100 $97.9M
Candriam S.C.A. 0.56% Add +0.1% 351,668 $96.7M
Canada Pension Plan Investment Board 0.09% Add +21.5% 344,858 $94.8M
D. E. Shaw & Co. 0.13% Add +18.9% 332,305 $91.4M
Eagle Asset Management Inc. 0.44% Add +25.7% 309,589 $85.9M
Polar Capital Holdings Plc 0.41% Add +8.8% 310,000 $85.3M
Dimensional Fund Advisors LP 0.02% Add +13.2% 301,389 $82.9M
First Trust Advisors LP 0.07% Add +18.7% 285,571 $78.5M
Royal London Asset Management Ltd. 0.19% Reduce -0.9% 279,750 $76.9M
Corient Private Wealth LP 0.12% Add +1.4% 278,485 $76.6M
Sumitomo Mitsui Trust Group, Inc. 0.05% Add +0.5% 278,241 $76.5M
Wells Fargo & Company 0.02% Add +29.3% 266,497 $73.3M
Millennium Management 0.06% Add +81.2% 250,963 $69.0M
Orbimed Advisors LLC 1.26% No change 250,300 $68.8M
Rock Springs Capital Management LP 2.24% No change 250,000 $68.8M
Sei Investments Co. 0.09% Add +507.3% 237,907 $65.4M
Eventide Asset Management, LLC 1.06% Add +157.8% 224,333 $61.7M
Janus Henderson Group PLC 0.03% Reduce -12.1% 219,337 $60.3M
California Public Employees Retirement System 0.04% Reduce -1.8% 211,781 $58.2M
CIBC Private Wealth Group LLC 0.10% Add +1.0% 208,486 $57.3M
Aberdeen Group plc 0.10% Add +0.1% 200,069 $55.0M
National Pension Service 0.05% No change 196,387 $54.0M
Voloridge Investment Management, LLC 0.19% Add +1206.9% 194,247 $53.4M
Manufacturers Life Insurance Company, The 0.05% Reduce -41.8% 191,382 $52.6M
California State Teachers Retirement System 0.06% Reduce -1.2% 191,325 $52.6M
Rhumbline Advisers 0.04% Add +4.7% 181,428 $49.9M
Casdin Capital, LLC 3.12% No change 170,000 $46.8M
Federated Hermes, Inc. 0.10% Add +82.4% 168,923 $46.5M
Susquehanna International Group, LLP 0.08% Add +144.3% 163,734 $45.0M
UBS Group AG 0.01% Reduce -0.6% 155,671 $42.8M
Qube Research & Technologies Ltd 0.08% New 152,162 $41.8M
Skandinaviska Enskilda Banken AB (publ) 0.19% Add +40.4% 150,119 $41.3M
Deerfield Management Company, L.P. 0.66% Add +21.0% 145,000 $39.9M
Palo Alto Investors LP 5.03% New 140,681 $38.7M
ANTIPODES PARTNERS Ltd 1.33% Reduce -41.6% 139,375 $38.3M
Ameriprise Financial Inc. 0.01% Reduce -42.2% 137,838 $37.9M
Los Angeles Capital Management LLC 0.15% Add +11433.4% 137,017 $37.7M
Jane Street Group, LLC 0.06% Reduce -2.3% 136,281 $37.5M
Capital International Sarl 0.95% Add +23.0% 135,073 $37.1M
State Board of Administration of Florida Retirement System 0.07% Reduce -4.4% 129,417 $35.6M
Panagora Asset Management Inc. 0.17% Add +535.5% 125,891 $34.6M
Capital International, Inc. 0.43% Add +9.9% 125,221 $34.4M
Mitsubishi UFJ Trust & Banking Corp 0.08% Reduce -55.2% 120,332 $33.1M
Novo Holdings A/S 1.62% No change 118,383 $32.6M
HighTower Advisors, LLC 0.05% Reduce -7.4% 115,790 $31.9M
Adage Capital Partners Gp, L.L.C. 0.06% Reduce -54.3% 116,000 $31.9M
BNP Paribas Financial Markets 0.03% Reduce -8.9% 114,784 $31.6M
DekaBank Deutsche Girozentrale 0.06% Reduce -0.2% 113,193 $30.9M
Frontier Capital Management Co. LLC 0.29% Reduce -34.0% 111,231 $30.6M
AXA S.A. 0.09% Add +0.2% 111,216 $30.6M
Man Group plc 0.09% Reduce -6.9% 109,803 $30.2M
Voya Investment Management LLC 0.04% Reduce -4.8% 108,709 $29.9M
Korea Investment CORP 0.07% Reduce -4.0% 107,893 $29.7M
Neuberger Berman Group LLC 0.02% Add +11.3% 106,197 $29.2M
Barclays PLC 0.01% Reduce -19.9% 105,185 $28.9M
Two Sigma Advisers, LP 0.07% Reduce -60.1% 103,100 $28.4M
Capital International Ltd. 1.19% Add +6.6% 100,423 $27.6M
Telemark Asset Management, LLC 2.78% New 100,000 $27.5M
Trexquant Investment LP 0.32% Add +139.7% 90,743 $25.0M
Nomura Asset Management Co. Ltd. 0.07% Add +7.8% 85,445 $23.5M
Mitsubishi UFJ Asset Management Co., Ltd. 0.03% Add +8.6% 85,305 $23.5M
Treasurer of the State of North Carolina 0.09% Add +6.3% 84,605 $23.3M
Prudential Financial Inc. 0.03% Add +2167.4% 82,965 $22.8M
Ensign Peak Advisors, Inc 0.04% Add +9.7% 80,568 $22.2M
State of Wisconsin Investment Board 0.05% Add +1.5% 79,094 $21.8M
Eagle Health Investments LP 4.04% No change 76,256 $21.0M
New York State Common Retirement Fund 0.03% Reduce -19.5% 76,228 $21.0M
Citigroup Inc. 0.02% Reduce -81.5% 74,271 $20.4M
Robeco Institutional Asset Management B.V. 0.04% Add +48.1% 73,568 $20.2M
Connor, Clark & Lunn Investment Management Ltd. 0.10% Add +22.4% 73,320 $20.2M
Handelsbanken Fonder AB 0.08% Add +0.2% 73,181 $20.1M
Macquarie Group Ltd. 0.02% Add +22.1% 72,616 $20.0M
CANADA LIFE ASSURANCE Co 0.03% Add +26.3% 68,713 $18.9M
Asset Management One Co., Ltd. 0.07% Add +3.4% 67,953 $18.7M
LMR Partners LLP 0.52% Add +652.3% 67,489 $18.6M
Rafferty Asset Management, LLC 0.06% Reduce -21.3% 63,831 $17.6M
Marshall Wace, LLP 0.02% New 63,467 $17.5M
Van Eck Associates Corp. 0.02% Reduce -5.8% 57,399 $16.9M
U.S. Capital Wealth Advisors, LLC 0.60% No change 61,500 $16.9M
Soleus Capital Management, L.P. 1.36% Reduce -17.1% 59,400 $16.3M
Worldquant Millennium Advisors LLC 0.12% Reduce -54.8% 58,520 $16.1M
HSBC Holdings PLC 0.01% Add +5.0% 56,870 $15.6M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.04% Reduce -16.7% 54,570 $15.0M
Swedbank AB 0.02% Add +160.3% 53,729 $14.8M
Alliancebernstein L.P. 0.00% Add +16.0% 52,624 $14.5M
Danske Bank A/S 0.05% Add +0.2% 52,405 $14.4M
Forsta Ap-Fonden 0.11% Add +102.0% 50,900 $14.0M
Rhenman & Partners Asset Management AB 1.12% Reduce -41.1% 50,350 $13.8M
Public Employees Retirement System of Ohio 0.06% Reduce -6.3% 48,437 $13.3M
State of New Jersey Common Pension Fund D 0.05% Reduce -2.1% 47,433 $13.0M
Schroder Investment Management Group 0.01% Reduce -16.5% 47,342 $13.0M
Jefferies Financial Group Inc. 0.23% Add +1951.9% 47,193 $13.0M
Victory Capital Management Inc. 0.01% Add +10.9% 42,909 $11.8M
Squarepoint Ops LLC 0.04% Reduce -56.8% 42,701 $11.7M
Capital Group Private Client Services, Inc. 0.11% Reduce -1.6% 42,449 $11.7M
Russell Investments Group, Ltd. 0.02% Add +2.8% 42,324 $11.6M
Brown Advisory Inc. 0.01% Reduce -7.6% 39,123 $10.8M
Resona Asset Management Co.,Ltd. 0.06% Reduce -13.6% 37,577 $10.3M
Illinois Municipal Retirement Fund 0.15% Add +1.3% 37,367 $10.3M
Bridger Management, LLC 5.09% No change 37,022 $10.2M
China Universal Asset Management Co., Ltd. 1.10% Add +37.1% 36,340 $10.0M
Arizona State Retirement System 0.06% Add +4.3% 36,240 $10.0M
Silverarc Capital Management, LLC 2.22% Reduce -0.6% 35,774 $9.8M
Rosenblum Silverman Sutton S F Inc. 2.47% Reduce -0.1% 35,155 $9.7M
Artia Global Partners LP 2.72% No change 35,000 $9.6M
Teachers Retirement System of the State of Kentucky 0.08% Add +4.5% 34,713 $9.5M
Acadian Asset Management LLC 0.03% Reduce -7.8% 34,417 $9.5M
Teacher Retirement System of Texas 0.04% Add +14.6% 33,650 $9.3M
Balyasny Asset Management L.P. 0.02% New 33,405 $9.2M
USS Investment Management Ltd 0.07% Reduce -10.8% 32,871 $9.0M
Driehaus Capital Management LLC 0.08% Reduce -0.4% 32,350 $8.9M
Tobam 1.58% Add +5.8% 31,467 $8.7M
Envestnet Asset Management Inc. 0.00% Add +24.8% 31,367 $8.6M
Atika Capital Management LLC 0.91% Add +26.5% 31,000 $8.5M
STRS Ohio 0.03% Add +17.9% 29,468 $8.1M
AIA Group Ltd 0.20% Add +45.2% 28,217 $7.8M
Schonfeld Strategic Advisors LLC 0.06% Reduce -36.6% 27,867 $7.7M
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund 0.08% — 27,815 $7.7M
Allianz Asset Management GmbH 0.01% Add +47.5% 26,806 $7.4M
Parallax Volatility Advisers, L.P. 0.22% New 26,535 $7.3M
AQR Arbitrage LLC 0.30% New 26,430 $7.3M
IFM Investors Pty Ltd 0.07% Add +0.6% 25,919 $7.1M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.02% Reduce -17.5% 25,812 $7.1M
Parkman Healthcare Partners LLC 0.89% New 25,485 $7.0M
DNB Asset Management AS 0.03% Reduce -2.4% 25,398 $7.0M
Caisse de depot et placement du Quebec 0.01% No change 25,295 $7.0M
Integral Health Asset Management, LLC 0.81% New 25,000 $6.9M
KBC Group NV 0.02% Add +62.7% 24,566 $6.8M
Aviva PLC 0.02% Add +125.0% 24,506 $6.7M
Citadel Advisors 0.01% Reduce -93.5% 23,932 $6.6M
Storebrand Asset Management As 0.02% Add +105.4% 23,183 $6.4M
Bank of Montreal 0.00% Reduce -30.1% 21,791 $6.0M
Banco Bilbao Vizcaya Argentaria, S.A. 0.06% New 21,741 $6.0M
Capital Group Investment Management Pte. LTD. 1.18% Add +9.1% 21,347 $5.9M
BRITISH COLUMBIA INVESTMENT MANAGEMENT Corp 0.03% Reduce -12.8% 21,108 $5.8M
Burney Co./ 0.20% Reduce -17.7% 20,947 $5.8M
Utah Retirement Systems 0.06% Add +1.0% 20,925 $5.8M
Xponance LLC 0.05% Reduce -2.0% 20,650 $5.7M
EFG Asset Management (North America) Corp. 0.95% Add +10.9% 20,615 $5.7M
Tidal Investments LLC 0.06% Add +75.1% 20,544 $5.7M
Aquatic Capital Management LLC 0.15% Add +537.8% 20,409 $5.6M
Lazard Asset Management LLC 0.01% Reduce -35.5% 19,879 $5.5M
Mackenzie Financial Corp. 0.01% Reduce -45.4% 19,691 $5.4M
Tredje AP-fonden 0.05% No change 19,483 $5.4M
Two Sigma Investments, LP 0.01% Reduce -81.4% 19,148 $5.3M
ExodusPoint Capital Management, LP 0.05% New 18,988 $5.2M
LPL Financial LLC 0.00% Add +0.9% 18,806 $5.2M
Federation des caisses Desjardins du Quebec 0.03% Add +17.7% 18,816 $5.2M
Hudson Bay Capital Management LP 0.04% Reduce -39.1% 18,262 $5.0M
NEOS Investment Management LLC 0.15% Add +3.0% 18,176 $5.0M
Nomura Holdings Inc. 0.04% Add +177.8% 17,849 $4.9M
Assenagon Asset Management S.A. 0.01% Reduce -85.6% 17,633 $4.8M
Gotham Asset Management 0.05% Add +32.8% 17,575 $4.8M
Verition Fund Management LLC 0.04% Add +135.6% 17,468 $4.8M
Groupama Asset Managment 0.12% Reduce -11.8% 21,385 $4.7M
Erste Asset Management GmbH 0.05% Reduce -42.1% 16,510 $4.5M
Silvant Capital Management LLC 0.20% Add +18.6% 16,195 $4.5M
Nissay Asset Management Corp. /Japan 0.03% Reduce -3.0% 15,623 $4.3M
Toronto Dominion Bank 0.01% Add +27.3% 15,466 $4.3M
Guggenheim Capital LLC 0.03% Reduce -20.5% 15,248 $4.2M
EFG Asset Management (Americas) Corp. 0.80% Reduce -12.0% 14,953 $4.1M
FIL Ltd 0.00% Reduce -2.6% 14,830 $4.1M
Montanova Capital, LLC 0.14% Reduce -63.3% 13,824 $3.8M
Public Employees Retirement Association of Colorado 0.01% No change 13,384 $3.7M
Blair William & Co. 0.01% New 13,334 $3.7M
Cerity Partners LLC 0.01% Add +133.6% 13,019 $3.6M
Andra AP-fonden 0.05% Add +309.7% 12,700 $3.5M
E Fund Management Co., Ltd. 0.18% Add +156.5% 12,637 $3.5M
PNC Financial Services Group, Inc. 0.00% Add +1.2% 12,543 $3.4M
Profund Advisors LLC 0.13% Reduce -16.2% 12,074 $3.3M
Daiwa Securities Group Inc. 0.02% Add +6.9% 12,072 $3.3M
Engineers Gate Manager LP 0.06% Add +67.7% 11,863 $3.3M
Mariner, LLC 0.01% Add +48.6% 11,719 $3.2M
Sumitomo Mitsui DS Asset Management Company, Ltd 0.03% Reduce -4.4% 11,581 $3.2M
Nisa Investment Advisors, LLC 0.02% Add +41.4% 11,528 $3.2M
J. Safra Sarasin Holding AG 0.05% Add +64.1% 11,274 $3.1M
Elo Mutual Pension Insurance Co 0.07% Reduce -1.8% 11,165 $3.1M
Raymond James & Associates 0.00% Reduce -32.7% 10,942 $3.0M
Raymond James Financial Services Advisors, Inc. 0.00% Add +390.9% 10,786 $3.0M
Cullen/Frost Bankers, Inc. 0.04% Add +0.8% 10,635 $2.9M
Principal Financial Group Inc. 0.00% Reduce -25.2% 10,608 $2.9M
Mirae Asset Global Investments Co., Ltd. 0.01% Reduce -20.9% 10,428 $2.9M
Mediolanum International Funds Ltd 0.04% New 10,198 $2.8M
Creative Planning 0.00% Add +24.6% 10,012 $2.8M
Natixis Advisors, LLC 0.01% New 10,002 $2.8M
Gulf International Bank (UK) Ltd 0.07% Reduce -4.6% 9,853 $2.7M
Algert Global LLC 0.07% Add +401.3% 9,825 $2.7M
Sectoral Asset Management Inc. 1.57% Reduce -22.4% 9,690 $2.7M
Nordea Investment Management AB 0.00% Add +1.2% 9,551 $2.6M
Assetmark, Inc. 0.01% Add +8.3% 9,186 $2.5M
Jupiter Asset Management Ltd. 0.02% New 9,147 $2.5M
Vanguard Personalized Indexing Management, LLC 0.04% Add +25.5% 8,978 $2.5M
Values First Advisors, Inc. 1.31% Add +15.8% 8,790 $2.4M
Ikarian Capital, LLC 0.75% New 8,741 $2.4M
M&T Bank Corp 0.01% Add +2.4% 8,645 $2.4M
BI Asset Management Fondsmaeglerselskab A/S 0.04% Add +86.8% 8,523 $2.3M
Portman Square Capital LLP 1.84% Reduce -28.1% 8,513 $2.3M
Caption Management, LLC 0.25% Reduce -95.1% 8,405 $2.3M
Employees Retirement System of Texas 0.02% Add +8.9% 8,403 $2.3M
Wealthfront Advisers LLC 0.01% Add +2.5% 8,296 $2.3M
Amalgamated Bank 0.02% Reduce -0.9% 8,279 $2.3M
Pinebridge Investments, L.P. 0.02% Reduce -7.7% 8,222 $2.3M
GTS Securities LLC 0.05% Add +648.5% 8,203 $2.3M
ProShare Advisors LLC 0.01% Reduce -2.9% 7,586 $2.1M
Nicholas Investment Partners, LP 0.21% New 7,526 $2.1M
CSS LLC 0.37% Add +971.4% 7,500 $2.1M
Savant Capital, LLC 0.02% New 7,447 $2.0M
Cibc World Markets Corp. 0.01% Add +8.1% 7,371 $2.0M
MetLife Investment Management, LLC 0.01% Reduce -1.9% 7,318 $2.0M
Vontobel Holding Ltd. 0.01% Reduce -13.7% 7,264 $2.0M
Traynor Capital Management, Inc. 0.16% New 7,249 $2.0M
Maryland State Retirement & Pension System 0.04% Reduce -26.9% 7,193 $2.0M
Intech Investment Management LLC 0.02% No change 7,145 $2.0M
Empowered Funds, LLC 0.03% Add +315.0% 7,064 $1.9M
Investment Management Corp of Ontario 0.04% Add +153.5% 7,059 $1.9M
Sphera Funds Management LTD. 0.32% New 7,000 $1.9M
Alberta Investment Management Corp 0.02% New 6,900 $1.9M
Cwm, LLC 0.01% Add +93.7% 6,764 $1.9M
Bank of Nova Scotia 0.00% Reduce -2.3% 6,483 $1.8M
Wealth Enhancement Advisory Services, LLC 0.00% Add +56.2% 6,454 $1.8M
Pathstone Holdings, LLC 0.01% Add +11.2% 6,249 $1.7M
Shell Asset Management Co. 0.07% — 6,197 $1.7M
Gateway Investment Advisers LLC 0.02% Reduce -7.7% 6,161 $1.7M
Polar Asset Management Partners Inc. 0.06% Reduce -41.0% 5,900 $1.6M
Stifel Financial Corp. 0.00% Reduce -1.8% 5,830 $1.6M
Advisory Services Network, LLC 0.03% No change 6,569 $1.6M
S&co Inc. 0.10% No change 5,750 $1.6M
Achmea Investment Management B.V. 0.03% Add +43.0% 5,742 $1.6M
Westpac Banking Corp. 0.11% Add +291.3% 5,741 $1.6M
Baader Bank Aktiengesellschaft 0.13% New 5,653 $1.6M
US Bancorp \de 0.00% Reduce -21.4% 5,578 $1.5M
Banque Cantonale Vaudoise 0.06% New 5,560 $1.5M
E. Ohman J:or Asset Management AB 0.04% New 5,400 $1.5M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Reduce -11.6% 5,371 $1.5M
Knollwood Investment Advisory, LLC 0.16% No change 5,355 $1.5M
Commonwealth Equity Services, LLC 0.00% Reduce -7.8% 5,303 $1.5M
New York State Teachers Retirement System 0.00% New 5,283 $1.5M
Lighthouse Investment Partners, LLC 0.07% New 5,000 $1.4M
Prelude Capital Management, LLC 0.10% Reduce -2.0% 4,833 $1.3M
Captrust Financial Advisors 0.00% Add +34.4% 4,833 $1.3M
Wbi Investments, LLC 0.32% New 4,804 $1.3M
Advisors Asset Management, Inc. 0.02% Add +4.1% 4,767 $1.3M
Plato Investment Management Ltd 0.10% Add +33.2% 4,702 $1.3M
Commerce Bank 0.01% Reduce -2.1% 4,522 $1.2M
Liontrust Investment Partners LLP 0.02% No change 5,083 $1.2M
CIBC Asset Management Inc 0.00% Add +5.5% 4,483 $1.2M
Ostrum Asset Management 0.10% Reduce -23.3% 4,403 $1.2M
Beacon Investment Advisory Services, Inc. 0.05% Reduce -5.1% 4,401 $1.2M
Choreo, LLC 0.02% Add +40.6% 4,370 $1.2M
Metis Global Partners, LLC 0.04% Add +47.2% 4,380 $1.2M
OMERS ADMINISTRATION Corp 0.01% No change 4,361 $1.2M
Brandywine Managers, LLC 1.29% No change 4,348 $1.2M
Ieq Capital, LLC 0.01% Add +37.9% 4,193 $1.2M
Perpetual Ltd 0.01% New 4,112 $1.1M
Sanctuary Advisors, LLC 0.01% Add +91.8% 4,558 $1.1M
J.P. Marvel Investment Advisors, LLC 0.18% No change 4,000 $1.1M
Howland Capital Management LLC 0.05% No change 4,000 $1.1M
First Hawaiian Bank 0.04% No change 4,000 $1.1M
Clearstead Trust, LLC 0.26% No change 3,981 $1.1M
Gilbert & Cook, Inc. 0.15% Reduce -3.4% 3,924 $1.1M
O'shaughnessy Asset Management, LLC 0.01% Add +275.5% 3,729 $1.1M
Walleye Capital LLC 0.01% Reduce -94.8% 3,649 $1.0M
AustralianSuper Pty Ltd 0.01% New 3,645 $1.0M
Swiss Life Asset Management Ltd 0.01% Add +85.7% 3,620 $995K
Graham Capital Management, L.P. 0.05% Add +45.6% 3,610 $993K
CI Investments Inc. 0.00% Reduce -0.7% 3,597 $989K
Exchange Traded Concepts, LLC 0.02% Add +4.0% 3,568 $981K
Aster Capital Management (DIFC) Ltd 0.21% — 3,558 $979K
Pallas Capital Advisors LLC 0.04% Add +61.8% 3,321 $975K
Orion Porfolio Solutions, LLC 0.01% Add +14.8% 3,541 $974K
Orion Portfolio Solutions, LLC 0.01% Add +14.8% 3,541 $974K
Sanders Morris Harris LLC 0.16% No change 3,500 $963K
PDT Partners, LLC 0.08% Reduce -75.6% 3,484 $958K
Orion Capital Management LLC 0.46% Reduce -4.2% 3,425 $942K
SG Americas Securities, LLC 0.00% Add +675.7% 3,390 $932K
Tudor Investment Corporation 0.01% Reduce -94.4% 3,386 $931K
Quantinno Capital Management LP 0.01% Add +50.3% 3,366 $926K
Spectrum Planning & Advisory Services Inc. 0.89% Reduce -5.7% 3,359 $924K
Souders Financial Advisors 0.13% Reduce -4.5% 3,353 $922K
B. Metzler seel. Sohn & Co. Holding AG 0.01% — 3,279 $902K
B. Metzler seel. Sohn & Co. AG 0.01% Reduce -18.4% 3,279 $902K
Hall Laurie J Trustee 0.28% No change 3,250 $894K
Diversified Trust Co. 0.02% Reduce -35.1% 3,230 $888K
Regal Investment Advisors LLC 0.06% Reduce -5.1% 3,177 $874K
Janney Montgomery Scott LLC 0.00% Reduce -0.2% 3,151 $867K
Atria Investments, Inc 0.01% Add +78.9% 3,145 $865K
Sequoia Financial Advisors, LLC 0.01% Reduce -5.4% 3,129 $861K
Old Mission Capital LLC 0.02% New 3,115 $857K
MML Investors Services, LLC 0.00% Add +5.7% 3,086 $849K
Prudential PLC 0.00% Add +5.0% 3,016 $829K
UniSuper Management Pty Ltd 0.01% No change 3,000 $825K
Fox Run Management, L.L.C. 0.18% New 2,885 $793K
Cetera Investment Advisers 0.00% Add +4.7% 2,868 $789K
Gsa Capital Partners LLP 0.06% Add +55.3% 2,860 $787K
Smith Group Asset Management, LLC 0.06% New 2,800 $770K
Horizon Kinetics Asset Management LLC 0.01% Reduce -4.2% 2,759 $759K
Semanteon Capital Management, LP 0.52% New 2,758 $759K
Shepherd Financial Partners LLC 0.09% New 2,736 $752K
GraniteShares Advisors LLC 0.51% Reduce -29.7% 2,719 $748K
Greenleaf Trust 0.01% Reduce -0.1% 2,718 $748K
Credit Agricole S A 0.00% Add +4.3% 2,683 $738K
Harbor Capital Advisors, Inc. 0.03% Add +0.3% 2,587 $712K
Sterling Capital Management LLC 0.01% — 2,580 $710K
Boothbay Fund Management, LLC 0.02% Reduce -24.5% 2,556 $703K
Kennedy Capital Management LLC 0.02% Add +13.8% 2,479 $682K
SteelPeak Wealth, LLC 0.03% Reduce -30.2% 2,475 $681K
Vestcor Inc 0.02% Add +20.6% 2,458 $676K
Lecap Asset Management Ltd. 0.14% New 2,433 $669K
Penserra Capital Management LLC 0.01% Reduce -77.7% 2,413 $663K
Integrated Wealth Concepts LLC 0.01% Add +0.9% 2,336 $642K
Rakuten Investment Management, Inc. 0.00% Add +33.1% 2,314 $636K
Corebridge Financial, Inc. 0.00% Reduce -3.5% 2,259 $621K
Nixon Peabody Trust Co. 0.05% Reduce -31.8% 2,250 $619K
New York Life Investment Management LLC 0.01% Reduce -1.4% 2,231 $614K
Bleakley Financial Group, LLC 0.02% Add +24.7% 2,215 $609K
Ethic Inc. 0.01% Add +12.7% 3,976 $594K
Monograph Wealth Advisors, LLC 0.08% No change 2,126 $585K
NorthCoast Asset Management LLC 0.00% New 2,431 $579K
Virtus Advisers, LLC 0.27% No change 2,058 $566K
State of Alaska, Department of Revenue 0.01% Reduce -52.5% 2,030 $558K
Bridgewater Associates 0.00% New 2,002 $551K
Security National Bank of So Dak 0.31% No change 2,000 $550K
Meiji Yasuda Asset Management Co Ltd. 0.02% Reduce -2.2% 1,986 $546K
Mutual of America Capital Management LLC 0.01% Add +26.7% 1,924 $529K
Comerica Bank 0.00% Reduce -84.8% 1,912 $526K
Loring Wolcott & Coolidge Fiduciary Advisors LLP 0.00% Reduce -6.0% 1,790 $526K
Oppenheimer & Co. Inc. 0.01% Add +11.1% 1,906 $524K
Unique Wealth Strategies, LLC 0.23% Add +8156.5% 1,899 $522K
First Trust Direct Indexing L.P. 0.03% Reduce -35.6% 1,895 $521K
Ellevest, Inc. 0.03% New 1,874 $515K
Truist Financial Corp. 0.00% Add +7.6% 1,859 $511K
Signaturefd, LLC 0.01% Add +34.1% 1,854 $510K
Motley Fool Asset Management LLC 0.03% Reduce -6.9% 1,760 $486K
Fort Sheridan Advisors LLC 0.07% No change 1,733 $477K
Everhart Financial Group, Inc. 0.10% Add +29.1% 1,706 $469K
Cresset Asset Management, LLC 0.00% Add +21.5% 1,675 $461K
Ossiam 0.01% Add +43.6% 1,675 $461K
Capstone Investment Advisors, LLC 0.02% New 1,653 $455K
Yousif Capital Management, LLC 0.00% Add +1.2% 1,633 $449K
Asahi Life Asset Management Co., LTD. 0.27% New 1,600 $440K
EntryPoint Capital, LLC 0.25% Add +56.4% 1,594 $438K
Emerald Advisers, LLC 0.02% Reduce -2.5% 1,577 $434K
United Capital Financial Advisors, LLC 0.00% Add +3.2% 1,568 $431K
HighVista Strategies LLC 0.15% Reduce -40.4% 1,551 $427K
JGP Global Gestao de Recursos Ltda. 0.83% Add +25.6% 1,548 $426K
Ballentine Partners, LLC 0.01% Add +10.4% 1,534 $422K
Convergence Investment Partners, LLC 0.11% New 1,513 $416K
High Net Worth Advisory Group LLC 0.12% No change 1,500 $413K
Forum Financial Management, LP 0.01% Add +0.1% 1,459 $401K
Wedmont Private Capital 0.02% Add +19.7% 1,477 $394K
Abn Amro Investment Solutions 0.01% New 1,394 $383K
Yarbrough Capital, LLC 0.02% New 1,376 $378K
Nichols & Pratt Advisers LLP 0.02% New 1,375 $378K
Beacon Pointe Advisors, LLC 0.00% Reduce -9.1% 1,375 $378K
Siemens Fonds Invest GmbH 0.03% New 1,365 $375K
Osaic Holdings, Inc. 0.00% Add +14.6% 1,364 $375K
Laird Norton Wetherby Wealth Management, LLC 0.02% Add +17.6% 1,351 $372K
North Star Asset Management Inc. 0.02% No change 1,310 $360K
Kestra Advisory Services, LLC 0.00% Reduce -6.3% 1,303 $358K
Cigna Investments Inc. 0.06% Reduce -1.9% 1,297 $357K
Brevan Howard Capital Management LP 0.02% New 1,289 $355K
Focus Partners Wealth 0.00% Reduce -14.1% 1,283 $353K
Inceptionr LLC 0.08% Reduce -77.3% 1,224 $337K
Grandfield & Dodd, LLC 0.02% New 1,224 $337K
Towarzystwo Funduszy Inwestycyjnych Pzu SA 0.12% Add +41.2% 1,200 $330K
Coldstream Capital Management Inc. 0.01% Add +43.6% 1,211 $329K
Envestnet Portfolio Solutions, Inc. 0.00% Add +3.8% 1,182 $325K
Freedom Investment Management, Inc. 0.03% Reduce -9.8% 1,159 $319K
Peregrine Capital Management LLC 0.01% No change 1,147 $315K
Summit Trail Advisors, LLC 0.01% Add +22.1% 1,134 $312K
American Trust 0.03% New 1,123 $309K
Clearstead Advisors, LLC 0.00% No change 1,110 $305K
Greenland Capital Management LP 0.06% New 1,104 $304K
Vident Advisory, LLC 0.01% Reduce -37.4% 1,095 $301K
Blueshift Asset Management, LLC 0.07% New 1,067 $293K
Fulton Bank, N.A. 0.01% Add +2.4% 1,042 $287K
Breakwater Capital Group 0.06% Add +0.5% 1,030 $283K
Axiom Advisory, LLC 0.00% New 1,088 $283K
Central Pacific Bank - Trust Division 0.04% Reduce -2.4% 1,025 $282K
OneDigital Investment Advisors LLC 0.00% New 1,021 $281K
Westmount Partners, LLC 0.08% Reduce -0.5% 1,000 $275K
Livforsakringsbolaget Skandia, Omsesidigt 0.01% Add +400.0% 1,000 $275K
Daiichi Life Insurance Co., Ltd. 0.01% Reduce -11.3% 955 $263K
SYM FINANCIAL Corp 0.03% Add +6.2% 947 $260K
Meeder Advisory Services, Inc. 0.02% New 933 $257K
HCR Wealth Advisors 0.03% No change 924 $254K
FUKOKU MUTUAL LIFE INSURANCE Co 0.02% No change 914 $251K
Crossmark Global Holdings, Inc. 0.00% Reduce -0.4% 914 $251K
Meridian Financial Advisors, LLC 0.17% No change 900 $248K
Steward Partners Investment Advisory, LLC 0.00% Add +1.1% 900 $248K
Nwam LLC 0.01% Add +0.5% 856 $235K
Ariadne Wealth Management, LP 0.13% New 855 $233K
Park Avenue Securities LLC 0.00% New 830 $228K
Chapin Davis, Inc. 0.07% No change 825 $227K
QRG Capital Management, Inc. 0.00% New 805 $221K
Quantitative Investment Management, LLC 0.02% Reduce -91.4% 802 $220K
Essex LLC 0.04% New 788 $217K
Allianz SE 0.01% New 760 $209K
Howard Capital Management, LLC 0.00% New 756 $208K
Sara-Bay Financial 0.07% New 750 $206K
Proficio Capital Partners LLC 0.02% Reduce -53.0% 744 $205K
JT Stratford LLC 0.03% New 737 $203K
EP Wealth Advisors, LLC 0.00% New 732 $201K
TrinityPoint Wealth, LLC 0.03% New 728 $200K
Plante Moran Financial Advisors, LLC 0.01% Reduce -42.3% 635 $175K
National Bank of Canada 0.00% Reduce -2.1% 613 $169K
Zions Bancorporation, N.A. 0.01% Add +2860.0% 592 $163K
PEAK6 Investments LLC 0.01% Reduce -77.9% 591 $163K
Wolverine Asset Management LLC 0.02% No change 590 $162K
Lindbrook Capital, LLC 0.01% Add +11.1% 570 $157K
Allworth Financial LP 0.00% Reduce -1.1% 559 $154K
GAMMA Investing LLC 0.02% Add +33.2% 554 $152K
Tower Research Capital LLC (TRC) 0.00% Reduce -44.4% 541 $149K
Parallel Advisors, LLC 0.00% Add +35.1% 539 $148K
Northwestern Mutual Wealth Management Co. 0.00% Reduce -12.3% 523 $144K
Arax Advisory Partners 0.01% Add +0.8% 485 $133K
Covestor Ltd 0.08% Reduce -41.1% 457 $126K
Prestige Wealth Management Group LLC 0.03% Add +65.8% 451 $124K
Smartleaf Asset Management LLC 0.01% Add +283.5% 441 $121K
Earned Wealth Advisors, LLC 0.04% New 440 $121K
Allspring Global Investments Holdings, LLC 0.00% Add +62.2% 420 $116K
Brooklyn Investment Group 0.04% New 413 $114K
Blue Trust, Inc. 0.00% Add +431.0% 462 $112K
Alta Advisers Ltd 0.05% No change 400 $110K
Spire Wealth Management 0.00% Add +0.8% 380 $105K
V-Square Quantitative Management LLC 0.01% Add +6.6% 356 $98K
EverSource Wealth Advisors, LLC 0.01% Add +8.4% 323 $89K
Itau Unibanco Holding S.A. 0.00% Reduce -5.8% 308 $85K
Quadrant Capital Group LLC 0.00% Add +9.1% 251 $69K
Farther Finance Advisors, LLC 0.00% Add +95.4% 211 $58K
Quantbot Technologies LP 0.00% Add +1754.5% 204 $56K
Concord Wealth Partners 0.01% No change 200 $55K
Anchor Investment Management, LLC 0.01% No change 200 $55K
CKW Financial Group 0.01% No change 200 $55K
IFP Advisors, Inc 0.00% Add +295.9% 194 $54K
Friedenthal Financial 0.03% New 184 $51K
Capital Advisors, Ltd. LLC 0.01% No change 162 $45K
Harvest Fund Management Co., Ltd 0.00% New 162 $45K
Carolinas Wealth Consulting LLC 0.01% New 159 $44K
True Wealth Design, LLC 0.02% Add +15300.0% 154 $42K
Washington Trust Advisors, Inc. 0.00% New 152 $42K
Coppell Advisory Solutions LLC 0.01% New 139 $38K
Harbour Investments, Inc. 0.00% Add +4.0% 131 $36K
Brown, Lisle/Cummings, Inc. 0.01% No change 125 $34K
Global Trust Asset Management, LLC 0.01% No change 122 $34K
Principal Securities, Inc. 0.00% Add +5.2% 121 $33K
Versant Capital Management, Inc 0.01% Add +72.6% 107 $29K
Sandy Spring Bank 0.00% No change 106 $29K
Hollencrest Capital Management 0.00% New 105 $29K
Global Retirement Partners, LLC 0.00% Add +90.6% 101 $28K
Hartford Financial Management Inc. 0.01% No change 100 $28K
Leonteq Securities AG 0.00% New 95 $26K
First Horizon Advisors, Inc. 0.00% Add +9.2% 95 $26K
Huntington National Bank 0.00% Add +91.8% 94 $26K
Cape Investment Advisory, Inc. 0.01% No change 90 $25K
TFC Financial Management, Inc. 0.00% Add +37.0% 74 $20K
Sachetta, LLC 0.01% Add +136.7% 71 $20K
MassMutual Private Wealth & Trust, FSB 0.00% Add +71.8% 67 $18K
Truvestments Capital LLC 0.00% New 57 $16K
Parkside Financial Bank & Trust 0.00% Add +36.6% 56 $15K
Bokf, NA 0.00% Reduce -99.0% 55 $15K
Brown Brothers Harriman & Co. 0.00% Add +92.6% 52 $14K
St. Johns Investment Management Company, LLC 0.01% No change 50 $14K
Princeton Global Asset Management LLC 0.00% No change 50 $14K
Piscataqua Savings Bank 0.01% Add +233.3% 50 $14K
Peoples Financial Services Corp. 0.01% No change 50 $14K
Geneos Wealth Management Inc. 0.00% New 47 $13K
Elequin Capital, LP 0.03% New 46 $13K
Centiva Capital, LP 0.00% Reduce -95.8% 42 $12K
MV Capital Management, Inc. 0.00% Add +53.9% 40 $11K
International Assets Investment Management, LLC 0.00% New 40 $11K
Larson Financial Group LLC 0.00% Add +44.4% 39 $11K
Bell Investment Advisors, Inc 0.00% Add +5.7% 37 $10K
Meeder Asset Management Inc. 0.00% Reduce -88.5% 37 $10K
Whittier Trust Co. 0.00% No change 36 $10K
Hemington Wealth Management 0.00% New 36 $9K
Bessemer Group Inc. 0.00% New 33 $9K
Bogart Wealth, LLC 0.00% Reduce -13.9% 31 $9K
TD Waterhouse Canada Inc. 0.00% Reduce -96.4% 30 $8K
JFS Wealth Advisors, LLC 0.00% Add +14.3% 24 $7K
Cornerstone Planning Group LLC 0.00% Add +76.9% 23 $7K
Ascentis Independent Advisors 0.00% New 23 $6K
Fifth Third Bancorp 0.00% Add +340.0% 22 $6K
Avion Wealth 0.00% Add +40.0% 21 $5K
Cetera Trust Company, N.A 0.00% No change 16 $4K
Quent Capital, LLC 0.00% No change 16 $4K
FinTrust Capital Advisors, LLC 0.00% No change 15 $4K
Sunbelt Securities, Inc. 0.00% No change 15 $4K
WFA Asset Management Corp 0.00% No change 14 $4K
Fortitude Family Office, LLC 0.00% New 14 $4K
Front Row Advisors LLC 0.00% No change 14 $4K
Trust Co. of Vermont 0.00% New 14 $4K
Semmax Financial Advisors Inc. 0.00% No change 14 $4K
Raffa Wealth Management, LLC 0.00% No change 13 $4K
DT Investment Partners, LLC 0.00% New 11 $3K
Rakuten Securities, Inc. 0.00% Reduce -83.1% 11 $3K
AdvisorNet Financial, Inc 0.00% Add +10.0% 11 $3K
Mark Sheptoff Financial Planning, LLC 0.00% No change 10 $3K
Richardson Financial Services Inc. 0.00% Add +100.0% 10 $3K
Wilmington Savings Fund Society, FSB 0.00% New 9 $2K
Private Wealth Management Group, LLC 0.00% No change 8 $2K
FSA Wealth Management LLC 0.00% — 8 $2K
DiNuzzo Private Wealth, Inc. 0.00% No change 7 $2K
Clear Investment Research, LLC 0.00% New 7 $2K
J.Safra Asset Management Corp 0.00% New 7 $2K
Criterion Capital Advisors, LLC 0.00% No change 7 $2K
CVA Family Office, LLC 0.00% New 6 $2K
Continuum Advisory, LLC 0.00% New 6 $2K
Mather Group, Llc. 0.00% Reduce -40.0% 6 $2K
SJS Investment Consulting Inc. 0.00% Add +25.0% 5 $1K
Avior Wealth Management, LLC 0.00% Reduce -44.4% 5 $1K
Montag A & Associates Inc. 0.00% No change 5 $1K
JNBA Financial Advisors 0.00% No change 4 $1K
Venturi Wealth Management, LLC 0.00% New 4 $1K
WR Wealth Planners, LLC 0.00% New 4 $1K
Winthrop Capital Management, LLC 0.00% Reduce -16.7% 5 $1K
Capital Analysts, LLC 0.00% New 2 $1K
Abound Wealth Management 0.00% New 3 $826
Voisard Asset Management Group, Inc. 0.00% New 3 $826
Riverview Trust Co 0.00% New 3 $825
Private Trust Co. NA 0.00% New 3 $825
Pacific Capital Wealth Advisors, Inc. 0.00% New 3 $825
Concourse Financial Group Securities, Inc. 0.00% Reduce -86.4% 3 $825
Addison Advisors LLC 0.00% New 2 $551
Manchester Capital Management LLC 0.00% No change 2 $551
CoreCap Advisors, LLC 0.00% No change 2 $550
First Personal Financial Services 0.00% New 1 $276
Salem Investment Counselors Inc. 0.00% New 1 $276
NewEdge Advisors, LLC 0.00% Reduce -99.9% 1 $275
Summit Securities Group LLC 0.00% New 1 $0

"% of holder's portfolio" is ALNY's weight in each manager's 13F, not the share of Alnylam Pharmaceuticals Inc. the manager owns.