Protagonist TherapeuticsPTGX
13F holders, Q3 2025 (September 30)275holders +2
39new positions
39sold out
5famous investors
$66.43avg. 13F price*
At the end of Q3 2025, 275 institutions reported holding Protagonist Therapeutics Inc. (PTGX) in their 13F filings, up 2 from Q2 2025. 39 opened new positions and 39 sold out. The largest holders were BlackRock, Inc. ($624.7M), Farallon Capital Management, L.L.C. ($411.6M) and RTW Investments, LP ($382.4M). 5 famous investors held it, including Stanley Druckenmiller (0.3% of Duquesne Family Office's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Protagonist Therapeutics Inc.
- CUSIP
- 74366E102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $160.4M |
| Exits | 39 | $115.4M |
All 13F filers, Q2 2025 → Q3 2025: 7,111,527 shares bought and 7,391,773 shares sold, net −280,246 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 275 holders
| BlackRock, Inc. | 0.01% | Reduce -2.4% | 9,404,232 | $624.7M |
| Farallon Capital Management, L.L.C. | 2.33% | Add +0.4% | 6,196,006 | $411.6M |
| RTW Investments, LP | 4.71% | No change | 5,756,277 | $382.4M |
| Vanguard Group Inc. | 0.00% | Reduce -2.3% | 4,257,229 | $282.8M |
| State Street Corp. | 0.01% | Reduce -1.3% | 3,165,795 | $210.3M |
| BVF Inc. | 6.90% | Reduce -20.3% | 2,560,916 | $170.1M |
| Johnson & Johnson | 32.29% | No change | 2,449,183 | $162.7M |
| Wellington Management Group LLP | 0.02% | Add +83.9% | 1,908,446 | $126.8M |
| UBS Group AG | 0.02% | Reduce -24.2% | 1,896,008 | $126.0M |
| Deep Track Capital, LP | 3.18% | Reduce -47.1% | 1,715,691 | $114.0M |
| Woodline Partners LP | 0.45% | Add +51.9% | 1,438,247 | $95.5M |
| Geode Capital Management, LLC | 0.01% | Reduce -1.9% | 1,416,646 | $94.1M |
| T. Rowe Price Associates Inc. | 0.01% | Add +30.3% | 1,220,436 | $81.1M |
| Driehaus Capital Management LLC | 0.54% | Add +50.4% | 1,139,854 | $75.7M |
| Janus Henderson Group PLC | 0.03% | Add +146.4% | 1,100,821 | $73.2M |
| Marshall Wace, LLP | 0.08% | New | 1,085,564 | $72.1M |
| Perceptive Advisors LLC | 2.01% | Reduce -4.1% | 1,030,134 | $68.4M |
| Commodore Capital LP | 3.32% | Reduce -4.7% | 1,025,000 | $68.1M |
| Invesco Ltd. | 0.01% | Add +39.1% | 1,003,706 | $66.7M |
| ADAR1 Capital Management, LLC | 6.55% | Add +4.3% | 989,182 | $65.7M |
| Bank of America Corp. | 0.00% | Reduce -2.6% | 829,877 | $55.1M |
| Pictet Asset Management Holding SA | 0.05% | Add +9.3% | 822,212 | $54.6M |
| Jefferies Financial Group Inc. | 0.52% | Reduce -0.3% | 821,503 | $54.6M |
| Goldman Sachs Group Inc. | 0.01% | Add +0.6% | 781,711 | $51.9M |
| Morgan Stanley | 0.00% | Reduce -11.6% | 768,359 | $51.0M |
| Adage Capital Partners Gp, L.L.C. | 0.08% | Reduce -34.3% | 718,202 | $47.7M |
| Lynx1 Capital Management LP | 9.47% | Reduce -4.5% | 700,014 | $46.5M |
| Northern Trust Corp. | 0.01% | Reduce -1.9% | 603,222 | $40.1M |
| American Century Companies Inc. | 0.02% | Reduce -26.3% | 600,047 | $39.9M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -3.9% | 552,877 | $36.7M |
| FMR LLC | 0.00% | Reduce -3.3% | 520,664 | $34.6M |
| Mangrove Partners Im, LLC | 2.64% | Add +21.0% | 478,413 | $31.8M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.08% | Add +1.3% | 451,766 | $30.0M |
| Focus Partners Wealth | 0.05% | New | 448,988 | $29.8M |
| Toronto Dominion Bank | 0.06% | No change | 445,440 | $29.6M |
| Dimensional Fund Advisors LP | 0.01% | Add +143.6% | 438,515 | $29.1M |
| 683 Capital Management, LLC | 2.58% | Reduce -8.4% | 407,500 | $27.1M |
| Bank of New York Mellon Corp | 0.00% | Reduce -6.4% | 363,261 | $24.1M |
| Principal Financial Group Inc. | 0.01% | Reduce -1.2% | 326,088 | $21.7M |
| Voya Investment Management LLC | 0.02% | Add +8.9% | 305,419 | $20.3M |
| Logos Global Management LP | 1.97% | New | 300,000 | $19.9M |
| Raymond James Financial Inc. | 0.01% | Reduce -5.7% | 294,296 | $19.6M |
| Alliancebernstein L.P. | 0.01% | Add +284.2% | 260,854 | $17.3M |
| JPMorgan Chase & Co. | 0.00% | Reduce -43.4% | 252,400 | $16.8M |
| Citadel Advisors | 0.01% | Add +774.5% | 237,881 | $15.8M |
| Public Sector Pension Investment Board | 0.06% | Add +8.0% | 228,146 | $15.2M |
| Affinity Asset Advisors, LLC | 1.41% | Reduce -49.9% | 220,600 | $14.7M |
| Kennedy Capital Management LLC | 0.31% | Add +54.5% | 208,437 | $13.8M |
| Barclays PLC | 0.00% | Reduce -19.2% | 171,406 | $11.4M |
| Rhumbline Advisers | 0.01% | Reduce -5.2% | 163,980 | $10.9M |
| Duquesne Family Office | 0.27% | New | 159,700 | $10.6M |
| Legal & General Group Plc | 0.00% | Reduce -6.2% | 155,829 | $10.4M |
| Ameriprise Financial Inc. | 0.00% | Reduce -9.0% | 153,191 | $10.2M |
| Citigroup Inc. | 0.01% | Add +95.7% | 152,580 | $10.1M |
| TD Asset Management Inc | 0.01% | Add +29.3% | 150,428 | $10.0M |
| Panagora Asset Management Inc. | 0.04% | Reduce -0.0% | 148,729 | $9.9M |
| Nan Fung Trinity (hk) Ltd. | 0.96% | Add +7.3% | 144,892 | $9.6M |
| Moody Aldrich Partners LLC | 1.80% | Reduce -16.1% | 143,060 | $9.5M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +42.5% | 135,096 | $9.0M |
| Nuveen, LLC | 0.00% | Reduce -0.9% | 128,384 | $8.5M |
| Millennium Management | 0.01% | Add +739.7% | 127,560 | $8.5M |
| Prudential Financial Inc. | 0.01% | Add +63.3% | 126,403 | $8.4M |
| ExodusPoint Capital Management, LP | 0.12% | New | 124,929 | $8.3M |
| Neuberger Berman Group LLC | 0.01% | Add +31.8% | 123,377 | $8.2M |
| Segall Bryant & Hamill, LLC | 0.11% | Add +2.5% | 123,125 | $8.2M |
| HighVista Strategies LLC | 1.98% | Add +110.3% | 121,682 | $8.1M |
| Deutsche Bank AG | 0.00% | Add +5.4% | 117,212 | $7.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -54.7% | 110,229 | $7.3M |
| Boxer Capital Management, LLC | 2.33% | Add +83.3% | 110,000 | $7.3M |
| Opaleye Management Inc. | 0.99% | No change | 105,000 | $7.0M |
| Swiss National Bank | 0.00% | Add +2.5% | 96,100 | $6.4M |
| Schonfeld Strategic Advisors LLC | 0.04% | Add +23.5% | 95,190 | $6.3M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +123.1% | 90,317 | $6.0M |
| Great Lakes Advisors, LLC | 0.05% | Reduce -36.0% | 89,171 | $5.9M |
| Victory Capital Management Inc. | 0.00% | Reduce -6.0% | 85,494 | $5.7M |
| Knott David M Jr | 2.31% | Add +3.8% | 83,000 | $5.5M |
| Atika Capital Management LLC | 0.47% | New | 83,000 | $5.5M |
| Franklin Resources Inc. | 0.00% | Add +0.4% | 82,918 | $5.5M |
| EFG Asset Management (North America) Corp. | 0.71% | Add +1.1% | 82,639 | $5.5M |
| Axiom Investors LLC | 0.04% | Add +56.4% | 80,113 | $5.3M |
| Skandinaviska Enskilda Banken AB (publ) | 0.02% | Reduce -4.8% | 78,796 | $5.2M |
| Informed Momentum Co LLC | 0.60% | Add +11.3% | 80,067 | $5.2M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -7.1% | 74,827 | $5.0M |
| Royal Bank of Canada | 0.00% | Reduce -6.3% | 69,996 | $4.7M |
| Assenagon Asset Management S.A. | 0.01% | Reduce -28.4% | 65,756 | $4.4M |
| Susquehanna International Group, LLP | 0.01% | Reduce -11.3% | 63,188 | $4.2M |
| First Trust Advisors LP | 0.00% | Reduce -44.9% | 62,724 | $4.2M |
| Parkman Healthcare Partners LLC | 0.45% | Add +0.4% | 61,849 | $4.1M |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -25.4% | 58,894 | $3.9M |
| Silvercrest Asset Management Group LLC | 0.02% | Reduce -2.8% | 53,217 | $3.5M |
| Diadema Partners LP | 2.37% | Reduce -32.8% | 51,185 | $3.4M |
| New York State Teachers Retirement System | 0.01% | Reduce -11.1% | 49,550 | $3.3M |
| Birchview Capital, LP | 2.41% | No change | 48,000 | $3.2M |
| Stempoint Capital LP | 0.64% | Add +185.9% | 47,954 | $3.2M |
| Wells Fargo & Company | 0.00% | Add +14.7% | 47,794 | $3.2M |
| California State Teachers Retirement System | 0.00% | Reduce -7.3% | 47,437 | $3.2M |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -3.6% | 48,407 | $3.2M |
| Jane Street Group, LLC | 0.00% | New | 44,339 | $2.9M |
| Sei Investments Co. | 0.00% | Reduce -2.0% | 44,011 | $2.9M |
| Thrivent Financial for Lutherans | 0.01% | Reduce -7.4% | 42,188 | $2.8M |
| SG Americas Securities, LLC | 0.01% | Add +2043.8% | 41,246 | $2.7M |
| State of Wisconsin Investment Board | 0.01% | Add +24.0% | 40,906 | $2.7M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -7.5% | 37,956 | $2.5M |
| Creative Planning | 0.00% | Add +19.9% | 36,214 | $2.4M |
| MetLife Investment Management, LLC | 0.01% | Reduce -2.7% | 33,846 | $2.2M |
| Exchange Traded Concepts, LLC | 0.02% | Reduce -29.2% | 33,552 | $2.2M |
| Illinois Municipal Retirement Fund | 0.03% | Add +20.4% | 33,183 | $2.2M |
| SummitTX Capital, L.P. | 0.09% | New | 31,490 | $2.1M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -13.9% | 30,871 | $2.0M |
| State of Alaska, Department of Revenue | 0.02% | Reduce -20.3% | 29,425 | $2.0M |
| Alps Advisors Inc. | 0.01% | Reduce -27.4% | 29,203 | $1.9M |
| Louisiana State Employees Retirement System | 0.03% | Reduce -7.2% | 26,900 | $1.8M |
| State of Tennessee, Department of Treasury | 0.01% | Add +1.9% | 26,490 | $1.8M |
| Envestnet Asset Management Inc. | 0.00% | Add +1.6% | 24,258 | $1.6M |
| Artia Global Partners LP | 0.27% | No change | 22,951 | $1.5M |
| Gotham Asset Management | 0.01% | Reduce -40.5% | 22,198 | $1.5M |
| Intech Investment Management LLC | 0.01% | Reduce -36.3% | 21,643 | $1.4M |
| Hussman Strategic Advisors, Inc. | 0.30% | Reduce -33.3% | 21,000 | $1.4M |
| Bellevue Group AG | 0.03% | Add +5.7% | 20,581 | $1.4M |
| Superstring Capital Management LP | 1.33% | New | 20,358 | $1.4M |
| Capital Fund Management S.A. | 0.01% | Reduce -59.1% | 20,348 | $1.4M |
| Polen Capital Management LLC | 0.00% | Add +27.0% | 20,325 | $1.4M |
| Allianz Asset Management GmbH | 0.00% | Reduce -11.8% | 19,678 | $1.3M |
| New York State Common Retirement Fund | 0.00% | No change | 19,582 | $1.3M |
| Handelsbanken Fonder AB | 0.00% | Add +11.2% | 18,900 | $1.3M |
| Guggenheim Capital LLC | 0.01% | Reduce -3.3% | 18,583 | $1.2M |
| WINTON GROUP Ltd | 0.05% | Add +6.5% | 18,561 | $1.2M |
| Yousif Capital Management, LLC | 0.01% | Reduce -21.3% | 18,426 | $1.2M |
| Profund Advisors LLC | 0.04% | Reduce -4.8% | 18,157 | $1.2M |
| J. Goldman & Co LP | 0.05% | Reduce -49.6% | 18,068 | $1.2M |
| Glenmede Investment Management, LP | 0.01% | Reduce -16.0% | 18,000 | $1.2M |
| STRS Ohio | 0.00% | Reduce -9.2% | 17,800 | $1.2M |
| Teachers Retirement System of the State of Kentucky | 0.01% | Reduce -7.7% | 17,296 | $1.1M |
| Royce & Associates LP | 0.01% | Add +38.6% | 16,989 | $1.1M |
| Natixis Advisors, LLC | 0.00% | Add +25.4% | 16,855 | $1.1M |
| Amalgamated Bank | 0.01% | Reduce -4.1% | 16,826 | $1.1M |
| Comerica Bank | 0.00% | Reduce -23.0% | 16,395 | $1.1M |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 16,303 | $1.1M |
| Moran Wealth Management, LLC | 0.03% | Add +2.9% | 16,212 | $1.1M |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Add +19.8% | 16,119 | $1.1M |
| China Universal Asset Management Co., Ltd. | 0.09% | Reduce -15.9% | 15,905 | $1.1M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Reduce -17.9% | 15,600 | $1.0M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 15,800 | $1.0M |
| Commonwealth of Pennsylvania Public School Empls Retrmt SYS | 0.01% | Reduce -6.4% | 14,893 | $989K |
| Jain Global LLC | 0.01% | New | 14,850 | $986K |
| Arizona State Retirement System | 0.01% | Add +2.4% | 14,669 | $974K |
| Weiss Asset Management LP | 0.02% | New | 14,310 | $951K |
| Mariner, LLC | 0.00% | Reduce -13.7% | 13,551 | $900K |
| Pathstone Holdings, LLC | 0.00% | Add +63.0% | 13,362 | $888K |
| Erste Asset Management GmbH | 0.01% | No change | 13,500 | $879K |
| Oregon Public Employees Retirement Fund | 0.01% | Reduce -7.0% | 13,200 | $877K |
| ProShare Advisors LLC | 0.00% | Reduce -14.2% | 13,187 | $876K |
| BNP Paribas Financial Markets | 0.00% | Add +43.8% | 13,137 | $873K |
| Teacher Retirement System of Texas | 0.00% | Reduce -8.3% | 12,106 | $804K |
| Persistent Asset Partners Ltd | 0.57% | Reduce -32.8% | 11,780 | $783K |
| Franklin Street Advisors Inc. | 0.04% | No change | 11,300 | $751K |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -52.5% | 10,986 | $730K |
| Cambria Investment Management, L.P. | 0.04% | Add +25.0% | 10,944 | $727K |
| KLP Kapitalforvaltning As | 0.00% | No change | 10,400 | $691K |
| Cache Advisors, LLC | 0.12% | No change | 10,143 | $674K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 10,073 | $669K |
| HRT Financial LP | 0.00% | New | 9,470 | $629K |
| Tidal Investments LLC | 0.00% | Reduce -62.4% | 8,945 | $594K |
| Resona Asset Management Co.,Ltd. | 0.00% | New | 8,731 | $580K |
| Cerity Partners LLC | 0.00% | Reduce -11.4% | 8,618 | $572K |
| HighTower Advisors, LLC | 0.00% | Reduce -13.7% | 8,613 | $572K |
| AQR Capital Management | 0.00% | Reduce -50.8% | 8,570 | $569K |
| Maryland State Retirement & Pension System | 0.01% | Reduce -53.9% | 8,407 | $558K |
| Aviva PLC | 0.00% | Reduce -17.4% | 7,792 | $518K |
| Capstone Investment Advisors, LLC | 0.01% | Add +9.9% | 7,676 | $510K |
| Brevan Howard Capital Management LP | 0.01% | Reduce -71.8% | 7,598 | $505K |
| XTX Topco Ltd | 0.03% | Reduce -1.0% | 7,260 | $482K |
| New Vernon Capital Holdings II LLC | 0.22% | No change | 7,198 | $478K |
| Inspire Investing, LLC | 0.04% | Reduce -4.8% | 6,938 | $461K |
| Orion Porfolio Solutions, LLC | 0.00% | Add +5.0% | 6,928 | $460K |
| Mutual of America Capital Management LLC | 0.00% | Reduce -17.7% | 6,551 | $435K |
| CIBC Bancorp USA Inc. | 0.00% | — | 6,205 | $412K |
| King Wealth Management Group | 0.05% | No change | 6,000 | $399K |
| Public Employees Retirement Association of Colorado | 0.00% | New | 6,001 | $399K |
| Russell Investments Group, Ltd. | 0.00% | Add +4492.3% | 5,924 | $394K |
| Gsa Capital Partners LLP | 0.03% | New | 5,884 | $391K |
| US Bancorp \de | 0.00% | Add +12.0% | 5,852 | $389K |
| Advantage Alpha Capital Partners LP | 0.12% | Reduce -16.8% | 5,804 | $386K |
| Palumbo Wealth Management LLC | 0.11% | Reduce -30.0% | 5,268 | $350K |
| Kestra Advisory Services, LLC | 0.00% | Reduce -9.4% | 5,223 | $347K |
| Caprock Group, LLC | 0.01% | — | 5,802 | $343K |
| Vident Advisory, LLC | 0.00% | New | 5,070 | $337K |
| Burney Co./ | 0.01% | Reduce -19.9% | 5,064 | $336K |
| Vestcor Inc | 0.01% | New | 5,022 | $334K |
| LPL Financial LLC | 0.00% | Add +3.6% | 4,994 | $332K |
| Ameritas Investment Partners, Inc. | 0.01% | Reduce -17.7% | 4,863 | $323K |
| Advisors Asset Management, Inc. | 0.01% | Reduce -0.4% | 4,706 | $313K |
| Cornerstone Investment Partners, LLC | 0.01% | Reduce -7.0% | 4,632 | $308K |
| Certuity, LLC | 0.02% | New | 4,535 | $301K |
| Xponance LLC | 0.00% | Add +0.6% | 4,534 | $301K |
| Baader Bank Aktiengesellschaft | 0.02% | New | 4,300 | $286K |
| Bessemer Group Inc. | 0.00% | Add +748.2% | 4,275 | $283K |
| Mackenzie Financial Corp. | 0.00% | Reduce -81.9% | 4,064 | $270K |
| Quantinno Capital Management LP | 0.00% | New | 4,047 | $269K |
| Nisa Investment Advisors, LLC | 0.00% | Add +2.1% | 3,985 | $265K |
| Crossmark Global Holdings, Inc. | 0.00% | Reduce -2.4% | 3,966 | $263K |
| Bank of Montreal | 0.00% | Reduce -59.7% | 3,864 | $257K |
| Tower Research Capital LLC (TRC) | 0.01% | Reduce -28.8% | 3,801 | $253K |
| Velan Capital Investment Management LP | 0.23% | No change | 3,700 | $246K |
| FORA Capital, LLC | 0.04% | New | 3,685 | $245K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | New | 3,511 | $230K |
| Verdence Capital Advisors LLC | 0.01% | New | 3,038 | $229K |
| Captrust Financial Advisors | 0.00% | New | 3,312 | $220K |
| Quantbot Technologies LP | 0.01% | New | 3,303 | $219K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | New | 3,298 | $219K |
| iSAM Funds (UK) Ltd | 0.04% | New | 3,118 | $207K |
| Fox Run Management, L.L.C. | 0.03% | New | 3,103 | $206K |
| Rockefeller Capital Management L.P. | 0.00% | New | 2,980 | $198K |
| Lanark Financial, Inc. | 0.02% | Add +15.3% | 2,958 | $196K |
| PNC Financial Services Group, Inc. | 0.00% | Add +13.4% | 2,738 | $182K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.5% | 2,405 | $160K |
| Virtus Investment Advisers, LLC | 0.04% | Add +21.0% | 2,020 | $134K |
| GAMMA Investing LLC | 0.01% | Add +53.0% | 1,648 | $109K |
| AlphaQuest LLC | 0.01% | New | 1,618 | $107K |
| KBC Group NV | 0.00% | No change | 1,574 | $105K |
| Smartleaf Asset Management LLC | 0.01% | Add +11.6% | 1,403 | $91K |
| Osaic Holdings, Inc. | 0.00% | Add +17.4% | 1,391 | $91K |
| Quadrant Capital Group LLC | 0.00% | New | 1,352 | $90K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -12.3% | 1,338 | $89K |
| Covestor Ltd | 0.04% | Reduce -43.3% | 990 | $66K |
| Wexford Capital LP | 0.02% | Reduce -71.6% | 941 | $63K |
| Abich Financial Wealth Management LLC | 0.02% | — | 932 | $62K |
| Truvestments Capital LLC | 0.01% | Add +11.1% | 722 | $48K |
| Cwm, LLC | 0.00% | Reduce -8.7% | 556 | $37K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +138.9% | 540 | $36K |
| Salomon & Ludwin, LLC | 0.00% | New | 442 | $29K |
| Global Retirement Partners, LLC | 0.00% | No change | 316 | $21K |
| Fifth Third Bancorp | 0.00% | Add +45.5% | 307 | $20K |
| Hantz Financial Services, Inc. | 0.00% | Add +106.3% | 295 | $20K |
| Assetmark, Inc. | 0.00% | Reduce -3.5% | 280 | $19K |
| UMB Bank, n.a. | 0.00% | Add +29.6% | 258 | $17K |
| Allworth Financial LP | 0.00% | Add +111.1% | 247 | $16K |
| Rise Advisors, LLC | 0.01% | No change | 224 | $15K |
| Clearstead Advisors, LLC | 0.00% | Add +81.8% | 200 | $13K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -11.6% | 190 | $13K |
| Optiver Holding B.V. | 0.00% | New | 169 | $11K |
| Larson Financial Group LLC | 0.00% | Add +492.3% | 154 | $10K |
| Signaturefd, LLC | 0.00% | No change | 149 | $10K |
| Sterling Capital Management LLC | 0.00% | Reduce -1.4% | 141 | $9K |
| Farther Finance Advisors, LLC | 0.00% | Add +51.6% | 141 | $9K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 119 | $8K |
| Parallel Advisors, LLC | 0.00% | Add +5.2% | 102 | $7K |
| Danske Bank A/S | 0.00% | No change | 100 | $7K |
| Arax Advisory Partners | 0.00% | New | 92 | $6K |
| MAI Capital Management | 0.00% | No change | 86 | $6K |
| Rothschild Investment LLC | 0.00% | Reduce -22.7% | 85 | $6K |
| Aster Capital Management (DIFC) Ltd | 0.00% | New | 83 | $6K |
| Bell Investment Advisors, Inc | 0.00% | No change | 81 | $5K |
| Brown Brothers Harriman & Co. | 0.00% | No change | 81 | $5K |
| WPG Advisers, LLC | 0.00% | No change | 78 | $5K |
| Annis Gardner Whiting Capital Advisors, LLC | 0.00% | No change | 76 | $5K |
| Raffa Wealth Management, LLC | 0.00% | No change | 60 | $4K |
| Wealthspire Advisors, LLC | 0.00% | New | 48 | $3K |
| Parkside Financial Bank & Trust | 0.00% | No change | 45 | $3K |
| Huntington National Bank | 0.00% | No change | 39 | $3K |
| Wolff Wiese Magana LLC | 0.00% | No change | 35 | $2K |
| Farmers & Merchants Investments Inc. | 0.00% | No change | 35 | $2K |
| Bare Financial Services, Inc | 0.00% | Add +47.8% | 34 | $2K |
| Principal Securities, Inc. | 0.00% | Reduce -11.1% | 32 | $2K |
| Picton Mahoney Asset Management | 0.00% | No change | 25 | $2K |
| Marquette Asset Management, LLC | 0.00% | New | 28 | $2K |
| Versant Capital Management, Inc | 0.00% | Reduce -6.9% | 27 | $2K |
| Montag A & Associates Inc. | 0.00% | New | 25 | $2K |
| Clearstead Trust, LLC | 0.00% | No change | 21 | $1K |
| Jones Financial Companies LLLP | 0.00% | No change | 20 | $1K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 9 | $598 |
| Advisory Services Network, LLC | 0.00% | New | 9 | $598 |
| Abound Wealth Management | 0.00% | No change | 4 | $266 |
| Kilter Group LLC | 0.00% | No change | 4 | $266 |
| DecisionPoint Financial, LLC | 0.00% | No change | 4 | $256 |
"% of holder's portfolio" is PTGX's weight in each manager's 13F, not the share of Protagonist Therapeutics Inc. the manager owns.