InsmedINSM
13F holders, Q3 2024 (September 30)414holders +36
73new positions
37sold out
9famous investors
$73.03avg. 13F price*
At the end of Q3 2024, 414 institutions reported holding Insmed Inc. (INSM) in their 13F filings, up 36 from Q2 2024. 73 opened new positions and 37 sold out. The largest holders were Vanguard Group Inc. ($1.3B), BlackRock, Inc. ($1.1B) and T. Rowe Price Associates Inc. ($918.4M). 9 famous investors held it, including George Soros (1.0% of Soros Fund Management's portfolio), Steve Cohen (0.1% of Point72 Asset Management's portfolio) and Stanley Druckenmiller (0.1% of Duquesne Family Office's portfolio).
- Company
- Insmed Inc.
- CUSIP
- 457669307
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2024 → Q3 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 73 | $256.4M |
| Exits | 37 | $263.4M |
All 13F filers, Q2 2024 → Q3 2024: 28,916,627 shares bought and 16,557,690 shares sold, net +12,358,937 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 414 holders
| Vanguard Group Inc. | 0.02% | Add +7.1% | 17,143,177 | $1.3B |
| BlackRock, Inc. | 0.02% | — | 14,970,152 | $1.1B |
| T. Rowe Price Associates Inc. | 0.11% | Add +3.4% | 12,580,981 | $918.4M |
| Darwin Global Management, Ltd. | 62.31% | Add +196.4% | 10,497,277 | $766.3M |
| FMR LLC | 0.03% | Reduce -1.6% | 7,191,518 | $525.0M |
| Capital International Investors | 0.09% | Add +11.1% | 6,523,791 | $476.2M |
| State Street Corp. | 0.02% | Add +32.5% | 6,178,230 | $451.0M |
| Baker Bros. Advisors LP | 3.38% | Add +23.5% | 4,415,918 | $322.4M |
| Geode Capital Management, LLC | 0.02% | Add +4.7% | 3,813,384 | $278.4M |
| JPMorgan Chase & Co. | 0.02% | Add +13.0% | 3,306,346 | $241.4M |
| RTW Investments, LP | 3.46% | Reduce -10.1% | 3,272,008 | $238.9M |
| Artisan Partners Limited Partnership | 0.32% | Add +15.8% | 2,884,097 | $210.5M |
| Franklin Resources Inc. | 0.06% | Add +0.1% | 2,721,389 | $204.3M |
| Ameriprise Financial Inc. | 0.05% | Add +1.9% | 2,580,419 | $188.4M |
| Alliancebernstein L.P. | 0.06% | Reduce -1.7% | 2,450,093 | $178.9M |
| FIL Ltd | 0.16% | Add +60.7% | 2,439,748 | $178.1M |
| William Blair Investment Management, LLC | 0.44% | Reduce -30.2% | 2,420,908 | $176.7M |
| Macquarie Group Ltd. | 0.18% | Reduce -16.8% | 2,285,921 | $166.9M |
| T. Rowe Price Investment Management, Inc. | 0.10% | Reduce -6.5% | 2,277,143 | $166.2M |
| Palo Alto Investors LP | 18.40% | Reduce -9.3% | 1,940,993 | $141.7M |
| Principal Financial Group Inc. | 0.07% | Add +12.9% | 1,871,890 | $136.6M |
| Pictet Asset Management Holding SA | 0.15% | Add +25.0% | 1,863,341 | $135.9M |
| Clearbridge Investments, LLC | 0.10% | Add +10.0% | 1,808,767 | $132.0M |
| Norges Bank | 0.02% | Reduce -5.7% | 1,656,767 | $120.9M |
| Montanova Capital, LLC | 4.29% | Reduce -35.1% | 1,635,709 | $119.4M |
| Vestal Point Capital, LP | 9.22% | Add +113.3% | 1,600,000 | $116.8M |
| Janus Henderson Group PLC | 0.06% | Reduce -28.8% | 1,488,904 | $108.7M |
| Hood River Capital Management LLC | 1.74% | Add +11.9% | 1,472,555 | $107.5M |
| Lord, Abbett & Co. LLC | 0.35% | Add +152.5% | 1,470,961 | $107.4M |
| Bank of New York Mellon Corp | 0.02% | Reduce -18.6% | 1,470,217 | $107.3M |
| Northern Trust Corp. | 0.02% | Add +4.9% | 1,459,964 | $106.6M |
| Integral Health Asset Management, LLC | 12.46% | Reduce -6.5% | 1,450,000 | $105.8M |
| Charles Schwab Investment Management Inc. | 0.02% | Add +10.5% | 1,444,266 | $105.4M |
| Goldman Sachs Group Inc. | 0.02% | Add +17.1% | 1,393,049 | $101.7M |
| Morgan Stanley | 0.01% | Add +60.5% | 1,320,991 | $96.4M |
| Loomis Sayles & Co. L P | 0.12% | Reduce -1.4% | 1,210,187 | $88.3M |
| Bank of America Corp. | 0.01% | Add +3.1% | 1,153,898 | $84.2M |
| GW&K Investment Management, LLC | 0.72% | Add +51.4% | 1,153,515 | $84.2M |
| Eversept Partners, LP | 6.10% | Reduce -5.7% | 1,089,404 | $79.5M |
| Invesco Ltd. | 0.01% | Add +40.5% | 1,062,395 | $77.6M |
| Nuveen Asset Management, LLC | 0.02% | Reduce -20.2% | 1,061,157 | $77.5M |
| Adage Capital Partners Gp, L.L.C. | 0.13% | Reduce -22.1% | 1,032,562 | $75.4M |
| Wellington Management Group LLP | 0.01% | Add +2.6% | 962,459 | $70.3M |
| Eventide Asset Management, LLC | 1.14% | Add +34.2% | 906,395 | $66.2M |
| Assenagon Asset Management S.A. | 0.13% | Add +119.2% | 857,360 | $62.6M |
| Two Sigma Investments, LP | 0.14% | Add +643.6% | 801,139 | $58.5M |
| Marshall Wace, LLP | 0.07% | Reduce -38.3% | 771,211 | $56.3M |
| Jennison Associates LLC | 0.03% | Add +3.4% | 769,253 | $56.2M |
| Alyeska Investment Group, L.P. | 0.28% | Add +74.3% | 747,402 | $54.6M |
| Voya Investment Management LLC | 0.07% | Add +0.3% | 745,794 | $54.4M |
| Voloridge Investment Management, LLC | 0.20% | Reduce -19.9% | 738,951 | $53.9M |
| Novo Holdings A/S | 2.63% | Reduce -9.4% | 724,666 | $52.9M |
| American Century Companies Inc. | 0.03% | Reduce -4.2% | 723,683 | $52.8M |
| Emerald Advisers, LLC | 1.95% | Add +7.7% | 689,807 | $50.4M |
| First Light Asset Management, LLC | 4.18% | Add +25.0% | 688,910 | $50.3M |
| Rock Springs Capital Management LP | 1.63% | Reduce -15.5% | 683,344 | $49.9M |
| Polar Capital Holdings Plc | 0.24% | Add +166.7% | 680,000 | $49.6M |
| Jane Street Group, LLC | 0.08% | Reduce -21.5% | 659,675 | $48.2M |
| Long Focus Capital Management, LLC | 4.06% | Reduce -15.1% | 628,900 | $45.9M |
| Man Group plc | 0.13% | Add +1423.4% | 615,946 | $45.0M |
| MPM Bioimpact LLC | 6.74% | No change | 615,391 | $44.9M |
| Frontier Capital Management Co. LLC | 0.41% | Reduce -23.3% | 594,106 | $43.4M |
| Fiera Capital Corp | 0.13% | Reduce -2.2% | 592,415 | $43.2M |
| Avidity Partners Management LP | 2.20% | Add +37.7% | 592,000 | $43.2M |
| Summit Partners Public Asset Management, LLC | 1.90% | Add +113.0% | 578,356 | $42.2M |
| Millennium Management | 0.04% | Reduce -52.9% | 564,856 | $41.2M |
| Bellevue Group AG | 0.62% | Reduce -48.6% | 525,434 | $38.4M |
| Eagle Health Investments LP | 7.23% | No change | 513,700 | $37.5M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.09% | Reduce -22.1% | 509,439 | $37.2M |
| TD Asset Management Inc | 0.03% | Reduce -2.4% | 513,082 | $37.2M |
| Cormorant Asset Management, LP | 1.94% | Reduce -25.9% | 500,000 | $36.5M |
| Qube Research & Technologies Ltd | 0.07% | New | 489,307 | $35.7M |
| Emerald Mutual Fund Advisers Trust | 1.85% | Reduce -1.3% | 487,664 | $35.6M |
| Squarepoint Ops LLC | 0.12% | Add +860.7% | 485,618 | $35.5M |
| Ensign Peak Advisors, Inc | 0.06% | Add +34.8% | 484,121 | $35.3M |
| TimesSquare Capital Management, LLC | 0.53% | New | 483,869 | $35.3M |
| Soros Fund Management | 0.99% | Add +1.7% | 478,601 | $34.9M |
| Candriam S.C.A. | 0.20% | Reduce -14.3% | 476,494 | $34.8M |
| Victory Capital Management Inc. | 0.03% | Add +209.9% | 455,959 | $33.3M |
| Fred Alger Management, LLC | 0.16% | Reduce -9.3% | 452,316 | $33.0M |
| Octagon Capital Advisors LP | 5.11% | Reduce -32.8% | 436,820 | $31.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Reduce -3.3% | 422,936 | $30.9M |
| Kingdon Capital Management, L.L.C. | 4.29% | Reduce -36.0% | 400,000 | $29.2M |
| Two Sigma Advisers, LP | 0.07% | Add +32.9% | 392,700 | $28.7M |
| Allspring Global Investments Holdings, LLC | 0.04% | Add +18.9% | 390,134 | $28.5M |
| Dimensional Fund Advisors LP | 0.01% | Add +2937.9% | 367,252 | $26.8M |
| First Turn Management, LLC | 4.12% | Add +10.2% | 356,451 | $26.0M |
| Silverarc Capital Management, LLC | 5.72% | Add +148.3% | 347,695 | $25.4M |
| C WorldWide Group Holding A/S | 0.26% | No change | 343,110 | $25.0M |
| Citadel Advisors | 0.03% | Reduce -57.9% | 336,562 | $24.6M |
| Sei Investments Co. | 0.03% | Add +20.1% | 333,597 | $24.4M |
| Barclays PLC | 0.01% | Add +205.8% | 332,063 | $24.2M |
| BNP Paribas Financial Markets | 0.02% | Add +414.3% | 316,876 | $23.1M |
| Point72 Asset Management | 0.08% | Reduce -63.3% | 315,151 | $23.0M |
| UBS Group AG | 0.01% | Add +32.5% | 309,992 | $22.6M |
| Swiss National Bank | 0.01% | Add +9.0% | 302,500 | $22.1M |
| New York State Common Retirement Fund | 0.03% | Reduce -9.2% | 292,779 | $21.4M |
| Panagora Asset Management Inc. | 0.10% | Reduce -18.4% | 290,470 | $21.2M |
| Manufacturers Life Insurance Company, The | 0.02% | Add +1.8% | 288,073 | $21.0M |
| Sofinnova Investments, Inc. | 1.73% | Add +25.7% | 286,307 | $20.9M |
| First Trust Advisors LP | 0.02% | Add +406.4% | 280,819 | $20.5M |
| Deutsche Bank AG | 0.01% | Add +8.2% | 276,942 | $20.2M |
| Eagle Asset Management Inc. | 0.10% | Reduce -16.4% | 263,235 | $19.4M |
| Rhumbline Advisers | 0.02% | Add +11.2% | 263,045 | $19.2M |
| Susquehanna International Group, LLP | 0.03% | Add +73.2% | 261,546 | $19.1M |
| Bank of Montreal | 0.01% | New | 262,868 | $19.1M |
| California Public Employees Retirement System | 0.01% | Add +32.7% | 258,877 | $18.9M |
| Westfield Capital Management Co. LP | 0.08% | New | 251,739 | $18.4M |
| Envestnet Asset Management Inc. | 0.01% | Add +37.4% | 241,131 | $17.6M |
| Hudson Bay Capital Management LP | 0.14% | Reduce -48.7% | 240,000 | $17.5M |
| AXA S.A. | 0.05% | Add +0.0% | 227,181 | $16.6M |
| Rafferty Asset Management, LLC | 0.06% | Add +102.1% | 226,800 | $16.6M |
| Granahan Investment Management, LLC | 0.62% | Reduce -16.2% | 217,345 | $15.9M |
| Woodline Partners LP | 0.13% | Add +39.5% | 216,379 | $15.8M |
| Cutter Capital Management, LP | 4.65% | Reduce -5.2% | 215,884 | $15.8M |
| Readystate Asset Management LP | 1.95% | New | 211,789 | $15.5M |
| Samlyn Capital, LLC | 0.25% | Reduce -41.1% | 211,498 | $15.4M |
| Royal Bank of Canada | 0.00% | Add +6.0% | 200,436 | $14.6M |
| Ra Capital Management, L.P. | 0.17% | No change | 200,000 | $14.6M |
| Cubist Systematic Strategies, LLC | 0.21% | New | 191,229 | $14.0M |
| Iron Triangle Partners LP | 1.85% | Reduce -56.4% | 180,000 | $13.1M |
| Perceptive Advisors LLC | 0.28% | No change | 180,000 | $13.1M |
| Peregrine Capital Management LLC | 0.38% | Reduce -3.9% | 172,837 | $12.6M |
| Patient Square Capital LP | 4.65% | New | 171,704 | $12.5M |
| Group One Trading LLC | 0.49% | New | 170,710 | $12.5M |
| Driehaus Capital Management LLC | 0.10% | Add +60.9% | 167,430 | $12.2M |
| Legal & General Group Plc | 0.00% | Add +8.2% | 161,768 | $11.8M |
| Ikarian Capital, LLC | 3.51% | Add +223.7% | 154,835 | $11.3M |
| PFM Health Sciences, LP | 0.65% | Reduce -36.9% | 152,228 | $11.1M |
| Ally Bridge Group (NY) LLC | 5.89% | Add +16.9% | 150,833 | $11.0M |
| WCM Investment Management, LLC | 0.02% | Add +58.6% | 148,330 | $10.8M |
| California State Teachers Retirement System | 0.01% | Add +5.8% | 146,742 | $10.7M |
| Tri Locum Partners LP | 2.52% | Reduce -54.5% | 143,920 | $10.5M |
| Segall Bryant & Hamill, LLC | 0.14% | Reduce -3.9% | 140,915 | $10.3M |
| Schroder Investment Management Group | 0.01% | Reduce -28.7% | 140,422 | $10.2M |
| Prudential Financial Inc. | 0.01% | Add +139.9% | 134,590 | $9.8M |
| Parallax Volatility Advisers, L.P. | 0.29% | Reduce -27.6% | 132,558 | $9.7M |
| Altium Capital Management LLC | 2.83% | Reduce -31.6% | 130,000 | $9.5M |
| Rhenman & Partners Asset Management AB | 0.77% | Add +30.1% | 129,513 | $9.5M |
| Wells Fargo & Company | 0.00% | Reduce -39.0% | 127,495 | $9.3M |
| Van Eck Associates Corp. | 0.01% | New | 127,024 | $9.1M |
| Citigroup Inc. | 0.01% | Add +120.7% | 121,266 | $8.9M |
| Neuberger Berman Group LLC | 0.01% | Reduce -1.7% | 111,838 | $8.2M |
| Trexquant Investment LP | 0.10% | New | 111,682 | $8.2M |
| Aberdeen Group plc | 0.01% | No change | 111,612 | $8.1M |
| State of Wisconsin Investment Board | 0.02% | Add +5.9% | 109,325 | $8.0M |
| Informed Momentum Co LLC | 1.18% | Add +0.2% | 107,972 | $7.9M |
| Acuta Capital Partners, LLC | 6.36% | Add +49.1% | 107,500 | $7.8M |
| Allianz Asset Management GmbH | 0.01% | Reduce -8.3% | 105,677 | $7.7M |
| Nicholas Investment Partners, LP | 0.75% | Add +35.1% | 101,145 | $7.4M |
| Tang Capital Management LLC | 0.52% | No change | 100,000 | $7.3M |
| Caption Management, LLC | 0.78% | New | 98,800 | $7.2M |
| Nwi Management LP | 0.85% | New | 97,540 | $7.1M |
| Royce & Associates LP | 0.06% | No change | 95,027 | $6.9M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.02% | Add +17.6% | 94,961 | $6.9M |
| Global IMC LLC | 1.40% | Add +0.5% | 94,842 | $6.9M |
| Rice Hall James & Associates, LLC | 0.37% | Reduce -3.4% | 93,492 | $6.8M |
| MetLife Investment Management, LLC | 0.04% | Add +0.1% | 89,622 | $6.5M |
| Hennion & Walsh Asset Management, Inc. | 0.30% | Reduce -23.7% | 87,456 | $6.4M |
| Axiom Investors LLC | 0.06% | Reduce -30.6% | 87,214 | $6.4M |
| Russell Investments Group, Ltd. | 0.01% | Add +57.3% | 86,759 | $6.3M |
| ExodusPoint Capital Management, LP | 0.06% | Add +99.9% | 85,183 | $6.2M |
| Corebridge Financial, Inc. | 0.03% | Add +0.6% | 84,034 | $6.1M |
| HAP Trading, LLC | 3.09% | New | 83,481 | $6.1M |
| Algert Global LLC | 0.16% | Reduce -49.5% | 81,501 | $5.9M |
| CenterBook Partners LP | 0.36% | New | 81,336 | $5.9M |
| Engineers Gate Manager LP | 0.12% | New | 80,790 | $5.9M |
| Essex Investment Management Co. LLC | 0.98% | Reduce -25.2% | 77,193 | $5.6M |
| Mutual of America Capital Management LLC | 0.06% | Reduce -0.9% | 77,116 | $5.6M |
| Verition Fund Management LLC | 0.04% | Add +382.9% | 76,406 | $5.6M |
| Raymond James & Associates | 0.00% | Add +17.4% | 76,232 | $5.6M |
| Thornburg Investment Management Inc. | 0.07% | New | 75,869 | $5.5M |
| Ghost Tree Capital, LLC | 1.87% | Add +15.4% | 75,000 | $5.5M |
| D. E. Shaw & Co. | 0.01% | Reduce -76.9% | 66,735 | $4.9M |
| Walleye Capital LLC | 0.05% | Add +38.2% | 63,477 | $4.6M |
| AQR Capital Management | 0.01% | Add +3.9% | 62,880 | $4.6M |
| Comerica Bank | 0.02% | Add +15.5% | 62,094 | $4.5M |
| Atika Capital Management LLC | 0.48% | Add +72.2% | 62,000 | $4.5M |
| State of New Jersey Common Pension Fund D | 0.02% | Add +5.2% | 59,623 | $4.4M |
| Simplex Trading, LLC | 0.15% | New | 59,561 | $4.3M |
| Oak Ridge Investments LLC | 0.37% | Reduce -4.1% | 58,354 | $4.3M |
| Polar Asset Management Partners Inc. | 0.15% | Add +217.7% | 57,500 | $4.2M |
| Hillsdale Investment Management Inc. | 0.32% | Add +0.2% | 56,700 | $4.1M |
| FORA Capital, LLC | 0.48% | Reduce -20.0% | 55,580 | $4.1M |
| Artia Global Partners LP | 1.09% | Reduce -0.9% | 52,939 | $3.9M |
| Deerfield Management Company, L.P. | 0.06% | Add +365.4% | 52,861 | $3.9M |
| Lion Point Capital, LP | 15.29% | Reduce -25.8% | 52,200 | $3.8M |
| EFG Asset Management (North America) Corp. | 0.62% | Reduce -5.6% | 50,867 | $3.7M |
| Affinity Asset Advisors, LLC | 0.61% | Reduce -60.0% | 50,000 | $3.6M |
| DekaBank Deutsche Girozentrale | 0.01% | No change | 50,000 | $3.6M |
| Erste Asset Management GmbH | 0.04% | No change | 47,600 | $3.5M |
| Intech Investment Management LLC | 0.04% | New | 46,593 | $3.4M |
| Profund Advisors LLC | 0.13% | Add +100.6% | 46,186 | $3.4M |
| Picton Mahoney Asset Management | 0.13% | Reduce -38.3% | 45,543 | $3.3M |
| HighVista Strategies LLC | 1.14% | Reduce -64.2% | 45,447 | $3.3M |
| Creative Planning | 0.00% | Add +31.1% | 44,914 | $3.3M |
| Arizona State Retirement System | 0.02% | Add +13.0% | 44,620 | $3.3M |
| Boothbay Fund Management, LLC | 0.11% | Add +225.9% | 43,717 | $3.2M |
| Handelsbanken Fonder AB | 0.01% | Add +25.3% | 43,581 | $3.2M |
| Castleark Management LLC | 0.13% | Add +159.9% | 43,300 | $3.2M |
| Federated Hermes, Inc. | 0.01% | Add +327.1% | 42,983 | $3.1M |
| Treasurer of the State of North Carolina | 0.01% | New | 42,500 | $3.1M |
| Lighthouse Investment Partners, LLC | 0.17% | Add +20.0% | 42,000 | $3.1M |
| Baron Capital (BAMCO) | 0.01% | New | 40,500 | $3.0M |
| ProShare Advisors LLC | 0.01% | Add +32.2% | 39,850 | $2.9M |
| Schonfeld Strategic Advisors LLC | 0.02% | Reduce -48.9% | 39,832 | $2.9M |
| Teacher Retirement System of Texas | 0.01% | Add +25.4% | 38,866 | $2.8M |
| Campbell & CO Investment Adviser LLC | 0.21% | New | 38,649 | $2.8M |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -18.8% | 37,811 | $2.8M |
| State Board of Administration of Florida Retirement System | 0.01% | No change | 37,632 | $2.7M |
| Guggenheim Capital LLC | 0.02% | Add +2.2% | 37,305 | $2.7M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.01% | Add +7.3% | 36,721 | $2.7M |
| Legato Capital Management LLC | 0.33% | Reduce -19.9% | 36,079 | $2.6M |
| Pathstone Holdings, LLC | 0.01% | Add +9.4% | 35,544 | $2.6M |
| Parkman Healthcare Partners LLC | 0.33% | Reduce -55.9% | 35,433 | $2.6M |
| Stifel Financial Corp. | 0.00% | Reduce -5.5% | 33,854 | $2.5M |
| Exome Asset Management LLC | 1.66% | Reduce -40.9% | 33,600 | $2.5M |
| China Universal Asset Management Co., Ltd. | 0.27% | Add +74.5% | 33,052 | $2.4M |
| Wolverine Trading, LLC | 0.06% | Add +141.9% | 33,282 | $2.4M |
| Cinctive Capital Management LP | 0.13% | Reduce -78.9% | 30,706 | $2.2M |
| Soleus Capital Management, L.P. | 0.18% | Reduce -70.5% | 30,272 | $2.2M |
| ArrowMark Colorado Holdings LLC | 0.03% | No change | 30,000 | $2.2M |
| LPL Financial LLC | 0.00% | Add +5.9% | 29,585 | $2.2M |
| Truist Financial Corp. | 0.00% | Add +370.9% | 29,038 | $2.1M |
| Calamos Advisors LLC | 0.01% | Add +12.1% | 28,276 | $2.1M |
| Orion Porfolio Solutions, LLC | 0.02% | Add +48.5% | 28,087 | $2.1M |
| Orion Portfolio Solutions, LLC | 0.02% | Add +48.5% | 28,087 | $2.1M |
| Assetmark, Inc. | 0.01% | Add +12.9% | 26,053 | $1.9M |
| Mariner, LLC | 0.00% | Add +31.3% | 24,944 | $1.8M |
| Tidal Investments LLC | 0.02% | Add +447.0% | 24,102 | $1.8M |
| Compound Planning, Inc. | 0.11% | Add +1.4% | 23,248 | $1.7M |
| Qsemble Capital Management, LP | 0.31% | New | 23,155 | $1.7M |
| Aquatic Capital Management LLC | 0.04% | New | 23,000 | $1.7M |
| STRS Ohio | 0.01% | Add +3.1% | 23,000 | $1.7M |
| MML Investors Services, LLC | 0.01% | Add +36.2% | 22,201 | $1.6M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.04% | Add +54.0% | 21,819 | $1.6M |
| Dana Investment Advisors, Inc. | 0.05% | Reduce -6.0% | 21,596 | $1.6M |
| SG Americas Securities, LLC | 0.01% | Add +770.5% | 21,561 | $1.6M |
| Cerity Partners LLC | 0.00% | Add +513.6% | 21,348 | $1.6M |
| Skandinaviska Enskilda Banken AB (publ) | 0.01% | Add +17.8% | 21,084 | $1.5M |
| Natixis Advisors, LLC | 0.00% | New | 20,894 | $1.5M |
| Balyasny Asset Management L.P. | 0.00% | Reduce -87.0% | 20,815 | $1.5M |
| Duquesne Family Office | 0.05% | No change | 20,000 | $1.5M |
| Nebula Research & Development LLC | 0.16% | New | 18,636 | $1.4M |
| New York Life Investment Management LLC | 0.01% | New | 18,344 | $1.3M |
| Harbor Capital Advisors, Inc. | 0.06% | New | 17,682 | $1.3M |
| Ameritas Investment Partners, Inc. | 0.04% | Add +4.6% | 15,921 | $1.2M |
| Osaic Holdings, Inc. | 0.00% | Add +188.3% | 15,556 | $1.1M |
| Chartwell Investment Partners, LLC | 0.04% | Add +0.8% | 15,069 | $1.1M |
| E Fund Management Co., Ltd. | 0.05% | Add +113.5% | 14,551 | $1.1M |
| Oppenheimer Asset Management Inc. | 0.01% | Add +115.7% | 14,449 | $1.1M |
| Henshaw Capital LLC | 0.04% | Reduce -6.8% | 14,435 | $1.1M |
| Mirae Asset Securities (usa) Inc. | 0.06% | New | 13,942 | $1.0M |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 13,935 | $1.0M |
| Semanteon Capital Management, LP | 0.67% | Reduce -16.7% | 13,455 | $982K |
| HSBC Holdings PLC | 0.00% | Reduce -43.9% | 12,986 | $953K |
| Kennedy Capital Management LLC | 0.02% | Add +20.0% | 12,118 | $885K |
| Tudor Investment Corporation | 0.01% | New | 11,886 | $868K |
| Beacon Financial Advisory LLC | 0.29% | Reduce -15.6% | 11,675 | $852K |
| Susquehanna Portfolio Strategies, LLC | 0.06% | No change | 11,319 | $826K |
| J. Goldman & Co LP | 0.04% | New | 11,226 | $819K |
| Prelude Capital Management, LLC | 0.06% | Reduce -13.0% | 11,049 | $807K |
| Corient Private Wealth LP | 0.00% | Add +62.5% | 10,983 | $802K |
| Yorktown Management & Research Co Inc | 0.82% | No change | 10,970 | $801K |
| Shell Asset Management Co. | 0.03% | — | 10,567 | $771K |
| O'shaughnessy Asset Management, LLC | 0.01% | Add +237.4% | 10,237 | $769K |
| B. Metzler seel. Sohn & Co. Holding AG | 0.01% | — | 10,510 | $767K |
| B. Metzler seel. Sohn & Co. AG | 0.01% | New | 10,510 | $767K |
| Xponance LLC | 0.01% | Add +4.9% | 10,309 | $753K |
| Los Angeles Capital Management LLC | 0.00% | Add +164.8% | 10,179 | $743K |
| ClariVest Asset Management LLC | 0.08% | No change | 11,015 | $738K |
| MYDA Advisors LLC | 0.21% | New | 10,000 | $730K |
| Sectoral Asset Management Inc. | 0.42% | Reduce -1.4% | 9,681 | $707K |
| Mackenzie Financial Corp. | 0.00% | Add +13.3% | 9,670 | $706K |
| Knights of Columbus Asset Advisors LLC | 0.05% | Reduce -71.5% | 9,587 | $700K |
| Acadian Asset Management LLC | 0.00% | New | 9,482 | $692K |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 9,400 | $686K |
| Blair William & Co. | 0.00% | Reduce -29.3% | 9,091 | $664K |
| Cetera Investment Advisers | 0.00% | Add +22.1% | 8,833 | $645K |
| Keybank National Association | 0.00% | Add +0.1% | 8,781 | $641K |
| Caxton Associates LP | 0.03% | New | 8,269 | $604K |
| US Bancorp \de | 0.00% | Add +55.3% | 7,932 | $579K |
| Valence8 US LP | 0.25% | New | 7,865 | $574K |
| PNC Financial Services Group, Inc. | 0.00% | Add +42.0% | 7,550 | $551K |
| Avantax Advisory Services, Inc. | 0.00% | Add +22.7% | 7,481 | $546K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Add +33.6% | 7,142 | $521K |
| Catalyst Funds Management Pty Ltd | 0.11% | New | 7,000 | $511K |
| Commerce Bank | 0.00% | Add +2.4% | 6,833 | $499K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 6,800 | $496K |
| Saxon Interests, Inc. | 0.22% | Add +0.5% | 6,617 | $483K |
| Snowden Capital Advisors LLC | 0.01% | Add +6.9% | 6,444 | $470K |
| Tobam | 0.08% | New | 6,360 | $464K |
| Captrust Financial Advisors | 0.00% | Add +40.9% | 6,280 | $458K |
| QRG Capital Management, Inc. | 0.00% | Reduce -20.2% | 6,209 | $453K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +29.1% | 6,215 | $450K |
| JGP Global Gestao de Recursos Ltda. | 0.88% | New | 6,123 | $447K |
| Envestnet Portfolio Solutions, Inc. | 0.00% | Add +23.7% | 6,089 | $444K |
| Pitcairn Co. | 0.03% | Reduce -17.4% | 6,079 | $444K |
| Bridgefront Capital, LLC | 0.17% | Add +25.6% | 6,028 | $440K |
| HighMark Wealth Management LLC | 0.24% | Add +31.4% | 6,010 | $439K |
| Private Advisor Group, LLC | 0.00% | Reduce -34.0% | 5,659 | $413K |
| Park Avenue Securities LLC | 0.00% | Add +28.5% | 5,597 | $409K |
| EntryPoint Capital, LLC | 0.23% | Add +454.1% | 5,563 | $406K |
| Virtus Advisers, LLC | 0.18% | No change | 5,344 | $390K |
| Amalgamated Bank | 0.00% | No change | 5,327 | $389K |
| Vise Technologies, Inc. | 0.05% | Reduce -18.6% | 5,298 | $387K |
| Gsa Capital Partners LLP | 0.03% | New | 5,151 | $376K |
| AlphaCentric Advisors LLC | 0.27% | New | 5,000 | $365K |
| Blueshift Asset Management, LLC | 0.09% | New | 4,997 | $365K |
| Atria Investments, Inc | 0.00% | Add +61.7% | 4,985 | $364K |
| Values First Advisors, Inc. | 0.20% | New | 4,978 | $363K |
| Intrust Bank NA | 0.04% | Add +2.9% | 4,966 | $363K |
| &partners | 0.01% | Add +9.5% | 4,902 | $358K |
| CIBC Asset Management Inc | 0.00% | Add +3.5% | 4,438 | $324K |
| Fox Run Management, L.L.C. | 0.07% | New | 4,366 | $319K |
| KBC Group NV | 0.00% | Add +20.4% | 4,310 | $315K |
| RVW Wealth, LLC | 0.03% | No change | 4,239 | $309K |
| Cresset Asset Management, LLC | 0.00% | Add +28.6% | 4,118 | $301K |
| Aigen Investment Management, LP | 0.06% | New | 4,069 | $297K |
| CI Investments Inc. | 0.00% | New | 3,765 | $275K |
| ADAR1 Capital Management, LLC | 0.04% | Reduce -91.4% | 3,634 | $265K |
| Vident Advisory, LLC | 0.01% | New | 3,625 | $265K |
| Meeder Advisory Services, Inc. | 0.02% | Add +3.1% | 3,619 | $264K |
| Elevation Point Wealth Partners, LLC | 0.02% | New | 3,552 | $259K |
| Coldstream Capital Management Inc. | 0.01% | New | 3,490 | $255K |
| Sanctuary Advisors, LLC | 0.00% | New | 3,397 | $248K |
| Nisa Investment Advisors, LLC | 0.00% | Add +88.4% | 3,350 | $245K |
| Edgestream Partners, L.P. | 0.01% | Reduce -59.6% | 3,250 | $237K |
| Pinnacle Wealth Planning Services, Inc. | 0.03% | No change | 3,238 | $236K |
| Abel Hall, LLC | 0.15% | New | 3,182 | $232K |
| OneDigital Investment Advisors LLC | 0.00% | New | 3,181 | $232K |
| RWC Asset Management LLP | 0.02% | New | 3,084 | $225K |
| Ariston Services Group | 0.19% | No change | 3,000 | $219K |
| Farallon Capital Management, L.L.C. | 0.00% | Reduce -99.5% | 3,000 | $219K |
| M&T Bank Corp | 0.00% | New | 2,980 | $218K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Reduce -23.5% | 2,924 | $213K |
| Quarry LP | 0.06% | No change | 2,400 | $175K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -90.3% | 2,293 | $167K |
| Principal Securities, Inc. | 0.00% | Reduce -1.9% | 2,019 | $147K |
| Parallel Advisors, LLC | 0.00% | Add +2.1% | 1,914 | $140K |
| Danske Bank A/S | 0.00% | New | 1,900 | $139K |
| IFP Advisors, Inc | 0.00% | Add +1.0% | 1,840 | $134K |
| Quantbot Technologies LP | 0.01% | New | 1,827 | $133K |
| JCIC Asset Management Inc. | 0.05% | New | 1,820 | $133K |
| Blue Trust, Inc. | 0.00% | Add +2348.8% | 1,959 | $131K |
| State of Wyoming | 0.02% | Reduce -18.7% | 1,557 | $114K |
| National Bank of Canada | 0.00% | Reduce -23.9% | 1,521 | $111K |
| Pin Oak Investment Advisors Inc. | 0.10% | No change | 1,454 | $106K |
| Cwm, LLC | 0.00% | Reduce -7.6% | 1,450 | $106K |
| Walleye Trading LLC | 0.00% | Reduce -75.7% | 1,192 | $87K |
| Northwest & Ethical Investments L.P. | 0.00% | Reduce -34.4% | 1,050 | $77K |
| Lanark Financial, Inc. | 0.00% | No change | 771 | $56K |
| Exchange Traded Concepts, LLC | 0.00% | Add +522.5% | 747 | $55K |
| First Horizon Advisors, Inc. | 0.00% | Add +8.7% | 686 | $50K |
| Huntington National Bank | 0.00% | Reduce -5.0% | 632 | $46K |
| Daiwa Securities Group Inc. | 0.00% | Add +8.6% | 635 | $46K |
| Wolverine Asset Management LLC | 0.00% | No change | 597 | $44K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 593 | $43K |
| GAMMA Investing LLC | 0.00% | Add +71.3% | 538 | $39K |
| CIBC Private Wealth Group LLC | 0.00% | New | 506 | $37K |
| Montag A & Associates Inc. | 0.00% | Reduce -20.8% | 500 | $37K |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 500 | $37K |
| Jefferies Financial Group Inc. | 0.00% | Reduce -98.2% | 493 | $36K |
| Farther Finance Advisors, LLC | 0.00% | Add +2.8% | 478 | $35K |
| Clearstead Advisors, LLC | 0.00% | Add +218.8% | 475 | $35K |
| Groupama Asset Managment | 0.00% | New | 579 | $34K |
| AlphaQuest LLC | 0.00% | Reduce -62.6% | 459 | $34K |
| Signaturefd, LLC | 0.00% | Add +30.7% | 443 | $32K |
| Hexagon Capital Partners LLC | 0.01% | No change | 431 | $31K |
| Smartleaf Asset Management LLC | 0.00% | Add +22.9% | 419 | $30K |
| V-Square Quantitative Management LLC | 0.00% | New | 411 | $30K |
| Lindbrook Capital, LLC | 0.00% | Reduce -27.6% | 375 | $27K |
| Bessemer Group Inc. | 0.00% | Add +87.5% | 300 | $22K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +50.6% | 262 | $19K |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 250 | $18K |
| Private Trust Co. NA | 0.00% | Add +96.4% | 218 | $16K |
| UMB Bank, n.a. | 0.00% | Reduce -30.2% | 180 | $13K |
| Paloma Partners Management Co | 0.00% | Reduce -26.3% | 177 | $13K |
| Asset Dedication, LLC | 0.00% | New | 171 | $12K |
| Covestor Ltd | 0.01% | Reduce -72.1% | 163 | $12K |
| Sterling Capital Management LLC | 0.00% | — | 159 | $12K |
| Washington Trust Advisors, Inc. | 0.00% | No change | 149 | $11K |
| Rothschild Investment LLC | 0.00% | Add +262.5% | 145 | $11K |
| Versant Capital Management, Inc | 0.00% | No change | 108 | $8K |
| Wilmington Savings Fund Society, FSB | 0.00% | New | 96 | $7K |
| Trust Co. of Vermont | 0.00% | New | 95 | $7K |
| Johnson Financial Group, Inc. | 0.00% | New | 95 | $7K |
| Wolff Wiese Magana LLC | 0.00% | New | 94 | $7K |
| Global Retirement Partners, LLC | 0.00% | Add +29.2% | 93 | $7K |
| Truvestments Capital LLC | 0.00% | New | 84 | $6K |
| Allworth Financial LP | 0.00% | Add +30.2% | 69 | $5K |
| JFS Wealth Advisors, LLC | 0.00% | Add +41.7% | 68 | $5K |
| Cullen/Frost Bankers, Inc. | 0.00% | Add +106.3% | 66 | $5K |
| Cornerstone Planning Group LLC | 0.00% | No change | 61 | $4K |
| Bellevue Asset Management, LLC | 0.00% | No change | 57 | $4K |
| Meeder Asset Management Inc. | 0.00% | Add +17.0% | 55 | $4K |
| Northwestern Mutual Wealth Management Co. | 0.00% | New | 55 | $4K |
| Banque Cantonale Vaudoise | 0.00% | New | 55 | $4K |
| Hemington Wealth Management | 0.00% | New | 57 | $3K |
| Bell Investment Advisors, Inc | 0.00% | Add +35.0% | 27 | $2K |
| Arax Advisory Partners | 0.00% | Add +50.0% | 27 | $2K |
| Continuum Advisory, LLC | 0.00% | Add +92.9% | 27 | $2K |
| Earned Wealth Advisors, LLC | 0.00% | New | 23 | $2K |
| Park Place Capital Corp | 0.00% | No change | 23 | $2K |
| SJS Investment Consulting Inc. | 0.00% | Add +35.3% | 23 | $2K |
| DiNuzzo Private Wealth, Inc. | 0.00% | Add +40.0% | 21 | $2K |
| Evermay Wealth Management LLC | 0.00% | No change | 20 | $1K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +41.7% | 17 | $1K |
| Quadrant Capital Group LLC | 0.00% | No change | 15 | $1K |
| Valley National Advisers Inc. | 0.00% | Reduce -31.3% | 22 | $1K |
| Moisand Fitzgerald Tamayo, LLC | 0.00% | No change | 10 | $730 |
| Fortitude Family Office, LLC | 0.00% | New | 7 | $511 |
| Bokf, NA | 0.00% | No change | 7 | $500 |
| Riverview Trust Co | 0.00% | New | 6 | $438 |
"% of holder's portfolio" is INSM's weight in each manager's 13F, not the share of Insmed Inc. the manager owns.