Alnylam PharmaceuticalsALNY

13F holders, Q2 2024 (June 30)
523holders +25
83new positions
55sold out
6famous investors
$243.05avg. 13F price*

At the end of Q2 2024, 523 institutions reported holding Alnylam Pharmaceuticals Inc. (ALNY) in their 13F filings, up 25 from Q1 2024. 83 opened new positions and 55 sold out. The largest holders were Capital World Investors ($3.6B), Vanguard Group Inc. ($3.0B) and FMR LLC ($3.0B). 6 famous investors held it, including Paul Tudor Jones (0.2% of Tudor Investment Corporation's portfolio), David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio) and Cliff Asness (0.1% of AQR Capital Management's portfolio).

Company
Alnylam Pharmaceuticals Inc.
Sector
Health Care
CUSIP
02043Q107
Latest filing quarter
Q2 2026

History

Number of 13F holders

02004006008001,000 Q1 2024: 498Q1 2024Q2 2024: 523Q2 2024Q3 2024: 568Q3 2024Q4 2024: 594Q4 2024Q1 2025: 626Q1 2025Q2 2025: 654Q2 2025Q3 2025: 823Q3 2025Q4 2025: 852Q4 2025Q1 2026: 793Q1 2026Q2 2026: 793Q2 2026

Total Exit/New Position Q1 2024 → Q2 2024

InstitutionsTotal Value
New Positions83$504.9M
Exits55$251.6M

All 13F filers, Q1 2024 → Q2 2024: 12,115,610 shares bought and 6,928,435 shares sold, net +5,187,175 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 523 holders

Capital World Investors 0.59% Add +17.1% 14,971,343 $3.6B
Vanguard Group Inc. 0.06% Add +4.3% 12,507,778 $3.0B
FMR LLC 0.19% Add +22.0% 12,164,038 $3.0B
BlackRock Inc. 0.05% Add +5.8% 9,547,663 $2.3B
Wellington Management Group LLP 0.27% Reduce -13.8% 6,210,479 $1.5B
Baillie Gifford & Co. 1.14% Reduce -8.9% 6,032,656 $1.5B
Capital International Investors 0.19% Add +6.6% 3,891,059 $945.7M
Dodge & Cox 0.55% Reduce -0.8% 3,780,185 $918.6M
State Street Corp. 0.04% Add +10.8% 3,534,836 $859.0M
T. Rowe Price Associates Inc. 0.10% Reduce -5.4% 3,488,003 $847.6M
Capital Research Global Investors 0.17% Add +3.5% 3,255,648 $791.1M
T. Rowe Price Investment Management, Inc. 0.48% Add +9.8% 3,153,627 $766.3M
Norges Bank 0.08% Add +0.2% 2,296,781 $558.1M
Geode Capital Management, LLC 0.04% Add +3.9% 2,080,275 $504.6M
JPMorgan Chase & Co. 0.04% Add +1.4% 1,772,871 $430.8M
American Century Companies Inc. 0.20% Reduce -1.4% 1,354,169 $329.1M
Bellevue Group AG 3.63% Add +0.2% 919,834 $223.5M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.06% Add +10.1% 835,413 $203.0M
Northern Trust Corp. 0.03% Add +5.6% 780,835 $189.7M
Legal & General Group Plc 0.05% Add +1.5% 761,919 $185.1M
Pictet Asset Management Holding SA 0.21% Reduce -21.1% 758,528 $184.3M
Amundi 0.07% Reduce -1.2% 737,290 $183.3M
Morgan Stanley 0.01% Add +9.8% 741,514 $180.2M
Orbis Allan Gray Ltd 1.09% New 721,053 $175.2M
Bank of New York Mellon Corp 0.03% Reduce -15.6% 673,702 $163.7M
Bank of America Corp. 0.01% Add +30.1% 631,112 $153.4M
Nuveen Asset Management, LLC 0.04% Add +14.9% 588,469 $143.0M
Loomis Sayles & Co. L P 0.19% Reduce -2.2% 569,282 $138.3M
Goldman Sachs Group Inc. 0.02% Add +97.9% 514,667 $125.1M
Deep Track Capital, LP 3.63% Reduce -39.9% 500,000 $121.5M
TD Asset Management Inc 0.11% Add +6.0% 489,940 $119.1M
Deutsche Bank AG 0.05% Reduce -3.5% 489,118 $118.9M
Charles Schwab Investment Management Inc. 0.02% Add +5.2% 470,592 $114.4M
Royal Bank of Canada 0.02% Add +9.9% 411,364 $100.0M
Citigroup Inc. 0.09% Add +166.6% 401,660 $97.6M
Avoro Capital Advisors LLC 1.29% Add +33.3% 400,000 $97.2M
Gilder Gagnon Howe & Co. LLC 1.21% Reduce -1.6% 398,616 $96.9M
Invesco Ltd. 0.02% Add +120.3% 392,841 $95.5M
Swiss National Bank 0.06% Reduce -0.4% 374,400 $91.0M
Citadel Advisors 0.09% Add +818.6% 367,289 $89.3M
Candriam S.C.A. 0.52% Add +10.8% 351,228 $85.3M
Manufacturers Life Insurance Company, The 0.07% Reduce -2.4% 329,037 $80.0M
Franklin Resources Inc. 0.02% Add +21.8% 289,326 $70.3M
Polar Capital Holdings Plc 0.41% Add +21.3% 285,000 $69.3M
Canada Pension Plan Investment Board 0.07% Add +3.7% 283,933 $69.0M
Royal London Asset Management Ltd. 0.18% Reduce -13.6% 282,345 $68.6M
D. E. Shaw & Co. 0.10% Add +170.2% 279,398 $67.9M
Sumitomo Mitsui Trust Group, Inc. 0.05% Reduce -4.8% 276,947 $67.3M
Corient Private Wealth LP 0.12% Add +0.1% 274,736 $66.8M
AQR Capital Management 0.10% Add +92.5% 271,619 $65.9M
Mitsubishi UFJ Trust & Banking Corp 0.16% Reduce -13.9% 268,440 $65.2M
Dimensional Fund Advisors LP 0.02% Add +4.3% 266,206 $64.7M
Two Sigma Advisers, LP 0.14% Add +36.5% 258,700 $62.9M
Adage Capital Partners Gp, L.L.C. 0.11% New 254,000 $61.7M
Orbimed Advisors LLC 1.21% New 250,300 $60.8M
Rock Springs Capital Management LP 1.84% Add +2.5% 250,000 $60.8M
Janus Henderson Group PLC 0.03% Add +39.4% 249,440 $60.6M
Eagle Asset Management Inc. 0.32% Reduce -4.7% 246,204 $59.9M
ANTIPODES PARTNERS Ltd 2.16% Add +16.1% 238,749 $59.4M
First Trust Advisors LP 0.06% Add +10.7% 240,547 $58.5M
Ameriprise Financial Inc. 0.02% Add +22.4% 238,320 $57.9M
Avidity Partners Management LP 2.29% Reduce -8.6% 222,000 $53.9M
CIBC Private Wealth Group LLC 0.10% Add +18.4% 206,391 $52.7M
California Public Employees Retirement System 0.04% Add +0.6% 215,567 $52.4M
Wells Fargo & Company 0.01% Reduce -0.1% 206,148 $50.1M
Aberdeen Group plc 0.09% Reduce -8.8% 199,978 $48.6M
National Pension Service 0.05% Add +5.5% 196,387 $47.7M
California State Teachers Retirement System 0.06% Add +1.1% 193,594 $47.0M
Rhumbline Advisers 0.04% Reduce -0.2% 173,327 $42.1M
Caption Management, LLC 4.44% Add +49.5% 170,550 $41.4M
Casdin Capital, LLC 3.15% Reduce -52.5% 170,000 $41.3M
Frontier Capital Management Co. LLC 0.41% New 168,442 $40.9M
UBS Group AG 0.01% Add +25.8% 156,583 $38.0M
Sofinnova Investments, Inc. 2.27% Add +43.6% 147,929 $35.9M
Jane Street Group, LLC 0.04% Reduce -14.9% 139,497 $33.9M
Millennium Management 0.03% Reduce -31.5% 138,504 $33.7M
State Board of Administration of Florida Retirement System 0.06% Reduce -1.2% 135,347 $32.9M
Barclays PLC 0.01% Reduce -32.3% 131,265 $31.9M
Worldquant Millennium Advisors LLC 0.29% Add +115.7% 129,593 $31.5M
BNP Paribas Financial Markets 0.03% Add +24.2% 126,012 $30.6M
HighTower Advisors, LLC 0.05% Reduce -0.8% 125,041 $30.4M
Assenagon Asset Management S.A. 0.07% Add +103.5% 122,796 $29.8M
Deerfield Management Company, L.P. 0.56% New 119,800 $29.1M
Novo Holdings A/S 1.55% No change 118,383 $28.8M
Man Group plc 0.08% Reduce -43.9% 117,910 $28.7M
DekaBank Deutsche Girozentrale 0.05% Add +0.4% 113,463 $27.9M
Voya Investment Management LLC 0.03% Add +62.0% 114,234 $27.8M
Capital International, Inc. 0.37% Add +22.1% 113,984 $27.7M
Korea Investment CORP 0.07% Add +187.0% 112,383 $27.3M
AXA S.A. 0.08% Add +3.1% 110,975 $27.0M
Capital International Sarl 0.81% Add +50.2% 109,815 $26.7M
Skandinaviska Enskilda Banken AB (publ) 0.12% Add +13.1% 106,892 $26.0M
Two Sigma Investments, LP 0.06% Add +0.4% 102,918 $25.0M
Squarepoint Ops LLC 0.09% Reduce -83.0% 98,794 $24.0M
Neuberger Berman Group LLC 0.02% Add +4.4% 95,408 $23.2M
New York State Common Retirement Fund 0.03% Add +1.0% 94,685 $23.0M
Capital International Ltd. 1.06% Add +44.5% 94,225 $22.9M
Federated Hermes, Inc. 0.05% Reduce -37.6% 92,608 $22.5M
APG Asset Management N.V. 0.04% Add +38.8% 93,565 $21.2M
Eventide Asset Management, LLC 0.36% No change 87,000 $21.1M
Rhenman & Partners Asset Management AB 1.99% Add +102.1% 85,500 $20.8M
Rafferty Asset Management, LLC 0.07% Add +32.5% 81,110 $19.7M
Treasurer of the State of North Carolina 0.08% Reduce -8.9% 79,565 $19.3M
Nomura Asset Management Co. Ltd. 0.07% Reduce -0.6% 79,297 $19.3M
Mitsubishi UFJ Asset Management Co., Ltd. 0.02% Add +14.2% 78,561 $19.1M
State of Wisconsin Investment Board 0.05% Add +13.4% 77,936 $18.9M
Eagle Health Investments LP 3.31% Add +57.7% 76,256 $18.5M
Ensign Peak Advisors, Inc 0.03% Reduce -10.2% 73,473 $17.9M
Handelsbanken Fonder AB 0.08% Reduce -2.7% 73,051 $17.8M
Soleus Capital Management, L.P. 1.54% New 71,700 $17.4M
Walleye Capital LLC 0.20% Add +50.0% 70,307 $17.1M
Susquehanna International Group, LLP 0.03% Reduce -17.9% 67,011 $16.3M
Asset Management One Co., Ltd. 0.06% Reduce -3.3% 65,696 $16.0M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.05% Add +30.9% 65,485 $15.9M
U.S. Capital Wealth Advisors, LLC 0.57% No change 61,500 $14.9M
Van Eck Associates Corp. 0.02% Add +5.2% 60,938 $14.8M
Tudor Investment Corporation 0.16% New 60,393 $14.7M
Connor, Clark & Lunn Investment Management Ltd. 0.06% Add +287.9% 59,898 $14.6M
Macquarie Group Ltd. 0.02% Add +6.3% 59,455 $14.4M
Schroder Investment Management Group 0.02% Reduce -36.2% 56,724 $13.8M
Susquehanna Fundamental Investments, LLC 0.32% Reduce -35.8% 56,585 $13.8M
CANADA LIFE ASSURANCE Co 0.02% Add +14.4% 54,405 $13.2M
HSBC Holdings PLC 0.01% Reduce -26.9% 54,155 $13.2M
Two Sigma Securities, LLC 0.63% New 54,142 $13.2M
Edmond DE Rothschild Holding S.A. 0.22% Reduce -18.4% 53,050 $12.9M
Danske Bank A/S 0.05% Reduce -24.7% 52,305 $12.7M
Public Employees Retirement System of Ohio 0.05% Add +0.3% 51,712 $12.6M
Robeco Institutional Asset Management B.V. 0.03% Add +72.2% 49,670 $12.1M
State of New Jersey Common Pension Fund D 0.05% Reduce -33.9% 48,458 $11.8M
Y-Intercept (Hong Kong) Ltd 0.62% Add +1531.7% 46,388 $11.3M
Alliancebernstein L.P. 0.00% Reduce -16.3% 45,373 $11.0M
Tri Locum Partners LP 2.76% New 45,000 $10.9M
Schonfeld Strategic Advisors LLC 0.08% Reduce -81.3% 43,975 $10.7M
Twin Tree Management, LP 0.31% Add +182.1% 43,749 $10.6M
Resona Asset Management Co.,Ltd. 0.06% Reduce -7.4% 43,467 $10.6M
Capital Group Private Client Services, Inc. 0.10% Reduce -20.8% 43,124 $10.5M
Brown Advisory Inc. 0.01% Reduce -6.9% 42,357 $10.3M
Capital Fund Management S.A. 0.12% Add +37.7% 41,821 $10.2M
Russell Investments Group, Ltd. 0.02% Reduce -29.9% 41,185 $10.1M
Sei Investments Co. 0.01% Add +32.3% 39,178 $9.5M
Victory Capital Management Inc. 0.01% Reduce -1.8% 38,680 $9.4M
Trexquant Investment LP 0.14% Reduce -61.0% 37,863 $9.2M
Montanova Capital, LLC 0.37% Add +15.2% 37,624 $9.1M
Acadian Asset Management LLC 0.03% Add +2148.9% 37,310 $9.1M
Bridger Management, LLC 4.63% Reduce -30.0% 37,022 $9.0M
Illinois Municipal Retirement Fund 0.14% Add +39.8% 36,872 $9.0M
USS Investment Management Ltd 0.07% Add +4.0% 36,847 $9.0M
Mackenzie Financial Corp. 0.01% Add +94.9% 36,091 $8.8M
Silverarc Capital Management, LLC 2.16% New 36,000 $8.7M
Rosenblum Silverman Sutton S F Inc. 2.29% Reduce -0.8% 35,200 $8.6M
Artia Global Partners LP 2.18% New 35,000 $8.5M
Arizona State Retirement System 0.06% Add +0.6% 34,736 $8.4M
APG Asset Management US Inc. 0.05% Reduce -5.9% 33,807 $8.2M
Teachers Retirement System of the State of Kentucky 0.07% No change 33,213 $8.1M
Driehaus Capital Management LLC 0.08% New 32,489 $7.9M
Bank of Montreal 0.00% Reduce -69.6% 31,176 $7.7M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.02% — 31,293 $7.6M
Lazard Asset Management LLC 0.01% Add +754.0% 30,805 $7.5M
Hudson Bay Capital Management LP 0.06% Reduce -75.5% 30,000 $7.3M
Tobam 1.13% Reduce -57.0% 29,731 $7.2M
Teacher Retirement System of Texas 0.04% Add +2.9% 29,365 $7.1M
Erste Asset Management GmbH 0.09% No change 28,510 $7.0M
Fjarde AP-fonden (The Fourth Swedish National Pensionfund) 0.08% — 28,415 $6.9M
China Universal Asset Management Co., Ltd. 0.91% Reduce -26.0% 26,509 $6.4M
DNB Asset Management AS 0.03% Add +4.1% 26,015 $6.3M
IFM Investors Pty Ltd 0.06% Add +0.4% 25,754 $6.3M
Burney Co./ 0.24% Reduce -6.0% 25,439 $6.2M
Caisse de depot et placement du Quebec 0.01% Add +2.0% 25,295 $6.1M
Forsta Ap-Fonden 0.05% Reduce -63.1% 25,200 $6.1M
Envestnet Asset Management Inc. 0.00% Reduce -8.4% 25,140 $6.1M
STRS Ohio 0.02% No change 25,000 $6.1M
Atika Capital Management LLC 0.69% New 24,500 $6.0M
Groupama Asset Managment 0.08% Add +974.2% 24,234 $5.9M
BRITISH COLUMBIA INVESTMENT MANAGEMENT Corp 0.04% Add +61.6% 24,217 $5.9M
Weiss Asset Management LP 0.46% Reduce -3.5% 23,800 $5.8M
Ghost Tree Capital, LLC 1.90% Reduce -62.5% 22,500 $5.5M
Xponance LLC 0.05% Add +7.0% 21,076 $5.1M
Utah Retirement Systems 0.06% Reduce -3.7% 20,725 $5.0M
Swedbank AB 0.01% No change 20,639 $5.0M
Panagora Asset Management Inc. 0.02% Add +165.7% 19,810 $4.8M
Privium Fund Management B.V. 1.34% Reduce -7.2% 19,393 $4.8M
Capital Group Investment Management Pte. LTD. 1.03% Add +21.0% 19,570 $4.8M
Tredje AP-fonden 0.05% Reduce -1.6% 19,483 $4.7M
AIA Group Ltd 0.14% Add +32.7% 19,428 $4.7M
Guggenheim Capital LLC 0.03% Reduce -9.3% 19,187 $4.7M
LPL Financial LLC 0.00% Add +9.8% 18,636 $4.5M
EFG Asset Management (North America) Corp. 0.78% Reduce -6.8% 18,584 $4.5M
Allianz Asset Management GmbH 0.01% Add +57.8% 18,174 $4.4M
NEOS Investment Management LLC 0.18% Add +55.2% 17,645 $4.3M
EFG Asset Management (Americas) Corp. 0.81% Add +56.1% 16,992 $4.1M
Raymond James & Associates 0.00% Add +7.2% 16,257 $4.0M
DLD Asset Management, LP 7.95% New 16,200 $3.9M
Nissay Asset Management Corp. /Japan 0.03% Add +3.4% 16,101 $3.9M
Federation des caisses Desjardins du Quebec 0.02% Reduce -4.2% 15,981 $3.9M
Sector Gamma As 1.38% Reduce -44.8% 15,240 $3.7M
FIL Ltd 0.00% Add +47.0% 15,224 $3.7M
KBC Group NV 0.01% No change 15,096 $3.7M
Arrowstreet Capital, Limited Partnership 0.00% New 14,971 $3.6M
Voloridge Investment Management, LLC 0.01% New 14,863 $3.6M
Profund Advisors LLC 0.13% Add +55.4% 14,402 $3.5M
PDT Partners, LLC 0.33% New 14,284 $3.5M
Principal Financial Group Inc. 0.00% Reduce -26.7% 14,189 $3.4M
Silvant Capital Management LLC 0.15% No change 13,661 $3.3M
Mirae Asset Global Investments Co., Ltd. 0.02% Reduce -78.9% 13,192 $3.3M
Public Employees Retirement Association of Colorado 0.01% Reduce -3.5% 13,384 $3.3M
Jacobs Levy Equity Management, Inc. 0.01% Reduce -89.5% 13,283 $3.2M
Gotham Asset Management 0.04% Add +546.6% 13,237 $3.2M
Comerica Bank 0.01% Reduce -3.2% 12,588 $3.1M
Sectoral Asset Management Inc. 1.23% Reduce -32.4% 12,480 $3.0M
PNC Financial Services Group, Inc. 0.00% Add +1.7% 12,399 $3.0M
Toronto Dominion Bank 0.00% Reduce -6.4% 12,151 $3.0M
Sumitomo Mitsui DS Asset Management Company, Ltd 0.03% Add +27.6% 12,114 $2.9M
Portman Square Capital LLP 2.24% Reduce -26.1% 11,848 $2.9M
Tidal Investments LLC 0.04% Add +14.1% 11,733 $2.9M
Elo Mutual Pension Insurance Co 0.06% Reduce -0.8% 11,372 $2.8M
Daiwa Securities Group Inc. 0.01% Add +3.4% 11,292 $2.7M
Storebrand Asset Management As 0.01% Reduce -39.0% 11,286 $2.7M
Aviva PLC 0.01% Add +127.9% 10,891 $2.6M
Penserra Capital Management LLC 0.03% Add +120200.0% 10,827 $2.6M
Cullen/Frost Bankers, Inc. 0.04% Reduce -0.1% 10,555 $2.6M
Gulf International Bank (UK) Ltd 0.06% No change 10,328 $2.5M
Polar Asset Management Partners Inc. 0.10% Reduce -55.8% 10,000 $2.4M
Maryland State Retirement & Pension System 0.04% No change 9,836 $2.4M
Readystate Asset Management LP 0.20% New 9,600 $2.3M
Nordea Investment Management AB 0.00% Add +5.1% 9,434 $2.3M
Quantitative Investment Management, LLC 0.25% Add +169.1% 9,336 $2.3M
MBB Public Markets I LLC 0.05% New 9,200 $2.2M
LMR Partners LLP 0.06% Reduce -87.4% 8,971 $2.2M
Pinebridge Investments, L.P. 0.02% Reduce -33.3% 8,910 $2.2M
Simplex Trading, LLC 0.07% New 8,803 $2.1M
Assetmark, Inc. 0.01% Add +11.9% 8,486 $2.1M
M&T Bank Corp 0.01% Add +31.3% 8,439 $2.1M
Vontobel Holding Ltd. 0.01% Reduce -3.2% 8,413 $2.0M
Amalgamated Bank 0.02% Add +3.7% 8,354 $2.0M
Nisa Investment Advisors, LLC 0.01% No change 8,155 $2.0M
Wealthfront Advisers LLC 0.01% Add +0.1% 8,096 $2.0M
Creative Planning 0.00% Add +63.2% 8,034 $2.0M
Mariner, LLC 0.00% Add +14.4% 7,887 $1.9M
ProShare Advisors LLC 0.01% Reduce -11.5% 7,809 $1.9M
Employees Retirement System of Texas 0.02% No change 7,717 $1.9M
Values First Advisors, Inc. 1.10% Reduce -1.9% 7,590 $1.8M
MetLife Investment Management, LLC 0.01% Add +13.0% 7,462 $1.8M
Verition Fund Management LLC 0.02% Add +68.7% 7,415 $1.8M
FORA Capital, LLC 0.21% New 7,173 $1.7M
Vanguard Personalized Indexing Management, LLC 0.03% Add +17.5% 7,153 $1.7M
Intech Investment Management LLC 0.02% Reduce -34.4% 7,145 $1.7M
US Bancorp \de 0.00% Add +8.1% 7,094 $1.7M
Engineers Gate Manager LP 0.04% Reduce -71.4% 7,074 $1.7M
J. Safra Sarasin Holding AG 0.03% — 6,871 $1.7M
Entropy Technologies, LP 0.18% New 6,849 $1.7M
Cibc World Markets Corp. 0.01% Add +32.7% 6,818 $1.7M
Cinctive Capital Management LP 0.09% Reduce -2.9% 6,781 $1.6M
Gateway Investment Advisers LLC 0.02% Reduce -64.9% 6,677 $1.6M
Bank of Nova Scotia 0.00% Reduce -50.4% 6,634 $1.6M
Advisory Services Network, LLC 0.03% New 6,569 $1.6M
Nomura Holdings Inc. 0.01% New 6,426 $1.6M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Reduce -8.4% 6,074 $1.5M
Edgestream Partners, L.P. 0.07% Reduce -74.1% 6,052 $1.5M
Stifel Financial Corp. 0.00% Reduce -28.8% 5,939 $1.4M
Commonwealth Equity Services, LLC 0.00% Add +2.8% 5,752 $1.4M
Bokf, NA 0.03% Reduce -14.3% 5,751 $1.4M
S&co Inc. 0.10% No change 5,750 $1.4M
Ostrum Asset Management 0.12% Reduce -7.2% 5,742 $1.4M
Pathstone Holdings, LLC 0.01% Add +45.7% 5,620 $1.4M
Cerity Partners LLC 0.00% Add +74.6% 5,574 $1.4M
Inceptionr LLC 0.37% New 5,397 $1.3M
Knollwood Investment Advisory, LLC 0.14% New 5,355 $1.3M
Liontrust Investment Partners LLP 0.02% Add +3288.7% 5,083 $1.2M
Quattro Financial Advisors LLC 0.32% No change 5,000 $1.2M
Diversified Trust Co. 0.03% New 4,978 $1.2M
Prelude Capital Management, LLC 0.10% Reduce -28.8% 4,933 $1.2M
E Fund Management Co., Ltd. 0.07% Add +75.0% 4,926 $1.2M
Atom Investors LP 0.12% Add +16.0% 4,800 $1.2M
Healthcare of Ontario Pension Plan Trust Fund 0.00% New 4,744 $1.2M
Beacon Investment Advisory Services, Inc. 0.05% Reduce -7.6% 4,636 $1.1M
Commerce Bank 0.01% Reduce -0.8% 4,617 $1.1M
Advisors Asset Management, Inc. 0.02% Add +13.4% 4,578 $1.1M
BI Asset Management Fondsmaeglerselskab A/S 0.02% Add +22.5% 4,562 $1.1M
OMERS ADMINISTRATION Corp 0.01% New 4,361 $1.1M
Brandywine Managers, LLC 1.12% No change 4,348 $1.1M
State of Alaska, Department of Revenue 0.01% New 4,275 $1.0M
Machina Capital S.A.S. 0.47% New 4,266 $1.0M
CIBC Asset Management Inc 0.00% Add +5.6% 4,249 $1.0M
Wealth Enhancement Advisory Services, LLC 0.00% Add +40.2% 4,131 $1.0M
Gilbert & Cook, Inc. 0.14% Reduce -9.4% 4,061 $987K
B. Metzler seel. Sohn & Co. AG 0.01% Add +2.5% 4,017 $976K
Achmea Investment Management B.V. 0.02% No change 4,014 $975K
J.P. Marvel Investment Advisors, LLC 0.16% No change 4,000 $972K
Howland Capital Management LLC 0.05% No change 4,000 $972K
First Hawaiian Bank 0.03% No change 4,000 $972K
Clearstead Trust, LLC 0.24% No change 3,981 $967K
Tokio Marine Asset Management Co. Ltd. 0.05% Add +3.2% 3,973 $965K
GraniteShares Advisors LLC 0.31% Add +21.8% 3,870 $940K
Prudential Financial Inc. 0.00% Reduce -5.2% 3,659 $889K
CI Investments Inc. 0.00% Reduce -6.9% 3,622 $880K
Spectrum Planning & Advisory Services Inc. 0.85% — 3,560 $879K
Captrust Financial Advisors 0.00% Reduce -1.2% 3,596 $874K
Orion Capital Management LLC 0.46% Reduce -2.7% 3,575 $869K
SteelPeak Wealth, LLC 0.04% Reduce -48.3% 3,546 $862K
Plato Investment Management Ltd 0.08% Reduce -21.7% 3,529 $858K
Ethic Inc. 0.02% Reduce -11.3% 3,527 $857K
Souders Financial Advisors 0.13% Add +1.0% 3,512 $853K
Sanders Morris Harris LLC 0.14% No change 3,500 $851K
Cwm, LLC 0.00% Add +102.8% 3,492 $849K
Exchange Traded Concepts, LLC 0.02% Reduce -9.4% 3,432 $834K
Boothbay Fund Management, LLC 0.03% Reduce -77.5% 3,386 $823K
Regal Investment Advisors LLC 0.05% Add +4.1% 3,348 $814K
Sequoia Financial Advisors, LLC 0.01% Add +13.7% 3,308 $804K
Nixon Peabody Trust Co. 0.07% No change 3,300 $802K
Hall Laurie J Trustee 0.28% No change 3,250 $790K
Aquatic Capital Management LLC 0.03% Reduce -85.3% 3,200 $778K
Janney Montgomery Scott LLC 0.00% Add +13.8% 3,157 $767K
World Equity Group, Inc. 0.23% No change 3,155 $767K
Choreo, LLC 0.01% New 3,109 $756K
Andra AP-fonden 0.01% New 3,100 $753K
Orion Porfolio Solutions, LLC 0.01% Add +43.8% 3,084 $749K
Orion Portfolio Solutions, LLC 0.01% Add +43.8% 3,084 $749K
Ieq Capital, LLC 0.01% Add +104.0% 3,040 $739K
UniSuper Management Pty Ltd 0.01% Add +66.7% 3,000 $729K
Metis Global Partners, LLC 0.02% Add +1.2% 2,975 $723K
First Trust Direct Indexing L.P. 0.04% Add +10.8% 2,942 $715K
MML Investors Services, LLC 0.00% Reduce -30.0% 2,920 $710K
Horizon Kinetics Asset Management LLC 0.01% No change 2,880 $700K
Prudential PLC 0.00% No change 2,873 $698K
Investment Management Corp of Ontario 0.02% Add +40.3% 2,785 $677K
Cetera Investment Advisers 0.00% Reduce -23.0% 2,739 $666K
Greenleaf Trust 0.01% Reduce -5.0% 2,720 $661K
PEAK6 Investments LLC 0.03% Reduce -67.3% 2,678 $651K
HighVista Strategies LLC 0.23% New 2,602 $632K
Harbor Capital Advisors, Inc. 0.05% Add +0.4% 2,578 $626K
Credit Agricole S A 0.00% New 2,573 $625K
Graham Capital Management, L.P. 0.04% Reduce -70.0% 2,480 $603K
Corebridge Financial, Inc. 0.00% — 2,340 $569K
Integrated Wealth Concepts LLC 0.01% Reduce -0.3% 2,314 $562K
Jefferies Financial Group Inc. 0.01% Add +24.9% 2,300 $559K
New York Life Investment Management LLC 0.01% Add +2.0% 2,263 $550K
Quantinno Capital Management LP 0.01% New 2,240 $544K
Raymond James Financial Services Advisors, Inc. 0.00% Reduce -29.3% 2,197 $534K
Kennedy Capital Management LLC 0.01% Add +40.7% 2,178 $529K
Monograph Wealth Advisors, LLC 0.08% No change 2,126 $517K
Altfest L J & Co. Inc. 0.07% Add +0.6% 2,112 $513K
Virtus Advisers, LLC 0.25% Add +0.7% 2,058 $500K
Vestcor Inc 0.02% No change 2,038 $495K
Meiji Yasuda Asset Management Co Ltd. 0.02% Add +15.3% 2,030 $493K
Security National Bank of So Dak 0.29% No change 2,000 $486K
Pallas Capital Advisors LLC 0.02% New 2,052 $486K
Bridgefront Capital, LLC 0.20% Add +6.9% 1,998 $486K
Algert Global LLC 0.02% New 1,960 $476K
Loring Wolcott & Coolidge Fiduciary Advisors LLP 0.00% No change 1,905 $476K
Swiss Life Asset Management Ltd 0.01% New 1,949 $474K
Motley Fool Asset Management LLC 0.03% Reduce -3.6% 1,890 $460K
ADAR1 Capital Management, LLC 0.09% Reduce -99.0% 1,850 $450K
Gsa Capital Partners LLP 0.03% New 1,842 $448K
Bleakley Financial Group, LLC 0.01% Reduce -8.4% 1,776 $432K
Simplicity Wealth,LLC 0.01% Reduce -8.5% 1,770 $430K
Rakuten Investment Management, Inc. 0.00% Add +60.1% 1,739 $430K
Atria Investments, Inc 0.01% New 1,758 $427K
Vident Advisory, LLC 0.01% Add +12.0% 1,749 $425K
Fort Sheridan Advisors LLC 0.07% New 1,733 $421K
Truist Financial Corp. 0.00% Reduce -26.5% 1,728 $420K
Oppenheimer & Co. Inc. 0.01% No change 1,716 $417K
Empowered Funds, LLC 0.01% Reduce -87.7% 1,702 $414K
Emerald Advisers, LLC 0.02% Reduce -21.8% 1,618 $393K
Yousif Capital Management, LLC 0.00% Reduce -1.4% 1,613 $392K
Proficio Capital Partners LLC 0.04% Reduce -22.7% 1,582 $384K
United Capital Financial Advisors, LLC 0.00% New 1,520 $369K
Mutual of America Capital Management LLC 0.00% No change 1,519 $369K
Beacon Pointe Advisors, LLC 0.00% Reduce -7.6% 1,512 $367K
High Net Worth Advisory Group LLC 0.11% No change 1,500 $365K
Focus Partners Wealth 0.00% New 1,493 $363K
XTX Topco Ltd 0.03% Reduce -69.2% 1,480 $360K
Westpac Banking Corp. 0.03% No change 1,467 $356K
Forum Financial Management, LP 0.01% No change 1,457 $354K
Sanctuary Advisors, LLC 0.00% — 2,377 $341K
Kestra Advisory Services, LLC 0.00% Add +2.4% 1,391 $338K
Ballentine Partners, LLC 0.01% New 1,389 $338K
Signaturefd, LLC 0.01% Add +25.8% 1,383 $336K
Cresset Asset Management, LLC 0.00% New 1,379 $335K
Wedmont Private Capital 0.02% New 1,234 $321K
Everhart Financial Group, Inc. 0.08% New 1,322 $321K
Cigna Investments Inc. 0.06% Reduce -2.2% 1,322 $321K
Walleye Trading LLC 0.01% Reduce -94.8% 1,318 $320K
North Star Asset Management Inc. 0.02% Reduce -13.3% 1,310 $318K
Great Lakes Advisors, LLC 0.00% New 1,299 $316K
Freedom Investment Management, Inc. 0.03% New 1,285 $312K
JGP Global Gestao de Recursos Ltda. 0.38% New 1,233 $300K
Osaic Holdings, Inc. 0.00% Reduce -23.9% 1,190 $289K
Los Angeles Capital Management LLC 0.00% Reduce -59.9% 1,188 $289K
Ossiam 0.01% Add +5.5% 1,166 $283K
Laird Norton Wetherby Wealth Management, LLC 0.01% Reduce -20.5% 1,149 $279K
Peregrine Capital Management LLC 0.01% No change 1,147 $279K
Symmetry Partners, LLC 0.01% New 1,144 $278K
Envestnet Portfolio Solutions, Inc. 0.00% Reduce -19.2% 1,139 $277K
Clearstead Advisors, LLC 0.00% Add +909.1% 1,110 $270K
Plante Moran Financial Advisors, LLC 0.03% No change 1,100 $267K
GTS Securities LLC 0.01% New 1,096 $266K
Daiichi Life Insurance Co., Ltd. 0.01% New 1,077 $262K
Central Pacific Bank - Trust Division 0.03% No change 1,050 $255K
Breakwater Capital Group 0.06% New 1,025 $249K
EntryPoint Capital, LLC 0.12% Reduce -40.9% 1,019 $248K
Fulton Bank, N.A. 0.01% New 1,018 $247K
Westmount Partners, LLC 0.08% New 1,005 $245K
NJ State Employees Deferred Compensation Plan 0.03% New 1,000 $243K
Centiva Capital, LP 0.01% New 1,000 $243K
NewEdge Advisors, LLC 0.00% Add +5427.8% 995 $242K
O'shaughnessy Asset Management, LLC 0.00% Reduce -54.5% 993 $241K
Tower Research Capital LLC (TRC) 0.00% Reduce -43.9% 973 $236K
Summit Trail Advisors, LLC 0.01% New 929 $226K
Merit Financial Group, LLC 0.01% New 928 $226K
HCR Wealth Advisors 0.03% New 924 $225K
Crossmark Global Holdings, Inc. 0.00% New 918 $223K
Humankind Investments LLC 0.06% Reduce -40.2% 916 $223K
FUKOKU MUTUAL LIFE INSURANCE Co 0.02% New 914 $222K
Moloney Securities Asset Management, LLC 0.03% Reduce -62.0% 907 $220K
Meridian Financial Advisors, LLC 0.16% New 900 $219K
SYM FINANCIAL Corp 0.03% New 892 $217K
Steward Partners Investment Advisory, LLC 0.00% Add +24.5% 890 $216K
Nwam LLC 0.06% New 852 $207K
Towarzystwo Funduszy Inwestycyjnych Pzu SA 0.08% No change 850 $207K
Coldstream Capital Management Inc. 0.01% New 843 $205K
TD Waterhouse Canada Inc. 0.00% Reduce -1.1% 836 $203K
Chapin Davis, Inc. 0.07% New 825 $200K
Covestor Ltd 0.12% Add +6.0% 776 $189K
CSS LLC 0.04% New 700 $170K
National Bank of Canada 0.00% Reduce -99.4% 626 $152K
Northwestern Mutual Wealth Management Co. 0.00% Add +72.3% 596 $145K
Wolverine Asset Management LLC 0.01% No change 590 $143K
Allworth Financial LP 0.00% Reduce -4.4% 565 $134K
1832 Asset Management L.P. 0.00% No change 545 $132K
Lindbrook Capital, LLC 0.01% Add +117.4% 513 $125K
Arax Advisory Partners 0.01% New 481 $117K
Pacer Advisors, Inc. 0.00% Add +61.8% 461 $112K
SG Americas Securities, LLC 0.00% Reduce -98.9% 437 $106K
GAMMA Investing LLC 0.01% Add +97.2% 416 $101K
Alta Advisers Ltd 0.05% No change 400 $97K
Parallel Advisors, LLC 0.00% Add +64.2% 399 $97K
Paloma Partners Management Co 0.01% Reduce -88.4% 378 $92K
Spire Wealth Management 0.00% Reduce -35.3% 377 $92K
Benjamin F. Edwards & Company, Inc. 0.00% Reduce -11.9% 356 $87K
V-Square Quantitative Management LLC 0.01% Add +21.9% 334 $81K
Itau Unibanco Holding S.A. 0.00% New 327 $79K
Meeder Asset Management Inc. 0.01% Add +1237.5% 321 $78K
EverSource Wealth Advisors, LLC 0.00% Add +8.8% 298 $71K
Natixis 0.00% Reduce -57.3% 291 $71K
Prestige Wealth Management Group LLC 0.01% Reduce -42.4% 272 $66K
Allspring Global Investments Holdings, LLC 0.00% Add +54.2% 259 $63K
Quadrant Capital Group LLC 0.00% Reduce -0.4% 230 $56K
Quarry LP 0.02% Reduce -77.6% 224 $54K
CKW Financial Group 0.01% No change 200 $49K
Concord Wealth Partners 0.01% New 200 $49K
Anchor Investment Management, LLC 0.01% No change 200 $49K
Livforsakringsbolaget Skandia, Omsesidigt 0.00% No change 200 $49K
Capital Advisors, Ltd. LLC 0.01% Add +1.3% 162 $39K
Harbour Investments, Inc. 0.00% Add +23.5% 126 $31K
Brown, Lisle/Cummings, Inc. 0.01% No change 125 $30K
Global Trust Asset Management, LLC 0.01% No change 122 $30K
Smartleaf Asset Management LLC 0.00% Add +1050.0% 115 $28K
Principal Securities, Inc. 0.00% Add +27.8% 115 $28K
Gradient Investments LLC 0.00% Add +0.9% 113 $27K
Farther Finance Advisors, LLC 0.00% Add +56.5% 108 $26K
Ashton Thomas Private Wealth, LLC 0.00% New 108 $26K
Sandy Spring Bank 0.00% No change 106 $26K
nVerses Capital, LLC 0.01% New 100 $24K
Hartford Financial Management Inc. 0.01% New 100 $24K
Cape Investment Advisory, Inc. 0.01% No change 90 $22K
First Horizon Advisors, Inc. 0.00% Reduce -1.1% 87 $21K
Annis Gardner Whiting Capital Advisors, LLC 0.01% No change 72 $17K
Rakuten Securities, Inc. 0.01% Reduce -67.5% 65 $16K
Versant Capital Management, Inc 0.00% Add +1966.7% 62 $15K
TFC Financial Management, Inc. 0.00% Add +5.9% 54 $13K
Blue Trust, Inc. 0.00% Add +480.0% 87 $13K
Global Retirement Partners, LLC 0.00% Reduce -15.9% 53 $13K
St. Johns Investment Management Company, LLC 0.01% No change 50 $12K
Peoples Financial Services Corp. 0.01% No change 50 $12K
Princeton Global Asset Management LLC 0.00% No change 50 $12K
IFP Advisors, Inc 0.00% Reduce -89.6% 49 $12K
Huntington National Bank 0.00% Reduce -26.9% 49 $12K
Parkside Financial Bank & Trust 0.00% Add +13.9% 41 $10K
MassMutual Private Wealth & Trust, FSB 0.00% Add +2.6% 39 $9K
Bogart Wealth, LLC 0.00% No change 36 $9K
Whittier Trust Co. 0.00% No change 36 $9K
Bell Investment Advisors, Inc 0.00% Reduce -2.8% 35 $9K
Sachetta, LLC 0.00% Add +57.9% 30 $7K
Larson Financial Group LLC 0.00% No change 27 $7K
Brown Brothers Harriman & Co. 0.00% No change 27 $7K
MV Capital Management, Inc. 0.00% Add +420.0% 26 $6K
Valley National Advisers Inc. 0.00% Add +66.7% 25 $6K
Concourse Financial Group Securities, Inc. 0.00% Add +4.8% 22 $5K
JFS Wealth Advisors, LLC 0.00% No change 21 $5K
Zions Bancorporation, N.A. 0.00% Add +42.9% 20 $5K
Cetera Trust Company, N.A 0.00% No change 16 $4K
Quent Capital, LLC 0.00% Reduce -90.6% 16 $4K
Semmax Financial Advisors Inc. 0.00% No change 14 $4K
Piscataqua Savings Bank 0.00% No change 15 $4K
FinTrust Capital Advisors, LLC 0.00% New 15 $4K
Sunbelt Securities, Inc. 0.00% No change 15 $4K
Cornerstone Planning Group LLC 0.00% New 13 $3K
Unique Wealth Strategies, LLC 0.00% New 23 $3K
WFA Asset Management Corp 0.00% No change 14 $3K
Front Row Advisors LLC 0.00% No change 14 $3K
Raffa Wealth Management, LLC 0.00% No change 13 $3K
Avion Wealth 0.00% Add +150.0% 15 $3K
Quantbot Technologies LP 0.00% Reduce -97.5% 11 $3K
Mark Sheptoff Financial Planning, LLC 0.00% No change 10 $2K
AdvisorNet Financial, Inc 0.00% Reduce -56.5% 10 $2K
Avior Wealth Management, LLC 0.00% No change 9 $2K
Private Wealth Management Group, LLC 0.00% Reduce -76.5% 8 $2K
Janiczek Wealth Management, LLC 0.00% No change 8 $2K
LRI Investments, LLC 0.00% New 8 $2K
Criterion Capital Advisors, LLC 0.00% No change 7 $2K
DiNuzzo Private Wealth, Inc. 0.00% Add +16.7% 7 $2K
Mather Group, Llc. 0.00% Add +42.9% 10 $1K
Richardson Financial Services Inc. 0.00% Reduce -50.0% 5 $1K
Fifth Third Bancorp 0.00% Reduce -37.5% 5 $1K
Montag A & Associates Inc. 0.00% No change 5 $1K
Winthrop Capital Management, LLC 0.00% No change 6 $1K
SJS Investment Consulting Inc. 0.00% Reduce -20.0% 4 $972
JNBA Financial Advisors 0.00% No change 4 $972
Manchester Capital Management LLC 0.00% Reduce -33.3% 2 $486
CoreCap Advisors, LLC 0.00% No change 2 $486
True Wealth Design, LLC 0.00% Reduce -50.0% 1 $243
Harbor Investment Advisory, LLC 0.00% New 1 $243
Johnson Financial Group, Inc. 0.00% New 1 $243

"% of holder's portfolio" is ALNY's weight in each manager's 13F, not the share of Alnylam Pharmaceuticals Inc. the manager owns.