Apellis PharmaceuticalsAPLS
13F holders, Q1 2024 (March 31)302holders
6famous investors
$58.76avg. 13F price*
At the end of Q1 2024, 302 institutions reported holding Apellis Pharmaceuticals Inc. (APLS) in their 13F filings. The largest holders were Wellington Management Group LLP ($885.1M), EcoR1 Capital, LLC ($667.6M) and Avoro Capital Advisors LLC ($653.1M). 6 famous investors held it, including Ken Griffin (0.1% of Citadel Advisors's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Apellis Pharmaceuticals Inc.
- CUSIP
- 03753U106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 65 | $223.7M |
| Exits | 46 | $97.3M |
Ownership 302 holders
| Wellington Management Group LLP | 0.16% | Reduce -8.4% | 15,058,071 | $885.1M |
| EcoR1 Capital, LLC | 16.97% | Add +1.6% | 11,357,425 | $667.6M |
| Avoro Capital Advisors LLC | 7.62% | No change | 11,111,111 | $653.1M |
| Vanguard Group Inc. | 0.01% | Reduce -0.5% | 9,505,866 | $558.8M |
| BlackRock Inc. | 0.01% | Add +2.1% | 5,494,591 | $323.0M |
| T. Rowe Price Investment Management, Inc. | 0.17% | Reduce -26.9% | 4,605,721 | $270.7M |
| Jennison Associates LLC | 0.13% | Reduce -1.1% | 3,240,513 | $190.5M |
| State Street Corp. | 0.01% | Reduce -0.2% | 2,909,528 | $171.0M |
| Octagon Capital Advisors LP | 20.06% | No change | 2,806,980 | $165.0M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -0.0% | 2,459,246 | $144.6M |
| JPMorgan Chase & Co. | 0.01% | Reduce -14.0% | 2,214,309 | $130.2M |
| FMR LLC | 0.01% | Add +4.1% | 2,178,742 | $128.1M |
| Assenagon Asset Management S.A. | 0.32% | Reduce -5.7% | 2,023,614 | $118.9M |
| Boxer Capital, LLC | 5.01% | No change | 1,726,000 | $101.5M |
| Geode Capital Management, LLC | 0.01% | Add +3.6% | 1,689,890 | $99.4M |
| Morgan Stanley | 0.01% | Reduce -47.1% | 1,637,618 | $96.3M |
| Deutsche Bank AG | 0.04% | Add +88.1% | 1,611,773 | $94.7M |
| Artal Group S.A. | 1.99% | Reduce -7.5% | 1,315,282 | $77.3M |
| Orbimed Advisors LLC | 1.40% | Add +40.7% | 1,297,800 | $76.3M |
| Citadel Advisors | 0.07% | Add +316.0% | 1,186,082 | $69.7M |
| Pictet Asset Management Holding SA | 0.07% | Reduce -20.2% | 1,073,234 | $63.0M |
| Polar Capital Holdings Plc | 0.33% | Add +0.1% | 1,054,440 | $62.0M |
| Norges Bank | 0.01% | Add +6.5% | 1,007,920 | $59.2M |
| Deep Track Capital, LP | 1.69% | New | 1,000,000 | $58.8M |
| Fiera Capital Corp | 0.16% | Add +3.2% | 948,437 | $55.7M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +2.2% | 924,562 | $54.3M |
| Frazier Life Sciences Management, L.P. | 2.20% | No change | 885,165 | $52.0M |
| Eagle Asset Management Inc. | 0.26% | Add +89.6% | 845,533 | $50.5M |
| Logos Global Management LP | 4.95% | Reduce -15.8% | 800,000 | $47.0M |
| Millennium Management | 0.04% | Add +6169.6% | 785,396 | $46.2M |
| Invesco Ltd. | 0.01% | Add +46.9% | 762,115 | $44.8M |
| Bank of America Corp. | 0.00% | Add +66.6% | 723,444 | $42.5M |
| Candriam S.C.A. | 0.22% | Add +73.3% | 584,925 | $34.4M |
| Iron Triangle Partners LP | 3.35% | New | 550,000 | $32.3M |
| Ameriprise Financial Inc. | 0.01% | Reduce -6.0% | 531,362 | $31.2M |
| Driehaus Capital Management LLC | 0.29% | Add +4.5% | 503,039 | $29.6M |
| Voya Investment Management LLC | 0.03% | Add +92.8% | 494,692 | $29.1M |
| Victory Capital Management Inc. | 0.03% | Reduce -20.2% | 491,897 | $28.9M |
| Bellevue Group AG | 0.42% | Reduce -42.3% | 473,915 | $27.9M |
| TD Asset Management Inc | 0.03% | Reduce -5.0% | 459,402 | $27.0M |
| Northern Trust Corp. | 0.00% | Reduce -1.8% | 440,456 | $25.9M |
| First Trust Advisors LP | 0.02% | Add +332.6% | 406,483 | $23.9M |
| Cormorant Asset Management, LP | 1.04% | Reduce -36.0% | 400,000 | $23.5M |
| New York State Common Retirement Fund | 0.03% | Reduce -4.3% | 325,926 | $19.2M |
| Bank of New York Mellon Corp | 0.00% | Reduce -13.3% | 322,922 | $19.0M |
| Goldman Sachs Group Inc. | 0.00% | Add +2.9% | 319,476 | $18.8M |
| Altitude Crest Partners Inc. | 7.23% | Add +88.8% | 287,277 | $16.9M |
| Nuveen Asset Management, LLC | 0.00% | Add +0.0% | 270,576 | $15.9M |
| Point72 Asset Management | 0.05% | New | 267,823 | $15.7M |
| Citigroup Inc. | 0.02% | Add +202.4% | 261,708 | $15.4M |
| Ensign Peak Advisors, Inc | 0.03% | Add +6.0% | 260,274 | $15.3M |
| Prudential Financial Inc. | 0.02% | Reduce -24.8% | 245,560 | $14.4M |
| Susquehanna International Group, LLP | 0.02% | Reduce -36.2% | 244,261 | $14.4M |
| Fiduciary Trust Co | 0.22% | Reduce -0.7% | 240,986 | $14.2M |
| Balyasny Asset Management L.P. | 0.04% | New | 232,243 | $13.7M |
| Franklin Resources Inc. | 0.00% | Reduce -1.4% | 226,649 | $13.3M |
| Vestal Point Capital, LP | 1.09% | New | 225,000 | $13.2M |
| Macquarie Group Ltd. | 0.01% | Reduce -62.0% | 221,654 | $13.0M |
| 683 Capital Management, LLC | 1.39% | Add +65.4% | 215,000 | $12.6M |
| Eventide Asset Management, LLC | 0.19% | No change | 209,794 | $12.3M |
| Amundi | 0.01% | Add +3.0% | 248,483 | $11.8M |
| Aberdeen Group plc | 0.02% | Add +12.3% | 189,813 | $11.2M |
| Woodline Partners LP | 0.10% | Add +0.4% | 186,998 | $11.0M |
| Rhenman & Partners Asset Management AB | 0.99% | Add +77.7% | 178,395 | $10.5M |
| Marshall Wace, LLP | 0.02% | Reduce -25.6% | 171,873 | $10.1M |
| Affinity Asset Advisors, LLC | 1.70% | Add +120.0% | 165,000 | $9.7M |
| Redmile Group, LLC | 0.33% | New | 155,000 | $9.1M |
| Integral Health Asset Management, LLC | 0.87% | New | 150,000 | $8.8M |
| Rafferty Asset Management, LLC | 0.03% | Add +4.0% | 148,801 | $8.7M |
| California Public Employees Retirement System | 0.01% | No change | 145,833 | $8.6M |
| Wells Fargo & Company | 0.00% | Add +9.4% | 145,035 | $8.5M |
| Swiss National Bank | 0.01% | Reduce -13.6% | 140,300 | $8.2M |
| Senator Investment Group LP | 0.38% | New | 140,000 | $8.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -1.7% | 139,325 | $8.2M |
| Bank of Montreal | 0.00% | Reduce -71.7% | 132,937 | $7.8M |
| Ghost Tree Capital, LLC | 2.46% | New | 130,000 | $7.6M |
| Jane Street Group, LLC | 0.01% | Reduce -70.3% | 129,009 | $7.6M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +16.4% | 123,330 | $7.2M |
| Rhumbline Advisers | 0.01% | Reduce -9.5% | 120,921 | $7.1M |
| Allspring Global Investments Holdings, LLC | 0.01% | Add +94.8% | 115,453 | $6.8M |
| UBS Group AG | 0.00% | Add +17.1% | 111,292 | $6.5M |
| Walleye Capital LLC | 0.08% | Reduce -25.0% | 110,799 | $6.5M |
| Royal Bank of Canada | 0.00% | Reduce -13.8% | 101,334 | $6.0M |
| HSBC Holdings PLC | 0.00% | New | 98,550 | $5.8M |
| Envestnet Asset Management Inc. | 0.00% | Add +9.5% | 94,605 | $5.6M |
| Peregrine Capital Management LLC | 0.16% | New | 92,660 | $5.4M |
| Lisanti Capital Growth, LLC | 1.28% | Add +92.7% | 89,210 | $5.2M |
| Legal & General Group Plc | 0.00% | Add +2.8% | 85,844 | $5.0M |
| Principal Financial Group Inc. | 0.00% | Add +254.5% | 84,604 | $5.0M |
| PFM Health Sciences, LP | 0.25% | New | 82,952 | $4.9M |
| Credit Suisse AG/ | 0.00% | Reduce -5.8% | 80,642 | $4.7M |
| Bleakley Financial Group, LLC | 0.13% | Add +0.0% | 78,253 | $4.6M |
| Simplicity Wealth,LLC | 0.11% | New | 78,247 | $4.6M |
| Frontier Capital Management Co. LLC | 0.04% | New | 78,048 | $4.6M |
| California State Teachers Retirement System | 0.01% | Reduce -17.5% | 74,370 | $4.4M |
| Saturn V Capital Management LP | 1.68% | Reduce -50.0% | 71,463 | $4.2M |
| HRT Financial LP | 0.02% | Reduce -9.7% | 68,575 | $4.0M |
| Dimensional Fund Advisors LP | 0.00% | Add +91.6% | 68,144 | $4.0M |
| Nisa Investment Advisors, LLC | 0.03% | No change | 67,350 | $4.0M |
| Granahan Investment Management, LLC | 0.14% | Add +57.7% | 66,597 | $3.9M |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -51.1% | 58,610 | $3.4M |
| PDT Partners, LLC | 0.31% | Add +8.8% | 56,521 | $3.3M |
| AQR Capital Management | 0.01% | New | 56,460 | $3.3M |
| Mirae Asset Global Investments Co., Ltd. | 0.01% | New | 50,299 | $3.2M |
| DekaBank Deutsche Girozentrale | 0.01% | No change | 55,000 | $3.2M |
| Lord, Abbett & Co. LLC | 0.01% | New | 54,000 | $3.2M |
| Algert Global LLC | 0.12% | Add +27.0% | 51,978 | $3.1M |
| State of Wisconsin Investment Board | 0.01% | Reduce -23.8% | 51,675 | $3.0M |
| BNP Paribas Financial Markets | 0.00% | Reduce -69.2% | 51,626 | $3.0M |
| Axiom Investors LLC | 0.03% | Add +64.4% | 50,770 | $3.0M |
| Steward Partners Investment Advisory, LLC | 0.03% | Add +69.8% | 50,600 | $3.0M |
| SG Americas Securities, LLC | 0.01% | Reduce -2.8% | 47,535 | $2.8M |
| Treasurer of the State of North Carolina | 0.01% | Add +0.7% | 45,130 | $2.7M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -20.1% | 42,421 | $2.5M |
| Erste Asset Management GmbH | 0.03% | No change | 42,000 | $2.5M |
| Schroder Investment Management Group | 0.00% | Add +70.6% | 40,403 | $2.4M |
| ExodusPoint Capital Management, LP | 0.03% | New | 40,120 | $2.4M |
| Sei Investments Co. | 0.00% | Add +57.4% | 39,864 | $2.3M |
| Public Employees Retirement System of Ohio | 0.01% | Reduce -8.6% | 38,676 | $2.3M |
| Campbell & CO Investment Adviser LLC | 0.19% | New | 38,024 | $2.2M |
| Cubist Systematic Strategies, LLC | 0.02% | Add +71.8% | 36,994 | $2.2M |
| Ikarian Capital, LLC | 0.56% | Add +2.1% | 35,092 | $2.1M |
| Hudson Bay Capital Management LP | 0.02% | New | 35,000 | $2.1M |
| Cinctive Capital Management LP | 0.11% | Add +488.3% | 34,994 | $2.1M |
| Janus Henderson Group PLC | 0.00% | Reduce -7.8% | 34,939 | $2.1M |
| Guggenheim Capital LLC | 0.01% | Add +6.1% | 33,502 | $2.0M |
| Polar Asset Management Partners Inc. | 0.07% | New | 32,200 | $1.9M |
| State Board of Administration of Florida Retirement System | 0.00% | Reduce -66.6% | 28,116 | $1.9M |
| Alliancebernstein L.P. | 0.00% | Add +2.8% | 31,413 | $1.8M |
| Mackenzie Financial Corp. | 0.00% | Reduce -25.2% | 31,021 | $1.8M |
| Caption Management, LLC | 0.20% | Reduce -92.1% | 31,000 | $1.8M |
| Mutual of America Capital Management LLC | 0.02% | Reduce -7.5% | 28,654 | $1.7M |
| Orion Porfolio Solutions, LLC | 0.02% | Add +37.1% | 27,079 | $1.6M |
| Orion Portfolio Solutions, LLC | 0.02% | Add +37.1% | 27,079 | $1.6M |
| Baird Financial Group, Inc. | 0.00% | Add +2.4% | 26,547 | $1.6M |
| Barclays PLC | 0.00% | Reduce -86.9% | 25,792 | $1.5M |
| ADAR1 Capital Management, LLC | 0.41% | New | 25,700 | $1.5M |
| Skandinaviska Enskilda Banken AB (publ) | 0.01% | Reduce -16.1% | 25,581 | $1.5M |
| Boothbay Fund Management, LLC | 0.05% | Add +96.2% | 24,825 | $1.5M |
| China Universal Asset Management Co., Ltd. | 0.17% | Add +69.1% | 23,182 | $1.4M |
| Profund Advisors LLC | 0.05% | Reduce -0.1% | 22,533 | $1.3M |
| Handelsbanken Fonder AB | 0.01% | Reduce -0.9% | 22,400 | $1.3M |
| Assetmark, Inc. | 0.00% | Add +25.4% | 21,747 | $1.3M |
| Stifel Financial Corp. | 0.00% | Add +9.1% | 21,723 | $1.3M |
| Jacobs Levy Equity Management, Inc. | 0.01% | Add +4.7% | 20,057 | $1.2M |
| Arizona State Retirement System | 0.01% | Reduce -15.2% | 19,540 | $1.1M |
| Raymond James & Associates | 0.00% | Add +23.2% | 18,955 | $1.1M |
| Seven Eight Capital, LP | 0.11% | New | 18,442 | $1.1M |
| CIBC Private Wealth Group LLC | 0.00% | Add +0.1% | 17,920 | $1.1M |
| Birchview Capital, LP | 0.86% | No change | 18,000 | $1.1M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -15.6% | 16,979 | $998K |
| CANADA LIFE ASSURANCE Co | 0.00% | Add +107.7% | 16,677 | $981K |
| Edgestream Partners, L.P. | 0.05% | New | 16,031 | $942K |
| Sippican Capital Advisors | 0.73% | Reduce -0.5% | 15,929 | $936K |
| Teacher Retirement System of Texas | 0.01% | Reduce -16.9% | 15,823 | $930K |
| Mariner, LLC | 0.00% | Add +3.3% | 14,365 | $844K |
| Hennion & Walsh Asset Management, Inc. | 0.04% | Add +14.4% | 14,068 | $827K |
| Allianz Asset Management GmbH | 0.00% | No change | 13,600 | $799K |
| Xponance LLC | 0.01% | Reduce -0.9% | 12,805 | $753K |
| MML Investors Services, LLC | 0.00% | Add +21.4% | 12,296 | $723K |
| Wolverine Trading, LLC | 0.01% | Add +83.0% | 12,298 | $723K |
| Cambridge Trust Co. | 0.03% | No change | 11,500 | $676K |
| KPP Advisory Services LLC | 0.18% | Add +1.8% | 11,396 | $670K |
| Raymond James Financial Services Advisors, Inc. | 0.00% | Add +14.9% | 11,307 | $665K |
| Danske Bank A/S | 0.00% | — | 11,180 | $657K |
| Level Four Advisory Services, LLC | 0.04% | Add +2.2% | 10,694 | $640K |
| Neuberger Berman Group LLC | 0.00% | Reduce -14.3% | 10,675 | $627K |
| Brevan Howard Capital Management LP | 0.06% | Add +139.8% | 10,415 | $612K |
| Harvest Management LLC | 0.52% | New | 10,300 | $605K |
| Wynnefield Capital Inc. | 0.23% | No change | 10,000 | $588K |
| Toronto Dominion Bank | 0.00% | New | 9,999 | $588K |
| Legato Capital Management LLC | 0.07% | Add +141.7% | 9,825 | $578K |
| Sectoral Asset Management Inc. | 0.22% | Add +85.3% | 9,670 | $568K |
| Soros Fund Management | 0.02% | New | 8,948 | $526K |
| Snowden Capital Advisors LLC | 0.02% | Reduce -2.9% | 8,898 | $523K |
| Oppenheimer Asset Management Inc. | 0.01% | Add +8.3% | 8,694 | $511K |
| PEAK6 Investments LLC | 0.02% | New | 8,562 | $503K |
| Qube Research & Technologies Ltd | 0.00% | New | 8,481 | $499K |
| ProShare Advisors LLC | 0.00% | Add +11.6% | 8,452 | $497K |
| Public Employees Retirement Association of Colorado | 0.00% | Reduce -14.2% | 8,362 | $492K |
| Comerica Bank | 0.00% | Add +500.7% | 8,163 | $480K |
| Emerald Advisers, LLC | 0.02% | Add +83.0% | 7,751 | $456K |
| Worth Venture Partners, LLC | 3.16% | New | 7,700 | $453K |
| Inceptionr LLC | 0.12% | New | 7,653 | $450K |
| Virtus Advisers, LLC | 0.23% | Add +16.8% | 7,302 | $429K |
| HighVista Strategies LLC | 0.15% | New | 7,266 | $427K |
| E Fund Management Co., Ltd. | 0.03% | Reduce -8.2% | 7,032 | $413K |
| Axq Capital, LP | 0.10% | New | 6,900 | $406K |
| Creative Planning | 0.00% | Add +54.0% | 6,867 | $404K |
| Graham Capital Management, L.P. | 0.02% | New | 6,742 | $396K |
| Maryland State Retirement & Pension System | 0.01% | No change | 7,881 | $391K |
| Amalgamated Bank | 0.00% | Reduce -67.6% | 6,636 | $390K |
| Keybank National Association | 0.00% | Add +0.3% | 6,570 | $386K |
| Moody Aldrich Partners LLC | 0.06% | New | 6,431 | $378K |
| MetLife Investment Management, LLC | 0.00% | Add +0.3% | 6,146 | $361K |
| FIL Ltd | 0.00% | Add +7.6% | 6,108 | $359K |
| DNB Asset Management AS | 0.00% | New | 6,068 | $357K |
| Engineers Gate Manager LP | 0.01% | Add +58.0% | 6,049 | $356K |
| NJ State Employees Deferred Compensation Plan | 0.04% | No change | 6,000 | $353K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 6,000 | $353K |
| Illinois Municipal Retirement Fund | 0.01% | No change | 5,925 | $348K |
| Utah Retirement Systems | 0.00% | No change | 5,600 | $329K |
| Aigen Investment Management, LP | 0.07% | New | 5,560 | $327K |
| Stelac Advisory Services LLC | 0.15% | No change | 5,520 | $324K |
| GTS Securities LLC | 0.01% | Reduce -89.4% | 5,497 | $323K |
| XTX Topco Ltd | 0.04% | New | 5,440 | $320K |
| Readystate Asset Management LP | 0.02% | New | 5,438 | $320K |
| M&T Bank Corp | 0.00% | Add +12.6% | 5,271 | $310K |
| LPL Financial LLC | 0.00% | New | 5,227 | $307K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Add +8.1% | 5,075 | $298K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -31.4% | 4,919 | $289K |
| Pathstone Holdings, LLC | 0.00% | Reduce -6.0% | 4,611 | $271K |
| Cipher Capital LP | 0.12% | New | 4,568 | $269K |
| Tidal Investments LLC | 0.00% | New | 4,527 | $266K |
| Summit Trail Advisors, LLC | 0.01% | New | 4,465 | $262K |
| Cerity Partners LLC | 0.00% | New | 4,281 | $252K |
| Pearl River Capital, LLC | 0.04% | New | 4,259 | $250K |
| Ethic Inc. | 0.01% | New | 4,103 | $241K |
| Prime Capital Investment Advisors, LLC | 0.00% | Add +4.9% | 4,004 | $235K |
| Compagnie Lombard Odier SCmA | 0.00% | No change | 4,000 | $235K |
| Integrated Wealth Concepts LLC | 0.00% | Reduce -22.6% | 3,867 | $227K |
| Whittier Trust Co. | 0.00% | No change | 3,700 | $217K |
| IFP Advisors, Inc | 0.01% | Reduce -0.8% | 3,698 | $217K |
| Russell Investments Group, Ltd. | 0.00% | Add +1300.8% | 3,586 | $211K |
| US Bancorp \de | 0.00% | Reduce -7.1% | 3,566 | $210K |
| Gotham Asset Management | 0.00% | No change | 3,513 | $206K |
| Woodward Diversified Capital, LLC | 0.13% | No change | 3,500 | $206K |
| Oppenheimer & Co. Inc. | 0.00% | Reduce -71.4% | 3,500 | $206K |
| Altfest L J & Co. Inc. | 0.03% | Reduce -26.1% | 3,414 | $201K |
| Knights of Columbus Asset Advisors LLC | 0.01% | Reduce -48.8% | 3,172 | $186K |
| Osaic Holdings, Inc. | 0.00% | Reduce -49.9% | 3,001 | $176K |
| Quarry LP | 0.07% | New | 3,000 | $176K |
| CI Investments Inc. | 0.00% | Add +1813.5% | 2,832 | $166K |
| Lazard Asset Management LLC | 0.00% | Reduce -96.6% | 2,808 | $165K |
| Handelsinvest Investeringsforvaltning | 0.08% | Reduce -34.2% | 2,697 | $159K |
| Aquatic Capital Management LLC | 0.00% | New | 2,300 | $135K |
| American International Group, Inc. | 0.00% | Reduce -1.5% | 1,685 | $99K |
| KBC Group NV | 0.00% | Reduce -1.5% | 1,597 | $94K |
| Parallel Advisors, LLC | 0.00% | Add +2.9% | 1,541 | $91K |
| BI Asset Management Fondsmaeglerselskab A/S | 0.00% | New | 1,510 | $89K |
| Quantbot Technologies LP | 0.00% | Add +147.9% | 1,480 | $87K |
| Natixis | 0.00% | Reduce -98.5% | 1,339 | $79K |
| Signaturefd, LLC | 0.00% | Add +62.0% | 1,087 | $64K |
| Cwm, LLC | 0.00% | Add +403.9% | 1,038 | $61K |
| Emerald Mutual Fund Advisers Trust | 0.00% | New | 1,020 | $60K |
| Quintet Private Bank (Europe) S.A. | 0.00% | Reduce -15.2% | 638 | $44K |
| Gilliland Jeter Wealth Management LLC | 0.01% | New | 712 | $42K |
| First Horizon Advisors, Inc. | 0.00% | Add +5.8% | 711 | $42K |
| nVerses Capital, LLC | 0.10% | New | 700 | $41K |
| Pacer Advisors, Inc. | 0.00% | New | 692 | $41K |
| Jefferies Financial Group Inc. | 0.00% | Reduce -97.2% | 636 | $37K |
| Northwestern Mutual Wealth Management Co. | 0.00% | No change | 600 | $35K |
| Future Financial Wealth Managment LLC | 0.02% | New | 500 | $29K |
| Archer Investment Corp | 0.01% | No change | 500 | $29K |
| Ancora Advisors LLC | 0.00% | No change | 500 | $29K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -7.8% | 447 | $26K |
| National Bank of Canada | 0.00% | New | 600 | $25K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -89.6% | 426 | $25K |
| Avior Wealth Management, LLC | 0.00% | New | 401 | $24K |
| Allworth Financial LP | 0.00% | Reduce -6.4% | 335 | $20K |
| Lindbrook Capital, LLC | 0.00% | No change | 304 | $18K |
| Principal Securities, Inc. | 0.00% | Reduce -6.9% | 269 | $16K |
| Acadian Asset Management LLC | 0.00% | Reduce -2.3% | 258 | $15K |
| Harvest Fund Management Co., Ltd | 0.00% | New | 230 | $14K |
| GAMMA Investing LLC | 0.00% | Add +103.5% | 234 | $14K |
| AdvisorNet Financial, Inc | 0.00% | Reduce -8.0% | 230 | $14K |
| NewEdge Advisors, LLC | 0.00% | Reduce -10.7% | 226 | $13K |
| Covestor Ltd | 0.01% | Reduce -0.5% | 206 | $12K |
| Global Retirement Partners, LLC | 0.00% | Add +84.3% | 199 | $12K |
| Annis Gardner Whiting Capital Advisors, LLC | 0.00% | New | 187 | $11K |
| Quadrant Capital Group LLC | 0.00% | Add +3.5% | 180 | $11K |
| Bell Investment Advisors, Inc | 0.00% | Add +8.7% | 113 | $7K |
| Leonteq Securities AG | 0.00% | Reduce -66.4% | 111 | $7K |
| Financial Gravity Asset Management, Inc. | 0.00% | Add +1.0% | 101 | $6K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 97 | $6K |
| Farther Finance Advisors, LLC | 0.00% | Add +1.1% | 88 | $5K |
| Rakuten Securities, Inc. | 0.00% | New | 85 | $5K |
| Whittier Trust Co. of Nevada Inc. | 0.00% | Reduce -3.2% | 60 | $4K |
| New Covenant Trust Company, N.A. | 0.00% | — | 55 | $3K |
| Sachetta, LLC | 0.00% | No change | 50 | $3K |
| Parkside Financial Bank & Trust | 0.00% | No change | 44 | $3K |
| Carolinas Wealth Consulting LLC | 0.00% | Reduce -26.4% | 39 | $2K |
| Key Financial Inc | 0.00% | No change | 38 | $2K |
| Harbour Investments, Inc. | 0.00% | No change | 38 | $2K |
| TFC Financial Management, Inc. | 0.00% | New | 36 | $2K |
| Avion Wealth | 0.00% | Add +63.6% | 18 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 34 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +39.3% | 39 | $2K |
| CENTRAL TRUST Co | 0.00% | No change | 27 | $2K |
| Quent Capital, LLC | 0.00% | Add +242.9% | 24 | $1K |
| Park Place Capital Corp | 0.00% | No change | 23 | $1K |
| Spire Wealth Management | 0.00% | Add +91.7% | 23 | $1K |
| TD Private Client Wealth LLC | 0.00% | New | 21 | $1K |
| Continuum Advisory, LLC | 0.00% | New | 29 | $1K |
| Geneos Wealth Management Inc. | 0.00% | New | 18 | $1K |
| Benjamin F. Edwards & Company, Inc. | 0.00% | Reduce -89.4% | 15 | $1K |
| Smartleaf Asset Management LLC | 0.00% | New | 8 | $467 |
| Fortitude Family Office, LLC | 0.00% | No change | 6 | $353 |
| Manchester Capital Management LLC | 0.00% | No change | 3 | $177 |
| JFS Wealth Advisors, LLC | 0.00% | No change | 2 | $118 |
| AlphaQuest LLC | 0.00% | New | 1 | $59 |
| Concourse Financial Group Securities, Inc. | 0.00% | No change | 1 | $58 |
"% of holder's portfolio" is APLS's weight in each manager's 13F, not the share of Apellis Pharmaceuticals Inc. the manager owns.