InsmedINSM

13F holders, Q3 2025 (September 30)
566holders +50
125new positions
70sold out
11famous investors
$143.81avg. 13F price*

At the end of Q3 2025, 566 institutions reported holding Insmed Inc. (INSM) in their 13F filings, up 50 from Q2 2025. 125 opened new positions and 70 sold out. The largest holders were JPMorgan Chase & Co. ($3.3B), Darwin Global Management, Ltd. ($2.9B) and Vanguard Group Inc. ($2.9B). 11 famous investors held it, including Stanley Druckenmiller (8.9% of Duquesne Family Office's portfolio), Lee Ainslie (1.3% of Maverick Capital's portfolio) and David E. Shaw (0.7% of D. E. Shaw & Co.'s portfolio).

Company
Insmed Inc.
CUSIP
457669307
Latest filing quarter
Q2 2026

History

Number of 13F holders

0200400600800 Q1 2024: 288Q1 2024Q2 2024: 378Q2 2024Q3 2024: 414Q3 2024Q4 2024: 438Q4 2024Q1 2025: 441Q1 2025Q2 2025: 516Q2 2025Q3 2025: 566Q3 2025Q4 2025: 678Q4 2025Q1 2026: 675Q1 2026Q2 2026: 667Q2 2026

Total Exit/New Position Q2 2025 → Q3 2025

InstitutionsTotal Value
New Positions125$416.8M
Exits70$608.5M

All 13F filers, Q2 2025 → Q3 2025: 34,213,868 shares bought and 31,890,893 shares sold, net +2,322,975 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 566 holders

JPMorgan Chase & Co. 0.21% Add +47.4% 23,047,676 $3.3B
Darwin Global Management, Ltd. 80.54% Add +5.8% 20,457,445 $2.9B
Vanguard Group Inc. 0.04% Add +13.0% 19,935,820 $2.9B
BlackRock, Inc. 0.03% Add +11.0% 12,364,904 $1.8B
FMR LLC 0.07% Add +80.3% 9,180,963 $1.3B
Capital International Investors 0.18% Add +1.0% 7,553,853 $1.1B
T. Rowe Price Associates Inc. 0.11% Reduce -38.3% 6,931,466 $998.2M
Baker Bros. Advisors LP 7.00% Reduce -13.1% 6,703,484 $965.4M
D. E. Shaw & Co. 0.70% Add +65.3% 5,657,464 $814.7M
Artisan Partners Limited Partnership 1.02% Add +49.0% 4,937,683 $711.1M
State Street Corp. 0.02% Reduce -6.9% 3,984,354 $573.8M
Geode Capital Management, LLC 0.03% Add +12.5% 3,759,427 $541.5M
Orbis Allan Gray Ltd 2.01% Add +113.3% 3,250,868 $468.2M
RTW Investments, LP 5.47% No change 3,084,558 $444.2M
Ameriprise Financial Inc. 0.09% Reduce -8.0% 2,721,879 $392.0M
Duquesne Family Office 8.88% Add +7.5% 2,423,435 $349.0M
Millennium Management 0.28% Add +10.1% 2,336,112 $336.4M
Franklin Resources Inc. 0.08% Reduce -8.9% 2,139,725 $308.1M
Citadel Advisors 0.24% Add +34.2% 2,057,641 $296.3M
Invesco Ltd. 0.05% Add +5.7% 2,003,871 $288.6M
UBS Group AG 0.05% Add +461.0% 1,646,239 $237.1M
Bank of America Corp. 0.02% Add +30.6% 1,601,806 $230.7M
Integral Health Asset Management, LLC 16.80% No change 1,600,000 $230.4M
William Blair Investment Management, LLC 0.58% Reduce -6.6% 1,555,057 $223.9M
Qube Research & Technologies Ltd 0.31% Add +42.7% 1,544,315 $222.4M
Lord, Abbett & Co. LLC 0.65% Reduce -6.5% 1,444,656 $208.0M
Royal Bank of Canada 0.03% Add +216.8% 1,355,331 $195.2M
Adage Capital Partners Gp, L.L.C. 0.29% Reduce -56.2% 1,252,503 $180.4M
Janus Henderson Group PLC 0.08% Reduce -47.5% 1,202,783 $173.2M
Bank of New York Mellon Corp 0.03% Reduce -4.9% 1,138,901 $164.0M
Pictet Asset Management Holding SA 0.16% Reduce -26.6% 1,140,827 $163.9M
Castle Hook Partners LP 2.38% Add +141.1% 1,091,405 $157.2M
Holocene Advisors, LP 0.36% Reduce -46.3% 1,083,681 $156.1M
Northern Trust Corp. 0.02% Add +10.6% 1,072,942 $154.5M
Clearbridge Investments, LLC 0.12% Reduce -25.0% 1,068,018 $153.8M
Summit Partners Public Asset Management, LLC 4.89% Add +3.3% 1,041,845 $150.0M
Nwi Management LP 14.52% Add +41.8% 1,021,000 $147.0M
Eventide Asset Management, LLC 2.38% Reduce -16.0% 1,005,107 $144.7M
Charles Schwab Investment Management Inc. 0.02% Reduce -24.9% 975,279 $140.4M
Morgan Stanley 0.01% Reduce -7.7% 963,631 $138.8M
Hood River Capital Management LLC 1.50% Reduce -2.0% 881,403 $126.9M
Alliancebernstein L.P. 0.04% Reduce -35.3% 868,772 $125.1M
Principal Financial Group Inc. 0.06% Reduce -35.9% 864,294 $124.5M
FIL Ltd 0.10% Reduce -26.9% 851,954 $122.7M
Goldman Sachs Group Inc. 0.02% Reduce -54.2% 829,317 $119.4M
Fiera Capital Corp 0.38% Add +8.2% 809,121 $116.5M
Jane Street Group, LLC 0.13% Reduce -41.5% 791,734 $114.0M
Two Sigma Investments, LP 0.18% Add +105.3% 772,780 $111.3M
Raymond James Financial Inc. 0.04% Reduce -3.1% 759,978 $109.4M
Artia Global Partners LP 18.55% Reduce -2.7% 732,212 $105.4M
Wellington Management Group LLP 0.02% Reduce -38.1% 718,043 $103.4M
Perceptive Advisors LLC 2.96% Add +8.0% 702,130 $101.1M
Marshall Wace, LLP 0.10% Reduce -40.8% 658,647 $94.9M
Maverick Capital 1.27% Reduce -18.4% 656,539 $94.5M
Macquarie Group Ltd. 0.11% Reduce -42.5% 649,847 $93.6M
Ensign Peak Advisors, Inc 0.15% Add +13.8% 642,034 $92.5M
Jennison Associates LLC 0.05% Reduce -15.8% 602,775 $86.8M
GW&K Investment Management, LLC 0.77% Reduce -52.8% 601,803 $86.7M
Sei Investments Co. 0.09% Add +37.0% 593,885 $85.5M
Nuveen, LLC 0.02% Reduce -0.1% 588,122 $84.7M
1832 Asset Management L.P. 0.14% New 584,800 $84.2M
Wells Fargo & Company 0.02% Add +98.2% 513,849 $74.0M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.02% Reduce -26.3% 512,749 $73.8M
Bank of Nova Scotia 0.13% New 506,245 $72.9M
Alkeon Capital Management LLC 0.33% No change 500,000 $72.0M
Loomis Sayles & Co. L P 0.08% Reduce -38.0% 492,296 $70.9M
Palo Alto Investors LP 13.11% Reduce -43.1% 491,805 $70.8M
Westfield Capital Management Co. LP 0.29% Reduce -63.6% 487,927 $70.3M
Voloridge Investment Management, LLC 0.23% Add +50.7% 471,649 $67.9M
Deerfield Management Company, L.P. 1.12% Reduce -32.8% 471,000 $67.8M
Point72 Asset Management 0.15% Reduce -5.4% 464,217 $66.9M
Affinity Asset Advisors, LLC 6.22% Reduce -5.3% 450,000 $64.8M
New York State Common Retirement Fund 0.08% Add +4.2% 445,876 $64.2M
BNP Paribas Financial Markets 0.05% Reduce -42.5% 433,340 $62.4M
Cormorant Asset Management, LP 4.27% Reduce -20.4% 430,000 $61.9M
TimesSquare Capital Management, LLC 0.88% Reduce -51.3% 425,085 $61.2M
TD Asset Management Inc 0.05% Add +0.8% 398,256 $57.4M
Candriam S.C.A. 0.30% Reduce -9.4% 397,588 $57.3M
Dimensional Fund Advisors LP 0.01% Reduce -6.1% 386,671 $55.7M
Rock Springs Capital Management LP 3.25% Reduce -26.7% 385,000 $55.4M
ING Groep NV 0.29% New 373,500 $53.8M
Polar Capital Holdings Plc 0.26% Reduce -46.7% 371,887 $53.6M
Swiss National Bank 0.03% Add +6.9% 371,300 $53.5M
Victory Capital Management Inc. 0.03% Add +94.2% 354,907 $51.1M
Renaissance Technologies 0.07% Add +14.3% 352,887 $50.8M
Amundi 0.02% Add +2657.6% 317,096 $50.2M
Envestnet Asset Management Inc. 0.01% Reduce -6.3% 342,785 $49.4M
Long Focus Capital Management, LLC 2.78% Reduce -35.0% 338,000 $48.7M
Frontier Capital Management Co. LLC 0.42% Add +122.5% 328,884 $47.4M
Federated Hermes, Inc. 0.08% Add +202.8% 328,223 $47.3M
Patient Square Capital LP 12.57% Reduce -9.0% 326,400 $47.0M
First Turn Management, LLC 6.91% Reduce -14.2% 319,773 $46.1M
California Public Employees Retirement System 0.03% Add +39.9% 310,886 $44.8M
Brevan Howard Capital Management LP 0.62% Add +45.1% 294,047 $42.3M
Samlyn Capital, LLC 0.60% New 292,643 $42.1M
AQR Capital Management 0.03% Add +477.9% 287,286 $40.9M
Eagle Health Investments LP 10.27% Reduce -36.6% 271,600 $39.1M
First Trust Advisors LP 0.03% Add +407.8% 240,646 $34.7M
Aberdeen Group plc 0.05% Reduce -24.3% 234,622 $33.8M
Susquehanna International Group, LLP 0.05% Add +9.8% 233,106 $33.6M
Allspring Global Investments Holdings, LLC 0.05% Reduce -25.2% 227,629 $33.5M
Voya Investment Management LLC 0.04% Reduce -46.1% 219,839 $31.7M
Montanova Capital, LLC 0.95% Reduce -8.8% 217,783 $31.4M
Rhumbline Advisers 0.02% Add +2.2% 212,903 $30.7M
Legal & General Group Plc 0.01% Add +0.1% 208,021 $30.0M
Susquehanna Portfolio Strategies, LLC 0.47% No change 207,527 $29.9M
Silverarc Capital Management, LLC 4.31% Reduce -17.0% 206,648 $29.8M
Deutsche Bank AG 0.01% Add +1.4% 204,354 $29.4M
Novo Holdings A/S 1.86% Reduce -70.6% 200,000 $28.8M
Tang Capital Management LLC 1.11% No change 200,000 $28.8M
Nearwater Capital Markets, Ltd 0.39% New 200,000 $28.8M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.07% Reduce -34.2% 198,702 $28.6M
C WorldWide Group Holding A/S 0.44% Reduce -27.7% 196,110 $28.2M
Manufacturers Life Insurance Company, The 0.02% Reduce -14.3% 193,830 $27.9M
Nicholas Investment Partners, LP 2.28% Reduce -7.7% 180,451 $26.0M
California State Teachers Retirement System 0.03% Add +3.4% 179,402 $25.8M
Russell Investments Group, Ltd. 0.03% Reduce -29.1% 166,459 $24.0M
Caisse de depot et placement du Quebec 0.04% New 164,400 $23.7M
Comerica Bank 0.09% Reduce -30.4% 161,804 $23.3M
AXA Investment Managers S.A. 0.06% — 156,431 $22.5M
Neuberger Berman Group LLC 0.02% Add +1277.8% 150,106 $21.6M
Algert Global LLC 0.35% Add +76.7% 144,726 $20.8M
State Board of Administration of Florida Retirement System 0.03% Add +3.7% 135,020 $19.4M
State of Wisconsin Investment Board 0.04% Add +13.1% 133,365 $19.2M
Rhenman & Partners Asset Management AB 2.10% Reduce -24.8% 131,885 $19.0M
Assenagon Asset Management S.A. 0.03% Add +76.1% 129,245 $18.6M
Los Angeles Capital Management LLC 0.06% Reduce -61.5% 127,503 $18.4M
Woodline Partners LP 0.09% Reduce -49.3% 126,262 $18.2M
Barclays PLC 0.01% Reduce -39.5% 114,196 $16.4M
Jefferies Financial Group Inc. 0.15% Add +2069.3% 108,097 $15.6M
Axiom Investors LLC 0.11% Add +77.4% 107,733 $15.5M
LPL Financial LLC 0.00% Add +49.8% 106,938 $15.4M
Van Eck Associates Corp. 0.01% Reduce -10.9% 106,702 $15.4M
Sofinnova Investments, Inc. 0.92% Reduce -66.8% 104,339 $15.0M
Driehaus Capital Management LLC 0.10% Reduce -8.1% 99,301 $14.3M
Atika Capital Management LLC 1.17% New 95,000 $13.7M
Fred Alger Management, LLC 0.05% Reduce -50.4% 94,033 $13.5M
LMR Partners LLP 0.26% Add +36.1% 93,912 $13.5M
Royce & Associates LP 0.13% Add +2.6% 92,376 $13.3M
Bank of Montreal 0.01% Add +209.1% 91,766 $13.2M
EULAV Asset Management 0.30% New 90,000 $13.0M
Essex Investment Management Co. LLC 1.92% Add +31.3% 87,077 $12.5M
Man Group plc 0.02% New 85,169 $12.3M
Treasurer of the State of North Carolina 0.04% Add +0.4% 83,752 $12.1M
Police & Firemen's Retirement System of New Jersey 0.10% Add +21.5% 82,514 $11.9M
Citigroup Inc. 0.01% Reduce -7.6% 80,086 $11.5M
Rice Hall James & Associates, LLC 0.63% Reduce -8.2% 79,667 $11.5M
Trexquant Investment LP 0.11% Add +2.0% 76,753 $11.1M
American Century Companies Inc. 0.01% Reduce -59.7% 76,679 $11.0M
Aquatic Capital Management LLC 0.20% Reduce -61.8% 76,343 $11.0M
Stifel Financial Corp. 0.01% Add +29.4% 69,860 $10.1M
Creative Planning 0.01% Reduce -3.2% 69,855 $10.1M
Schroder Investment Management Group 0.01% Reduce -19.1% 70,921 $10.0M
Mutual of America Capital Management LLC 0.11% Reduce -19.4% 69,754 $10.0M
State of New Jersey Common Pension Fund D 0.04% Add +3.5% 66,324 $9.6M
Cinctive Capital Management LP 0.48% Add +101.3% 66,181 $9.5M
Allianz Asset Management GmbH 0.01% Reduce -17.8% 66,083 $9.5M
Canada Pension Plan Investment Board 0.01% Reduce -29.2% 62,013 $8.9M
Schonfeld Strategic Advisors LLC 0.06% Reduce -27.3% 60,635 $8.7M
Public Employees Retirement System of Ohio 0.03% Add +5.0% 58,191 $8.4M
Nwam LLC 0.45% Reduce -0.7% 49,538 $8.3M
Arizona State Retirement System 0.04% Add +5.9% 56,164 $8.1M
Jain Global LLC 0.11% Reduce -56.0% 55,938 $8.1M
Rafferty Asset Management, LLC 0.03% Reduce -43.8% 55,159 $7.9M
Skandinaviska Enskilda Banken AB (publ) 0.03% Add +97.1% 54,784 $7.9M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% Reduce -36.9% 54,529 $7.9M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.02% Add +5.3% 54,200 $7.8M
Connor, Clark & Lunn Investment Management Ltd. 0.02% Reduce -77.2% 51,658 $7.4M
Picton Mahoney Asset Management 0.10% Reduce -39.7% 51,603 $7.4M
Two Sigma Advisers, LP 0.01% Add +193.1% 51,300 $7.4M
Handelsbanken Fonder AB 0.02% Add +4.4% 50,181 $7.2M
Empowered Funds, LLC 0.07% New 50,000 $7.2M
HighVista Strategies LLC 1.76% Add +330.8% 49,949 $7.2M
DekaBank Deutsche Girozentrale 0.01% No change 50,000 $7.0M
Catalyst Funds Management Pty Ltd 1.05% Add +1.5% 47,900 $6.9M
Voleon Capital Management LP 0.17% Add +899.9% 47,667 $6.9M
Informed Momentum Co LLC 0.78% Reduce -19.9% 47,972 $6.8M
Erste Asset Management GmbH 0.07% No change 47,600 $6.7M
Teacher Retirement System of Texas 0.03% Reduce -4.8% 46,637 $6.7M
CANADA LIFE ASSURANCE Co 0.01% Add +1.7% 47,042 $6.7M
Polymer Capital Management (HK) LTD 0.89% Add +653.8% 44,416 $6.4M
Thornburg Investment Management Inc. 0.08% Reduce -17.3% 44,048 $6.3M
Stempoint Capital LP 1.26% Reduce -29.5% 43,419 $6.3M
Hillsdale Investment Management Inc. 0.19% Reduce -14.1% 42,700 $6.1M
Point72 (DIFC) Ltd 0.42% Add +113.4% 41,785 $6.0M
Cetera Investment Advisers 0.01% Add +30.9% 41,171 $5.9M
MML Investors Services, LLC 0.02% Reduce -16.4% 41,000 $5.9M
KLP Kapitalforvaltning As 0.02% Add +8.5% 41,000 $5.9M
Natixis Advisors, LLC 0.01% Add +11.3% 39,450 $5.7M
Truist Financial Corp. 0.01% Reduce -16.0% 39,063 $5.6M
Acuta Capital Partners, LLC 5.74% Add +4.1% 38,592 $5.6M
Baron Capital (BAMCO) 0.01% Add +4.1% 38,200 $5.5M
Quadrature Capital Ltd 0.06% Reduce -61.0% 37,735 $5.4M
Balyasny Asset Management L.P. 0.01% New 37,481 $5.4M
BI Asset Management Fondsmaeglerselskab A/S 0.05% Reduce -56.0% 37,424 $5.4M
China Universal Asset Management Co., Ltd. 0.44% Add +1.3% 37,051 $5.3M
Guggenheim Capital LLC 0.04% Reduce -10.9% 36,860 $5.3M
Orion Porfolio Solutions, LLC 0.04% Reduce -12.3% 36,693 $5.3M
Assetmark, Inc. 0.01% Add +9.9% 35,294 $5.1M
Calamos Advisors LLC 0.03% Add +53.4% 35,215 $5.1M
Legato Capital Management LLC 0.55% Reduce -3.5% 34,832 $5.0M
Pathstone Holdings, LLC 0.02% Reduce -18.1% 31,621 $4.6M
Utah Retirement Systems 0.04% Add +225.7% 30,729 $4.4M
Kennedy Capital Management LLC 0.10% Add +38.6% 30,354 $4.4M
STRS Ohio 0.02% Add +590.3% 29,454 $4.2M
Mariner, LLC 0.01% Reduce -1.7% 28,869 $4.2M
Landscape Capital Management, L.L.C. 0.26% New 28,194 $4.1M
Quantessence Capital LLC 1.28% Reduce -62.8% 28,157 $4.1M
Verition Fund Management LLC 0.02% Reduce -69.8% 28,152 $4.1M
McRae Capital Management Inc. 0.78% New 27,195 $3.9M
Xponance LLC 0.03% Add +6.3% 26,418 $3.8M
Brown Advisory Inc. 0.00% Reduce -95.5% 26,109 $3.8M
Compound Planning, Inc. 0.11% Add +2.8% 23,739 $3.4M
Osaic Holdings, Inc. 0.00% Add +159.9% 22,748 $3.2M
Baird Financial Group, Inc. 0.01% Reduce -13.0% 22,386 $3.2M
Oak Ridge Investments LLC 0.21% Reduce -35.3% 22,136 $3.2M
Wolverine Trading, LLC 0.06% Add +46.4% 22,095 $3.1M
Atria Investments, Inc 0.04% Add +27.4% 21,413 $3.1M
Cerity Partners LLC 0.01% Reduce -24.1% 21,361 $3.1M
VIRGINIA RETIREMENT SYSTEMS ET Al 0.02% Add +17.1% 21,265 $3.1M
Walleye Trading LLC 0.05% New 21,085 $3.0M
Bellevue Group AG 0.06% Reduce -75.1% 20,251 $2.9M
Fieldview Capital Management, LLC 0.48% New 20,229 $2.9M
Superstring Capital Management LP 2.81% Add +35.8% 19,786 $2.8M
Simplify Asset Management Inc. 0.06% Add +26.6% 19,664 $2.8M
Sanctuary Advisors, LLC 0.02% Add +76.1% 19,534 $2.8M
New York Life Investment Management LLC 0.02% Add +2.7% 19,177 $2.8M
Tobam 1.00% New 19,097 $2.8M
Campbell & CO Investment Adviser LLC 0.21% New 19,060 $2.7M
Public Employees Retirement Association of Colorado 0.01% Reduce -1.2% 19,020 $2.7M
West Michigan Advisors, LLC 0.61% New 17,619 $2.5M
SG Americas Securities, LLC 0.01% Add +324.4% 17,406 $2.5M
Mackenzie Financial Corp. 0.00% Add +23.8% 16,819 $2.4M
Keybank National Association 0.01% Add +76.7% 16,716 $2.4M
Group One Trading LLC 0.07% New 16,535 $2.4M
Oppenheimer Asset Management Inc. 0.03% Reduce -25.8% 15,853 $2.3M
Next Century Growth Investors LLC 0.17% New 15,849 $2.3M
Corient Private Wealth LP 0.00% Add +3.6% 15,560 $2.2M
IMC-Chicago, LLC 0.04% New 15,282 $2.2M
WCM Investment Management, LLC 0.00% Reduce -89.9% 15,500 $2.2M
Elo Mutual Pension Insurance Co 0.04% New 15,086 $2.2M
EFG Asset Management (North America) Corp. 0.28% Reduce -76.4% 14,973 $2.2M
Amalgamated Bank 0.01% Add +12.0% 14,533 $2.1M
Point72 Asia (Singapore) Pte. Ltd. 0.32% Add +162.7% 14,371 $2.1M
Point72 Hong Kong Ltd 0.09% Reduce -79.9% 14,021 $2.0M
Ikarian Capital, LLC 0.40% Reduce -91.6% 13,751 $2.0M
Orbimed Advisors LLC 0.05% No change 13,459 $1.9M
Sectoral Asset Management Inc. 1.19% Reduce -9.8% 13,425 $1.9M
Granahan Investment Management, LLC 0.08% Reduce -88.4% 13,402 $1.9M
Dana Investment Advisors, Inc. 0.06% Reduce -21.8% 13,375 $1.9M
O'shaughnessy Asset Management, LLC 0.01% Add +16.6% 13,226 $1.9M
Federation des caisses Desjardins du Quebec 0.01% Add +2544.6% 13,223 $1.9M
Groupama Asset Managment 0.03% No change 13,175 $1.9M
Main Management ETF Advisors, LLC 0.07% New 13,175 $1.9M
Boothbay Fund Management, LLC 0.05% Reduce -75.7% 12,817 $1.8M
Quantinno Capital Management LP 0.01% Add +186.0% 12,778 $1.8M
Engineers Gate Manager LP 0.02% New 12,468 $1.8M
Emerald Advisers, LLC 0.06% Reduce -6.6% 12,393 $1.8M
Emerald Mutual Fund Advisers Trust 0.09% Reduce -51.5% 12,322 $1.8M
MYDA Advisors LLC 0.52% Reduce -62.5% 12,000 $1.7M
Avidity Partners Management LP 0.38% Reduce -80.3% 11,600 $1.7M
Profund Advisors LLC 0.05% Reduce -41.9% 11,373 $1.6M
MetLife Investment Management, LLC 0.01% Add +7.4% 11,373 $1.6M
Parallax Volatility Advisers, L.P. 0.05% Reduce -41.4% 11,144 $1.6M
F/m Investments LLC 0.06% Reduce -53.0% 11,067 $1.6M
Prudential Financial Inc. 0.00% Reduce -92.9% 10,970 $1.6M
Tidal Investments LLC 0.01% Add +167.6% 10,798 $1.6M
Qsemble Capital Management, LP 0.15% New 10,711 $1.5M
Park Avenue Securities LLC 0.01% Reduce -3.7% 10,677 $1.5M
Nisa Investment Advisors, LLC 0.01% Add +374.6% 10,466 $1.5M
Draper Asset Management, LLC 0.90% Add +44.5% 10,339 $1.5M
Neo Ivy Capital Management 0.34% Reduce -43.9% 9,688 $1.4M
KBC Group NV 0.00% Add +93.3% 9,617 $1.4M
Yorktown Management & Research Co Inc 1.10% Add +64.1% 9,600 $1.4M
Vanguard Personalized Indexing Management, LLC 0.01% Add +18.2% 9,552 $1.4M
Maryland State Retirement & Pension System 0.03% Add +7.0% 9,284 $1.3M
Dark Forest Capital Management LP 0.05% New 9,242 $1.3M
Mirae Asset Global Investments Co., Ltd. 0.00% Add +21.2% 9,082 $1.3M
Rockefeller Capital Management L.P. 0.00% New 8,912 $1.3M
SummitTX Capital, L.P. 0.05% Reduce -53.9% 8,800 $1.3M
Waldron Private Wealth LLC 0.05% No change 8,800 $1.3M
Parnassus Investments, LLC 0.00% Add +10.1% 8,727 $1.3M
Swiss Life Asset Management Ltd 0.01% Add +83.8% 8,716 $1.3M
US Bancorp \de 0.00% Reduce -11.3% 8,651 $1.2M
Himension Capital (singapore) Pte. LTD. 0.08% New 8,587 $1.2M
Wealth Enhancement Advisory Services, LLC 0.00% Add +70.9% 7,598 $1.2M
Beacon Financial Advisory LLC 0.28% No change 8,480 $1.2M
Wellington Shields Capital Management, LLC 0.19% New 8,472 $1.2M
Oxford Asset Management LLP 0.39% Add +84.8% 8,308 $1.2M
S&co Inc. 0.07% No change 8,300 $1.2M
Snowden Capital Advisors LLC 0.03% Add +0.6% 7,769 $1.1M
J. Safra Sarasin Holding AG 0.02% New 7,557 $1.1M
ProShare Advisors LLC 0.00% Add +10.7% 7,530 $1.1M
J. Goldman & Co LP 0.04% Reduce -3.8% 7,371 $1.1M
Principal Securities, Inc. 0.02% Add +22.4% 7,004 $1.0M
Walleye Capital LLC 0.01% Reduce -92.2% 6,930 $998K
PNC Financial Services Group, Inc. 0.00% Reduce -41.2% 6,811 $981K
Praxis Investment Management Inc. 0.06% Add +26.3% 6,443 $928K
QRG Capital Management, Inc. 0.01% Add +15.6% 6,420 $925K
Lion Point Capital, LP 5.11% Reduce -41.3% 6,250 $900K
&partners 0.01% Add +5.8% 6,046 $871K
Gsa Capital Partners LLP 0.07% Reduce -38.1% 6,014 $866K
Financiere des Professionnels - Fonds d'investissement inc. 0.05% Add +33.4% 5,984 $862K
Y-Intercept (Hong Kong) Ltd 0.02% Reduce -97.4% 5,884 $847K
HighMark Wealth Management LLC 0.36% Reduce -4.3% 5,750 $828K
Castleark Management LLC 0.02% Add +82.5% 5,730 $825K
Captrust Financial Advisors 0.00% Add +3.6% 5,622 $810K
Vident Advisory, LLC 0.01% Reduce -2.1% 5,558 $800K
Moody Aldrich Partners LLC 0.15% Add +2.4% 5,551 $799K
Commonwealth Equity Services, LLC 0.00% Add +18.0% 5,533 $797K
Values First Advisors, Inc. 0.42% Reduce -4.3% 5,466 $787K
Intrust Bank NA 0.07% Add +4.3% 5,427 $782K
Vise Technologies, Inc. 0.03% Reduce -8.1% 5,332 $768K
Fulton Bank, N.A. 0.03% Reduce -4.4% 5,179 $746K
B. Metzler seel. Sohn & Co. AG 0.01% Reduce -51.7% 5,081 $732K
Fox Run Management, L.L.C. 0.11% New 5,012 $722K
Baader Bank Aktiengesellschaft 0.06% New 5,032 $712K
Axq Capital, LP 0.27% Add +101.2% 4,852 $699K
CIBC Asset Management Inc 0.00% No change 4,777 $688K
Private Advisor Group, LLC 0.00% Reduce -1.6% 4,731 $681K
Virtus Investment Advisers, LLC 0.19% No change 4,587 $661K
GF Fund Management Co. LTD. 0.01% Reduce -0.7% 4,548 $655K
Focus Partners Wealth 0.00% Add +0.7% 4,536 $653K
Coldstream Capital Management Inc. 0.01% Reduce -9.2% 4,520 $651K
Cannon Global Investment Management, LLC 1.64% New 4,500 $648K
Thrivent Financial for Lutherans 0.00% Reduce -47.6% 4,487 $646K
Aigen Investment Management, LP 0.10% Reduce -72.0% 4,465 $643K
Pitcairn Co. 0.05% Reduce -14.1% 4,379 $631K
Pier 88 Investment Partners LLC 0.69% Reduce -33.6% 4,300 $619K
Tema ETFs LLC 0.05% Reduce -9.8% 4,297 $619K
NEOS Investment Management LLC 0.00% Reduce -9.8% 4,297 $619K
Meeder Advisory Services, Inc. 0.03% Add +8.7% 4,212 $607K
OneDigital Investment Advisors LLC 0.01% Reduce -15.2% 4,179 $602K
Envestnet Portfolio Solutions, Inc. 0.00% Reduce -19.8% 4,164 $600K
M&T Bank Corp 0.00% Add +71.7% 4,094 $590K
Wellington Shields & Co., LLC 0.15% New 3,950 $569K
NewEdge Wealth, LLC 0.01% New 3,031 $566K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -17.1% 3,975 $566K
Capstone Investment Advisors, LLC 0.01% New 3,835 $552K
Banque Transatlantique SA 0.01% New 3,708 $533K
Shell Asset Management Co. 0.05% Reduce -58.0% 3,604 $519K
Daiwa Securities Group Inc. 0.00% Add +467.4% 3,603 $519K
Worldquant Millennium Advisors LLC 0.00% New 3,580 $516K
Mercer Global Advisors Inc. 0.00% Add +45.3% 3,522 $507K
DNB Asset Management AS 0.00% Add +64.7% 3,396 $489K
Nomura Asset Management Co. Ltd. 0.00% Add +0.0% 3,363 $484K
Hilltop Holdings Inc. 0.03% Add +17.1% 3,357 $483K
Kohlberg Kravis Roberts & Co. L.P. 0.01% No change 3,284 $473K
Northwest & Ethical Investments L.P. 0.01% Reduce -33.5% 3,260 $462K
Avior Wealth Management, LLC 0.01% Reduce -24.1% 3,153 $454K
NewEdge Advisors, LLC 0.00% New 3,139 $452K
Beirne Wealth Consulting Services, LLC 0.11% New 3,058 $440K
Natixis 0.00% Reduce -71.5% 3,036 $437K
Cambridge Investment Research Advisors, Inc. 0.00% New 3,037 $437K
Farallon Capital Management, L.L.C. 0.00% No change 3,000 $432K
Integrated Wealth Concepts LLC 0.00% Add +17.2% 2,918 $420K
Stratos Wealth Partners, LTD. 0.01% Add +31.1% 2,903 $418K
HighPoint Advisor Group LLC 0.02% Reduce -17.5% 2,852 $411K
CTC Alternative Strategies, Ltd. 0.66% New 2,850 $410K
Harvest Fund Management Co., Ltd 0.02% New 2,837 $408K
Henshaw Capital LLC 0.02% Reduce -76.1% 2,832 $408K
Headlands Technologies LLC 0.03% New 2,815 $405K
Kestra Advisory Services, LLC 0.00% Add +4.8% 2,793 $402K
B. Riley Wealth Advisors, Inc. 0.02% Reduce -3.8% 2,785 $401K
Sagespring Wealth Partners, LLC 0.01% Add +8.0% 2,729 $393K
JGP Global Gestao de Recursos Ltda. 0.23% Reduce -14.3% 2,697 $388K
HighTower Advisors, LLC 0.00% Add +24.9% 2,687 $387K
Abel Hall, LLC 0.15% Reduce -26.1% 2,558 $368K
Soleus Capital Management, L.P. 0.02% Reduce -96.5% 2,550 $367K
Vestmark Advisory Solutions, Inc. 0.01% New 2,548 $367K
Scissortail Wealth Management, LLC 0.08% No change 2,500 $360K
National Bank of Canada 0.00% Reduce -1.7% 2,481 $357K
Cwm, LLC 0.00% Add +41.8% 2,455 $354K
Leonteq Securities AG 0.02% New 2,450 $353K
Sowell Financial Services LLC 0.01% Reduce -29.4% 2,410 $347K
IFP Advisors, Inc 0.01% Reduce -0.8% 2,404 $346K
Danske Bank A/S 0.00% No change 2,400 $346K
Insigneo Advisory Services, LLC 0.02% New 2,396 $345K
Kingsview Wealth Management, LLC 0.01% Add +2.6% 2,321 $334K
Choreo, LLC 0.00% Add +2.9% 2,319 $334K
Sequoia Financial Advisors, LLC 0.00% New 2,307 $332K
United Capital Financial Advisors, LLC 0.00% Add +13.8% 2,282 $329K
Concurrent Investment Advisors, LLC 0.01% New 2,263 $326K
Cooper Financial Group 0.04% New 2,250 $324K
Debussy Capital Management LP 0.05% Reduce -30.8% 2,238 $322K
Crossmark Global Holdings, Inc. 0.00% New 2,193 $316K
Yousif Capital Management, LLC 0.00% Add +9.3% 2,188 $315K
Acadian Asset Management LLC 0.00% Add +90.9% 2,203 $315K
Regions Financial Corp. 0.00% Reduce -26.9% 2,160 $311K
Blueshift Asset Management, LLC 0.09% New 2,111 $304K
JCIC Asset Management Inc. 0.09% — 2,084 $300K
Apollon Wealth Management, LLC 0.01% New 2,050 $295K
Cravens & Co Advisors, LLC 0.20% New 2,020 $291K
Jupiter Wealth Management LLC 0.14% New 2,000 $288K
LongView Wealth Management 0.08% New 2,000 $288K
Cornerstone Wealth Management, LLC 0.02% No change 2,000 $288K
GRIMES & Co WEALTH MANAGEMENT, LLC 0.01% New 2,000 $288K
Anb Bank 0.12% Reduce -3.2% 1,985 $286K
Parallel Advisors, LLC 0.01% Add +0.9% 1,981 $285K
Global Retirement Partners, LLC 0.01% Add +128.7% 1,848 $266K
Forum Financial Management, LP 0.00% Reduce -33.4% 1,835 $264K
Citizens Financial Group Inc. 0.00% New 1,833 $264K
Brucke Financial, Inc. 0.15% New 1,384 $262K
Cigna Investments Inc. 0.04% New 1,798 $259K
Ossiam 0.00% New 1,773 $255K
Significant Wealth Partners LLC 0.12% New 1,740 $251K
Summit Trail Advisors, LLC 0.00% New 1,733 $250K
Savant Capital, LLC 0.00% New 1,728 $249K
CI Investments Inc. 0.00% Reduce -36.8% 1,722 $248K
Chung Wu Investment Group, LLC 0.21% No change 1,720 $248K
Tudor Investment Corporation 0.00% Reduce -98.7% 1,703 $245K
Quarry LP 0.06% Reduce -38.2% 1,683 $242K
Gotham Asset Management 0.00% New 1,649 $237K
RWC Asset Management LLP 0.01% Reduce -46.0% 1,648 $237K
Farther Finance Advisors, LLC 0.00% Add +228.0% 1,591 $229K
American Trust 0.02% New 1,553 $224K
Bridges Investment Management Inc. 0.00% New 1,537 $221K
Independent Financial Group, LLC 0.01% New 1,535 $221K
Lido Advisors, LLC 0.00% New 1,512 $218K
HSBC Holdings PLC 0.00% Reduce -88.3% 1,512 $217K
Knollwood Investment Advisory, LLC 0.02% New 1,501 $216K
Ethic Inc. 0.00% New 1,489 $214K
Journey Strategic Wealth LLC 0.01% New 1,488 $214K
Allegheny Financial Group 0.04% New 1,479 $213K
Everpar Advisors LLC 0.08% New 1,453 $209K
Gabelli Funds LLC 0.00% New 1,440 $207K
Bridgefront Capital, LLC 0.06% New 1,425 $205K
EntryPoint Capital, LLC 0.08% New 1,421 $205K
Laird Norton Wetherby Wealth Management, LLC 0.01% New 1,417 $204K
PharVision Advisers, LLC 0.11% New 1,404 $202K
Independent Advisor Alliance 0.01% New 1,403 $202K
Venture Visionary Partners LLC 0.01% New 1,400 $202K
Tower Research Capital LLC (TRC) 0.01% Reduce -97.0% 1,342 $193K
GAMMA Investing LLC 0.01% Add +45.9% 1,167 $168K
LRI Investments, LLC 0.01% Add +83.8% 1,070 $154K
Manchester Capital Management LLC 0.02% Add +1.6% 1,020 $147K
Rakuten Securities, Inc. 0.05% Add +19900.0% 1,000 $144K
Sterling Capital Management LLC 0.00% Reduce -1.2% 987 $142K
Bessemer Group Inc. 0.00% Add +137.5% 836 $121K
Arax Advisory Partners 0.00% Add +644.3% 789 $114K
Spire Wealth Management 0.00% Add +11.5% 777 $112K
Smartleaf Asset Management LLC 0.01% Add +106.3% 786 $111K
Steward Partners Investment Advisory, LLC 0.00% Add +12.1% 688 $99K
EverSource Wealth Advisors, LLC 0.00% Add +2.1% 678 $98K
Hilltop National Bank 0.02% Add +122.2% 620 $89K
Signaturefd, LLC 0.00% Add +14.8% 614 $88K
First Horizon Corp. 0.00% — 587 $85K
ORG Partners LLC 0.02% Add +104.6% 583 $84K
Blue Trust, Inc. 0.00% No change 564 $81K
Allworth Financial LP 0.00% Add +70.0% 527 $76K
Jones Financial Companies LLLP 0.00% Add +230.1% 548 $75K
Monetary Management Group Inc. 0.02% New 500 $72K
Johnson Financial Group, Inc. 0.00% New 466 $67K
Cullen/Frost Bankers, Inc. 0.00% Reduce -2.4% 406 $58K
Lanark Financial, Inc. 0.00% Reduce -34.0% 379 $55K
Aster Capital Management (DIFC) Ltd 0.03% Reduce -94.3% 348 $50K
Private Wealth Asset Management, LLC 0.01% No change 333 $48K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% No change 321 $46K
Rise Advisors, LLC 0.02% No change 316 $46K
Rossby Financial, LCC 0.01% Add +132.3% 302 $44K
Berbice Capital Management LLC 0.03% New 300 $43K
AlphaQuest LLC 0.00% Add +109.5% 287 $41K
Whittier Trust Co. of Nevada Inc. 0.00% Add +169.7% 240 $38K
RiverPark Advisors, LLC 0.03% New 261 $38K
Huntington National Bank 0.00% Reduce -60.2% 242 $35K
UMB Bank, n.a. 0.00% Add +23.9% 233 $34K
MassMutual Private Wealth & Trust, FSB 0.00% Add +59.6% 217 $31K
SBI Securities Co., Ltd. 0.00% Add +404.9% 207 $30K
Transamerica Financial Advisors, LLC 0.00% New 202 $29K
Stone House Investment Management, LLC 0.00% New 200 $29K
Versant Capital Management, Inc 0.00% Reduce -10.1% 187 $27K
CIBC Private Wealth Group LLC 0.00% Add +42.1% 179 $26K
Covestor Ltd 0.01% Add +1.8% 167 $24K
iA Global Asset Management Inc. 0.00% Reduce -23.9% 166 $24K
Ameriflex Group, Inc. 0.01% New 164 $24K
B Group, Inc. 0.02% Reduce -99.9% 158 $23K
Advisory Services Network, LLC 0.00% New 156 $22K
Contravisory Investment Management, Inc. 0.00% Reduce -12.1% 146 $21K
MAI Capital Management 0.00% Add +400.0% 120 $17K
WPG Advisers, LLC 0.01% Reduce -8.5% 119 $17K
Northwestern Mutual Wealth Management Co. 0.00% Add +936.4% 114 $16K
Larson Financial Group LLC 0.00% Add +980.0% 108 $16K
AdvisorNet Financial, Inc 0.00% Add +33.8% 107 $15K
Trust Co. of Vermont 0.00% No change 95 $14K
Truvestments Capital LLC 0.00% No change 84 $12K
Groupe la Francaise 0.00% New 100 $12K
Caption Management, LLC 0.00% Reduce -100.0% 81 $12K
Sunbelt Securities, Inc. 0.00% New 74 $11K
Private Trust Co. NA 0.00% Reduce -43.4% 73 $11K
Geneos Wealth Management Inc. 0.00% Reduce -34.2% 73 $11K
Wealthspire Advisors, LLC 0.00% New 58 $8K
Fourth Dimension Wealth, LLC 0.00% Reduce -97.6% 57 $8K
Salomon & Ludwin, LLC 0.00% New 52 $8K
T. Rowe Price Investment Management, Inc. 0.00% New 54 $8K
Motco 0.00% New 54 $8K
Cornerstone Planning Group LLC 0.00% No change 38 $7K
Valley National Advisers Inc. 0.00% New 50 $7K
Cape Investment Advisory, Inc. 0.01% No change 47 $7K
Meeder Asset Management Inc. 0.00% Reduce -30.2% 44 $6K
Hemington Wealth Management 0.00% Add +7.0% 46 $6K
Marshall & Sterling Wealth Advisors Inc. 0.00% New 41 $6K
Retirement Wealth Solutions LLC 0.00% New 38 $5K
Fairscale Capital, LLC 0.00% No change 37 $5K
Aventura Private Wealth, LLC 0.00% No change 36 $5K
Activest Wealth Management 0.00% New 36 $5K
Bell Investment Advisors, Inc 0.00% Add +29.6% 35 $5K
Avion Wealth 0.00% Add +5.6% 38 $5K
Wolff Wiese Magana LLC 0.00% No change 34 $5K
Clearstead Advisors, LLC 0.00% Reduce -94.6% 33 $5K
Washington Trust Advisors, Inc. 0.00% Reduce -69.4% 33 $5K
Root Financial Partners, LLC 0.00% New 32 $5K
JFS Wealth Advisors, LLC 0.00% Add +3.3% 31 $4K
JPL Wealth Management, LLC 0.00% New 30 $4K
Evermay Wealth Management LLC 0.00% Add +50.0% 30 $4K
Webster Bank, N. A. 0.00% No change 30 $4K
TD Private Client Wealth LLC 0.00% No change 30 $4K
Clearstead Trust, LLC 0.00% New 29 $4K
Colonial Trust Co / SC 0.00% Add +52.6% 29 $4K
Marquette Asset Management, LLC 0.00% New 28 $4K
Cromwell Holdings LLC 0.00% No change 27 $4K
Quent Capital, LLC 0.00% New 26 $4K
Sachetta, LLC 0.00% New 25 $4K
Harbour Investments, Inc. 0.00% Add +400.0% 25 $4K
Park Place Capital Corp 0.00% No change 23 $3K
Sound Income Strategies, LLC 0.00% New 20 $3K
Montag A & Associates Inc. 0.00% Reduce -96.5% 18 $3K
Bare Financial Services, Inc 0.00% Add +28.6% 18 $3K
N.E.W. Advisory Services LLC 0.00% No change 17 $2K
Parkside Financial Bank & Trust 0.00% Reduce -34.8% 15 $2K
Roxbury Financial LLC 0.00% No change 15 $2K
Fortitude Family Office, LLC 0.00% Add +50.0% 15 $2K
True Wealth Design, LLC 0.00% Add +650.0% 15 $2K
Albion Financial Group 0.00% New 13 $2K
Bellevue Asset Management, LLC 0.00% Reduce -68.3% 13 $2K
Quadrant Capital Group LLC 0.00% New 12 $2K
Essential Partners LLC 0.00% Add +500.0% 12 $2K
Tortoise Investment Management, LLC 0.00% Add +120.0% 11 $2K
Moisand Fitzgerald Tamayo, LLC 0.00% No change 10 $1K
Physician Wealth Advisors, Inc. 0.00% Reduce -52.4% 10 $1K
MV Capital Management, Inc. 0.00% Add +150.0% 10 $1K
S&T Bank 0.00% New 10 $1K
Hughes Financial Services, LLC 0.00% No change 7 $1K
Principia Wealth Advisory, LLC 0.00% Add +166.7% 8 $1K
SouthState Bank Corp 0.00% No change 7 $1K
Cloud Capital Management, LLC 0.00% New 11 $1K
Fifth Third Bancorp 0.00% New 6 $864
DiNuzzo Private Wealth, Inc. 0.00% No change 6 $817
American Capital Advisory, LLC 0.00% No change 5 $721
Breakwater Investment Management 0.00% New 5 $721
Creative Financial Designs Inc. 0.00% New 5 $720
North Star Investment Management Corp. 0.00% New 5 $720
Plante Moran Financial Advisors, LLC 0.00% New 5 $720
Rothschild Investment LLC 0.00% New 4 $576
J.Safra Asset Management Corp 0.00% New 4 $576
Bogart Wealth, LLC 0.00% New 4 $576
SJS Investment Consulting Inc. 0.00% No change 3 $433
Quaker Wealth Management, LLC 0.00% New 2 $289
Davis Capital Management 0.00% — 2 $288
Bay Harbor Wealth Management, LLC 0.00% New 2 $288
High Note Wealth, LLC 0.00% No change 2 $288
Dogwood Wealth Management LLC 0.00% New 2 $288
HFM Investment Advisors, LLC 0.00% New 2 $288
Country Trust Bank 0.00% New 2 $288
Seneschal Advisors, LLC 0.00% New 1 $145
Rialto Wealth Management, LLC 0.00% New 1 $145
Concord Wealth Partners 0.00% No change 1 $144

"% of holder's portfolio" is INSM's weight in each manager's 13F, not the share of Insmed Inc. the manager owns.