Alnylam PharmaceuticalsALNY

13F holders, Q1 2024 (March 31)
498holders
6famous investors
$149.56avg. 13F price*

At the end of Q1 2024, 498 institutions reported holding Alnylam Pharmaceuticals Inc. (ALNY) in their 13F filings. The largest holders were Capital World Investors ($1.9B), Vanguard Group Inc. ($1.8B) and FMR LLC ($1.5B). 6 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Alnylam Pharmaceuticals Inc.
Sector
Health Care
CUSIP
02043Q107
Latest filing quarter
Q2 2026

History

Number of 13F holders

02004006008001,000 Q1 2024: 498Q1 2024Q2 2024: 523Q2 2024Q3 2024: 568Q3 2024Q4 2024: 594Q4 2024Q1 2025: 626Q1 2025Q2 2025: 654Q2 2025Q3 2025: 823Q3 2025Q4 2025: 852Q4 2025Q1 2026: 793Q1 2026Q2 2026: 793Q2 2026

Total Exit/New Position Q1 2024

InstitutionsTotal Value
New Positions66$348.3M
Exits64$410.6M

Ownership 498 holders

Capital World Investors 0.32% Reduce -20.9% 12,789,236 $1.9B
Vanguard Group Inc. 0.04% Add +0.4% 11,994,261 $1.8B
FMR LLC 0.10% Reduce -3.3% 9,967,996 $1.5B
BlackRock Inc. 0.03% Add +5.9% 9,025,007 $1.3B
Wellington Management Group LLP 0.19% Reduce -0.1% 7,209,005 $1.1B
Baillie Gifford & Co. 0.77% Reduce -4.9% 6,623,577 $989.9M
Dodge & Cox 0.33% Add +3.7% 3,811,480 $569.6M
T. Rowe Price Associates Inc. 0.07% Add +5.8% 3,685,753 $550.8M
Capital International Investors 0.11% Add +1.8% 3,651,217 $545.7M
State Street Corp. 0.02% Add +2.3% 3,191,373 $477.0M
Capital Research Global Investors 0.11% Add +7.3% 3,144,987 $470.0M
T. Rowe Price Investment Management, Inc. 0.26% Reduce -16.1% 2,872,904 $429.4M
Norges Bank 0.05% Add +12.4% 2,292,654 $342.6M
Geode Capital Management, LLC 0.03% Add +3.9% 2,001,718 $298.7M
JPMorgan Chase & Co. 0.02% Reduce -42.0% 1,748,189 $261.3M
American Century Companies Inc. 0.13% Add +231.1% 1,373,654 $205.3M
Pictet Asset Management Holding SA 0.16% Add +8.6% 961,504 $144.6M
Bellevue Group AG 2.09% Add +3.7% 918,284 $137.2M
Deep Track Capital, LP 3.58% New 832,310 $124.4M
Bank of New York Mellon Corp 0.02% Reduce -4.6% 798,445 $119.3M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.04% Add +2.4% 758,650 $113.4M
Legal & General Group Plc 0.03% Reduce -1.0% 750,602 $112.2M
Northern Trust Corp. 0.02% Reduce -3.3% 739,584 $110.5M
Amundi 0.05% Add +4.8% 746,064 $108.3M
Morgan Stanley 0.01% Reduce -16.3% 675,281 $100.9M
Loomis Sayles & Co. L P 0.12% Reduce -4.4% 581,851 $87.0M
Squarepoint Ops LLC 0.36% Add +72.8% 580,441 $86.7M
Nuveen Asset Management, LLC 0.02% Reduce -5.8% 511,978 $76.5M
Deutsche Bank AG 0.04% Add +9.7% 507,077 $75.8M
Bank of America Corp. 0.01% Add +53.3% 484,893 $72.5M
TD Asset Management Inc 0.06% Reduce -0.8% 462,348 $69.1M
Charles Schwab Investment Management Inc. 0.02% Add +2.1% 447,560 $66.9M
Gilder Gagnon Howe & Co. LLC 0.76% Reduce -31.0% 405,173 $60.6M
Swiss National Bank 0.04% Reduce -3.8% 375,900 $56.2M
Royal Bank of Canada 0.01% Add +45.1% 374,424 $56.0M
Casdin Capital, LLC 3.98% Add +83.6% 358,000 $53.5M
Vestal Point Capital, LP 4.33% Add +900.0% 350,000 $52.3M
Manufacturers Life Insurance Company, The 0.05% Reduce -1.1% 337,025 $50.4M
Royal London Asset Management Ltd. 0.12% Add +5.8% 326,869 $48.9M
Candriam S.C.A. 0.31% Add +26.6% 316,898 $47.4M
Mitsubishi UFJ Trust & Banking Corp 0.11% Reduce -10.7% 311,852 $46.6M
Avoro Capital Advisors LLC 0.52% Reduce -73.0% 300,000 $44.8M
Sumitomo Mitsui Trust Group, Inc. 0.03% Reduce -1.4% 290,996 $43.5M
Balyasny Asset Management L.P. 0.11% New 287,627 $43.0M
Corient Private Wealth LP 0.07% Reduce -0.0% 274,607 $41.0M
Canada Pension Plan Investment Board 0.04% Add +12.7% 273,790 $40.9M
Eagle Asset Management Inc. 0.20% Reduce -1.8% 258,248 $39.6M
Goldman Sachs Group Inc. 0.01% Reduce -10.8% 260,019 $38.9M
Dimensional Fund Advisors LP 0.01% Reduce -4.4% 255,179 $38.1M
Rock Springs Capital Management LP 0.93% Add +3.8% 244,000 $36.5M
Avidity Partners Management LP 1.29% New 243,000 $36.3M
Franklin Resources Inc. 0.01% Add +57.4% 237,524 $35.5M
Schonfeld Strategic Advisors LLC 0.28% Add +11963.8% 235,606 $35.2M
Polar Capital Holdings Plc 0.19% Add +27.0% 235,000 $35.1M
Aberdeen Group plc 0.06% Reduce -5.8% 219,275 $32.8M
First Trust Advisors LP 0.03% Reduce -29.1% 217,373 $32.5M
California Public Employees Retirement System 0.02% Add +19.5% 214,330 $32.0M
Man Group plc 0.09% Add +390.2% 210,235 $31.4M
Wells Fargo & Company 0.01% Reduce -10.1% 206,364 $30.8M
Point72 Asset Management 0.09% Add +139.9% 206,255 $30.8M
ANTIPODES PARTNERS Ltd 0.97% Add +8.7% 205,579 $30.7M
Millennium Management 0.03% Add +453.6% 202,278 $30.2M
Ameriprise Financial Inc. 0.01% Reduce -48.4% 194,725 $29.1M
Barclays PLC 0.01% Add +36.6% 193,972 $29.0M
California State Teachers Retirement System 0.04% Reduce -0.1% 191,418 $28.6M
Two Sigma Advisers, LP 0.07% New 189,600 $28.3M
National Pension Service 0.03% Add +11.0% 186,183 $27.8M
State Board of Administration of Florida Retirement System 0.06% Add +0.8% 137,022 $27.4M
Palo Alto Investors LP 3.08% Add +18.3% 182,766 $27.3M
ADAR1 Capital Management, LLC 7.35% Add +1796.3% 180,145 $26.9M
Janus Henderson Group PLC 0.01% Reduce -35.6% 178,954 $26.7M
CIBC Private Wealth Group LLC 0.05% Add +0.3% 174,249 $26.7M
Invesco Ltd. 0.01% Add +0.8% 178,313 $26.6M
Rhumbline Advisers 0.02% Add +0.5% 173,689 $26.0M
Jane Street Group, LLC 0.03% Add +68.4% 163,938 $24.5M
Citigroup Inc. 0.02% Add +107.0% 150,690 $22.5M
Federated Hermes, Inc. 0.05% Add +8.3% 148,504 $22.2M
AQR Capital Management 0.04% Add +906.7% 141,137 $21.1M
Credit Suisse AG/ 0.02% Reduce -26.5% 129,346 $19.3M
Jacobs Levy Equity Management, Inc. 0.08% New 126,367 $18.9M
HighTower Advisors, LLC 0.03% Add +1.5% 126,080 $18.8M
UBS Group AG 0.01% Add +37.6% 124,463 $18.6M
Hudson Bay Capital Management LP 0.18% Add +48.5% 122,500 $18.3M
Novo Holdings A/S 1.22% No change 118,383 $17.7M
DekaBank Deutsche Girozentrale 0.03% Reduce -18.0% 113,042 $17.3M
Caption Management, LLC 1.88% Add +429.8% 114,122 $17.1M
Qube Research & Technologies Ltd 0.03% Add +500.3% 110,759 $16.6M
National Bank of Canada 0.03% Add +21032.5% 108,410 $16.3M
AXA S.A. 0.05% Reduce -35.6% 107,636 $16.1M
Bank of Montreal 0.01% Add +156.5% 102,508 $15.9M
D. E. Shaw & Co. 0.02% Add +8.2% 103,387 $15.5M
Sofinnova Investments, Inc. 0.91% New 103,036 $15.4M
Two Sigma Investments, LP 0.04% New 102,512 $15.3M
BNP Paribas Financial Markets 0.02% Add +22.7% 101,446 $15.2M
Trexquant Investment LP 0.29% Add +88.7% 96,975 $14.5M
Skandinaviska Enskilda Banken AB (publ) 0.07% Add +1.4% 94,553 $14.1M
New York State Common Retirement Fund 0.02% Reduce -16.2% 93,766 $14.0M
Capital International, Inc. 0.19% Reduce -6.6% 93,376 $14.0M
Neuberger Berman Group LLC 0.01% Add +27.5% 91,350 $13.7M
Cubist Systematic Strategies, LLC 0.15% Add +400.9% 90,234 $13.5M
Schroder Investment Management Group 0.02% Add +99.9% 88,902 $13.3M
Susquehanna Fundamental Investments, LLC 0.61% New 88,067 $13.2M
Treasurer of the State of North Carolina 0.06% Add +0.8% 87,387 $13.1M
Eventide Asset Management, LLC 0.20% No change 87,000 $13.0M
Ensign Peak Advisors, Inc 0.02% Reduce -6.7% 81,770 $12.2M
Susquehanna International Group, LLP 0.02% Add +214.0% 81,662 $12.2M
Nomura Asset Management Co. Ltd. 0.04% Add +15.6% 79,743 $11.9M
Handelsbanken Fonder AB 0.05% Add +0.3% 75,106 $11.2M
Mirae Asset Global Investments Co., Ltd. 0.02% Add +63.5% 62,415 $11.2M
HSBC Holdings PLC 0.01% Add +67.7% 74,131 $11.1M
State of New Jersey Common Pension Fund D 0.03% No change 73,259 $10.9M
Capital International Sarl 0.36% Reduce -16.3% 73,109 $10.9M
LMR Partners LLP 0.38% Add +153.1% 71,371 $10.7M
Voya Investment Management LLC 0.01% Reduce -16.2% 70,497 $10.5M
Danske Bank A/S 0.03% — 69,491 $10.4M
Tobam 0.93% Reduce -24.1% 69,062 $10.3M
Mitsubishi UFJ Asset Management Co., Ltd. 0.01% Add +22.5% 68,790 $10.3M
State of Wisconsin Investment Board 0.03% Reduce -65.7% 68,714 $10.3M
Forsta Ap-Fonden 0.09% Add +199.6% 68,300 $10.2M
Asset Management One Co., Ltd. 0.04% Reduce -2.0% 67,919 $10.2M
Capital International Ltd. 0.47% Reduce -26.2% 65,224 $9.7M
Edmond DE Rothschild Holding S.A. 0.16% Add +311.7% 65,050 $9.7M
APG Asset Management N.V. 0.02% Reduce -27.7% 67,405 $9.3M
U.S. Capital Wealth Advisors, LLC 0.36% No change 61,500 $9.2M
Rafferty Asset Management, LLC 0.03% Add +15.9% 61,206 $9.1M
Assenagon Asset Management S.A. 0.02% Add +326.0% 60,342 $9.0M
Worldquant Millennium Advisors LLC 0.11% Reduce -1.5% 60,073 $9.0M
Ghost Tree Capital, LLC 2.88% Add +118.2% 60,000 $9.0M
Russell Investments Group, Ltd. 0.01% Add +88.9% 58,739 $8.9M
Van Eck Associates Corp. 0.01% Reduce -5.4% 57,923 $8.7M
Macquarie Group Ltd. 0.01% Add +18.9% 55,907 $8.4M
Capital Group Private Client Services, Inc. 0.08% Add +9.4% 54,421 $8.1M
Alliancebernstein L.P. 0.00% Reduce -89.6% 54,176 $8.1M
Bridger Management, LLC 3.57% Add +179.7% 52,922 $7.9M
Public Employees Retirement System of Ohio 0.03% Reduce -7.0% 51,548 $7.7M
Ikarian Capital, LLC 2.10% New 51,541 $7.7M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.03% Add +10.9% 50,014 $7.5M
Integral Health Asset Management, LLC 0.73% Add +11.1% 50,000 $7.5M
Eagle Health Investments LP 1.38% Reduce -64.6% 48,356 $7.2M
CANADA LIFE ASSURANCE Co 0.01% Add +3.9% 47,545 $7.1M
Resona Asset Management Co.,Ltd. 0.04% — 46,941 $7.0M
Walleye Capital LLC 0.08% Add +88.8% 46,858 $7.0M
Brown Advisory Inc. 0.01% Add +17.4% 45,486 $6.8M
Rhenman & Partners Asset Management AB 0.60% Add +12.8% 42,300 $6.3M
HRT Financial LP 0.04% New 41,927 $6.3M
Citadel Advisors 0.01% Reduce -40.0% 39,984 $6.0M
Mediolanum International Funds Ltd 0.10% — 38,556 $6.0M
Victory Capital Management Inc. 0.01% Reduce -13.8% 39,404 $5.9M
Korea Investment CORP 0.01% Add +18.3% 39,163 $5.9M
SG Americas Securities, LLC 0.03% Add +5772.0% 38,755 $5.8M
Parnassus Investments, LLC 0.01% No change 38,748 $5.8M
APG Asset Management US Inc. 0.03% Add +46.6% 35,910 $5.5M
China Universal Asset Management Co., Ltd. 0.68% Add +36.9% 35,822 $5.4M
Rosenblum Silverman Sutton S F Inc. 1.50% Reduce -1.3% 35,470 $5.3M
USS Investment Management Ltd 0.04% Add +11.7% 35,414 $5.3M
Arizona State Retirement System 0.04% Add +0.5% 34,517 $5.2M
Teachers Retirement System of the State of Kentucky 0.04% Add +8.1% 33,213 $5.0M
Banque Pictet & Cie SA 0.05% Add +44.6% 33,005 $4.9M
Montanova Capital, LLC 0.21% Add +231.2% 32,660 $4.9M
Capital Fund Management S.A. 0.06% New 30,367 $4.5M
Sei Investments Co. 0.01% Add +12.8% 29,603 $4.4M
Erste Asset Management GmbH 0.06% No change 28,510 $4.4M
Robeco Institutional Asset Management B.V. 0.01% Add +19.5% 28,840 $4.3M
Teacher Retirement System of Texas 0.03% Reduce -2.3% 28,533 $4.3M
Sector Gamma As 1.16% Reduce -14.1% 27,583 $4.1M
Envestnet Asset Management Inc. 0.00% Add +0.6% 27,435 $4.1M
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund 0.05% Reduce -1.8% 27,415 $4.1M
Burney Co./ 0.15% Add +371.9% 27,059 $4.0M
Illinois Municipal Retirement Fund 0.06% New 26,375 $3.9M
Seven Eight Capital, LP 0.40% Add +392.8% 25,809 $3.9M
IFM Investors Pty Ltd 0.04% Add +3.1% 25,651 $3.8M
Walleye Trading LLC 0.06% Add +11.8% 25,172 $3.8M
STRS Ohio 0.01% No change 25,000 $3.7M
DNB Asset Management AS 0.02% Reduce -45.9% 24,993 $3.7M
Caisse de depot et placement du Quebec 0.01% Add +26.5% 24,795 $3.7M
Engineers Gate Manager LP 0.10% Add +41.8% 24,723 $3.7M
Weiss Asset Management LP 0.22% Add +1970.1% 24,676 $3.7M
HAP Trading, LLC 1.10% New 23,798 $3.6M
Edgestream Partners, L.P. 0.17% Add +193.4% 23,355 $3.5M
Polar Asset Management Partners Inc. 0.12% New 22,600 $3.4M
Aquatic Capital Management LLC 0.11% Add +4.3% 21,800 $3.3M
Groupama Asset Managment 0.06% Reduce -87.0% 2,256 $3.3M
Utah Retirement Systems 0.04% Add +0.5% 21,525 $3.2M
Federation des caisses Desjardins du Quebec 0.02% Add +4.0% 16,685 $3.2M
Guggenheim Capital LLC 0.02% Add +19.2% 21,162 $3.2M
Privium Fund Management B.V. 0.91% Reduce -3.7% 20,893 $3.1M
Swedbank AB 0.00% Reduce -90.7% 20,639 $3.1M
EFG Asset Management (North America) Corp. 0.51% Reduce -15.8% 19,946 $3.0M
Tredje AP-fonden 0.03% No change 19,791 $3.0M
Xponance LLC 0.03% Add +39.8% 19,698 $2.9M
Principal Financial Group Inc. 0.00% Reduce -1.4% 19,356 $2.9M
Gateway Investment Advisers LLC 0.03% Add +0.0% 19,037 $2.8M
ExodusPoint Capital Management, LP 0.03% New 18,658 $2.8M
Mackenzie Financial Corp. 0.00% Reduce -8.9% 18,515 $2.8M
Storebrand Asset Management As 0.01% Reduce -48.4% 18,506 $2.8M
Sectoral Asset Management Inc. 1.08% Reduce -18.5% 18,460 $2.8M
Jump Financial, LLC 0.07% Add +140.7% 17,554 $2.6M
LPL Financial LLC 0.00% Add +1.5% 16,974 $2.5M
Capital Group Investment Management Pte. LTD. 0.43% Reduce -50.1% 16,173 $2.4M
Portman Square Capital LLP 2.46% Add +168.7% 16,023 $2.4M
Point72 Hong Kong Ltd 0.12% New 15,971 $2.4M
Nissay Asset Management Corp. /Japan 0.02% Add +2.1% 15,577 $2.3M
Twin Tree Management, LP 0.05% New 15,510 $2.3M
Connor, Clark & Lunn Investment Management Ltd. 0.01% New 15,443 $2.3M
Raymond James & Associates 0.00% Add +6.2% 15,168 $2.3M
KBC Group NV 0.01% Add +8.5% 15,096 $2.3M
Boothbay Fund Management, LLC 0.07% New 15,016 $2.2M
BRITISH COLUMBIA INVESTMENT MANAGEMENT Corp 0.02% Add +4.2% 14,983 $2.2M
AIA Group Ltd 0.07% No change 14,644 $2.2M
Public Employees Retirement Association of Colorado 0.01% Reduce -3.6% 13,875 $2.1M
Empowered Funds, LLC 0.04% Add +3.9% 13,849 $2.1M
Silvant Capital Management LLC 0.10% No change 13,661 $2.0M
Bank of Nova Scotia 0.00% Add +121.8% 13,363 $2.0M
Pinebridge Investments, L.P. 0.02% Add +31.1% 13,352 $2.0M
Comerica Bank 0.01% Reduce -2.7% 13,003 $1.9M
Toronto Dominion Bank 0.00% Reduce -73.6% 12,986 $1.9M
PNC Financial Services Group, Inc. 0.00% Reduce -7.1% 12,187 $1.8M
Allianz Asset Management GmbH 0.00% Reduce -16.5% 11,514 $1.7M
Elo Mutual Pension Insurance Co 0.04% Add +5.1% 11,467 $1.7M
NEOS Investment Management LLC 0.11% Add +280.4% 11,369 $1.7M
Duality Advisers, LP 0.17% Reduce -34.6% 11,197 $1.7M
Daiwa Securities Group Inc. 0.01% Add +1.1% 10,921 $1.6M
EFG Asset Management (Americas) Corp. 0.50% Reduce -33.0% 10,886 $1.6M
Intech Investment Management LLC 0.02% Add +44.3% 10,885 $1.6M
Rockefeller Capital Management L.P. 0.00% Reduce -3.2% 10,715 $1.6M
Campbell & CO Investment Adviser LLC 0.14% Reduce -54.6% 10,614 $1.6M
Cullen/Frost Bankers, Inc. 0.02% Add +0.1% 10,562 $1.6M
Point72 (DIFC) Ltd 0.12% — 10,363 $1.5M
FIL Ltd 0.00% Reduce -86.5% 10,355 $1.5M
Gulf International Bank (UK) Ltd 0.04% No change 10,328 $1.5M
Tidal Investments LLC 0.03% Add +292.3% 10,281 $1.5M
Maryland State Retirement & Pension System 0.03% Add +4.1% 9,836 $1.4M
Sumitomo Mitsui DS Asset Management Company, Ltd 0.02% Reduce -0.3% 9,495 $1.4M
Profund Advisors LLC 0.05% Add +11.3% 9,270 $1.4M
Nordea Investment Management AB 0.00% Add +3.3% 8,980 $1.4M
ProShare Advisors LLC 0.00% Add +10.1% 8,827 $1.3M
Vontobel Holding Ltd. 0.01% Reduce -2.7% 8,691 $1.3M
Stifel Financial Corp. 0.00% Reduce -28.5% 8,340 $1.2M
Graham Capital Management, L.P. 0.07% New 8,263 $1.2M
PEAK6 Investments LLC 0.06% Add +68.7% 8,197 $1.2M
Nisa Investment Advisors, LLC 0.01% No change 8,155 $1.2M
Wealthfront Advisers LLC 0.00% Reduce -30.2% 8,090 $1.2M
Amalgamated Bank 0.01% Reduce -29.1% 8,053 $1.2M
Ategra Capital Management, LLC 0.55% No change 7,990 $1.2M
Values First Advisors, Inc. 0.68% Add +10.8% 7,738 $1.2M
Employees Retirement System of Texas 0.01% Add +105.2% 7,717 $1.2M
Assetmark, Inc. 0.00% Add +9.7% 7,581 $1.1M
Panagora Asset Management Inc. 0.01% No change 7,457 $1.1M
Cinctive Capital Management LP 0.05% New 6,984 $1.0M
Prelude Capital Management, LLC 0.07% Add +318.5% 6,931 $1.0M
Mariner, LLC 0.00% Reduce -3.0% 6,894 $1.0M
Bokf, NA 0.02% Add +23.9% 6,712 $1.0M
SteelPeak Wealth, LLC 0.05% Add +147.7% 6,860 $1.0M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Reduce -94.7% 6,630 $991K
MetLife Investment Management, LLC 0.01% Add +1.6% 6,606 $987K
US Bancorp \de 0.00% Reduce -9.5% 6,560 $980K
M&T Bank Corp 0.00% Reduce -5.4% 6,426 $960K
Ostrum Asset Management 0.07% No change 6,189 $925K
Vanguard Personalized Indexing Management, LLC 0.02% Reduce -4.8% 6,086 $910K
S&co Inc. 0.06% New 5,750 $859K
Commonwealth Equity Services, LLC 0.00% Add +32.3% 5,594 $836K
Cibc World Markets Corp. 0.01% Add +47.6% 5,138 $768K
Alpha DNA Investment Management LLC 0.42% Add +8.7% 5,129 $767K
Beacon Investment Advisory Services, Inc. 0.03% Reduce -8.0% 5,018 $750K
Quattro Financial Advisors LLC 0.21% Add +2517.8% 5,000 $747K
Creative Planning 0.00% Reduce -2.9% 4,924 $736K
Shell Asset Management Co. 0.03% Reduce -21.8% 2,973 $722K
XTX Topco Ltd 0.10% New 4,805 $718K
Aviva PLC 0.00% Reduce -39.7% 4,778 $714K
Commerce Bank 0.00% Reduce -0.6% 4,656 $696K
Plato Investment Management Ltd 0.07% Add +2666.3% 4,509 $674K
Gilbert & Cook, Inc. 0.09% Add +0.9% 4,485 $670K
Verition Fund Management LLC 0.01% New 4,396 $657K
Brandywine Managers, LLC 0.64% No change 4,348 $650K
Stoneridge Investment Partners LLC 0.24% New 4,200 $628K
MML Investors Services, LLC 0.00% Add +5.5% 4,169 $623K
Atom Investors LP 0.08% New 4,137 $618K
Advisors Asset Management, Inc. 0.01% Add +194.0% 4,037 $603K
Teza Capital Management LLC 0.08% Reduce -64.8% 4,026 $602K
CIBC Asset Management Inc 0.00% Add +0.2% 4,022 $601K
Achmea Investment Management B.V. 0.01% No change 4,014 $599K
J.P. Marvel Investment Advisors, LLC 0.10% No change 4,000 $598K
Howland Capital Management LLC 0.03% No change 4,000 $598K
First Hawaiian Bank 0.02% No change 4,000 $598K
Clearstead Trust, LLC 0.16% No change 3,981 $595K
Ethic Inc. 0.01% Reduce -0.8% 3,976 $594K
B. Metzler seel. Sohn & Co. AG 0.01% Add +5.1% 3,918 $586K
CI Investments Inc. 0.00% Add +65.5% 3,891 $582K
Prudential Financial Inc. 0.00% Reduce -7.3% 3,861 $577K
Pathstone Holdings, LLC 0.00% Add +33.8% 3,858 $577K
Tokio Marine Asset Management Co. Ltd. 0.03% Add +7.7% 3,849 $575K
Exchange Traded Concepts, LLC 0.01% Reduce -30.0% 3,788 $566K
BI Asset Management Fondsmaeglerselskab A/S 0.01% Reduce -1.2% 3,724 $557K
Orion Capital Management LLC 0.29% No change 3,675 $549K
Captrust Financial Advisors 0.00% Reduce -21.1% 3,639 $544K
Lazard Asset Management LLC 0.00% Reduce -81.5% 3,607 $538K
Cetera Investment Advisers 0.00% Add +204.1% 3,558 $532K
Sanders Morris Harris LLC 0.10% No change 3,500 $523K
Souders Financial Advisors 0.08% Add +17.9% 3,476 $519K
Quantitative Investment Management, LLC 0.03% New 3,469 $518K
Nixon Peabody Trust Co. 0.05% No change 3,300 $493K
Hall Laurie J Trustee 0.17% No change 3,250 $486K
Paloma Partners Management Co 0.10% New 3,250 $486K
Regal Investment Advisors LLC 0.03% Add +8.5% 3,216 $481K
Cerity Partners LLC 0.00% New 3,192 $477K
GraniteShares Advisors LLC 0.25% Add +13.9% 3,177 $475K
World Equity Group, Inc. 0.10% Add +4.7% 3,155 $472K
Headlands Technologies LLC 0.11% New 3,150 $471K
Raymond James Financial Services Advisors, Inc. 0.00% Add +35.3% 3,107 $464K
Corton Capital Inc. 0.17% Reduce -37.8% 3,004 $449K
Aquila Investment Management LLC 0.38% No change 3,000 $448K
Fox Run Management, L.L.C. 0.10% Add +105.2% 2,988 $447K
Los Angeles Capital Management LLC 0.00% Reduce -82.6% 2,959 $442K
Wealth Enhancement Advisory Services, LLC 0.00% Add +22.8% 2,947 $440K
Metis Global Partners, LLC 0.02% Reduce -32.9% 2,940 $439K
Sequoia Financial Advisors, LLC 0.01% Reduce -62.3% 2,910 $435K
Alberta Investment Management Corp 0.00% Reduce -59.6% 2,900 $433K
Horizon Kinetics Asset Management LLC 0.01% No change 2,880 $430K
Prudential PLC 0.00% Reduce -41.0% 2,873 $429K
Greenleaf Trust 0.00% Reduce -2.5% 2,863 $428K
Y-Intercept (Hong Kong) Ltd 0.03% Add +53.3% 2,843 $425K
Aigen Investment Management, LP 0.09% Reduce -88.5% 2,827 $422K
E Fund Management Co., Ltd. 0.03% Reduce -15.8% 2,814 $421K
Janney Montgomery Scott LLC 0.00% Add +47.4% 2,775 $415K
Scientech Research LLC 0.21% New 2,688 $402K
First Trust Direct Indexing L.P. 0.03% Reduce -8.3% 2,656 $397K
Harbor Capital Advisors, Inc. 0.05% Reduce -12.6% 2,568 $384K
Bank Pictet & Cie (Europe) AG 0.01% Add +48.4% 2,562 $383K
Degroof Petercam Asset Management 0.00% No change 2,520 $377K
Moloney Securities Asset Management, LLC 0.05% New 2,389 $357K
Truist Financial Corp. 0.00% Reduce -5.1% 2,351 $351K
Integrated Wealth Concepts LLC 0.01% Add +1.4% 2,320 $347K
Parallax Volatility Advisers, L.P. 0.01% New 2,237 $334K
New York Life Investment Management LLC 0.00% Add +0.9% 2,218 $331K
O'shaughnessy Asset Management, LLC 0.00% Add +9.6% 2,181 $326K
Asahi Life Asset Management Co., LTD. 0.19% New 2,150 $321K
Orion Porfolio Solutions, LLC 0.00% Reduce -15.2% 2,145 $321K
Orion Portfolio Solutions, LLC 0.00% Reduce -15.2% 2,145 $321K
Moody Aldrich Partners LLC 0.05% Reduce -34.9% 2,138 $320K
Monograph Wealth Advisors, LLC 0.05% Reduce -0.6% 2,126 $318K
Altfest L J & Co. Inc. 0.04% Add +1.3% 2,100 $314K
Emerald Advisers, LLC 0.01% Reduce -1.1% 2,070 $309K
Gotham Asset Management 0.00% Reduce -81.1% 2,047 $306K
Proficio Capital Partners LLC 0.03% New 2,046 $306K
Virtus Advisers, LLC 0.16% Add +16.8% 2,043 $305K
Vestcor Inc 0.01% Reduce -27.0% 2,038 $305K
Security National Bank of So Dak 0.18% No change 2,000 $299K
Farallon Capital Management, L.L.C. 0.00% No change 2,000 $299K
Investment Management Corp of Ontario 0.01% Reduce -31.2% 1,985 $297K
Motley Fool Asset Management LLC 0.02% Reduce -3.7% 1,960 $293K
Bleakley Financial Group, LLC 0.01% Reduce -4.3% 1,938 $290K
Simplicity Wealth,LLC 0.01% New 1,934 $289K
American International Group, Inc. 0.00% No change 1,883 $281K
Bridgefront Capital, LLC 0.21% New 1,869 $279K
Loring Wolcott & Coolidge Fiduciary Advisors LLP 0.00% No change 1,905 $278K
Leonteq Securities AG 0.04% Add +318.6% 1,850 $276K
Jefferies Financial Group Inc. 0.01% Add +1161.6% 1,842 $275K
Ontario Teachers Pension Plan Board 0.00% New 1,833 $274K
UniSuper Management Pty Ltd 0.00% Add +100.0% 1,800 $269K
Meiji Yasuda Asset Management Co Ltd. 0.01% Add +27.5% 1,760 $263K
Tower Research Capital LLC (TRC) 0.01% Reduce -74.0% 1,735 $259K
EntryPoint Capital, LLC 0.23% Add +70.2% 1,724 $258K
Cwm, LLC 0.00% Reduce -96.0% 1,722 $257K
Oppenheimer & Co. Inc. 0.00% Reduce -60.8% 1,716 $256K
Acadian Asset Management LLC 0.00% Add +30.3% 1,659 $247K
Beacon Pointe Advisors, LLC 0.00% No change 1,636 $245K
Yousif Capital Management, LLC 0.00% Add +9.7% 1,635 $244K
Cantor Fitzgerald, L. P. 0.06% New 1,584 $237K
Osaic Holdings, Inc. 0.00% Reduce -56.5% 1,563 $234K
Vident Advisory, LLC 0.00% Reduce -16.5% 1,561 $233K
Kennedy Capital Management LLC 0.00% New 1,548 $231K
Humankind Investments LLC 0.06% Add +20.6% 1,532 $229K
Mutual of America Capital Management LLC 0.00% No change 1,519 $227K
North Star Asset Management Inc. 0.01% Reduce -0.3% 1,510 $226K
High Net Worth Advisory Group LLC 0.07% No change 1,500 $224K
Cipher Capital LP 0.10% New 1,490 $223K
Ieq Capital, LLC 0.00% New 1,490 $223K
WINTON GROUP Ltd 0.02% New 1,471 $220K
Westpac Banking Corp. 0.02% Reduce -3.0% 1,467 $219K
Forum Financial Management, LP 0.00% No change 1,457 $218K
Laird Norton Wetherby Wealth Management, LLC 0.01% Reduce -10.9% 1,446 $216K
Abbrea Capital, LLC 0.03% No change 1,425 $213K
Envestnet Portfolio Solutions, Inc. 0.00% Add +3.0% 1,409 $211K
Pearl River Capital, LLC 0.03% Reduce -63.9% 1,400 $209K
Stevens Capital Management LP 0.04% New 1,390 $208K
Kestra Advisory Services, LLC 0.00% Add +7.2% 1,359 $203K
Cigna Investments Inc. 0.04% Add +2.3% 1,352 $202K
Oxford Asset Management LLP 0.23% Reduce -56.1% 1,344 $201K
Peregrine Capital Management LLC 0.00% No change 1,147 $171K
Ossiam 0.00% Reduce -44.4% 1,105 $165K
Plante Moran Financial Advisors, LLC 0.02% No change 1,100 $164K
Signaturefd, LLC 0.00% Reduce -7.6% 1,099 $164K
Rakuten Investment Management, Inc. 0.00% Add +1106.7% 1,086 $162K
Central Pacific Bank - Trust Division 0.02% — 1,050 $161K
Quarry LP 0.06% New 1,000 $149K
TD Waterhouse Canada Inc. 0.00% Add +3.8% 845 $131K
Towarzystwo Funduszy Inwestycyjnych Pzu SA 0.05% No change 850 $127K
Covestor Ltd 0.07% Add +105.0% 732 $110K
Steward Partners Investment Advisory, LLC 0.00% Add +49.0% 715 $107K
Natixis 0.00% New 682 $102K
Allworth Financial LP 0.00% Add +141.2% 591 $88K
Wolverine Asset Management LLC 0.01% New 590 $88K
Spire Wealth Management 0.00% Add +0.5% 583 $87K
1832 Asset Management L.P. 0.00% No change 545 $81K
Prestige Wealth Management Group LLC 0.02% Add +69.8% 472 $71K
IFP Advisors, Inc 0.00% Add +3.1% 470 $70K
Quantbot Technologies LP 0.00% Add +36.0% 434 $65K
Benjamin F. Edwards & Company, Inc. 0.00% Add +8.9% 404 $60K
Alta Advisers Ltd 0.03% No change 400 $60K
Northwestern Mutual Wealth Management Co. 0.00% Reduce -34.2% 346 $52K
Pacer Advisors, Inc. 0.00% New 285 $43K
V-Square Quantitative Management LLC 0.01% No change 274 $41K
EverSource Wealth Advisors, LLC 0.00% Add +28.0% 274 $39K
Parallel Advisors, LLC 0.00% Add +15.2% 243 $36K
Lindbrook Capital, LLC 0.00% Reduce -36.0% 236 $35K
Quadrant Capital Group LLC 0.00% Reduce -24.5% 231 $35K
GAMMA Investing LLC 0.01% Reduce -21.9% 211 $32K
CKW Financial Group 0.00% No change 200 $31K
Rakuten Securities, Inc. 0.01% New 200 $30K
Altitude Crest Partners Inc. 0.01% New 200 $30K
Anchor Investment Management, LLC 0.00% No change 200 $30K
Livforsakringsbolaget Skandia, Omsesidigt 0.00% No change 200 $30K
Quent Capital, LLC 0.00% Reduce -1.2% 171 $26K
Allspring Global Investments Holdings, LLC 0.00% Add +572.0% 168 $25K
Capital Advisors, Ltd. LLC 0.00% Add +1.3% 160 $24K
Liontrust Investment Partners LLP 0.00% Reduce -74.2% 150 $22K
Brown, Lisle/Cummings, Inc. 0.01% No change 125 $19K
Global Trust Asset Management, LLC 0.01% No change 122 $18K
Gradient Investments LLC 0.00% Reduce -1.8% 112 $17K
Clearstead Advisors, LLC 0.00% Reduce -86.5% 110 $16K
Sandy Spring Bank 0.00% Add +41.3% 106 $16K
Riverview Trust Co 0.01% New 104 $16K
Harbour Investments, Inc. 0.00% Reduce -7.3% 102 $15K
Cape Investment Advisory, Inc. 0.01% No change 90 $13K
Principal Securities, Inc. 0.00% Reduce -11.8% 90 $13K
First Horizon Advisors, Inc. 0.00% No change 88 $13K
Annis Gardner Whiting Capital Advisors, LLC 0.00% New 72 $11K
Farther Finance Advisors, LLC 0.00% Reduce -26.6% 69 $11K
Huntington National Bank 0.00% Add +109.4% 67 $10K
Elequin Capital, LP 0.01% New 63 $9K
Global Retirement Partners, LLC 0.00% Reduce -19.2% 63 $9K
Macroview Investment Management LLC 0.01% Add +21.4% 51 $8K
TFC Financial Management, Inc. 0.00% Add +2.0% 51 $8K
St. Johns Investment Management Company, LLC 0.00% No change 50 $7K
Princeton Global Asset Management LLC 0.00% New 50 $7K
Peoples Financial Services Corp. 0.00% No change 50 $7K
MassMutual Private Wealth & Trust, FSB 0.00% Add +26.7% 38 $6K
Bell Investment Advisors, Inc 0.00% Add +9.1% 36 $5K
Parkside Financial Bank & Trust 0.00% Reduce -5.3% 36 $5K
Bogart Wealth, LLC 0.00% No change 36 $5K
Whittier Trust Co. 0.00% Reduce -2.7% 36 $5K
Private Wealth Management Group, LLC 0.00% Add +30.8% 34 $5K
Larson Financial Group LLC 0.00% New 27 $4K
Brown Brothers Harriman & Co. 0.00% Reduce -93.3% 27 $4K
Sachetta, LLC 0.00% No change 19 $4K
Meeder Asset Management Inc. 0.00% New 24 $4K
AdvisorNet Financial, Inc 0.00% Add +187.5% 23 $3K
JFS Wealth Advisors, LLC 0.00% Add +40.0% 21 $3K
Concourse Financial Group Securities, Inc. 0.00% Reduce -19.2% 21 $3K
NewEdge Advisors, LLC 0.00% Add +350.0% 18 $3K
Cetera Trust Company, N.A 0.00% No change 16 $2K
Sunbelt Securities, Inc. 0.00% No change 15 $2K
Blue Trust, Inc. 0.00% Reduce -64.3% 15 $2K
Piscataqua Savings Bank 0.00% No change 15 $2K
Semmax Financial Advisors Inc. 0.00% No change 14 $2K
WFA Asset Management Corp 0.00% No change 14 $2K
Front Row Advisors LLC 0.00% No change 14 $2K
Zions Bancorporation, N.A. 0.00% Reduce -26.3% 14 $2K
Valley National Advisers Inc. 0.00% Reduce -82.6% 15 $2K
Richardson Financial Services Inc. 0.00% New 10 $2K
Raffa Wealth Management, LLC 0.00% No change 13 $2K
Smartleaf Asset Management LLC 0.00% New 10 $2K
Mark Sheptoff Financial Planning, LLC 0.00% New 10 $1K
Colonial Trust Advisors 0.00% New 9 $1K
Avior Wealth Management, LLC 0.00% New 9 $1K
Mather Group, Llc. 0.00% New 7 $1K
FSA Wealth Management LLC 0.00% No change 8 $1K
Janiczek Wealth Management, LLC 0.00% No change 8 $1K
Fifth Third Bancorp 0.00% Add +100.0% 8 $1K
Criterion Capital Advisors, LLC 0.00% No change 7 $1K
Winthrop Capital Management, LLC 0.00% No change 6 $1K
Avion Wealth 0.00% No change 6 $1K
Penserra Capital Management LLC 0.00% No change 9 $1K
SouthState Bank Corp 0.00% New 6 $897
DiNuzzo Private Wealth, Inc. 0.00% No change 6 $897
DT Investment Partners, LLC 0.00% No change 5 $748
MV Capital Management, Inc. 0.00% Add +66.7% 5 $748
SJS Investment Consulting Inc. 0.00% Add +66.7% 5 $748
Montag A & Associates Inc. 0.00% Reduce -28.6% 5 $733
JNBA Financial Advisors 0.00% No change 4 $598
Kayne Anderson Rudnick Investment Management LLC 0.00% No change 4 $598
Abound Wealth Management 0.00% Reduce -25.0% 3 $449
Manchester Capital Management LLC 0.00% No change 3 $449
Versant Capital Management, Inc 0.00% Reduce -66.7% 3 $448
CVA Family Office, LLC 0.00% New 3 $448
True Wealth Design, LLC 0.00% Add +100.0% 2 $299
CoreCap Advisors, LLC 0.00% New 2 $299
Financial Gravity Asset Management, Inc. 0.00% New 1 $213

"% of holder's portfolio" is ALNY's weight in each manager's 13F, not the share of Alnylam Pharmaceuticals Inc. the manager owns.