Ionis PharmaceuticalsIONS
13F holders, Q4 2024 (December 31)355holders +1
41new positions
48sold out
6famous investors
$34.97avg. 13F price*
At the end of Q4 2024, 355 institutions reported holding Ionis Pharmaceuticals Inc. (IONS) in their 13F filings, up 1 from Q3 2024. 41 opened new positions and 48 sold out. The largest holders were FMR LLC ($793.2M), Vanguard Group Inc. ($575.9M) and T. Rowe Price Investment Management, Inc. ($495.4M). 6 famous investors held it, including Cathie Wood (0.3% of ARK Investment Management's portfolio), Ken Griffin (0.1% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Ionis Pharmaceuticals Inc.
- CUSIP
- 462222100
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 41 | $81.9M |
| Exits | 48 | $178.8M |
All 13F filers, Q3 2024 → Q4 2024: 16,487,676 shares bought and 13,800,535 shares sold, net +2,687,141 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 355 holders
| FMR LLC | 0.05% | Add +0.9% | 22,689,491 | $793.2M |
| Vanguard Group Inc. | 0.01% | Add +9.4% | 16,472,539 | $575.9M |
| T. Rowe Price Investment Management, Inc. | 0.31% | Add +0.0% | 14,169,199 | $495.4M |
| BlackRock, Inc. | 0.01% | Add +7.9% | 11,665,548 | $407.8M |
| Capital World Investors | 0.06% | Add +46.5% | 11,465,413 | $400.8M |
| Wellington Management Group LLP | 0.06% | Reduce -0.7% | 8,672,148 | $303.2M |
| Bellevue Group AG | 5.30% | Reduce -0.1% | 7,868,700 | $275.1M |
| State Street Corp. | 0.01% | Add +11.9% | 5,426,413 | $189.7M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -9.1% | 3,826,939 | $133.8M |
| Tweedy, Browne Co LLC | 7.66% | Reduce -6.0% | 3,248,863 | $113.6M |
| Orbimed Advisors LLC | 2.05% | Add +21.2% | 2,817,347 | $98.5M |
| Geode Capital Management, LLC | 0.01% | Add +0.7% | 2,687,248 | $94.0M |
| Citadel Advisors | 0.07% | Add +439.9% | 2,165,916 | $75.7M |
| Deep Track Capital, LP | 2.53% | Reduce -12.1% | 1,933,928 | $67.6M |
| UBS Group AG | 0.01% | Add +1042.3% | 1,917,608 | $67.0M |
| Macquarie Group Ltd. | 0.07% | Reduce -5.3% | 1,769,743 | $61.9M |
| Norges Bank | 0.01% | Reduce -15.4% | 1,714,762 | $59.9M |
| Clearbridge Investments, LLC | 0.05% | Reduce -4.9% | 1,618,220 | $56.6M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +2.7% | 1,481,440 | $51.8M |
| Two Sigma Advisers, LP | 0.11% | Add +1.3% | 1,349,211 | $47.2M |
| Morgan Stanley | 0.00% | Add +1.5% | 1,329,929 | $46.5M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.09% | Add +38.5% | 1,080,341 | $37.8M |
| TD Asset Management Inc | 0.03% | Reduce -3.9% | 1,049,990 | $36.7M |
| ARK Investment Management | 0.30% | Reduce -25.9% | 1,025,260 | $35.8M |
| Two Sigma Investments, LP | 0.08% | Add +0.3% | 921,439 | $32.2M |
| Candriam S.C.A. | 0.17% | Reduce -10.4% | 849,824 | $29.7M |
| Northern Trust Corp. | 0.00% | Add +13.1% | 840,271 | $29.4M |
| Hudson Bay Capital Management LP | 0.21% | Add +7.1% | 821,200 | $28.7M |
| Marshall Wace, LLP | 0.04% | Reduce -57.7% | 812,306 | $28.4M |
| Invesco Ltd. | 0.01% | Reduce -2.7% | 788,599 | $27.6M |
| Millennium Management | 0.02% | Add +79.8% | 774,215 | $27.1M |
| Royal Bank of Canada | 0.00% | Reduce -4.0% | 643,192 | $22.5M |
| Camber Capital Management LP | 0.86% | New | 625,000 | $21.9M |
| Pictet Asset Management Holding SA | 0.02% | Reduce -52.4% | 620,798 | $21.7M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +116.9% | 619,641 | $21.7M |
| Bank of New York Mellon Corp | 0.00% | Add +0.8% | 616,071 | $21.5M |
| J. Goldman & Co LP | 0.75% | Reduce -0.3% | 607,499 | $21.2M |
| AXA S.A. | 0.06% | Add +7.9% | 605,345 | $21.2M |
| Barclays PLC | 0.01% | Reduce -6.4% | 596,072 | $20.8M |
| Vestal Point Capital, LP | 1.23% | New | 595,000 | $20.8M |
| Pinnacle Associates Ltd. | 0.26% | Add +19.3% | 547,642 | $19.1M |
| Groupama Asset Managment | 0.38% | Add +24.3% | 517,191 | $18.1M |
| Great Point Partners LLC | 8.32% | Add +98.0% | 505,007 | $17.7M |
| Bank of America Corp. | 0.00% | Reduce -25.6% | 422,861 | $14.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -26.9% | 415,919 | $14.5M |
| Aberdeen Group plc | 0.03% | Add +32.4% | 401,501 | $14.0M |
| C WorldWide Group Holding A/S | 0.17% | Add +33.3% | 400,000 | $14.0M |
| Ameriprise Financial Inc. | 0.00% | Reduce -2.6% | 387,448 | $13.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +60.5% | 378,208 | $13.2M |
| Schonfeld Strategic Advisors LLC | 0.08% | Add +2.3% | 371,381 | $13.0M |
| Baker Bros. Advisors LP | 0.14% | Add +60.2% | 357,915 | $12.5M |
| Nomura Holdings Inc. | 0.07% | Reduce -21.1% | 357,255 | $12.5M |
| Tocqueville Asset Management L.P. | 0.19% | Reduce -13.4% | 352,140 | $12.3M |
| Wells Fargo & Company | 0.00% | Reduce -3.3% | 331,009 | $11.6M |
| Voloridge Investment Management, LLC | 0.04% | Reduce -16.7% | 316,943 | $11.1M |
| Bank of Montreal | 0.01% | Add +45.9% | 312,146 | $10.9M |
| Nuveen Asset Management, LLC | 0.00% | Reduce -4.5% | 290,954 | $10.2M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -7.3% | 286,279 | $10.0M |
| Jacobs Levy Equity Management, Inc. | 0.03% | Reduce -56.7% | 281,813 | $9.9M |
| Swiss National Bank | 0.01% | Add +8.8% | 279,200 | $9.8M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | Reduce -45.0% | 275,000 | $9.6M |
| Privium Fund Management B.V. | 2.13% | Add +6.4% | 266,794 | $9.3M |
| BNP Paribas Financial Markets | 0.01% | Add +45.2% | 254,521 | $8.9M |
| Artisan Partners Limited Partnership | 0.01% | Reduce -88.7% | 252,635 | $8.8M |
| Siren, L.L.C. | 0.39% | No change | 250,000 | $8.7M |
| Corient Private Wealth LP | 0.01% | Add +0.9% | 239,163 | $8.4M |
| Rafferty Asset Management, LLC | 0.03% | Add +19.4% | 237,337 | $8.3M |
| Sector Gamma As | 2.83% | Add +11.9% | 235,842 | $8.2M |
| Aquatic Capital Management LLC | 0.22% | New | 230,016 | $8.0M |
| Kennedy Capital Management LLC | 0.17% | Add +37.8% | 223,278 | $7.8M |
| Orion Investment Co | 3.01% | Reduce -1.2% | 216,000 | $7.6M |
| Eversept Partners, LP | 0.78% | Reduce -54.4% | 214,952 | $7.5M |
| Susquehanna Fundamental Investments, LLC | 0.13% | — | 213,015 | $7.4M |
| Rhenman & Partners Asset Management AB | 0.76% | Add +9.0% | 212,500 | $7.4M |
| Stifel Financial Corp. | 0.01% | Add +15.9% | 211,493 | $7.4M |
| Renaissance Technologies | 0.01% | Add +7.9% | 205,514 | $7.2M |
| Verition Fund Management LLC | 0.04% | New | 200,184 | $7.0M |
| California Public Employees Retirement System | 0.00% | Reduce -9.3% | 192,130 | $6.7M |
| Rhumbline Advisers | 0.01% | Reduce -2.6% | 191,893 | $6.7M |
| GW&K Investment Management, LLC | 0.06% | New | 187,220 | $6.5M |
| Sicart Associates LLC | 2.32% | Reduce -3.0% | 185,821 | $6.5M |
| Driehaus Capital Management LLC | 0.05% | Reduce -21.7% | 180,002 | $6.3M |
| Citigroup Inc. | 0.01% | Add +140.6% | 169,155 | $5.9M |
| Legal & General Group Plc | 0.00% | Add +6.9% | 168,080 | $5.9M |
| Squarepoint Ops LLC | 0.02% | Add +30.7% | 166,468 | $5.8M |
| Jane Street Group, LLC | 0.01% | Reduce -6.8% | 164,634 | $5.8M |
| Sovran Advisors, LLC | 0.80% | — | 171,812 | $5.6M |
| Sumitomo Mitsui Trust Group, Inc. | 0.00% | Reduce -20.1% | 156,657 | $5.5M |
| Amova Asset Management Americas, Inc. | 0.06% | Reduce -20.1% | 156,657 | $5.5M |
| State Board of Administration of Florida Retirement System | 0.01% | Add +0.8% | 152,315 | $5.3M |
| BLB&B Advisors, LLC | 0.27% | Reduce -0.1% | 152,050 | $5.3M |
| Tang Capital Management LLC | 0.35% | No change | 150,000 | $5.2M |
| Alyeska Investment Group, L.P. | 0.02% | Reduce -11.2% | 150,000 | $5.2M |
| Sonora Investment Management Group, LLC | 0.40% | Reduce -2.9% | 148,776 | $5.2M |
| Assenagon Asset Management S.A. | 0.01% | Add +967.2% | 141,917 | $5.0M |
| California State Teachers Retirement System | 0.01% | Add +6.1% | 133,902 | $4.7M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.02% | Add +606.8% | 125,389 | $4.4M |
| Nicola Wealth Management LTD. | 0.41% | No change | 87,000 | $4.4M |
| Swedbank AB | 0.01% | Reduce -4.0% | 124,237 | $4.3M |
| Woodline Partners LP | 0.03% | New | 107,610 | $3.8M |
| Raymond James Financial Inc. | 0.00% | — | 105,619 | $3.7M |
| State of Wisconsin Investment Board | 0.01% | Add +17.5% | 101,231 | $3.5M |
| Schroder Investment Management Group | 0.00% | Add +79.0% | 100,659 | $3.5M |
| Ghisallo Capital Management LLC | 0.21% | Reduce -75.0% | 100,000 | $3.5M |
| Neuberger Berman Group LLC | 0.00% | Add +49.0% | 96,631 | $3.4M |
| DekaBank Deutsche Girozentrale | 0.01% | No change | 93,807 | $3.3M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -0.2% | 94,157 | $3.3M |
| Voya Investment Management LLC | 0.00% | Reduce -3.4% | 92,531 | $3.2M |
| Deutsche Bank AG | 0.00% | Add +22.7% | 91,901 | $3.2M |
| Twin Tree Management, LP | 0.08% | Add +615.3% | 88,900 | $3.1M |
| Trexquant Investment LP | 0.03% | Reduce -35.1% | 84,913 | $3.0M |
| New York State Common Retirement Fund | 0.00% | Reduce -57.6% | 84,261 | $2.9M |
| HSBC Holdings PLC | 0.00% | New | 83,055 | $2.9M |
| DCF Advisers, LLC | 1.47% | Add +109.8% | 82,882 | $2.9M |
| Granite Investment Partners, LLC | 0.11% | Reduce -13.9% | 73,866 | $2.6M |
| Sei Investments Co. | 0.00% | Reduce -63.1% | 70,091 | $2.5M |
| Treasurer of the State of North Carolina | 0.01% | Add +0.6% | 68,803 | $2.4M |
| Teacher Retirement System of Texas | 0.01% | Add +16.0% | 65,792 | $2.3M |
| Allostery Investments LP | 4.46% | — | 65,000 | $2.3M |
| Janus Henderson Group PLC | 0.00% | Add +8.3% | 63,877 | $2.2M |
| Sphera Funds Management LTD. | 0.41% | No change | 63,821 | $2.2M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +22.1% | 63,206 | $2.2M |
| DAVENPORT & Co LLC | 0.01% | Reduce -17.0% | 62,740 | $2.2M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -51.6% | 62,200 | $2.2M |
| Van Eck Associates Corp. | 0.00% | Add +4.4% | 61,619 | $2.2M |
| Exome Asset Management LLC | 1.61% | New | 61,367 | $2.1M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.05% | Add +63.9% | 60,580 | $2.1M |
| Skandinaviska Enskilda Banken AB (publ) | 0.01% | No change | 59,626 | $2.1M |
| Tema ETFs LLC | 0.83% | — | 56,844 | $2.0M |
| NEOS Investment Management LLC | 0.05% | Reduce -4.0% | 56,844 | $2.0M |
| Police & Firemen's Retirement System of New Jersey | 0.02% | — | 56,695 | $2.0M |
| Public Employees Retirement System of Ohio | 0.01% | Reduce -5.4% | 53,748 | $1.9M |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -23.7% | 53,320 | $1.9M |
| Erste Asset Management GmbH | 0.02% | No change | 51,300 | $1.8M |
| Envestnet Asset Management Inc. | 0.00% | Reduce -10.4% | 52,688 | $1.8M |
| Alliancebernstein L.P. | 0.00% | Reduce -0.1% | 52,136 | $1.8M |
| Fieldview Capital Management, LLC | 0.28% | — | 51,282 | $1.8M |
| Creative Planning | 0.00% | Add +64.9% | 46,803 | $1.6M |
| Qsemble Capital Management, LP | 0.22% | New | 46,573 | $1.6M |
| Handelsbanken Fonder AB | 0.01% | Add +1.9% | 43,811 | $1.5M |
| Profund Advisors LLC | 0.06% | Add +15.9% | 43,559 | $1.5M |
| NJ State Employees Deferred Compensation Plan | 0.18% | No change | 42,000 | $1.5M |
| Liontrust Investment Partners LLP | 0.02% | Reduce -30.2% | 41,621 | $1.5M |
| Arizona State Retirement System | 0.01% | Add +8.8% | 41,147 | $1.4M |
| Private Advisor Group, LLC | 0.01% | Reduce -7.1% | 40,673 | $1.4M |
| LPL Financial LLC | 0.00% | Reduce -5.3% | 40,376 | $1.4M |
| Blair William & Co. | 0.00% | Reduce -14.5% | 39,882 | $1.4M |
| Jump Financial, LLC | 0.03% | New | 39,737 | $1.4M |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -1.6% | 39,214 | $1.4M |
| Capital Counsel LLC | 0.06% | No change | 37,080 | $1.3M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +17.5% | 36,322 | $1.3M |
| Grandfield & Dodd, LLC | 0.08% | Add +3.1% | 35,887 | $1.3M |
| Guggenheim Capital LLC | 0.01% | Reduce -4.8% | 35,373 | $1.2M |
| China Universal Asset Management Co., Ltd. | 0.11% | Add +19.1% | 33,480 | $1.2M |
| KLP Kapitalforvaltning As | 0.00% | — | 29,200 | $1.0M |
| PDT Partners, LLC | 0.09% | Add +116.4% | 28,994 | $1.0M |
| Mariner, LLC | 0.00% | Add +19.6% | 27,661 | $967K |
| BlueCrest Capital Management Ltd | 0.06% | New | 26,200 | $916K |
| Susquehanna International Group, LLP | 0.00% | Reduce -54.5% | 26,064 | $911K |
| Pathstone Holdings, LLC | 0.00% | Reduce -6.3% | 26,058 | $911K |
| XTX Topco Ltd | 0.07% | Add +50.9% | 25,362 | $887K |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 24,083 | $842K |
| Castle Hook Partners LP | 0.02% | No change | 23,940 | $837K |
| SG Americas Securities, LLC | 0.00% | Add +222.5% | 23,927 | $836K |
| D. E. Shaw & Co. | 0.00% | Reduce -84.1% | 23,123 | $808K |
| Jefferies Financial Group Inc. | 0.01% | Reduce -57.6% | 22,381 | $782K |
| Commonwealth Equity Services, LLC | 0.00% | Add +1.7% | 21,826 | $763K |
| Bridgefront Capital, LLC | 0.26% | Add +94.7% | 21,802 | $762K |
| Brevan Howard Capital Management LP | 0.02% | Reduce -25.0% | 21,366 | $747K |
| Canada Pension Plan Investment Board | 0.00% | Add +77.7% | 19,900 | $696K |
| Nicollet Investment Management, Inc. | 0.24% | Reduce -3.0% | 19,786 | $692K |
| Xponance LLC | 0.01% | Add +1.7% | 19,339 | $676K |
| Victory Capital Management Inc. | 0.00% | Reduce -1.9% | 18,004 | $629K |
| Aigen Investment Management, LP | 0.11% | Add +52.6% | 17,723 | $620K |
| Tidal Investments LLC | 0.01% | Reduce -7.9% | 17,407 | $609K |
| NBT Bank, N.A. | 0.04% | No change | 17,050 | $596K |
| Bleakley Financial Group, LLC | 0.02% | Add +1.6% | 16,942 | $592K |
| E Fund Management Co., Ltd. | 0.03% | Add +32.3% | 16,868 | $590K |
| Natixis | 0.00% | New | 16,626 | $581K |
| Walleye Capital LLC | 0.01% | Reduce -86.9% | 16,255 | $568K |
| Campbell & CO Investment Adviser LLC | 0.04% | New | 15,681 | $548K |
| Prelude Capital Management, LLC | 0.05% | New | 15,595 | $545K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 15,589 | $545K |
| Inceptionr LLC | 0.11% | New | 14,390 | $503K |
| Natixis Advisors, LLC | 0.00% | Reduce -32.1% | 14,313 | $500K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +229.2% | 14,157 | $495K |
| North Star Asset Management Inc. | 0.02% | No change | 13,640 | $477K |
| Principal Financial Group Inc. | 0.00% | Add +3.8% | 13,616 | $476K |
| Commerce Bank | 0.00% | Reduce -82.5% | 13,584 | $475K |
| Westmount Partners, LLC | 0.14% | No change | 13,462 | $471K |
| Franklin Resources Inc. | 0.00% | Add +31.0% | 13,301 | $465K |
| Stratos Wealth Partners, LTD. | 0.01% | Add +0.2% | 12,813 | $448K |
| Brown Advisory Inc. | 0.00% | Reduce -0.1% | 12,730 | $445K |
| Horizon Kinetics Asset Management LLC | 0.01% | Add +4.4% | 12,476 | $436K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Add +46.0% | 12,271 | $429K |
| Essential Planning, LLC. | 0.00% | New | 11,440 | $428K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Add +0.6% | 11,327 | $396K |
| Plancorp, LLC | 0.02% | Reduce -1.4% | 11,128 | $389K |
| Amundi | 0.00% | Reduce -91.1% | 11,374 | $388K |
| PNC Financial Services Group, Inc. | 0.00% | Add +11.1% | 10,994 | $384K |
| Significant Wealth Partners LLC | 0.20% | New | 10,905 | $381K |
| Montanova Capital, LLC | 0.01% | No change | 10,800 | $378K |
| Annis Gardner Whiting Capital Advisors, LLC | 0.11% | Add +8.1% | 10,736 | $375K |
| Harbor Advisors LLC | 0.06% | Add +90.9% | 10,500 | $367K |
| Amalgamated Bank | 0.00% | Add +3.4% | 10,292 | $360K |
| &partners | 0.00% | Add +7.4% | 10,317 | $359K |
| Landscape Capital Management, L.L.C. | 0.04% | Reduce -59.6% | 10,270 | $359K |
| Syon Capital LLC | 0.03% | New | 10,119 | $354K |
| Cypress Capital, LLC | 0.10% | No change | 10,000 | $350K |
| Walleye Trading LLC | 0.01% | Add +174.6% | 9,920 | $347K |
| Janney Montgomery Scott LLC | 0.00% | Reduce -12.9% | 9,840 | $344K |
| Fifth Third Bancorp | 0.00% | Reduce -0.4% | 9,531 | $333K |
| Torno Capital, LLC | 0.07% | Add +90.0% | 9,500 | $332K |
| Virtus Advisers, LLC | 0.14% | Add +18.0% | 9,448 | $330K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +20.8% | 9,450 | $330K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | Reduce -53.3% | 9,407 | $329K |
| Jones Financial Companies LLLP | 0.00% | Add +38.9% | 9,338 | $326K |
| MetLife Investment Management, LLC | 0.00% | Reduce -2.2% | 9,160 | $320K |
| Wolverine Trading, LLC | 0.01% | Reduce -23.8% | 8,847 | $309K |
| Teza Capital Management LLC | 0.05% | Reduce -19.6% | 8,525 | $298K |
| Utah Retirement Systems | 0.00% | No change | 8,400 | $294K |
| Man Group plc | 0.00% | Reduce -98.6% | 8,315 | $291K |
| Maryland State Retirement & Pension System | 0.01% | No change | 8,284 | $290K |
| International Assets Investment Management, LLC | 0.02% | No change | 8,207 | $285K |
| Focus Partners Wealth | 0.00% | Add +41.4% | 8,055 | $282K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -20.3% | 7,765 | $271K |
| AlphaCentric Advisors LLC | 0.27% | New | 7,614 | $266K |
| ProShare Advisors LLC | 0.00% | Reduce -13.4% | 7,480 | $262K |
| Comerica Bank | 0.00% | Reduce -2.9% | 7,393 | $258K |
| Sectoral Asset Management Inc. | 0.17% | Reduce -23.7% | 7,200 | $252K |
| Clearstead Advisors, LLC | 0.00% | Reduce -13.3% | 7,185 | $251K |
| Tanaka Capital Management Inc. | 0.55% | Reduce -52.5% | 6,892 | $241K |
| Truist Financial Corp. | 0.00% | Reduce -6.8% | 6,847 | $239K |
| Praxis Investment Management Inc. | 0.02% | New | 6,770 | $237K |
| Silvercrest Asset Management Group LLC | 0.00% | New | 6,617 | $231K |
| Lazard Asset Management LLC | 0.00% | Reduce -71.4% | 6,557 | $228K |
| KBC Group NV | 0.00% | Add +70.3% | 6,484 | $227K |
| EntryPoint Capital, LLC | 0.09% | New | 6,382 | $223K |
| Gotham Asset Management | 0.00% | Reduce -0.0% | 6,260 | $219K |
| Castle Rock Wealth Management, LLC | 0.05% | No change | 6,972 | $216K |
| M&T Bank Corp | 0.00% | Reduce -31.5% | 6,096 | $214K |
| Advisors Asset Management, Inc. | 0.00% | Reduce -1.1% | 6,070 | $212K |
| Quarry LP | 0.04% | New | 6,000 | $210K |
| Vontobel Holding Ltd. | 0.00% | Add +6.6% | 5,865 | $205K |
| Stevens Capital Management LP | 0.08% | New | 5,860 | $205K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | Add +1.2% | 5,654 | $197K |
| Caption Management, LLC | 0.01% | Reduce -79.6% | 5,417 | $189K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -0.5% | 5,262 | $189K |
| Sandia Investment Management LP | 0.33% | No change | 5,000 | $175K |
| US Bancorp \de | 0.00% | Reduce -26.4% | 4,220 | $148K |
| CI Investments Inc. | 0.00% | Add +21.0% | 4,090 | $143K |
| GF Fund Management Co. LTD. | 0.00% | — | 3,315 | $116K |
| Steward Partners Investment Advisory, LLC | 0.00% | Add +49.6% | 3,074 | $107K |
| Venturi Wealth Management, LLC | 0.01% | New | 3,061 | $107K |
| Sterling Capital Management LLC | 0.00% | Reduce -1.1% | 3,010 | $105K |
| Osaic Holdings, Inc. | 0.00% | Reduce -75.7% | 3,986 | $99K |
| Corebridge Financial, Inc. | 0.00% | Reduce -4.1% | 2,759 | $96K |
| Cwm, LLC | 0.00% | Add +17.8% | 2,051 | $72K |
| NewEdge Advisors, LLC | 0.00% | No change | 1,820 | $64K |
| Raiffeisen Bank International AG | 0.00% | — | 1,754 | $62K |
| Twin Lakes Capital Management, LLC | 0.03% | No change | 1,500 | $52K |
| IFP Advisors, Inc | 0.00% | Reduce -6.2% | 1,150 | $49K |
| Horizon Investments, LLC | 0.00% | Add +6.6% | 1,174 | $41K |
| Itau Unibanco Holding S.A. | 0.00% | Add +6.5% | 1,151 | $40K |
| CIBC Private Wealth Group LLC | 0.00% | Reduce -53.6% | 1,125 | $38K |
| Quadrant Capital Group LLC | 0.00% | Add +24.8% | 1,086 | $38K |
| Lindbrook Capital, LLC | 0.00% | Add +183.8% | 1,036 | $36K |
| Sunbelt Securities, Inc. | 0.00% | No change | 1,014 | $35K |
| Manchester Capital Management LLC | 0.00% | Add +18.9% | 1,005 | $35K |
| Parallel Advisors, LLC | 0.00% | Reduce -6.7% | 959 | $34K |
| Huntington National Bank | 0.00% | Add +193.5% | 951 | $33K |
| Signaturefd, LLC | 0.00% | Add +160.0% | 949 | $33K |
| Harbour Investments, Inc. | 0.00% | No change | 900 | $31K |
| Allworth Financial LP | 0.00% | Add +3.0% | 855 | $28K |
| GAMMA Investing LLC | 0.00% | Add +12.3% | 746 | $26K |
| Farther Finance Advisors, LLC | 0.00% | Add +4.8% | 651 | $23K |
| Mather Group, Llc. | 0.00% | Add +26.2% | 651 | $23K |
| Archer Investment Corp | 0.01% | No change | 600 | $21K |
| Laurel Wealth Advisors LLC | 0.00% | No change | 600 | $21K |
| Daiwa Securities Group Inc. | 0.00% | No change | 541 | $19K |
| Danske Bank A/S | 0.00% | Reduce -76.2% | 500 | $17K |
| Riverview Trust Co | 0.02% | Reduce -2.3% | 476 | $17K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +96.6% | 468 | $16K |
| Parkside Financial Bank & Trust | 0.00% | Add +44.1% | 418 | $15K |
| Ascentis Wealth Management, LLC | 0.00% | No change | 400 | $14K |
| Global Trust Asset Management, LLC | 0.01% | Reduce -15.8% | 399 | $14K |
| AlphaMark Advisors, LLC | 0.01% | No change | 369 | $13K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -23.2% | 328 | $11K |
| Elequin Capital, LP | 0.00% | Reduce -25.6% | 325 | $11K |
| Global X Japan Co., Ltd. | 0.00% | Add +26.4% | 297 | $10K |
| Storebrand Asset Management As | 0.00% | No change | 271 | $9K |
| Union Bancaire Privee, UBP SA | 0.00% | — | 265 | $9K |
| MAI Capital Management | 0.00% | New | 260 | $9K |
| Blue Trust, Inc. | 0.00% | Reduce -9.4% | 259 | $9K |
| Covestor Ltd | 0.01% | Reduce -1.6% | 246 | $9K |
| SBI Securities Co., Ltd. | 0.00% | — | 256 | $9K |
| Riggs Asset Managment Co. Inc. | 0.00% | No change | 250 | $9K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +126.2% | 233 | $8K |
| Tidemark, LLC | 0.00% | New | 200 | $7K |
| NFSG Corp | 0.00% | New | 200 | $7K |
| AllSquare Wealth Management LLC | 0.00% | No change | 198 | $7K |
| Whittier Trust Co. | 0.00% | Reduce -10.3% | 192 | $7K |
| Exchange Traded Concepts, LLC | 0.00% | Reduce -8.7% | 178 | $6K |
| Capital Advisors, Ltd. LLC | 0.00% | New | 179 | $6K |
| Whittier Trust Co. of Nevada Inc. | 0.00% | No change | 157 | $5K |
| Pacifica Partners Inc. | 0.00% | No change | 150 | $5K |
| LRI Investments, LLC | 0.00% | No change | 136 | $5K |
| Golden State Wealth Management, LLC | 0.00% | — | 126 | $4K |
| Spire Wealth Management | 0.00% | No change | 125 | $4K |
| GPS Wealth Strategies Group, LLC | 0.00% | No change | 119 | $4K |
| First Horizon Advisors, Inc. | 0.00% | No change | 112 | $4K |
| Arax Advisory Partners | 0.00% | No change | 104 | $4K |
| Transce3nd, LLC | 0.00% | — | 100 | $3K |
| Creekmur Asset Management LLC | 0.00% | No change | 100 | $3K |
| Wilmington Savings Fund Society, FSB | 0.00% | No change | 92 | $3K |
| Orion Capital Management LLC | 0.00% | New | 80 | $3K |
| Brooklyn Investment Group | 0.00% | Reduce -4.8% | 80 | $3K |
| Quent Capital, LLC | 0.00% | No change | 74 | $3K |
| Raleigh Capital Management Inc. | 0.00% | No change | 72 | $3K |
| Global Retirement Partners, LLC | 0.00% | Reduce -28.7% | 72 | $3K |
| Bell Investment Advisors, Inc | 0.00% | No change | 71 | $2K |
| Bogart Wealth, LLC | 0.00% | No change | 71 | $2K |
| Semmax Financial Advisors Inc. | 0.00% | No change | 79 | $2K |
| Principal Securities, Inc. | 0.00% | Add +1575.0% | 67 | $2K |
| Leonteq Securities AG | 0.00% | No change | 63 | $2K |
| Hemington Wealth Management | 0.00% | Reduce -1.2% | 83 | $2K |
| Blume Capital Management, Inc. | 0.00% | No change | 55 | $2K |
| Versant Capital Management, Inc | 0.00% | Reduce -12.7% | 55 | $2K |
| Clear Investment Research, LLC | 0.00% | No change | 51 | $2K |
| Coppell Advisory Solutions LLC | 0.00% | New | 51 | $2K |
| Private Trust Co. NA | 0.00% | No change | 48 | $2K |
| CoreCap Advisors, LLC | 0.00% | Add +73.1% | 45 | $2K |
| MV Capital Management, Inc. | 0.00% | Add +2050.0% | 43 | $2K |
| Wolff Wiese Magana LLC | 0.00% | Reduce -62.7% | 41 | $1K |
| Assetmark, Inc. | 0.00% | New | 32 | $1K |
| Avion Wealth | 0.00% | New | 54 | $1K |
| Raffa Wealth Management, LLC | 0.00% | No change | 28 | $979 |
| Sachetta, LLC | 0.00% | Reduce -72.5% | 27 | $944 |
| Cornerstone Planning Group LLC | 0.00% | New | 25 | $851 |
| Lee Danner & Bass Inc. | 0.00% | New | 22 | $769 |
| TFC Financial Management, Inc. | 0.00% | No change | 21 | $735 |
| Front Row Advisors LLC | 0.00% | No change | 20 | $699 |
| Key Financial Inc | 0.00% | No change | 19 | $664 |
| Larson Financial Group LLC | 0.00% | No change | 18 | $629 |
| Bokf, NA | 0.00% | New | 18 | $602 |
| CENTRAL TRUST Co | 0.00% | New | 15 | $525 |
| Mascoma Wealth Management LLC | 0.00% | New | 14 | $489 |
| WealthTrak Capital Management LLC | 0.00% | — | 10 | $350 |
| Private Wealth Management Group, LLC | 0.00% | No change | 10 | $350 |
| Principia Wealth Advisory, LLC | 0.00% | — | 9 | $315 |
| Rothschild Investment LLC | 0.00% | New | 5 | $175 |
| Caitong International Asset Management Co., Ltd | 0.00% | — | 3 | $105 |
| Cassady Schiller Wealth Management, LLC | 0.00% | New | 2 | $70 |
| AdvisorNet Financial, Inc | 0.00% | No change | 1 | $35 |
| Activest Wealth Management | 0.00% | New | 1 | $35 |
"% of holder's portfolio" is IONS's weight in each manager's 13F, not the share of Ionis Pharmaceuticals Inc. the manager owns.